Rice bran domiatta presentation 1

By

Dr. Amr M. Helal

Health Tech for Integrated Health Solutions

2015 20

Dream or Reality

Before we startsNumbers Never Lies

List of exporters for the selected product in 2013 Product : 1211 Medicinal plants

Value exported in 2013

(USD thousand) Trade balance in 2013 (USD thousand)

World 3,399,350

China 1,196,725

India 207,758

Canada 184,930

United States of

America 168,286

Germany 148,372

Egypt 109,845

Korea, Republic of 109,379

List of exporters for the selected product in 2013 Product : 30 Pharmaceutical products

Trade Indicators

Value exported in 2013 (USD

thousand) Trade balance in 2013 (USD thousand)

World 486,308,192

Germany 73,779,288

Israel 6,099,722

Best Investment !

Percentage of stunted under-fives children (2008 2013)Source: UNICEF/WHO/World Bank Joint Child Malnutrition Estimates, 2014

Egypt is among the 36 high-burden countries Stunting affects approx. 1/3 of under-fives in the developing world

Malnutrition contributes to 1/2 of all deaths in children under 5

Stunting Prevalence in EgyptMCHIP Egypt SMART Project

Rice Bran in EGYPT

Total Rice Cultivated area in Egypt is more than 1.5 Million Acers annually, giving more than 500 000 MT rice bran

Rice Bran is considered as one of the most nutritive ingredients of the rice crop, where about 60% of the total nutritive value of rice itself resides.

Rice BranPROTEINS

OIL DIETARY FIBRE VITAMINS & MINERALS

GAMMA ORYZANOL

ANTIOXIDANTS

TRACE ELEMENTS

RICE BRAN

These components can be obtained from other sources of nature separately, but Rice Bran is unique in having all these constituents together.

Rice Bran Vs Wheat Branhttp://www.healthaliciousness.com/nutritionfacts/nutrition-comparison.php?o=20034&t=20060&h=20077&s= 219.00&e=118.00&r=58.00

Nutrition Facts

Rice bran crude

Serving Size 58g

Calories 186.5

% Daily Value*

Total Fat 12.3g 19%

Saturated Fat

2.5g12.5%

Cholesterol 0mag 0%

Sodium 6mg 0%

Total Carbohydrate

29.3g10%

Dietary Fiber

12.4g50%

Sugar 1.1g ~

Protein 7.9g ~

Nutrition Facts

Wheat bran crude

Serving Size 58g

Calories 125

% Daily Value*

Total Fat 2.47g 4%

Saturated Fat 0.365g 2%

Cholesterol 0mg 0%

Sodium 1mg 0%

Total Carbohydrate

37.4g12%

Dietary Fiber 24.8g 99%

Sugar 0.2g ~

Protein 9g

http://www.healthaliciousness.com/nutritionfacts/nutrition-comparison.php?o=20034&t=20060&h=20077&s

Rice Bran Vs Wheat BranMinerals %DV

Calcium 33.63mg 3.5%

Iron 10.94mg 61%

Magnesium 460.79mg 115%

Phosphorus 989.43mg 99%

Sodium 3mg 0%

Potassium 876.15mg 25%

Zinc 3.56mg 24%

Minerals %DV

Calcium 42.34mg 4%

Iron 6.13mg 34%

Magnesium 354.38mg 89%

Phosphorus 587.54mg 59%

Sodium 1mg 0%

Potassium 685.56mg 20%

Zinc 4.22mg 28%

Rice Bran Fatty Acids

Omega 3 to Omega 6 Ratio 0.04


Total Omega 3s 186.5mg

18D3 Linolenic 186mg

Total Omega 6s 4216mg

18D2 4216mg

Wheat Bran Fatty Acids



Total Omega 3s 97mg

18D3 Linolenic 97mg

Total Omega 6s 1183mg

18D2 1183mg

Rice Bran Nutraceutical / Functional Food Values

Potent Antioxidant

High Nutritional Value

Blood Pressure

Blood Cholesterol

POTENTIAL BENEFITS OF RICE BRAN

Blood Sugar

The process that produces brown rice removes only the outermost layer, the hull, of the rice kernel and is the least damaging to its nutritional value.

The complete milling and polishing that converts brown rice into white rice destroys 67% of the vitamin B3, 80% of the vitamin B1, 90% of the vitamin B6, half of the manganese, half of the phosphorus, 60% of the iron, and all of the dietary fiber and essential fatty acids.

Fully milled and polished white rice is required to be "enriched" with vitamins B1, B3 and iron

WHY NOT white rice

Rich in Fiber and Selenium

ManganeseEnergy Production Plus AntioxidantProtection

Women Who Eat Whole Grains Weigh Less

Lower Cholesterol with Whole Brown Rice

Significant Cardiovascular Benefits for Postmenopausal Women

Phytonutrients with Health-Promoting Activity Equal to or Even Higher than that of Vegetables and Fruits

WHY YES Bran rice Adding Stabilized Bran to Rice

http://www.whfoods.com/genpage.php?tname=foodspice&dbid=128

Lignans Protect against Heart Disease

Reduce Your Risk of Metabolic Syndrome

Brown Rice and Other Whole Grains Substantially Lower Type 2 Diabetes Risk

Fiber from Whole Grains and Fruit Protective against Breast Cancer

Help Prevent Gallstones

Whole Grains and Fish Highly Protective against Childhood Asthma

WHY YES Bran rice Adding Stabilized Bran to Rice

http://www.whfoods.com/genpage.php?tname=foodspice&dbid=128

Recommendation

Add Stabilized Bran to White Rice &Enjoy the taste & health benefit of BRAN RICE !!

However due to non stabilization of Rice Bran; it is still discarded or used as animal feed despite its high content of bioactive substances.

It All Starts with: RICE BRAN INNOVATIVE STABILIZATION

Rice bran was studied (projects cost more thanLE 5 M) where great part of its UNTOLD WEALTHof vitamins, minerals, bioactives were revealedand published.

These provide evidence for its potential healthactivity for alleviation of major illness symptoms;(CVD, DM type II, elevated Cholesterol levels,Anti inflammatory & Hypertension) and recently(2014) increasing brain cells mitochondrial mass.

Research Projects for Rice Bran By Health Tech *

Business Scope; R&D Research Partners:1. Faculty of Pharmacy Cairo University, Egypt 2. National Research Centre, Egypt3. Faculty of Pharmacy, Goethe University,

Frankfurt, Germany 4. Wageningen University (Algae Park), Holland5. Ainia Centro Tecnologica, Spain 6. BasPharma, The Netherlands7. VivaCell Biotechnology GmbH, Germany8. International Trade and Marketing*

(Projects coordinator and HT founder)

Project Name Funding Authority Budget

Rice Bran Stabilization Unit (5-7-1) Faculty of Agriculture, Mansoura University2007-2008

Industrial Modernization Centre (IMC)

70,000 L.E.

Rice Bran Stabilization IndustrialUnit (1-12-53) Faculty of Agriculture, Mansoura University2007-2008


700,000 L.E.

Rice Bran Phytochemical Study (3-7-4)National Research Centre 2008-2009


100,000 L.E.

Rice Bran Industry Implementation (5-7-2)National Research Centre


200,000 L.E.

Project Name Funding Authority

Budget

Developing Rice Bran Nutraceuticals(MED/2008/214-423) Faculty of Pharmacy Cairo

University, Egypt Faculty of Pharmacy Goethe

University VivaCell Biotechnology GmbH,

Germany Faculty of Pharmacy, GUC,

Egypt 2009-2011

Research Development & Innovation Fund (RDI)

EURO 192,500

Project Name Funding Authority

Budget

Ultrasonic Extraction with Spray Drying of Rice Bran Extract (RDI2/S2/26) Faculty of Pharmacy Cairo

University Analyze & Realize, Germany BasPharma, The Netherlands

Research Development & Innovation Fund (RDI)

EURO 104,000

Current Projects

PorridgePlus - a food against dementia

The aim of the project is to develop a food product for elderly with the objective to promote healthy brain aging.

BackgroundRice bran is especially rich in bioactivecomponents showing significant biologicaleffects, such as anti-inflammatory,cholesterol-lowering, antioxidant and anti-diabetic activity. Key components areoryzanols (a mixture of ferulic acid esters oftriterpene alcohol and sterol), tocopherolsand tocotrienols.

AIMThe aim of the project is to develop a food product for elderly with the objective to promote healthy brain aging. The basis for the project are findings that Rice Bran Extract protects from mitochondrial dysfunction in the brain.Together with partners from Egypt, the aim of our studies is the establishment of rice bran extract as potential food supplement to prevent neurodegeneration

Rice bran extract protects from mitochondrial dysfunction in guinea pig brains.Hagl S1, Kocher A, Schiborr C, Eckert SH, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Muller WE, Eckert GP.Pharmacol Res. 2013 Oct;76:17-27. doi: 10.1016/j.phrs.2013.06.008. Epub2013 Jul 1.Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer's disease.Hagl S1, Grewal R1, Ciobanu I1, Helal A2, Khayyal MT3, Muller WE1, Eckert GP1.J Alzheimers Dis. 2015;43(3):927-38. doi: 10.3233/JAD-132084.GP.Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI miceHagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert Nutr Neurosci, 2015, accepted

http://www.ncbi.nlm.nih.gov/pubmed/?term=Hagl S[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Kocher A[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Schiborr C[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Eckert SH[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Ciobanu I[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Birringer M[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=El-Askary H[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Helal A[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Khayyal MT[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Frank J[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Muller WE[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Eckert GP[Author]&cauthor=true&cauthor_uid=23827162http://www.ncbi.nlm.nih.gov/pubmed/23827162http://www.ncbi.nlm.nih.gov/pubmed/?term=Hagl S[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Grewal R[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Ciobanu I[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Helal A[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Khayyal MT[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Muller WE[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/?term=Eckert GP[Author]&cauthor=true&cauthor_uid=25125472http://www.ncbi.nlm.nih.gov/pubmed/25125472

Healthtech- BASPHARMA INNOVATIONSFunctional Beverages

VITAFOOD EU 2105 Swiss

Project Outputs Marketing

Products registrationORYZA

Stabilized Rice Bran Sachets

Registration at the Egyptian Ministry of Health

INNOVATION AWARDS

National and Intl MEDIA COVERAGE

Nations s Wealth

Is not by what they have

Or what they know

But

By Knowing what to do

with what they have

Health & Medicine

Rice bran domiatta presentation 1