Glycomet (Metformin Tablets)
Metformin Tablets
Clearsky Pharmacy
Glycomet Tablets (Metformin Hydrochloride) is used along with a
proper diet and exercise in the treatment of type 2 diabetes. It
improves glucose tolerance in patients with type 2 diabetes,
lowering both basal and postprandial plasma glucose.
Glycomet Tablets
Clearsky Pharmacy
Glycomet Tablets are manufactured by USV Limited (Website:
www.usvindia.com )
Metformin Hydrochloride Tablets Brand Names
Clearsky Pharmacy
Metformin Hydrochloride tablets are available as Glucophage,
Glycomet, Glycomet SR, Exermet, Exermet XR, Fortamet, Actoplus Met,
Avandamet, Glucophage, Glumetza and Riomet.
Active Ingredient
Clearsky Pharmacy
The active ingredient contained in Glycomet is Metformin
Hydrochloride. Each tablet contains 250 mg, 500 mg, 850 mg or 1000
mg of Metformin hydrochloride IP
Chemical Structure
Clearsky Pharmacy
The structure of Metformin Hydrochloride is given below:
Uses of Glycomet Tablets
Clearsky Pharmacy
Glycomet (Metformin Tablets) is indicated along with diet and
exercise, to improve glycaemic control in adults with type 2
diabetes mellitus. Glycomet can be used together with a
sulphonylurea or insulin to improve glycaemic control in adults.
Metformin tablets help to control the amount of glucose (sugar) in
your blood. This medicine decreases the amount of glucose you
absorb from your food and the amount of glucose made by your
liver.
Storage Instructions
Clearsky Pharmacy
Glycomet (Metformin Tablets) have to be stored at controlled
room temperature i.e. from 20C to 25C (68F to 77F) with excursions
permitted between 15 to 30C (59 to 86F). Store in a cool, dry place
away from light.Keep this as well as all other medicines away from
children and pets.
Metformin Dosage
Clearsky Pharmacy
The normal adult starting dose is one 500 mg tablets three times
daily. This dose or alternatively one 850mg tablet twice daily may
be enough to provide good diabetic control.
When Metformin therapy is used along with with sulphonylurea or
insulin therapy
patients must have their blood-sugar levels monitored due to the
possibility of hypoglycaemia occurring.
The dosage of Glycomet tablets (Metformin Hydrochloride) is
given below:
Warnings
Clearsky Pharmacy
The risk of lactic acidosis increases with the degree of renal
dysfunction, impairment of creatinine clearance and the patient's
age.Since impaired hepatic function can significantly limit the
ability to clear lactate, metformin should generally be avoided in
patients with clinical or laboratory evidence of hepatic
disease.
Warnings
Clearsky Pharmacy
Patients must be warned against excessive alcohol intake either
acute or chronic when taking metformin, since alcohol consumption
potentiates the effect of metformin on lactate metabolism.
Administration of Glycomet Tablets should be temporarily
discontinued two days prior to any intravascular radiocontrast
study and not restarted until renal function has normalised.
Glycomet Tablets
Clearsky Pharmacy
Contraindications
Glycomet tablets are contraindicated in patients with a
hypersensitivity to Metformin Hydrochloride or any other component
of this medication. Glycomet (Metformin Tablets) is contraindicated
in patients with a history of ketoacidosis with or without coma or
with significant renal impairment.They are also contraindicated in
cases of severe hepatic dysfunction, excessive alcohol intake
either acute or chronic, cardiovascular collapse and in disease
states associated with hypoxemia
Glycomet Tablets
Clearsky Pharmacy
Contraindications
Glycomet tablets are contraindicated in patients during stress
conditions e.g. severe infections, trauma, or surgery or the
recovery stageThereafter.States associated with lactic acidosis
e.g. shock or pulmonary insufficiency.Patients with a history of
lactic acidosis irrespective of the precipitating factors and
patients suffering from severe dehydration.
Glycomet Side Effects
Clearsky Pharmacy
Glycomet side effects can include headache or muscle pain,
weakness, gastrointestinal upset, including cramps, mild nausea,
vomiting, diarrhea increased flatulence, gas, and stomach pain.
The most serious potential side effect of metformin use is
lactic acidosis; this complication is very rare, and the vast
majority of these cases seem to be related to comorbid conditions,
such as impaired liver or kidney function, rather than to the
Metformin itself.
Call your doctor at once in case you have any other serious side
effect such as: Feeling short of breath, even with mild exertion;
Swelling or rapid weight gain; or Fever, chills, body aches, flu
symptoms.
Glycomet Overdose
Clearsky Pharmacy
Adverse reactions of a more intense character including
epigastric discomfort, nausea and vomiting followed by diarrhoea,
drowsiness, weakness, dizziness, malaise and headache may be
observed. In case these symptoms persist, lactic acidosis must be
excluded. Hypoglycaemia has not been seen even with ingestion of up
to 85g metformin although lactic acidosis has occurred in such
circumstances.Hypoglycaemia can occur if excessive amounts of
Metformin tablets (Glycomet) are taken with a sulphonylurea,
insulin or alcohol.
Overdose
Clearsky Pharmacy
Metformin tablets must be discontinued and proper supportive
therapy instituted. Metformin can be dialysable with a clearance of
up to 170mL/min under good haemodynamic conditions.
Glycomet During Pregnancy
Clearsky Pharmacy
Glycomet (Metformin Hydrochloride tablets) has been classified
by the US FDA as Pregnancy Category B. There are no adequate and
well-controlled studies for Metformin tablets conducted in pregnant
women. Recent information strongly suggests that abnormal blood
glucose levels during pregnancy are associated with the higher
incidence of congenital abnormalities. Most experts recommend that
insulin be used during pregnancy to maintain the blood glucose
levels as close to normal as possible. Metformin tablets should not
be used in pregnancy unless clearly required.
Glycomet Tablets
For more details on Glycomet Tablets click here
Clearsky Pharmacy
Glycomet (Metformin Tablets) by USV Limited, India.
