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Human Factors in the Design and Evaluation of Bioinformatics Tools Naelah Al-Ageel, Areej Al-Wabil, Ghada Badr, Noura AlOmar College of Computer and Information Sciences King Saud University, Riyadh, Saudi Arabia [email protected]

Human Factors in the Design and Evaluation of Bioinformatics Tools

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Human Factors in the Design and Evaluation of Bioinformatics Tools

Naelah Al-Ageel, Areej Al-Wabil, Ghada Badr, Noura AlOmar

College of Computer and Information SciencesKing Saud University, Riyadh, Saudi Arabia

[email protected]

Bioinformatics domain

Growing complexity of biological data

Interdependencies in biological data

Revolutionary domain

Large volumes of biological data sets

Less structured data

1

2

3

4

5

2

Properties of Bioinformatics Systems

Bioinformatics systems:

• Integrate data from many sources

• Present data in different forms

• Process a variety of file formats

• Visualize biological data at molecular andgenome levels

3

Usabilityconsiderations

Responsiveness

Learnability

Accessibility

Understandability

Ease to useEffectiveness

Efficiency

Scalability

Platform independency

4

Contribution

Defining a criteria for building usable bioinformatics systems that takes into consideration:

1. Computational metrics

2. Cognitive and perceptual abilities of the users

Conducting a heuristic evaluation on bioinformatics systems

Conducting a comparative evaluation of many Usability Evaluation Methods

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Usability Inspection of Existing Bioinformatics Online Motif Discovery

and Localization Tools

“Heuristics Evaluation Study”

First Impression

Interacting with Results & Visualization

Query\ Results Forms

Ideal Heuristics

Bioinformatics

Usability

Cross-domain

Target Experts

Sequential Motif Localization

“FIMO Tool”

Sequential Motif Discovery

“MEME Tool”

Structural Motif Localization

“RNAMST”

Structural Motif Discovery

“RNAPromo”

Bioinformatics Tools Evaluation Surveys7

Study Results

Functional Recommendations

User Interface Recommendations

Usability Issues/Problems Good Usability Features

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Usability Issues

Minor

“1”

Serious

“2”

Major

“3”

Critical

“4”

Failure

“5”Total

MEME 16 7 4 0 1 28

FIMO 11 14 4 2 5 36

RNAMST 10 9 11 1 3 34

RNAPromo 19 6 2 2 0 29

Total 56 36 21 5 8 126

99

Effectiveness of Heuristics Evaluation in Bioinformatics

The heuristic evaluation was shown to be an effective usabilityevaluation method for the usability assessment ofbioinformatics tools and identifying usability issues that impactthe users’ satisfaction.

It doesn't produce fixes to the usability problems.

Easy to generate design recommendations according to experts’suggestions after interacting with the systems or beingintroduced to the tools in interactive sessions.

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The Need for Applying Usability in Bioinformatics Tools

Improved interaction design - decreasing processing time

Easing the transition to new versions of existing systems

Improving human performance and productivity

Ensuring better quality of work

Minimizing the impact of user error in data entry

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Usability Goals and Metrics

Cognitive Perspective Computational Perspective

• Time to Complete a Task

• Number of Achromous

• Number of Feedback Functions per site

• Home Page Reference

• Layout Complexity

• Overall Density

• Number of Font Types used

• Number of Ways to Perform a Task

• Percent of Favorable User Comments

• User Subjective Rating

• Ease of use

• Overall satisfaction

• Number of Mouse Clicks to complete

the task

• Completion rate efficacy

• Number of commands used

• Error Frequency

• Task Effectiveness

• Task Completion

• Broken Link Count

• Rate of Error Messages

• Number of reusable components

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Usability Evaluation Methods(UEMs)

Aims of the Usability Evaluation Methods

Investigate the usability of Bioinformatics tools by systematicallyanalyzing user perception and behavior acquired in task-basedusability sessions.

Perform this experimental evaluation study based on theinteraction mode(s) of the proposed system.

Improve the quality of bioinformatics tools by conducting acomparative review of the expected outcomes.

Check whether the system meets functional and non-functionalrequirements.

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Examples of the Usability Evaluation Methods Applied in Bioinformatics Tools

# Type of UEM Features

1 Morae StudyAudio, screen recorder, and usability analysis system in Morae manager

2 Eye Tracking StudyTracking eyes movements, usability

analysis system in Tobii SW

3 Observation Interaction with the system

4 Direct questions Opinions and recommendations

5 Post-test questionnaire Positive and negative feedback

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Conclusion

• Designing usable bioinformatics systems will help in:– Reducing the cognitive overload of the users– Increasing the responsiveness of these systems– Obtaining satisfactory user experiences

Thank You!

Human Factors in the Design and Evaluation of Bioinformatics Tools

Naelah Al-Ageel, Areej Al-Wabil, Ghada Badr, Noura AlOmar

College of Computer and Information SciencesKing Saud University, Riyadh, Saudi Arabia

[email protected]