Loratadine : antihistamine ( 2nd generation )

Muhammad Koksh Sdiq

M.Sc in pharmacy

1

Scientific name :

loratadine

(OTC)

Generic name :

Loratin ;

Claritin .

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Dose & dosage form

Tablet 10mg Syrup 5mg/5ml

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Dosage & frequency

`` Adult and children above 12 years:

1 tablet or 2 teaspoonful once daily

``children 2 – 12 years:

Over 30 kg : 2 teaspoonful once daily

Under 30 kg : 1 teaspoonful once daily

`` children below 2 years :

As recommended by the physician .

Safety and efficacy not established .

4

Indications :

` ̀ the rapid relief of symptoms like sneezing , rhinorrhea , ocular itching and

stinging associated with seasonal ( hay fever ) perennial allergic rhino

conjunctivitis .

` ̀Pruritus in chronic and idiopathic urticarial.

` ̀itching in atopic dermatitis.

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Side effect

` Headache (12%)

` Drowsiness (8%)

` Somnolence (8%)

`Nervousness (4%)

`Fatigue (3-4%)

` dry mouth (3%)

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Caution

The drug is OTC , but caution must be takenduring hepatic and renal impairment and inelderly patients and in narrow angle glaucoma,prostatic hypertrophy , peptic ulcer andbladder neck obstruction, pregnancy , lactation, children under 2 years .

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Thank you

Are their any question ?

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