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A SuperMinds 2014 Talk by Matthieu De Beule (iMinds - Medisip – Ugent).“Surgeons use a 3D-printed heart to save a child’s life”. This is truly a fantastic application of 3D printing that really helped doctors prepare for life-saving surgery And while this is impressive in an of itself, the question is what’s next? Wouldn’t it be cool if the surgeon could actually try out different treatment options to pre-operatively evaluate what would be the best for that specific patient? Applications such as this are no longer science fiction, the good news … it’s possible!
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3D-Printed heart saves the life
of baby John
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John Doe Jr JOHN Doe Sr* *JOHN Doe Sr is a fictitious person with a fictitious disease and a fictitious clinical outcome, any resemblance to a real person, living or dead, is purely coincidental
*Clinical images from Prof Dr Peter de Jaegere, EMC, Rotterdam
Which device size would be the best for JOHN?
26 mm 29 mm
JOHN had a severe complication …
* Kodali et al., 2012, N Engl J Med
Months after implantation
Death
s (
%)
Low leakage
High leakage
chance of dying 100% higher
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Virtual heart saves the life of John Doe Sr
Bigger size decreases leakage with 70%
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Validation
The model can predict the valve morphology
In silico In vivo
0
5
10
15
20
25
Sellers 0, 1 Sellers > 2
Clinically observed leakage
29 pts included, further enrolling
p < 0.05
Pre
dic
ted leakage
The model can predict the valve function
Integration
What have we learned today? ‘
“
’ - P. Huysentruyt
SIZE matters
