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Single-Use Bioreactors for Pharma: World Market 2013-2023

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Contents

1.1 Single-Use Bioreactors: Market Review

1.2 Aims, Scope and Format of the Report

1.3 Research and Analysis Methods

2.1 Introduction

2.1.1 Historical Perspective: A Brief Overview

2.2 The Wave Bioreactor

2.3 Current Single-Use Systems on the Market

2.3.1 Stirred Flexible Disposable Bioreactors

2.3.2 Non-Stirred Flexible Disposable Bioreactors

2.3.3 Stirred Rigid Disposable Bioreactors

2.3.4 Non-Stirred Rigid Disposable Bioreactors

2.3.5 Fixed-Bed Bioreactors

2.4 Construction Material for Single-Use Bioreactors

2.5 Measurement and Control for Single-Use Bioreactors

2.6 Main Applications of Disposable Bioreactors

3.1 The World Single-Use Bioreactors Market in 2012

3.2 Growing Market for Single-Use Bioreactor Systems

3.2.1 Sales Forecast for Overall Single-Use Bioreactors Market, 2012-2017

3.2.2 Sales Forecast for Overall Single-Use Bioreactors Market, 2018-2023

3.3 Breakdown of the Global Single-Use Bioreactors Market

3. The World Market for Single-Use Bioreactors, 2013-2023

2. Single-Use Bioreactor Technologies: an Introduction

1. Executive Summary

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Contents 3.3.1 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2012-2017

3.3.2 Sales Forecast for Single-Use Bioreactors: Hardware Modules/Systems, 2018-2023

3.3.3 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2012-2017

3.3.4 Sales Forecast for Single-Use Bioreactors: Disposables and Accessories, 2018-2023

3.4 Leading National Markets for Single-Use Bioreactors Technology, 2013-2023

3.4.1 The US Market for Single-Use Bioreactors Technology, 2013-2023

3.4.2 The Japanese Single-Use Bioreactors Technology Market, 2013-2023

3.4.3 The Leading European Single-Use Bioreactors Technology Markets, 2013-2023

3.4.4 Emerging National Markets for Single-Use Bioreactor Technology

3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013-2023

3.4.6 The Indian Single-Use Bioreactors Technology Market, 2013-2023

4.1 Introduction

4.2 Xcellerex

4.2.1 Overview

4.2.2 Products, Platforms & Technology

4.2.2.1 FlexFactory Biomanufacturing Platform

4.2.2.2 XDR Single-Use Bioreactors

4.2.2.3 XDM QUAD Single-Use Mixing Systems

4.2.2.4 XDA Disposable Assembly

4.2.2.5 Process Development Services

4.2.2.6 FlexFactory Services

4.2.3 Finances

4.2.4 Xcellerex Milestones & Recent Developments

4.2.5 GreenVax Selects Xcellerex XDR Single-Use Bioreactors for New Vaccine and

Biotherapeutics Programme

4.2.6 Future Outlook and Commercial Strategy

4. Leading Companies in the Market

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Contents 4.2.7 GE Healthcare Completes Acquisition of Xcellerex

4.3 Cellexus Limited

4.3.1 Overview

4.3.2 Global Presence

4.3.3 Products

4.3.4 CellexusBag

4.3.5 CellMaker PLUS

4.3.5.1 CellMaker PLUS Components

4.3.5.2 CellMaker PLUS Dimensions and Specifications

4.3.6 The Cellexus Oxygenator

4.3.6.1 Cellexus Oxygenator: Main Features and Benefits

4.3.6.2 Cellexus Oxygenator Dimensions and Specifications

4.3.7 Single-Use Bioreactor Cell Culture Control Instrumentation

4.3.8 Cellexus Airlift Proprietary Technologies

4.3.9 Single-Use, Non-Penetrative Sensor Technology

4.3.10 Future Outlook

4.4 Sartorius Stedim Biotech

4.4.1 Overview

4.4.2 International Presence

4.4.3 Services and Products

4.4.4 Revenues

4.4.5 Future Outlook

4.5 Thermo Scientific Hyclone

4.5.1 Overview

4.5.2 Global Presence

4.5.3 Thermo Scientific HyClone Products

4.5.4 Thermo Scientific HyClone (SUB): A Disposable Alternative to Conventional Stirred Tank

Bioreactors

4.5.5 Hyclone SUB Components

4.5.6 Future Outlook

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Contents 4.6 GE Healthcare

4.6.1 Overview

4.6.2 Global Presence

4.6.3 Bioreactor Products

4.6.4 WAVE Bioreactor Systems

4.6.5 Cell Culture Products

4.6.6 Mixing Products

4.6.7 Fluid Transfer Products

4.6.8 M&A Activity

4.6.9 Future Outlook

4.7 PBS Biotech

4.7.1 Overview

4.7.2 Global Footprint

4.7.3 PBS Design and Air Wheel Mixing System

4.7.4 Applications & Processes

4.7.5 PBS Specialties

4.7.6 Main Products

4.7.7 Company Highlights

4.7.8 Future Outlook

4.8 ATMI LifeSciences

4.8.1 Overview

4.8.2 Global Footprint

4.8.3 ATMI Specialties

4.8.4 Main Bioreactor Products

4.8.4.1 iCELLis

4.8.4.2 Nucleo Single-Use Bioreactor

4.8.4.3 PadReactor Single-Use Bioreactor

4.8.4.4 Xpansion Bioreactor

4.8.4.5 Bag Conversion

4.8.5 Other Disposable Products

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Contents 4.8.6 Financial Performance

4.8.7 Future Outlook

5.1 Introduction

5.2 Commercial Drivers of the Single-Use Bioreactors Market

5.2.1 Cost Reduction: A Major Driver in Disposable Bioreactors Market

5.2.2 Comparison of Single-Use and Traditional Manufacturing Systems

5.3 Commercial Restraints for the Single-Use Bioreactors Market

5.3.1 Disposable Bioreactors and their Impact on the Environment

5.3.2 Options for Waste Disposal for Bioreactors

5.3.3 Lack of Defined ‘Leachable and Extractable’ Standards Causing Concern

5.3.4 Disposable Bioreactors Unlikely to Replace Traditional Manufacturing Systems Entirely

5.3.5 Scalability and Size Limitations Still Concern Biomanufacturers

5.4 Challenges Facing the Single-Use Bioreactor Technology Industry and Market

5.4.1 Bottlenecks in Downstream Processing

5.5 Summary

6.1 Interview with Mr Christian Julien, Business Development Manager, Meissner Filtration

Products, Inc. Camarillo, California, USA

6.1.1 On Current Market for Single-Use Bioreactors

6.1.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.1.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.1.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.1.5 On Advantages of Disposable Technology

6.1.6 On Major Drawbacks of Single-Use Bioreactor Technology

6. Research Interviews from Our Survey

5. Qualitative Analysis of the Single-Use Bioreactor Technology Market

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Contents 6.1.7 On New Developments in the Single-Use Bioreactors Sector

6.1.8 On Pipeline Technology in the Single-Use Bioreactors Market

6.2 Interview with Dr Karl G. Schick, PhD, Vice President of Research & Development, SciLog

Inc., Madison, Wisconsin, USA

6.2.1 On Current Market for Single-Use Bioreactors

6.2.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.2.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.2.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.2.5 On Advantages of Disposable Technology

6.2.6 On Major Drawbacks of Single-Use Bioreactor Technology

6.2.7 On New Developments in the Single-Use Bioreactors Sector

6.2.8 On Pipeline Technology in the Single-Use Bioreactors Market

6.3 Interview with Professor Pamela J. Weathers, PhD, Biology & Biotechnology Dept.,

Worcester Polytechnic Institute, Worcester, MA, USA

6.3.1 On Current Market for Single-Use Bioreactors

6.3.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.3.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.3.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.3.5 On Advantages of Disposable Technology

6.3.6 On Major Drawbacks of Single-Use Bioreactor Technology

6.3.7 On New Developments in the Single-Use Bioreactors Sector

6.3.8 On Pipeline Technology in the Single-Use Bioreactors Market

6.4 Interview with Professor Milen Georgiev, PhD, Institute of Microbiology, Bulgarian Academy

of Sciences, Plovdiv, Bulgaria

6.4.1 On Current Market for Single-Use Bioreactors

6.4.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.4.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.4.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.4.5 On Advantages of Disposable Technology

6.4.6 On Major Drawbacks of Single-Use Bioreactor Technology

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Contents 6.4.7 On New Developments in the Single-Use Bioreactors Sector

6.5 Interview with James B. Schultz, Vice President, Sales & Marketing, PBS Biotech, Camino

Ranchero, Camarillo, CA, USA

6.5.1 On Current Market for Single-Use Bioreactors

6.5.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.5.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.5.4 On Advantages of Disposable Technology

6.5.5 On Major Drawbacks of Single-Use Bioreactor Technology

6.5.6 On New Developments in the Single-Use Bioreactors Sector

6.5.7 On Technologies in Pipeline for the Single-Use Bioreactors Sector

6.6 Interview with Dr Tibor Anderlei, Head of Science and Business Development, Adolf Kühner,

Dinkelbergstr, Birsfelden, Basel, Switzerland

6.6.1 On Current Market for Single-Use Bioreactors

6.6.2 On Key Unmet Needs in the Market for Single-Use Bioreactors

6.6.3 On R&D and Areas of Focus in Single-Use Bioreactor Technology

6.6.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.6.5 On Advantages of Disposable Technology

6.6.6 On Major Drawbacks of Single-Use Bioreactor Technology

6.6.7 On Technologies in the Pipeline for the Single-Use Bioreactors Sector

6.7 Interview with Dr Jean Paul Ducos, Nestlé R&D Centre Tours, France

6.7.1 On Plant Propagation R&D and Areas of Focus in Single-Use Bioreactor Technology

6.7.2 On Main Challenges in Plant Propagation Research and Single-Use Bioreactor

Technology

6.7.3 On Advantages of Single-Use Bioreactor Technology for Plant Propagation

6.7.4 On Drawbacks of Single-Use Bioreactor Technology in Plant Propagation

6.7.5 On New Developments in Single-Use Bioreactors Sector

6.7.6 On Pipeline Technology in Single-Use Bioreactors Market

6.8 Interview with William Whitford, Sr. Technical Market Manager, Thermo Scientific Cell

Culture & BioProcessing, Thermo Fisher Scientific, Utah, USA

6.8.1 On Current SUB Market

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Contents 6.8.2 On Key Unmet Needs in the Single-Use Bioreactors Market

6.8.3 On Key Areas of Focus in Single-Use Bioreactor Technology

6.8.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.8.5 On Advantages of Disposable Technology

6.8.6 On Major Drawbacks of Single-Use Bioreactor Technology

6.8.7 On R&D and SUB Sector

6.8.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector

6.9 Dr. Gerhard Greller, R&D Director Upstream Technology, Sartorius Stedim Biotech,

Goettingen, Germany

6.9.1 On Current SUB Market

6.9.2 On Key Unmet Needs in the Single-Use Bioreactors Market

6.9.3 On Key Areas of Focus in Single-Use Bioreactor Technology

6.9.4 On Main Challenges Facing the Single-Use Bioreactors Market

6.9.5 On Advantages of Disposable Technology

6.9.6 On Major Drawbacks of Single-Use Bioreactor Technology

6.9.7 On R&D and SUB Sector

6.9.8 On Pipeline Products and Technologies in the Single-Use Bioreactors Sector

6.10 Overview of the Biotech Industry in 2013: Interview with Ronald A. Rader, President of

Biotechnology Information Institute (BII)

6.10.1 Steady Growth, but a Dearth of New Blockbusters

6.10.2 The Price of Biological Drugs

6.10.3 Biosimilars to Outnumber Innovator Products

6.10.4 ‘Differentiated Biologics’: Biosimilars Vs Bio-Betters

6.10.5 Changing of the Guard: Can New Classes of Biopharmaceuticals Transform the

Market?

6.10.6 Big Pharma and the Biotechs

6.10.7 Bundled Payments and Bulked-up Portfolios, and Other Reasons Why Every Major

Player Will Get Involved in Biosimilars

6.10.8 Modular Bioprocessing: The Next Revolution?

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Contents

7.1 Overview

7.2 Prominent Companies in the Market

7.3 Commercial Drivers of the Single-Use Bioreactors Market

7.4 Future Outlook and Concluding Remarks

7. Conclusions: Single-Use Bioreactor Systems – a Growth Market

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Contents

Table 2.1 A Selection of Single-Use Bioreactor Systems on the Market, 2013

Table 3.1 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Table 3.2 World Single-Use Bioreactors Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.3 World Single-Use Bioreactors: Market Hardware Modules/Systems Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017

Table 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023

Table 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017

Table 3.6 World Single-Use Bioreactors Market: Disposables and Accessories Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023

Table 3.7 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017

Table 3.8 Single-Use Bioreactors Submarket Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023

Table 3.9 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Table 3.10 The US Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.11 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Table 3.12 The Japanese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.13 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

List of Tables

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Contents Table 3.14 The EU 5 Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.15 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Table 3.16 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.17 The Indian Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Table 3.18 The Indian Single-Use Bioreactors National Markets Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.19 Single-Use Bioreactors: Leading National Markets Revenue Forecast ($m), AGR (%), CAGR (%), 2012-2017

Table 3.20 Single-Use Bioreactors: Leading National Market Revenue Forecast ($m), AGR (%), CAGR (%), 2018-2023

Table 4.1 Single-Use Bioreactors: Manufacturers and Suppliers, 2013

Table 4.2 CellMaker PLUS Component Dimensions and Specifications, 2013

Table 4.3 Cellexus Oxygenator Dimensions and Specifications, 2013

Table 5.1 SWOT Analysis: Strengths and Weaknesses of the World Single-Use Bioreactors Market, 2013-2023

Table 5.2 SWOT Analysis: Opportunities and Threats in the World Single-Use Bioreactors Market, 2013-2023

Table 5.3 Comparison of Disposal Options for Single-Use Bioreactor System, 2013

Table 7.1 Single-Use Bioreactors Market: World Revenue Forecast ($m), AGR (%), CAGR (%) by Sector in 2012, 2014, 2017, 2020 and 2023

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Contents

Figure 2.1 Main Applications and Classes of Disposable Bioreactors, 2013

Figure 3.1 World Single-Use Bioreactors Market Revenue Forecast ($m), 2012-2017

Figure 3.2 World Single-Use Bioreactors Market Revenue Forecast ($m), 2018-2023

Figure 3.3 World Single-Use Bioreactors Market: Hardware Modules/ Systems Revenue ($m)

Forecast, 2012-2017

Figure 3.4 World Single-Use Bioreactors Market: Hardware Modules/Systems Revenue ($m)

Forecast, 2018-2023

Figure 3.5 World Single-Use Bioreactors Market: Disposables and Accessories Revenue ($m)

Forecast, 2012-2017

Figure 3.6 World Single-Use Bioreactors Market: Disposables & Accessories Revenue ($m)

Forecast, 2018-2023

Figure 3.7 Single-Use Bioreactors: Submarket Revenue ($m) Forecasts, 2012-2023

Figure 3.8 The US Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023

Figure 3.9 Japan: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023

Figure 3.10 EU 5 Countries: Single-Use Bioreactors National Market Revenue ($m) Forecasts,

2012-2023

Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023

Figure 3.12 India: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023

Figure 3.13 US, Japan and Total Worldwide Single-Use Bioreactors Markets: Revenue ($m)

Forecasts, 2012-2023

Figure 3.14 EU 5 and Other Leading Single-Use Bioreactors National Markets: Revenue ($m)

Forecasts, 2012-2023

Figure 3.15 Single-Use Bioreactors: National Market Revenue Shares (%), 2012

Figure 3.16 Single-Use Bioreactors: National Market Revenue Shares (%), 2017

Figure 3.17 Single-Use Bioreactors: National Market Revenue Shares (%), 2020

Figure 3.18 Single-Use Bioreactors: National Market Revenue Shares (%), 2023

Figure 4.1 Xcellerex: Opportunities and Threats, 2013-2023

Figure 4.2 Cellexus: Opportunities and Threats, 2013-2023

List of Figures

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Contents Figure 4.3 Sartorius Stedim Biotech: Opportunities and Threats, 2013-2023

Figure 4.4 Thermo Scientific Hyclone: Opportunities and Threats, 2013-2023

Figure 4.5 GE Healthcare: Opportunities and Threats, 2013-2023

Figure 4.6 PBS Biotech: Opportunities and Threats, 2013-2023

Figure 4.7 ATMI: Opportunities and Threats, 2013-2023

Figure 5.1 Estimated Cost Savings of Single-Use Bioreactors in Comparison with Stainless Steel

Systems, 2013

Figure 5.2 Disposal Route Taken by Companies for Single-Use Plastic Materials, 2009

Figure 7.1 The Single-Use Bioreactors Market: Market Shares (%) in The Worldwide Single-Use

Systems Market, 2012

Figure 7.2 Single-Use Bioreactors Market: World Revenue Forecast ($m) by Segment in 2012,

2014, 2017, 2020 and 2023

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Contents

3M Occupational Health & Environmental Safety

A Daigger & Company

ABEC

Adolf Kühner

Aeronex

Air Products and Chemicals

Alconox

American Health & Safety

American Instrument Exchange

Amgen

AmProtein

Anachemia Science

Applikon Biotechnology

Artelis

Artisan Industries Inc.

Ashland Chemical Co.

ATL (Ad Tape & Label)

ATMI

Bayer Technology

Bel-Art Products

Bellco Glass

Bioengineering AG

BioProcess Systems Alliance (BPSA)

Bio-Recovery

Biotechnology Information Institute (BII)

Bosch Packaging Technology

Broadley-James

Cambridge Scientific Products

Organisations Mentioned in This Report

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Contents Camile Products

Carolina Biological Supply

CEA Instruments

Cellexus

CELLution Biotech

Chemap

Colder Products Company

Columbus Instruments International

CPG

CRC Press

Curtin Matheson Scientific

Dan Kar Corporation

Dynalon Products

Eagle Manufacturing Company

EMA (EU)

Eppendorf

ExcellGene

FDA (US)

Finesse

G&G Technologies

G-Con

GE Healthcare

Gerresheimer

Glastron /Tech Glass

GoIndustry DoveBid

Guthrie Medicare Products

HEMCO Corporation

Hydrite Chemical Co.

Immunetics

Institute of Microbiology, Bulgarian Academy of Sciences, Plovdiv, Bulgaria

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Contents INTEGRA Biosciences - Viaflo Corporation

InVitro International

Jencons Scientific

Kimble/Kontes (A company of The Gerresheimer Group)

Kleiner Perkins Caufield & Byers

Kuhner

Lab-Line Instruments

Laboratory Disposable Products

Labsystems

Lonza

Markson LabSales

Materia Medica

Matrix Technologies Corporation

Meissner Filtration Products

Membrana

Merck & Co.

MHLW (Japan)

MIDSCI

Millipore

mp2-labs

Nestlé

New Brunswick Scientific

New England Glove Company

Nilfisk Industrial Vacuums

Nova Biomedical

Omni International

Pall Life Sciences - BioPharmaceuticals

PBS Biotech

Pegasus Scientific

Pierre Guerin

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Contents Poly-Pipets

Pope Scientific

Precision Weighing Balances

Presens

Qosina Corporation

QPS Medical Disposable Products

Recycle & Reuse Industries

Sartorius Stedim Biotech

SCG Capital

Schleicher & Schuell

Scientific Adsorbents

SciLog

Siemens Industry- Water Technologies

Sigma Chemical Company

SmartFlow Technologies

Spectrum Chemicals & Laboratory Products

Spectrum Laboratories

Synthecon Incorporated

Texas A&M University

The Chemical Company

The Lee Company

Thermo Fisher Scientific

Thermo Scientific Nalgene and Nunc

Thomas Scientific

Unisyn Medical Technologies

United Laboratory Plastics

USA Scientific

VantagePoint Venture Partners

Veolia Water Solutions & Technologies

VirTis (an SP Industries Brand)

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Contents VWR International

WAVE Biotech

Westfalia Separator

Wheaton Science Products

Worcester Polytechnic Institute, Worcester, MA, USA

Xcellerex

Page 47

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Single-Use Bioreactors for Pharma: World Market 2013-2023

Growth in those markets will be driven by increasing uptake of biotherapeutic agents using single-

use bioreactor technologies. By 2023, the combined revenues of the German, UK, French, Italian

and Spanish markets will be $26.8m, achieving a CAGR of 5.8% for the period 2012 to 2023.

Higher growth rates still are expected in eastern European markets, owing to rapid economic

growth in these countries, with rising demand for vaccines and other biologic agents.

3.4.4 Emerging National Markets for Single-Use Bioreactor Technology The market for single-use bioreactors technology systems is growing rapidly in developing

countries, where rising standards of living and rapid growth in numbers of elderly people are

increasing the demand for biologic pharmaceuticals, with cancer being an important treatment

area. In 2012, the leading emerging-economy markets for single-use bioreactors were those of

China ($2.9m) and India ($0.6m), with combined other markets group generating revenues of

$1.6m (Table 3.19). During the forecast period, 2012 to 2023, the Chinese and Indian pharma

industries will be among the most rapidly growing in the world. This growth will benefit the single-

use bioreactors industry and market.

3.4.5 The Chinese Single-Use Bioreactors Technology Market, 2013-2023 The Chinese single-use bioreactors technology market was worth an estimated $2.9m in 2012, a

5.5% share of the world market. The Chinese pharmaceutical market is expanding rapidly, driven

by that country's rapid economic development, the rise of personal incomes and improvements in

the country's medical system, especially wider healthcare coverage. Western medicines are

becoming widely accepted in China, and there is also a shift to western-style diets and lifestyles,

which is likely to be responsible for an increasing demand for pharmaceutical products (including

biologic drugs and vaccines).

As a result, the total Chinese market for single-use bioreactor technologies will grow rapidly from

2012 to 2023. Growth will be highest from 2012 to 2017. By 2017, the market will be worth $5.6m,

with a CAGR of 14.1% from 2012 to 2017 (Tables 3.15-3.16 and Figures 3.11 and 3.15-3.18). After

2017, growth will slow, as the Chinese economy stabilises after a period of rapid growth. By 2023,

its single-use bioreactors market will have reached $8.0m, representing a CAGR of 9.8% from

2012 to 2023.

Page 48

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Single-Use Bioreactors for Pharma: World Market 2013-2023

Table 3.16 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2018-2023

Table 3.15 The Chinese Single-Use Bioreactors National Market Forecast: Revenues ($m), AGR (%), CAGR (%), 2012-2017

Source: visiongain 2013; CAGR values are for 2012-2017

Source: visiongain 2013; CAGR values are for 2018-2023

Year 2012 2013 2014 2015 2016 2017

China ($m) 2.9 3.5 4.0 4.5 5.0 5.6Annual Growth (%) 22.3 14.5 12.7 10.3 11.1

CAGR (%) 14.1

Year 2018 2019 2020 2021 2022 2023

China ($m) 6.0 6.5 6.9 7.3 7.6 8.0Annual Growth (%) 8.8 7.4 6.4 5.2 5.1 5.0

CAGR (%) 5.8

Figure 3.11 China: Single-Use Bioreactors National Market Revenue ($m) Forecast, 2012-2023

Source: visiongain 2013

2.9

3.5

4.0

4.5

5.0

5.6

6.0

6.5

6.9

7.3

7.6

8.0

0.0

1.0

2.0

3.0

4.0

5.0

6.0

7.0

8.0

9.0

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023

Sale

s ($

m)

Year

China