Stem Cells for Orthopedic Conditions

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Stem Cells for Orthopedic Conditions

Email: [email protected] Mob: +91 9811011690 W: StemGenn.com

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http://StemGenn.com

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Website : www.stemgenn.com | Email : [email protected] | Phone : +91 9910596674

Stem cells for orthopedic conditions

There are a lot of orthopedic conditions and injuries that presently have limited treatment options available.

Here regenerative technologies comes up as a ray of hope among surgeons for the treatment by functionally repairing the tissues and organs using growth factors, stem cells and products developed by genetic engineering with the advancement in the stem cells research field .

The purpose of this presentation is to first provide idea about the orthopedic conditions along with the therapeutic potential of stem cells to treat these diseases.

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What orthopedic condition is?

Orthopedic condition basically refers to the injuries and diseases of the body's musculoskeletal system. This complex system includes your bones, joints, ligaments, tendons, muscles, and nerves and allows you to move, work, and be active.

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Aging, exercise, sports and injuries cause excessive wear and tear of the body. As we age, the process of repair is slowed down due to reduced production of Mesenchymal Stem Cells (repair cells). This causes the joints’ elastic tissue to become stiff and lose its elasticity, thereby increasing its susceptibility to damage.

This problem can be treated with stem cell therapy, where your own body’s cells can be used to repair and promote healing of degenerated or injured joints.

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Stem cell therapy in Orthopedics is currently being used in conditions such as:

• Osteoarthritis (degenerative joint disease)• Spinal cord injuries• Chronic tendonitis (inflammation of the elastic tissue that

connects muscle to bone) • Bone fractures• Degenerative vertebral discs

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Stem Cell Therapy and Orthopedic Issues

Stem cells are the basic cells of the human body and have the ability to divide and become more specialized cells—such as bone, blood, or muscle due to which they are having very profound effect in the field of medicine.

Apart from this, the reimplantation process of stem cells into the same person from whom the cells has been obtained also increases the stem cells potential by reducing and eliminating the risk of infection.

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Stem cells may be distinguished from other cells by the following characteristics:

• They have the ability to self-renew.• They can continue to divide for a longer period of time.• Under certain conditions, they can be induced to

differentiate into specialized cells with distinct functional characteristics (phenotypes) including, cardiac, liver, fat, bone, cartilage, nerve, connective tissue cells and many more.

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Researchers found that Mesenchymal Stem Cells (MSC’s) obtained from the adipose (fat) tissues have the capacity to detect changes in the body which are causing pain or dysfunction, and to respond and communicate with the local environmental needs to provide the correct therapy needed for healing. These adult stem cells are commonly referred to as “repair cells” for their ability to heal injured organs or body parts, their primary functions being:

• Acceleration of tissue repair process• Stimulates tissue regeneration• Decreased inflammation the damaged area.• Prevention of further cell death• Creation of new blood vessels

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Introducing patient’s own stem cells into damaged area can stimulate new blood flow in that particular area and reduce inflammation. The stem cells then enhance the process of healing. Stem cells lead to the use of biological cells and healing capabilities of the human body to treat the medical condition.

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Stem cells for orthopedic conditionsThe Procedure• First, adipose (fat) tissues are obtained from the hip or abdomen

area.• A unique blend of stem and regenerative cells are separated from

the fat tissue and prepared for injection.• Immediately thereafter, adult stem cells are guided directly into

the damaged joints or delivered intravenously .To address any underlying causes of inflammation, immune response and joint, ligament, bone, muscle or tendon degeneration unique combination of Intravenous and direct injection is used by doctors.

• Stem cells therapy is performed in the specialized clinics using enhanced imaging technology to ensure proper placement of the stem cells.

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Stem cells for orthopedic conditionsConclusion

With the significant progress in the field of stem cells and regenerative medicine, stem cell therapy looks to be an appealing new option but there are many issues which need to be addressed properly prior to the application of these stem cells. For example, how a patient body will react towards the regenerative medicine.

Concerns like safety and efficacy of the treatment along with various other issues like donor-to-donor variation, immunogenicity, etc which need to be addressed. The identification of proper delivery mechanism, dosage, and timing of stem cell therapies for maximum efficacy is also necessary to promote clinical success.

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StemGenn Therapeutics is one of the centre which provide treatment using stem cells for various Orthopedic Diseases.

About StemGenn Therapeutics

• StemGenn Therapeutics is a leading Cell therapy & Regenerative medicine services company that supports the development and commercialization of cellular therapies and stem cell research.

• StemGenn provides cGMP-compliant cell manufacturing and consulting services that address regulatory, financial, technical, process, training and quality system strategies.

• Services include a full spectrum of support and consulting related to process and product development, validation, due diligence evaluations, tissue collection, processing, and storage, product manufacturing, distribution and transportation.


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Why StemGenn Therapeutics ?

• As Stem cell have inherent properties to self renew and differentiation into other cell types. They are multi potent and found within our body.

• No side effects: as it's found in patient's own tissues or blood, chances of rejection and infection is negligible.

• World class clinicians and experts from Regenerative Medicine.

• Cost Effectiveness: autologous stem cell transplant is very much affordable.

• Non- Surgical Procedure & convenient.

• Proven Results.


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The Management & Medical Advisory Board

• Mr. Prabhu Mishra : CEO, Co-Founder

• Ms. Richa Jha : MD, Co-Founder

• Ms. Shreyashi Gangopadhyay: Director- Business Development

• Dr. Sharda Jain : Chairman- Global StemGenn

• Dr. H S Bedi :Director- Cardio Vascular, CMC Ludhiana

• Dr. Satish Totey: Stem Cell Scientist over 35 years Experiences.

• Dr. Roopam Jain: MD Transfusion Medicine, Assoc. Professor.


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StemGenn Therapeutics Services• Stem cell consulting services.

• Stem cell & cord blood bank set up

• Regulatory, financial & compliances consultancy

• Technical & scientific support for Regenerative Medicine

• Stem cell & Bone Marrow Transplant program

• Stem cell Therapy

• Anti ageing program

• Sports Injury and Arthritis : autologous cell implant

• Neuro degenerative diseases & Neuro Rehabilitation & Regenerative Therapy.

• Business Consulting.

• PRP Therapy for Hair Regeneration

• Tissue engineering program for Diabetic foot & Maxillofacial application.

• Dedicated to services of stem cell therapy & Regenerative Medicine( Repair, Regenerate & Restore).


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References

http://stemsd.com/medical-conditions/other-orthopaedic-injuries/http://bramelsecondopinion.com/2012/05/30/navigating-the-nfl-injury-report-orthobiologic-treatments/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270604/

Health & Medicine

Stem Cells for Orthopedic Conditions