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S . VENKATESH

Nano carriers in cancer treatment

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Page 1: Nano carriers in cancer treatment

S . VENKATESH

Page 2: Nano carriers in cancer treatment

INTRODUCTIONA nanocarrier is nanomaterial being used as a transport

module for another substance, such as a drug.

Commonly used nanocarriers include micelles, polymers, carbon-based materials, liposomes and other substances.

Nanocarriers are currently being studied for their use in drug delivery and their unique characteristics demonstrate potential use in chemotherapy.

UPAC definition

Particle of any shape with dimensions in the 1 × 10−9 and 1 × 10−7 m range.

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ORIGINAlthough, in general, nanoparticles are

considered a discovery of modern science, they actually have a long history.

Nanoparticles were used by artisans as far back as the ninth century in Mesopotamia for generating a glittering effect on the surface of pots.

Michael Faraday provided the first description, in scientific terms, of the optical properties of nanometer-scale metals in his classic 1857 paper.

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TYPES OF NANO CARRIERS

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RATIONAL USE OF NANO CARRIRERS

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MECHANISM

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EXAMPLES OF NANO BASED PLATFORMS AND THEIR CURRENT STAGE OF DEVELOPMENT FOR THE USE IN CANCER THERAPY

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CONCLUSION The clinical success of various nano carrier

constructs in cancer therapy have made these and similar systems promising drug delivery vehicles for future work aimed to further improve their overall drug delivery efficacy . for example, the clinical success based on passively delivering chemotherapeutics encapsulated within both liposomes and micelles in cancer treatment have made these nano carriers particularly attractive candidates for future work involving a more active form of delivery

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REFERENCES 1.)https://en.wikipedia.org/wiki/Nanocarriers

2.) Nanocarriers in modern drug delivery systems Katarzyna NIEMIROWICZ, Halina CAR – Department of Experimental Pharmacology, Medical University of Bialystok, Białyst, CHEMIK 2012, 66, 8, 868-881

3.)Dan Peer1†, Jeffrey M. Karp2,3†,Seungpyo Hong4†, Omid C. Farokhzad5,Rimona Margalit6 and Robert Langer3,4*1Immune Disease Institute and Department of Anesthesia, Harvard MedicalSchool, Boston, Massachusetts 02115, USA; 2HST Center for BiomedicalEngineering, Department of Medicine, Brigham and Women’s Hospital, HarvardMedical School, Cambridge, Massachusetts 02139, USA; 3Harvard-MIT Divisionof Health Sciences and Technology, Massachusetts Institute of Technology,Cambridge, Massachusetts 02139, USA; 4Department of Chemical Engineering,Massachusetts Institute of Technology, Cambridge, Massachusetts 02139,USA; 5Laboratory of Nanomedicine and Biomaterials and Department ofAnesthesiology, Brigham and Women’s Hospital, Harvard Medical School,Boston, Massachusetts 02115, USA; 6Department of Biochemistry, GeorgeS. Wise Faculty of Life Sciences, and the Center for Nanoscience and Nanotechnology, Tel Aviv University, Tel Aviv, 69978, Israel, Nanocarriers as an emerging platform for cancer therapy

4.)http://ec.europa.eu/health/scientific_committees/opinions_layman/en/nanotechnologies/l-3/4-nanoparticle-formation.htm

5.)https://en.wikipedia.org/wiki/Nanoparticle

6.)https://en.wikipedia.org/wiki/Nanoparticle

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