1. Build medical sensing capabilities to enable bettertrauma and critical care in austere (battlefield, disaster,rural) and definitive care environmentsLLNL-PRES-507331This work was performed under the auspices of theU.S. Department of Energy by Lawrence LivermoreNational Laboratory under contract DE-AC52-07NA27344.Lawrence Livermore National Security, LLC

2. Electromagnetic sensor Sends out pulses and looks for reflectedLawrence Livermore National LaboratoryRadarecho signals Used for motion detection, localization,and imaging 3. 00.5143210-1-20 0.5 1 1.5 2 2.5 3 3.5 4diagnose trackingLawrence Livermore National Laboratoryout of hospital caresituationalawarenesssearch and rescueimaging123 4. Various motion detection measurements made through rubbleat Disaster City, TexasLawrence Livermore National LaboratoryBreathing signalSubject lying within concrete rubble pile;Fourier transform indicates strong breathingsignal through concrete slabs. 5. 2001 WTC-NYC 2005 KatrinaLawrence Livermore National Laboratory 6. Case study of healthy volunteerLive/dead detection for combatcasualty careHigh potential to benefit generalpublic health monitoringSubject in standing positionRespiratory and cardiacrhythm is readily observableImpulse rhythm tracks wellwith EKG and pulse oximeterJohn Chang in collaboration with Walter Reed Army Institute ofResearch, Dr. FJ PearceLawrence Livermore National Laboratory 7. Small and compactLawrence Livermore National Laboratory10.50-0.5-1-1.50 50 100 150L parietal R parietalR LHematomaCT AxialMRI CoronalNormalIn-field trauma diagnosis for combatcasualty careHigh potential for civilian application foremergency and critical caresCurrent Collaborations with UC Davis Medical Center andNeurosapient, Inc.Chronic subduralhematomaBilateral asymmetrySensitivity topositioningSignal attenuationPeak shift to therightSignal amplitude(V)Skull Intracranial 8. Lawrence Livermore National LaboratoryVocal foldmachineryRear section oftracheal wallCheek andSinus wallmotions 9. Early device ConceptCurrently CRADALawrence Livermore National LaboratoryDetroit Sinai-Grace Hospital:Dr. Robert Dunne, MD, Clinical PIDetroit Receiving Hospital:Dr. Phillip Levy, MD, Clinical PI25 Patients (50 sides): 28 Patients (56 sides):18 Patients without a pneumothorax 21 Patients without a pneumothorax7 Patients with a pneumothorax 7 Patients with a pneumothorax92% (23 of 25 patients) correlationwith radiographic results89.3% (25 of 28 patients) correlation withradiographic results2 Patients with false positives 2 Patients with false positive0 false negatives 1 Patient with false negativeOut of hospital diagnosis for traumatic chest injuriesLLNL in collaboration with Electrosonics Medical, Inc, Detroit Sinai-GraceHospital, and Detroit Receiving Hospital2007 R&D 100 Award,2008 Federal Laboratory Consortium AwardCombined SummaryTotal Patients (sides) 53 Patients (106 sides)Total Correct Patients 48%Total Incorrect Patients 5%Overall Patient Accuracy 91%Total Correct Sides 90%Total Wrong Sides 16%Overall Sides Accuracy 85%Chest x ray of a pneumothorax. [Ref. Educational Computing forHealth Technologies teaching web site, Michigan State University]Note the pleural line visible on the patients right side (image leftside). 10. Suitable for use with humans Low power At least 100 times less than cell phone(< 0.001 mW/cm2) Non-ionizing radiation Non-invasive No skin contactSuitable for use in remote locations, difficult terrain Portable Battery operated Cost effectiveLawrence Livermore National LaboratoryMUIR Technology SpecificationsFrequency: GHz rangePulse repetition rate: 2x106 pulses/secPulse duration: 2x10-10 sec (200ps)Duty factor: 0.0004Peak power: 2.5mW/cm2Peak energy per pulse: 5x10-7 microJ/cm2 11. Can perform multiple functions Sensing (motion, breathing, heart-rate, bleeding, voiceproduction, ) Localization (position fixing) Imaging Advantages: Small size Low power High resolution Non hazardousLawrence Livermore National Laboratory