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The 20th International Congress of Nutrition (ICN) hosted by the International Union of Nutritional Science (IUNS) took place on the 15th-20th September 2013, Granada, Spain. WCRF International held a 2-hour symposium on the Continuous Update Project (CUP) entitled ‘Food, Nutrition, Physical Activity and Cancer – Keeping the Evidence Current: WCRF/AICR Continuous Update Project (CUP).’ It included four presentations exploring the latest updates from the CUP.
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Alan A Jackson
University of Southampton, UK
NIHR Southampton Biomedical Research Unit
in Nutrition
IUNS 20th International Congress of Nutrition
“Joining Cultures Through Nutrition”
WCRF/AICR: Continuous Update Project (CUP)
Future Implications
http://www.dietandcancerreport.org/cancer_resource_center/cup_summaries.php
http://www.dietandcancerreport.org/cancer_resource_center/downloads/cu/Pancreatic-Cancer-2012-Report.pdf
http://www.dietandcancerreport.org/cancer_resource_center/downloads/cu/Colorectal-Cancer-2011-Report.pdf
http://www.dietandcancerreport.org/cancer_resource_center/downloads/cu/Breast-Cancer-2010-Report.pdf
http://www.wcrf.org/PDFs/CUP-reports-SLRs/Endometrial-Cancer-2013-Report.pdf
Breast cancer 2010
Evidence for all factors was consistent with the conclusions from the Second Expert Report
Colorectal cancer 2011
• Foods containing dietary fibre upgraded from probable to convincing
Pancreatic cancer 2012
Foods containing folate downgraded from probable decreases risk
Endometrial cancer 2013
New conclusions for coffee and glycaemic load
Shift from exogenous toxins to endogenous factors
External factors that act to produce cancer Toxins Infections
Structural Adiposity Adult achieved height
Previous mechanisms of carcinogenesis
Current mechanisms of carcinogenesis
External exposures substantially reduced
Extremely efficient systems for protection
Failure of protection against cancer Internal control stressed beyond ability to
cope Resilience vs allostatic load
More detailed consideration cellular level interactions
Obesity Energy macronutrients Other nutrients Regulate and control processes
Understanding the nature of processes DNA stability and repair Energy flux Inflammatory processes Oxidative damage Regulation of cell cycle
Need for more integrated information
By 2015
CUP database complete and continually updated
By 2017
Review of Cancer Prevention Recommendations
Review of mechanisms
Review of breast cancer survivors
Implications for Policy
KEY CUP DATES
