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87 N Raymond Avenue #202, Pasadena, CA 91103 contact@metamason.com 415.694.8699 metamason, inc. © Confidential and Proprietary Draft Copy, for Discussion Only Formation To Funding: Starting a 3D Printing MedTech Start-Up w/ NEW YORK SPRING 2016 Leslie Oliver Karpas CEO & Founder Clifford Sarkin CFO/COO & Co-Founder

Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

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Page 1: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Formation To Funding:Starting a 3D Printing MedTech Start-Up w/

NEW YORK SPRING 2016

Leslie Oliver Karpas CEO & Founder

Clifford Sarkin CFO/COO & Co-Founder

Page 2: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Clifford Sarkin CFO/COO & Co-Founder

$80M Exit to MicrosoftDir. OperationsDir. Operations

Page 3: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

3d printing forecast to be a $21B+ by 2020 -Ben Uglow, Morgan Stanley

Siemens predicts 3d printing will become 50% cheaper and 400% faster in the next 5 years

By 2020, healthcare will spend $1.2B on printing a year -Grand View Research

$3d printing business trends

Page 4: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Leslie Oliver Karpas CEO & Founder

Custom CNCs & Machine Vision3D Printing since 1999PSI3D Modeling since 1993

Page 5: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

History

Page 6: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

$600m+ net revenue in 2013, the best selling printed product in the world

90% of the world’s hearing aids are printed, with 10m+ sold to date

a startup doing scan to fit orthotics just closed their series b, w/ $20m+ raised

money in personalization

Page 7: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

bone replacement

Page 8: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

prosthetic limbs

Page 9: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

4d biomaterials

Page 10: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

hearing aids

Page 11: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

mass personalization

Page 12: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

no more least bad for most people

Page 13: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

“3D Printing is hitting the ‘Trough of Disillusionment’... It’s still too hard for common people.” - Jeff Kowalski, Autodesk CTO

Inside 3D Printing, Santa Clara 2014

Core Mission: Create 3D Printing’s Killer App

Page 14: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Page 15: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

?where’s the killer app?

Page 16: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

?printers = early computers

we’re the home brew computer club

Page 17: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

edit publishfax

it’s the content, not the tools

Page 18: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

software is the bridge

Page 19: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Page 20: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

3d printed medicine today

DICOM

.STL /CAD

3D

measurement

fea/cfd simulation

medical model

Page 21: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

scan (input)

fit(interface)

print(instantiate)

Core Philosophy

META-MODERISM

Page 22: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

The hole in capability is durable, soft, and

safe, products.

BIO-COMPATIBLE(suitable for long term skin contact)BIO-INCOMPATIBLE

RIGID

ELASTIC

3d printed bionic earDepartment of Mechanical and Aerospace

Engineering, Princeton University

3d printed hearing aidstarkey

3d-printed dress for dita von teeseMichael Schmidt and Francis Bitonti

kinematicsn-e-r-v-o-u-s system

pla yodathingiverse

mail opening devices

hao-chun huang

tango photo-polymerstratasys

filaflexrecreus

ninjaflexfenner drives

layer wisedepartment of mechanical university of hasselt biomed research institute

titanium eyewearhoet

dental alignerinvisalign

positioning in 3d pringting

Metamason, Inc. © 保密和专有稿件仅供讨论

87 N Raymond Ave. S202, Pasadena, CA 91103, [email protected] +1.415.694.8699

OSA 治疗产品对比

鼻枕式面罩

市场份额

舒适度

气密性

美观性

持续体验

口鼻面罩 下颚前移 口腔加压治疗RESPERE

Page 23: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

print

scan

fitMeta-Moderism in Practice

Page 24: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

POOR SEAL

NOSTRILS ABRADED BY MASK

TANGLED HOSE

cpap issues

STRAPS MARK FACE

Initial Vertical: CPAP Masks

Page 25: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

respere tm: TRULY PERSONALIZED RESPIRATORY DEVICES VIA 3D SCANNING & PRINTING

Page 26: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

NASAL FITTING ADJUSTMENT

ACCESSORY SELECTION

HOSE ADJUSTMENT

BRIDGE DESIGN

STRAP CONFIGURATION

STRAP PLACEMENT

respere features

Page 27: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

respere tm: TRULY PERSONALIZED RESPIRATORY DEVICES VIA 3D SCANNING & PRINTING

Page 28: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Future Vertricals

MEDICAL

SPORTS /FASHION

MILITARY / MUNICIPAL

INTIMATEAPPAREL

Bras / Panties /Body Shapers

Cervical Caps / Menstrual Cups

Breast Pump Nipple Interfaces

Adult Toys

BODY SUITS

Pre-Loaded Workout Gear

Physical Therapy

Bio-Mechanical Enhancement

BODY PADS

Joint Braces

Contact Sports Padding

Protective Gear

Battle Helmets / Armor

Bike Seats

GEAR GRIPS

Golf Clubs

Tennis Rackets

Walking Aids

Equipment Interfaces /

Fire Arm Grips

FACE MASKS

Scuba

Pollution

Augmented Reality / VR

Tactical / Vehicle

Page 29: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Lessons Learned

• Use time as a weapon (never stop shopping)

• The smaller the amount invested, the nearer the exit desired (pitch to your audience)

• Understand your alignment

• What makes a bad investor or good one?

investors

Page 30: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Lessons Learned

• There is no part-time

• Why quit today, when you can quit tomorrow

• Complementary skills & Compatibility are keys

• There is no ‘me’, only ‘we’

entrepreneurs

Page 31: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

Lessons Learned

• Master the greater trends in your ecosystem

• Patents are a financial time bomb

• Never loose the ‘unmet need’ & those processes that have become obsolete under the radar

pro tips

Page 32: Formation to Funding: Conversing with Metamason on Launching a Successful 3D Printed Healthcare Start-Up

87 N Raymond Avenue #202, Pasadena, CA 91103

[email protected] 415.694.8699metamason™, inc. © Confidential and Proprietary

Draft Copy, for Discussion Only

[email protected]

Formation To Funding:Starting a 3D Printing MedTech Start-Up w/

NEW YORK SPRING 2016

Leslie Oliver Karpas CEO & Founder

Clifford Sarkin CFO/COO & Co-Founder