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CHAPTER ONE
ABNORMAL PREGNANCY
BY GEBREMARYA TEMESGEN BSC MW 1
MINOR DISOEDERS OF PREGNANCY
BY GEBREMARYA TEMESGEN BSC MW2
Minor Disorders of Pregnancy
• Are only minor and are not life threatening
• But may escalate and becomes serious. complications of pregnancy( e.g. hyperemisis gravidarum can arise from morning sickness).
Causes of minor disorders can be divided in to:
1. Hormonal changes: e.g. Nausea & vomiting
2. Accommodation change: e.g. frequency of micturition
BY GEBREMARYAM TEMESGEN BSC MW 3
Minor cont..
3. Metabolic changes: e.g. pica and
4. Postural changes: e.g. back ache
Note: Every system of the body adjusts and is affected by pregnancy
A. Digestive System
1. Nausea & Vomiting (Morning Sickness)
– Complicates about 70% of all pregnancies.
– Present b/n 4th and 16th week of pregnancy
BY GEBREMARYA TEMESGEN BSC MW4
Minor cont…
- Associated with high level of human chorionic gonaodotropin hormone (hCG), estrogen and progestron.
- Not confined to early morning, can occur at any time in the day
- Can persist and become hyperemisis gravidarum.
NB: Beware to rule out other causes of vomiting e.g. appendicitis.
BY GEBREMARYA TEMESGEN BSC MW5
Minor cont…
Treatment of Nausea & Vomiting
• Reassure the mother that the symptoms will soon settle.
• Advise to eat small and frequent meals and to avoid fatty foods.
• Advise to eat dry foods before getting out of bed. E.g. ‘Kollo’
• Avoid liquid with meals.
• Rise slowly from lying or sitting.
BY GEBREMARYA TEMESGEN BSC MW6
Minor cont…
2. Heart Burn
Is a burning sensation in the mediastianal region resulted from:
• Relaxation to smooth GI muscles and cardiac sphincter of the stomach allowing gastric reflux of stomach contents to the lower esophagus.
• Displacement of stomach and duodenum by enlarging uterus (30 – 40 weeks)
BY GEBREMARYA TEMESGEN BSC MW7
Minor cont…
Treatment of Heart burn
• If the heart burn is occasional advise the woman to:– Avoid bending over while house keeping
– Avoid kneeling to clean the bath
– Eat small and frequent meals
– Seep with extra pillows
– Avoid fried or spicy foods
– Avoid citrus fruits
BY GEBREMARYA TEMESGEN BSC MW8
Minor cont…
Treatment of Heart burn cont..• If the heart burn is persistent:
– The above advise plus anti acids e.g. MTS(Magnesium trisilicate). Do not give Al2(OH) as it can cause or exacerbate constipation.
3. ConstipationCause: Relaxed gut smooth muscles due to the
effect of the hormone progesterone decreased peristalsis delay in emptying much water is re absorbed constipation.
Oral iron can exacerbate
BY GEBREMARYA TEMESGEN BSC MW9
Minor cont…
Treatment of constipation
• Increase intake of water(6 – 8 glasses per day)
• High residue diet(fresh vegetables)
• A glass of warm water in the morning
• Exercise. E.g. walking
NB: Constipation can aggravate hemorrhoids
BY GEBREMARYA TEMESGEN BSC MW10
Minor cont…
4. Excessive Salivation (Ptyilsm)
Cause: Difficulty in swallowing caused by the nausea and not because of the excess production of saliva
• Occurs from 8 weeks
Treatment:
- Practice good oral hygiene - Suck hard candy
- Avoid excessive starch intake
- Eat Kollo
BY GEBREMARYA TEMESGEN BSC MW11
Minor cont…
5. Pica:
Is a persistent carving and compulsive consumption of substances such as coal, soup, or clay etc.
Causes: Many theories
1. Nutritional deficiency
2. Cultural
Rx: Advise the mother that the act can harm her and her fetus( electrolyte imbalance, metabolic disturbance may occur)
BY GEBREMARYA TEMESGEN BSC MW12
Minor cont…
6. Gingivitis
Cause:
Hypertrophy of gums due to estrogen effect
Rx:
• Tooth brush
• Oral hygiene
• Reassurance
BY GEBREMARYA TEMESGEN BSC MW13
Minor Cont…
7. Hemorrhoids
Cause: Progesterone related
Treatment: Avoid constipation
B. Musculoskeletal System
1. Back ache
Cause: Softened ligaments due to progesterone and relaxin effect.
BY GEBREMARYA TEMESGEN BSC MW 14
Minor cont…
Treatment of back ache
• Correction of posture( advise to sleep on a firm mattress and sit on upright chair).
• Avoid high heeled shoes.
• Use leg muscle while lifting objects.
• Avoid lifting heavy objects.
• Reassurance and rest.
NB: Rule out UTI and onset of labour.
BY GEBREMARYA TEMESGEN BSC MW15
Minor Cont…
2. Leg Cramps:
Cause: Unknown may be de to change in PH
Management: Advise the mother to:
• Raise the foot of the bed about 25 cm.
• Keep legs warm.
• Get regular exercise, walking.
• Stand on the affected leg to strengthen muscles.
BY GEBREMARYA TEMESGEN BSC MW16
Minor Cont….
C. Genitourinary System
1. Frequency of maturation:
• Occurs early pregnancy from 6 – 12 weeks and in late pregnancy after lightening has occurred.
Cause: Pressure on the urinary bladder from the growing utters or fetal head.
Rx: Reassure the woman
NB: exclude other causes. E.g. UTI.
BY GEBREMARYA TEMESGEN BSC MW17
Minor Cont…
Genitourinary cont..2. Leucorrhoea: This is a term used to describe increased,
white, non offensive, non itchy vaginal discharge in pregnancy.
Cause: Desquamation of the superficial cells of the vagina.
Rx: -Reassurance- Personal hygiene, washing with plain water 2x per
day. Do not use soap.- Cotton underwear , avoiding tights, exclude other
causes.
BY GEBREMARYA TEMESGEN BSC MW18
Minor Cont…
D. Circulatory System1. FaintingCause: i. In early pregnancy: Vasodilatation before the
compensatory increase in blood volumeii. In late pregnancy: laying flat on back( Supine
hypotensive syndrome)Rx: - Avoid long period of standing
-Avoid laying on back except during abdominal exam
BY GEBREMARYA TEMESGEN BSC MW19
Minor cont…
1. Management of fainting cont…
- Turn the mother quickly to the left lateral side when she feels faint during abdominal examination.
- Avoid sudden change in position.
BY GEBREMARYA TEMESGEN BSC MW 20
Minor Cont…
Circulatory cont…
2. Varicosities:
Cause:
• Progesterone relaxes the smooth muscles of the veins and results in sluggish circulation.
• The valves of the dilated veils becomes inefficient + pressure from the gravid uterus and results in varicosities.
BY GEBREMARYA TEMESGEN BSC MW21
Minor Cont…
Usual sites of Varicose vein:
• Legs
• Anus (Hemorrhoids)
• Vulva
- Hemorrhoids can be complicated by constipation
- Woman with family history of varicose vein, and those doing work which demands long period of standing or sitting are at high risk to develop varicosities.
BY GEBREMARYA TEMESGEN BSC MW22
Minor Cont…
Management of Varicosities:
• Avoid long period of standing
• Elevate legs when sitting
• Wear support tights or stockings
• Avoid sitting on the edge of the bed or chair
• Hospital delivery for vulval and hemorrhoids.
BY GEBREMARYA TEMESGEN BSC MW23
Minor Cont…
• E. Intrigumentary System
1. Skin Changes
– Linea nigra
– Chloasma
– Areola
Management
- Reassure the mother that they are signs of pregnancy and settle soon after delivery
BY GEBREMARYA TEMESGEN BSC MW24
Minor Cont…
Intrigumentary cont…
2. Itching of the skin
• Often starts over the abdomen
• May be due to the liver hormones responding to pregnancy hormones
• Clear as soon as the baby born
Rx: Antihistamines e.g. chloropheniramine.
For vulval itching R/O candidiasis
BY GEBREMARYA TEMESGEN BSC MW25
Minor cont..
F. Nervous System
1. Carpal tunnel Syndrome/CTS/
• Is a sensation of numbness and pins’ and needles’ in the fingers and hands.
Cause: Pregnancy hormone(progestron) fluid retention edema pressure on the median nerve numbness.
BY GEBREMARYA TEMESGEN BSC MW 26
Minor Cont…
Management of CTS
1. Anti pain
2. Wearing of split at night with hands resting high on two or three pillows may bring relief.
3. Diuretics may e needed
It usually resolves spontaneously following delivery.
BY GEBREMARYA TEMESGEN BSC MW 27
Minor Cont…
CNS Cont..2. Insomnia(Sleeplessness) Causes:A. Physical Reasons
– Nocturnal frequency– Difficulty in getting comfortable in bed b/s of the
growing uterus
B. Psychological reasons: AnxietyC. Hormonal reasons: May contribute to
depression
BY GEBREMARYA TEMESGEN BSC MW28
Minor Cont..
Management of Insomnia
• Never dismiss lightly
• Ask what she has been dreaming and discuss and reassure
• Small pillow under the abdomen and lying in the lateral position
• Consider psychiatric unit if it seems ‘abnormal’
BY GEBREMARYA TEMESGEN BSC MW29
Hyperemesis gravidarum (HEG)
30BY GEBREMARYA TEMESGEN BSC MW
Hyperemisis gravidarum
• Hyper emesis gravidarum
Definition: Vomiting that starts before 20th
week of pregnancy, severe enough to cause electrolyte, metabolic and nutritional imbalance in known as hyperemisis gravidarum
• It is a rare case but can cause
– Dehydration
– Electrolyte imbalance
– Keto - acidosis
– Weight loss. 31
BY GEBREMARYA TEMESGEN BSC MW
HEG Cont..
Incidence:1 in 1000 pregnant women.
Causes:• The cause is unknown but can be associated with
condition of high HCG and estrogen level – Multiple pregnancy – Hydatidiform mole – A history of unsuccessful pregnancy and – First pregnancy
Note - A women who experience hyper emesis gravidarum will have a recurrence in subsequent pregnancy.
32BY GEBREMARYA TEMESGEN BSC MW
HEG Cont...
Assessing the mother condition
• Ask the women whether normal diet has been resumed & tolerated.
• Identify any event producing stress or anxiety as these may exacerbate any vomiting.
• Ascertain whether the nausea or vomiting is accompanied by pain of the location of any pain should be elicited.
33BY GEBREMARYA TEMESGEN BSC MW
HEG Cont........
• Dryness or inelasticity of the skin
• The mothers weight will be less than expected for gestation
• The pulse rate will be weak & rapid & the blood pressure will be low.
• Urine will be scant & dark in color & contain acetone
34BY GEBREMARYA TEMESGEN BSC MW
HEG Cont…
S/S of HEG:• Rapid pulse rate• Low BP• Dry and furred tongue• Her breath smells like Acetone • The pt becomes weak• Sunken eyes• Elevated HCT• Ketonuria• Wt loss• Inelastic skin teeth covered by sordes
35BY GEBREMARYA TEMESGEN BSC MW
HEG Cont...
Management: • Keep the woman NPO • Reassurance • Correct the electrolyte imbalance by intravenous fluid therapy (Na+
& K+ level) continuous the infusion until hydration & electrolyte returns to normal.
• Glucose to correct Ketoacidosisis• Anti emetics like promethazine may be used if vomiting persists• Sedatives to produce rest• Administer vitamin B12, C, Folic acid & iron to correct the anemia. • Observe the BP, Pulse rate & To at least 4hrly
36BY GEBREMARYA TEMESGEN BSC MW
HEG Cont.....
• Order urine test twice/ day for - specific gravity – Acetone, – Sugar &– Protein
• Measure intake & out put of fluid, includes vomits Note:• If vomiting is ceased for 24 hrs oral fluid can be started
& if this is tolerated a high carbohydrate diet may follow
• Then normal food is gradually introduced & IV therapy will be discontinued.
37BY GEBREMARYA TEMESGEN BSC MW
HEG Cont…
DDx:
• UTI, Appendicitis acute polyhydramnious, preeclampsia, acute intestinal obstruction, torsion of the ovarian cyst etc…
NB: Beware to exclude obstetric causes like
• Multiple pregnancy and
• Hydati form mole
38BY GEBREMARYA TEMESGEN BSC MW