THE ENHANCEMENT OF ALUMINUM SURFACE AREA BY POLYMERS TEMPLATE ASSISTANCE

Prof. OtañoRISE Spring 2015Sara DiazPatricia RodriguezCamille RuizJustin Cotto

SIGNIFICANCE

Cancer therapy and bio imaging enhancement:Theranostic probesAuNP’s are biocompatibleHave vivid optical properties, and the flexibility to have different molecules and materials attached to their shellScattering: AuNP’s become visible to imaging processesAbsorption: Phototermal ablation Minimal damage to body cellsGold nanoshells are shuttled into tumors by phagocytosisA macrophage is formed

Alternative: Placing drugs inside nanoparticle and using it as a

vehicle Accomplished by coating outside of a nanoparticle

with iron oxideOnce the tumor area is coated with drug filled nanoparticles, they are activated

(Loo 2005)

NANOSHELLS UTILITY THERAPY

TECHNIQUES UTILIZED

Electrospinning Cellulose Acetate Poly(vinyl alcohol) –

Poly(acrylic acid) Regenerated Cellulose

Sputtering Deposition

ELECTROSPINNING

(Ning et. al. 2013)

SPUTTERING UTILITIES AND ADVANTAGES

Utility: Semiconductor industries Optical applications: glasses and telescopes Thin film transistors Low emissivity coatings on glass Fabrication of CD’s and DVD’s Efficient Photovoltaic solar cells

Advantages: Materials with very high melting points are easily

sputtered. Sputtered films typically have stronger adhesion on the

substrate Target contains large amount of material and is

maintenance free Sputtering sources contain no hot parts and are compatible

with reactive gases Size and relative thickness of the nanoshell can be

controlled by changing reaction time and plating concentration

PROBLEM

Which polymer is easier to detach from the deposited Aluminum, in order to acquire an Aluminum nano-shell?

HypothesisCellulose acetate detaches easily. Poly(vinyl alcohol) –Poly(acrylic acid) will only detach when soaked in water.Regenerated cellulose will not detach.

METHODOLOGY

SPUTTERING DEPOSITION

METHODOLOGY

DETAILED METHODOLOGY

METHODOLOGY

METHODOLOGY

METHODOLOGY

 

Deionized water

Deionized water + Ethanol

RESULTS

✓Obtained:✓Deposition of Al on fibers’ surface

✓Technical Issues

CONCLUSION

✓Hypothesis was unable to be proven

✓Future projects:✓Evaluation of fibers through electron

microscope✓Characterization of fiber morphology✓Comparison of optimal templates

CITED LITERATURE

Loo C, Lowery A, Halas N, West J, Dezek R. 2005. Immunotargeted Nanoshells for Integrated Cancer Imaging and Therapy. Nano Lett. [Internet; cited May 14]. Doi: 10.1021/nl050127s. Recovered at: http://faculty.washington.edu/markeh/MSE599/Loo_Nanolett_2005.pdf

Ning Z, Xiongbiao C. 2013. Biofabrication of Tissue Scaffolds in book entitled. Advances in Biomaterials Science and Biomedical Applications. Recovered at: http://ppl.ippt.gov.pl/18-few-words-about/17-electrospinning

ACKNOWLEDGMENTS

RISE PROGRAM Dr. Eneida Diaz Dr. Elena Gonzalez Mr. Giovanni Cruz

Professor Ota-o and his students: Xavier Ortiz Normarieli Passalacqua Alejandra De Jesus

THE ENHANCEMENT OF ALUMINUM SURFACE AREA BY POLYMERS TEMPLATE ASSISTANCE

Prof. OtañoRISE Spring 2015Sara DiazPatricia RodriguezCamille RuizJustin Cotto