43
VIVO: Data, Tools and Community for Research Discovery

5-pln-1520-Conlon

  • Upload
    med20su

  • View
    1.173

  • Download
    0

Embed Size (px)

DESCRIPTION

 

Citation preview

Page 1: 5-pln-1520-Conlon

VIVO: Data, Tools and

Community for Research Discovery

Page 2: 5-pln-1520-Conlon

Learned a field, learned the scientific method, did

science

Page 3: 5-pln-1520-Conlon

Science and Scientists

Page 4: 5-pln-1520-Conlon

But then …

Page 5: 5-pln-1520-Conlon
Page 6: 5-pln-1520-Conlon

PubMed adds

700,000 articles

each year

Page 7: 5-pln-1520-Conlon

The Problems Got Hard

Page 8: 5-pln-1520-Conlon

Data Got Big (IDR Slide)

Page 10: 5-pln-1520-Conlon
Page 11: 5-pln-1520-Conlon

How do we respond?

Page 12: 5-pln-1520-Conlon
Page 13: 5-pln-1520-Conlon

The FANTOM Consortium & Riken Omics Science Center, The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line Nature Genetics 41, 553 - 562 (2009)

Page 14: 5-pln-1520-Conlon

Clinical Trial

Page 15: 5-pln-1520-Conlon

Collaboration

Page 16: 5-pln-1520-Conlon

Implementation Research

Page 17: 5-pln-1520-Conlon

Mentoring

Page 18: 5-pln-1520-Conlon

How can we know what is going on,

build teams, solve problems?

Page 19: 5-pln-1520-Conlon

Research Discovery

ResearchDiscovery

Page 20: 5-pln-1520-Conlon
Page 21: 5-pln-1520-Conlon

… And the connections between them

Page 22: 5-pln-1520-Conlon

How can we create a world platform for research

discovery?

Page 23: 5-pln-1520-Conlon

Data

Page 24: 5-pln-1520-Conlon

Tools

Page 25: 5-pln-1520-Conlon

Community

Page 26: 5-pln-1520-Conlon

VIVO: Data, Tools and Community

Page 27: 5-pln-1520-Conlon

VIVO is open standards and open linked data regarding science – people, papers/products,

funding, events/presentations, resources, projects/studies, data, concepts – and the

relationships between them

VIVO is open source, community maintained software tools for research discovery and

networking

VIVO is a world community of collaborators – scientists, implementers, developers

Page 28: 5-pln-1520-Conlon

Ontology Process

Page 29: 5-pln-1520-Conlon

Harvesting Data

Page 30: 5-pln-1520-Conlon

Simple tools for presentation, traversal,

search

Page 31: 5-pln-1520-Conlon

Tools using linked open data

Page 32: 5-pln-1520-Conlon

ScienceMap. Examine collections of publications for individuals, work groups, institutions

Page 33: 5-pln-1520-Conlon

processOrg<-function(uri){ x<-xmlParse(uri) u<-NULL name<-xmlValue(getNodeSet(x,"//rdfs:label")[[1]]) subs<-getNodeSet(x,"//j.1:hasSubOrganization") if(length(subs)==0) list(name=name,subs=NULL) else { for(i in 1:length(subs)){ sub.uri<-getURI(xmlAttrs(subs[[i]])["resource"]) u<-c(u,processOrg(sub.uri)) } list(name=name,subs=u) }}

VIVO produces both HTML and RDF

Software reads VIVO RDF and displays

Page 34: 5-pln-1520-Conlon

Augmenting data

Page 35: 5-pln-1520-Conlon

VIVO Searchlight

Page 36: 5-pln-1520-Conlon

This figure at right displays “collaborative publications” found at 2 or more Researcher Networking websites.  The idea that institutions don't work together and that biomedical research is conducted in silos is not true. Researchers, even when separated by great distances, are in fact willing to work together, and this visualization demonstrates that they often do. 

Contact: Nick Benik ([email protected]), Harvard Medical School, Boston, MA. URL: http://xcite.hackerceo.org/VIVOviz

Inter-institutional Collaboration Explorer

Page 37: 5-pln-1520-Conlon

CTSAs

Page 38: 5-pln-1520-Conlon

USDAUSDA

Page 39: 5-pln-1520-Conlon

APA

Page 40: 5-pln-1520-Conlon

China

Page 41: 5-pln-1520-Conlon
Page 42: 5-pln-1520-Conlon

How can you get involved?

Join us at http://vivoweb.org

Page 43: 5-pln-1520-Conlon

Photo Credits2. Jackson Laboratory scientist wins Shaw Prize, "Nobel of the East“ (1960) http://www.jax.org/news/images/pressimages/300dpi_images/coleman/coleman1960.jpg3. Biochemistry at Stanford. From the Stanford Biochemistry web site. 5. Francis Collins. From the NIH web site.7. Courtesy of UF Health Science Center News and Communications14. http://apod.nasa.gov/apod/ap080225.html17. Institut Pasteur Korea Conducts Special 'IPK Life Science Mentoring' Program . http://ip-korea.org 20. Courtesy of Weill Cornell Medical College21. Figure by M. Conlon24. Bruckner Building Supply web site. http://brucknernyc.com/our-products/in-the-yard/25. First annual VIVO Conference. https://

picasaweb.google.com/110849244647388519713/FirstAnnualVIVONationalConference2010?authkey=Gv1sRgCP6K8LDBpOrKLg#551275718424189315438. Abraham Lincoln Building of the Unites States Agricultural Library. http://en.wikipedia.org/wiki/File:United_States_National_Agricultural_Library.jpg40. VIVO map by M. Conlon41. Second annual VIVO conference. Photographs by M. Conlon42. The VIVO team outside the Gaylord during the great DC quake of 2011. 8/22/2011. Photograph courtesy of Michelle Issing.