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Selected Zoonotic Diseases Conference Call
July 1, 2009
Selected Zoonotic Diseases Conference Call
July 1, 2009
Psittacosis Compendium - documents and new tests
Kathy Smith, DVM, MPH; State Public Health Veterinarian; Ohio Department of Health, 614-466-0283; [email protected];
Laura Conklin, MD, Medical Officer, Division of Bacterial Diseases, CDC; 404-639-4747; [email protected]
Compendium of Measures To Control Chlamydophila psittaci Infection Among Humans (Psittacosis) and Pet
Birds (Avian Chlamydiosis), 2009
National Association of State Public Health Veterinarians (NASPHV)
This compendium provides information about psittacosis and avian chlamydiosis to public health officials, physicians, veterinarians, the pet bird industry, and others concerned with controlling these diseases and protecting public health. The recommendations in this compendium provide standardized procedures for controlling avian chlamydiosis in birds, a vital step to protecting human health.
http://www.nasphv.org/documentsCompendiaPsittacosis.html
2009 Updates• Routine prophylactic antibiotic treatment is now discouraged as it
may cause adverse effects and could generate resistant strains of C. psittaci and other bacteria
• More emphasis is placed on recommending doxycycline over other tetracycline antibiotics for the treatment of avian chlamydiosis
• Avian facility managers to provide employees with simple, concise written treatment procedures to ensure treatment success.
• New testing methodologies may better discriminate the known genotypes of C. psittaci
• Change to the CSTE human case definition.
• .
Psittacosis – case definition
Confirmed: An illness characterized by fever, chills, headache, cough, and myalgia, which is supported by a history of known or suspected exposure to sick birds and is laboratory confirmed by either
– Isolation of Chlamydophila psittaci from respiratory specimens (i.e. sputum, pleural tissue or fluid) or blood, or
– Fourfold or greater increase in antibody (IgG) against C. psittaci by complement fixation (CF) or microimmunofluorescence (MIF) between paired acute- and convalescent-phase serum specimens obtained at least 2-4 weeks apart.
Probable:
An illness characterized by fever, chills, headache, cough and myalgia with known exposure to birds that has either
– Supportive serology (e.g. C. psittaci antibody titer [IgM] of greater than or equal to 32 in at least one serum specimen obtained after onset of symptoms), or
– Detection of C. psittaci DNA in a clinical specimen (e.g. respiratory secretions or pleural fluid) via amplification of a specific target by PCR assay.
JOURNAL OF CLINICAL MICROBIOLOGY, Jan. 2009, p. 175–181 Vol. 47, No. 1
Genotyping of Chlamydophila psittaci by Real-Time PCR and High-Resolution Melt Analysis
Stephanie L. Mitchell,1 Bernard J. Wolff,1 W. Lanier Thacker,1 Paula G. Ciembor,2 Christopher R. Gregory,2 Karin D. E. Everett,3 Branson W. Ritchie,2 and Jonas M. Winchell1*
Respiratory Disease Branch, Centers for Disease Control and Prevention, Atlanta, Georgia1; Infectious Diseases Laboratory, College of Veterinary Medicine, University of Georgia, Athens, Georgia2; and Ameritek USA, Everett,
Washington3
Human infection with Chlamydophila (Chlamydia) psittaci can lead to psittacosis, a disease that occasionally results in severe pneumonia and other medical complications. C. psittaci is currently grouped into seven avian genotypes: A through F and E/B. Serological testing, outer membrane protein A (ompA) gene sequencing, and restriction fragment length polymorphism analysis are currently used for distinguishing these genotypes. Although accurate, these methods are time-consuming and require multiple confirmatory tests. By targeting the ompA gene, a real-time PCR assay has been developed to rapidly detect and genotype C. psittaci by light-upon-extension chemistry and high-resolution melt analysis. Using this assay, we screened 169 animalspecimens; 98 were positive for C. psittaci (71.4% genotype A, 3.1% genotype B, 4.1% genotype E, and 21.4% unable to be typed). This test may provide insight into the distribution of each genotype among specific hosts and provide epidemiological and epizootiological data in human and mammalian/avian cases. This diagnostic assay may also have veterinary applications during chlamydial outbreaks, particularly with respect to identifying the sources and tracking the movements of a particular genotype when multiple animal facilities are affected.
The Psittacosis Compendium CommitteeCommittee:• Kathleen A. Smith, DVM, MPH, Chair• Mary Grace Stobierski, DVM, MPH, DACVPM• Leslie A. Tengelsen, PhD, DVM• Colin T. Campbell, DVM• Julia Murphy, DVM, MS, DACVPM Consultants to the Committee• Laura Conklin, MD (Centers for Disease Control and Prevention)• Keven Flammer, DVM, DABVP (Association of Avian Veterinarians)• Dana Cole, DVM, PhD, DACVPM (Council of State and Territorial Epidemiologists)• Branson W. Ritchie, DVM, PhD, DABVP (Association of Avian Veterinarians)• Thomas N. Tully Jr., DVM, MS, DABVP (Association of Avian Veterinarians)• Tracy S. DuVernoy, DVM, MPH, DACVPM (AVMA Council on Public Health and
Regulatory Veterinary Medicine)• Thomas M. Edling, DVM, MSpVM (Pet Industry Joint Advisory Council)
Questions or [email protected]
(614) 466-0283
Kate Stenske, DVM, PhD, Dip ACVIM; Small Animal Internal Medicine, Assistant Professor, Kansas State University, 785-532-4282, [email protected]
Selected Zoonotic Diseases Conference Call
July 1, 2009
E. coli sharing between dogs and owners
Jeff Bender, DVM, MS, Dipl ACVPM, College of Veterinary Medicine, University of Minnesota, 612-625-6203, [email protected]
Selected Zoonotic Diseases Conference Call
July 1, 2009
MRSA and Pets
Sheila Saldeen, Medical/Science Writer, American Veterinary Medical Association 847-285-6740; [email protected]
Kimberly May, DVM, AMVA; [email protected]
Selected Zoonotic Diseases Conference Call
July 1, 2009
MRSA’s Emerging Role as a Zoonotic Disease
Richard Franka, PhD, Division of Viral and Rickettsial Diseases, CDC; [email protected]; 404-639-0857
Selected Zoonotic Diseases Conference Call
July 1, 2009
New ACIP recommendations regarding rabies vaccination – http://www.cdc.gov/RABIES/news/2009-06-24_ACIPvote.html
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Selected Zoonotic Diseases Conference Call
July 1, 2009
