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Raksa Andalib HiaID:11146010
Pharmacology II
• What is Vitamin ?
Introduction
Chemistry of vitamin E
structure
structure
Sources of vitamin
Sunflower Seeds
• One ounce of dry-roasted sunflower seeds delivers 7.4 mg of vitamin E.
• Almonds (7.3 mg of vitamin E per ounce)
• Hazelnuts (4.3 mg of vitamin E per ounce)
• peanuts (2.2 mg of vitamin E per ounce)
• Pine nuts (One ounce of pine nuts contains 2.6 mg of vitamin E)
Turnip Greens
• A half cup has 2.9 mg of vitamin E
Tomatoes
• A quarter cup of tomato paste has 2.8 mg of vitamin E.
Avocado
• Half an avocado has 2.1 mg of vitamin E and 161 calories.
Pharmacological properties
1.Prevention of oxidative stress
2.Supporting healthy skin
3.Vitamin E inhibits platelet aggregation
4.Vitamin E may be involved in signal transduction in neuronal cells
Therapeutic indications
• Angina pectoris
• Acne
• Alzheimer’s disease
• Cancer
• Cataracts
• complications in late pregnancy
• Diabetes
• Psoriasis
• Parkinson’s disease
• Respiratory infection etc.
Contraindications
• Contraindications have not yet been identified.
Interactions
1. Vitamin E may increase the anticoagulant effect of warfarin.
2. may decrease the benefits of atorvastatin therapy.
3. Plasma levels of vitamin E may be lowered by anticonvulsants.
Nutrient Interactions
1. Vitamin C
2. Glutathione
3. Selenium
4. Vitamin B3
Deficiency syndrome
1.digestive system problems
2.peripheral neuropathy
Side effects
• High doses of vitamin E may prolong bleeding time.
Hypervitaminosis
1. Intestinal cramps
2. Diarrhea
3. Fatigue
4. Double vision
5. Muscle weakness
Sources
1. http://www.whfoods.com/genpage.php?tname=nutrient&dbid=111
2. http://painandbrainhealingcenter.com/vitaminearticle.html#.UnnXhHCBlfB
3. http://news.vanderbilt.edu/2012/07/high-consumption-of-vitamin-e-may-lower-liver-cancer-risk/
4. http://www.antioxidantsdetective.com/vitamin-e-facts.html5. http://www.webmd.com/vitamins-supplements/ingredientmono-
954-VITAMIN%20E.aspx?activeIngredientId=954&activeIngredientName=VITAMIN%20E
Thank you.
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