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Prepared & Presented by: Muhammad Haroon, Muhammad Hassaan Khalid & Rao Jahanzaib from MBBS class of 2017.
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Group Members
1)Muhammad Haroon240
2)Muhammad Hassaan Khalid 241
3)Rao Jahanzaib242
Referred pain
Referred pain
Definition
Physiological Basis/ Mechanism
Different Examples
Importance
Definition
pain perceived at a location other than the site of the painful stimulus.
Irritation of a visceral organ frequently produces pain that is felt not at that site but in some somatic structure that may be a considerable distance away. Such pain is said to be referred to the somatic structure.
also called reflective pain
Referred pain mechanism
2 mechanisms Dermatomal rule
Convergence–projection theory
Referred pain mechanism
(Dermatomal rule)
Dermatomal rule- When pain is referred, it is usually to a structure that developed from the same embryonic segment or dermatome as the structure in which the pain originates. This principle is called dermatomal rule
FOR INSTANCE: the heart and the inner aspect of left arm
Testicle & ureter+kidney(from urogenital ridge)
Referred pain mechanism(Convergence– projection
theory)
Convergence– projection theory Second mechanism for referred pain may be convergence
of somatic and visceral pain fibers on the same second-order neurons in the dorsal horn that project to the thalamus and then to the somatosensory cortex (Figure 10–3). This is called the convergence– projection theory.
Referred pain mechanism(Convergence– projection
theory)
Somatic and visceral neurons converge in lamina I–VI of the ipsilateral dorsal horn
Neurons in lamina VII receive afferents from both sides of the body
explains referral of pain to the side opposite that of the source of pain i. e. affected organ.
Convergence– projection theory
Convergence– projection theory
Convergence– projection theory
If prolongation of visceral stimulus
facilitation of the somatic fiber endings
stimulate the second order neurons
brain interprets activity in a pathway as arising from somatic sources
Referred pain in somatic area
The somatic nociceptive fibers normally do not activate the second-order neurons. But……..
Note
However, sites of referred pain are not stereotyped, and unusual reference sites occur with considerable frequency.
FOR INSTANCE
Cardiac pain, for instance, is usually referred to Upper chest/left limb But it may be referred to the right arm, the abdominal region, or even the back and neck.
..........
Visceral Pain
Pain from the different viscera of the abdomen and chest .
transmitted through small type C pain fibers
Causes of True Visceral Pain :
1. Ischemia
2. Chemical Stimuli
3. Spasm of a Hollow Viscus
4. Overdistention of a Hollow Viscus
Localization of Visceral Pain
Pain from the different viscera is frequently difficult to localize because :
1. patient’s brain does not know from firsthand experience that the different internal organs exist.
2. sensations from the abdomen and thorax are transmitted through two pathways to the central nervous system—the true visceral pathway and the parietal pathway.
True visceral pain is transmitted via pain sensory fibers within the autonomic nerve bundles, and the sensations are referred to surface areas of the body often far from the painful organ.
parietal sensations are conducted directly into local spinal nerves from the parietal peritoneum, pleura, or pericardium, and these sensations are usually localized directly over the painful area.
Localization of Referred Pain Transmitted via Visceral Pathways.
person generally localizes visceral in the dermatomal segment from which the visceral organ originated in the embryo.
Pain from the viscera is frequently localized to two surface areas of the body at the same time because of the dual transmission of pain through the referred visceral pathway and the direct parietal pathway.
Examples
Upper chest/left limb
o Myocardial ischaemia
Right tip of scapula
o Liver, gallbladder
Left shoulder
o Thoracic diaphragm, Spleen (Kehr's sign, lung
Back
o Pancreas
Umblicus
o Small intestine ;appendex
Importance
Knowledge of the different types of referred pain is important in clinical diagnosis because in many visceral ailments the only clinical sign is referred pain.