Current and future animal vaccine research activities at ILRI

Vish Nene8 International Congress on Ticks and Tick-Borne Pathogens (TTP8)

and 12 Biennial Conference, South Africa, 24-29 August 2014

Priority diseases targeted by the ILRI Vaccine Biosciences group

African swine fever (ASF) – swine African disease threatens the global $150 billion/year pig industry

Contagious bovine pleuropneumonia (CBPP) – cattle Regional losses to CBPP amount to ~ $60 million/year

East Coast fever (ECF) – cattle Regional losses exceed $300 million/year; kills ~ 1million cattle/year

Peste des petits ruminants (PPR) – small ruminants Losses in Kenya alone amount to ~ $13 million/year

Rift Valley Fever (RVF) – small ruminants, cattle and human 2006/7 outbreak in Kenya cost ~ $30 million

o 309 human cases in Kenya, Somalia and Tanzania; 140 deaths

Diagnostics are key components of a vaccine program New and more user-friendly tests – evidence based control programs

Vaccines save lives and livestock and contribute to food security and poverty alleviation

ILRI’s vaccine R & D pathway to impact

ILRI’s comparative advantage is mainly in the discovery phase to proof-of-principle under laboratory and field conditions.

Different entry points in pathway depending on disease targeted for control. Improvement of existing vaccines Development of subunit vaccines Laboratory and field based diagnostics

ILVAC – planting the orchard (ilvac.net)

Vaccines are difficult to make and take time

Establish key principles in livestock vaccinology and capacity

ILVAC - vaccine technologies (ilvac.net)

The ILRI Vaccine Biosciences group

The presentation has a Creative Commons licence. You are free to re-use or distribute this work, provided credit is given to ILRI.

Better lives through livestockilri.org