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• 50,000 strokes – ¼ under age 55
• 10,000 dead – No. 3
• 20,000 disabled – No. 1
Imaging the Penumbra
No penumbra = no benefit likely
Translation – animal to human
Imaging the vessels
Better clot busting drugs
• TNK
• DSP
Better access to proven therapies
Number needed to transport = 2.5