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FILARIASIS
UNUSUAL COMPLICATION
Surgery unit I
Prof & HOD-Dr. N. K. Ray
Asst Prof – Dr. R. N. Singh
Presenter: Dr. Sk Sabir Ahmed
HISTORY 32yrs old Rajanna was suffering from
elephantiasis of his right leg for 16yrs. He was treated in Victoria hospital for the same
He has undergone plastic surgery procedure for the swollen limb, which failed &
14 yrs back above knee amputation was done. He was asymptomatic for 6yrs.
8 yrs back he has noticed one swelling in his Rt inguinal region which was gradually progressing.
2 yrs the swelling progressed rapidly to present size.
dragging type of pain in the swelling, also heaviness in limb the since last 2months.
No H/O fever with chills & rigors. No H/O cough, No H/O any other swelling, No H/O difficulty in passing urine. No H/O passage of milky urine. No H/O –DM - HTN - TB Family history: not significant Personal history: diet- mixed bowel & bladder- normal sleep- disturbed due to pain habits: alcoholic since 3 yrs( 1 quarter/day) smoker, chew betel nut occasionally
GENERAL PHYSICAL EXAMINATION Patient is Rt sided above knee amputee
& moderately nourished, conscious & cooperative.
Vitals – stable pallor - present, No- icterus, cyanosis, clubbing. No generalized lymphadenopathy.
LOCAL EXAMINATION Single irregular swelling, 20x
15x15cm in size situated over right groin extending from right anterior superior iliac spine(ASIS) to pubic symphysis & root of the right scrotum to 10 cm below the ASIS. Surface of the swelling bosselated. Hypo pigmented patch over the swelling.
On palpation tenderness present, no local rise of temperature, consistency firm to hard , restricted mobility in all the direction.
Skin adherent throughout except the periphery.
Penis & scrotum is deviated to opposite side.
Systemic examination: CVS : RS: NAD PA: CNS:
INVESTIGATION Hb - 10gm
TC - 8,600
Platelets - 2.5Lakhs
RBS - 147mg%
BU -12mg% Sr Cr -0.7mg% BT - 2.5min CT -3min HIV/HBsAg-negative Bld grp -o+ve
FNAC: microfilaria against
an edematous & inflammatory background.
Plain X ray- calcified lesion
in Rt groin.
CT scan: multiple calcified
lesion in the Right inguinal & thigh region.
Provisional diagnosis: Filarial lymphadenopathy.
Pre-op preparation was done : 1 pint blood given to improve anemia.
Under GA an elliptical incision was made below
the summit of the swelling
flaps were raised laterally over the swelling up to the muscle plane.
Femoral vessels, the right
spermatic cord & root of the penis
were protected.
swelling was ultimately dissected off the femoral triangle.
Perfect hemostasis secured during the whole surgery.
Specimen sent for histopathology.
Histopathology report:
soft tissue mass with
extensive fibrosis, calcification & ossification.
Post operative patient had lymphorrhea for about 15 days.
Lymphorrhea subsided & patient was discharged 1 month after operation
DISCUSSION Lymphedema of leg: Accumulation of the lymph in the subcutaneous
tissue results in enlargement of the limb. Fluid collects in the extracellular, extravascular compartment.
Causes of lymphadenitis Primary: Lymphatic aplasia: number of lymphatic
channels & nodes are grossly reduced Lymphatic hypoplasia: lymphatic channels are
small in caliber. Secondary : Filarial elephantiasis Following lymph node block dissection Following radiotherapy Advanced malignancy
FILARIASIS This is the most common cause of
lymphoedema worldwide, affecting up to
100 million individuals. It is particularly prevalent in Africa, India & south America where 5-10% of population may be affected.
filarial elephantiasis is caused by wuchereria bancrofti, transmitted by the mosquito(Culex fatigans). The disease is caused by adult worms which have the affinity towards lymphatic vessels & lymph nodes.
PATHOPHYSIOLOGY OF LYMPHOEDEMALymphatic obstruction
Lymphatic hypertension& distention
Accumulation of ISF, proteins, GF & other active peptide moieties, GAG & particulate matter including bacteria.
Increased collagen production by fibroblast
Accumulation of inflammatory cells
Activation of keratinocytes
End result is protein rich edema fluid, increased deposition of ground substance, subdermal fibrosis & dermal thickening & proliferation.
PATHOGENESIS Initially it causes
lymphangitis which clinically presents with high grade fever with chills & rigors, red streaks in the limbs.
PATHOGENESIS (COND…) The lymph nodes
are swollen & tender.
PATHOGENESIS (COND…) Due to such repeated
infections, fibrosis occurs resulting in lymphatic
obstructions. This later gives rise to
lymphatic dilatation. Lower limb lymphatics are dilated & tortuous(lymphangiectasis).
PATHOGENESIS (COND…) To start with
lymphoedema is pitting in nature & after some time becomes nonpitting in nature.
After repeated infections, the skin over the limb becomes dry thickened,
thrown in to folds and even nodules
which break open and results in ulcer, hence called elephant leg.
Reaction to adult worms in the Lymphatic vessels lead to
elephantiasis hydrocele
chyluria
Acute filarial
Lymphangitis abscess tropical
pulmonary
eosinophilia
lymphadenopathy
SPECIAL INVESTIGATION Lymphangiography : in this technique the lymphatic of the lower limb are delineated with radio opaque dye. Isotope lymphoscintigraphy: radioactive technetium labeled protein or
collied particles are injected into an interdigital web space & specifically taken up by lymphatics & serial radiograph are taken with gamma camera.
CT scan: MRI: USG:
TREATMENT OF FILARIAL LYMPHOEDEMAI. Conservative line of
management:• Rest & elevation of the limb.• Elastic crape bandage.• Diuretics.• Antifilarial treatment-
TREATMENT OF FILARIAL LYMPHOEDEMA
II. Surgery : Operation falls into 2 categories
Bypass procedure Reduction procedureIndication: indication: -proximal ilioingunal -for huge swollen limb lymphatic obstruction with normal distal lymphatic channels
BYPASS PROCEDURE Omental pedicle graft:Physiologic operations-
attempt to link subcutaneous tissue with deep lymphatics or to attach lymphatic bearing pedicles such as omentum or small bowel to the root of the affected limb.
Nodo venous shunt(Neibulowitz):
dilated, enlarged lymph node in the inguinal region is anatomized to a vein near by, eg.,
long saphaenous vein or femoral vein etc.
REDUCTION PROCEDURE Sistrunk operation
: A wedge of skin &
subcutaneous tissue is excised & wound closed primarily.
REDUCTION PROCEDURE Sistrunk operation
: A wedge of skin &
subcutaneous tissue is excised & wound closed primarily.
Homans operation:
First skin flaps are elevated,
Subcutaneous tissue are excised
Flaps are trimmed to accommodate the reduced girth of the limb & closed primarily.
Homans operation:
First skin flaps are elevated,
Subcutaneous tissue are excised
Flaps are trimmed to accommodate the reduced girth of the limb & closed primarily.
Swiss roll operation
(Thompson’s): in this a skin flap is raised containing dermis and is buried in to deep tissues (close to vascular bundle). This is a dermal flap prepared by denuding epidermis.
Swiss roll operation
(Thompson’s): in this a skin flap is raised containing dermis and is buried in to deep tissues (close to vascular bundle). This is a dermal flap prepared by denuding epidermis.
1. Clarke’s excision operation: in this operation , diseased skin and subcutaneous tissue are excised till the healthy underlying structures are seen f/b split skin grafting.
AIM OF PRESENTATION This case is a rare complication of
filariasis. The weight of the swelling was 4.5kg,
which was relieved after the surgery. This is the first case of filariasis
operated in our hospital.
THANK YOU