October 2009 . Volume 150 . Number 10

Endocrinology

October

2009.V

olume

150.N

umber

10.pages

4463–4818Endocrinology

The Endocrine Society8401 Connecticut Avenue, Suite 900

Chevy Chase, Maryland 20815-5817 USAPhone: 301-951-2615 / Fax: 301-951-2617

Mission Statement of The Endocrine SocietyThe mission of The Endocrine Society is to advance excellence in endocrinology and promote its essential

role as an integrative force in scientific research and medical practice.

THE ENDOCRINE SOCIETY 2009-2010

ROBERT A. VIGERSKY, PresidentKELLY E. MAYO, President-ElectROBERT M. CAREY, Past PresidentLISA H. FISH, Vice-President—Physician-in-Practice

CAROLE R. MENDELSON, Vice-President—Basic ScienceNANETTE F. SANTORO, Vice-President—Clinical ScienceANDREW F. STEWART, Secretary-TreasurerJOHN C. MARSHALL, Secretary-Treasurer Elect

PUBLICATIONS CORE COMMITTEE—MARGARET A. SHUPNIK, Chair

COUNCIL—ROBERT M. CAREY, LISA H. FISH, JAN-ÅKE GUSTAFSSON, JENNIFER L. LARSEN, SUSAN J. MANDEL,JOHN C. MARSHALL, KELLY E. MAYO, DONALD MCDONNELL, CAROLE R. MENDELSON, MARK MOLITCH,ALVIN C. POWERS, NANETTE F. SANTORO, ANDREW F. STEWART, PETER TRAINER, ROBERT A. VIGERSKY,TERESA WOODRUFF. EX OFFICIO: SCOTT HUNT, MARGARET E. WIERMAN, JOY Y. WU.SCOTT HUNT, Executive Director and CEO

INSTRUCTIONS TO AUTHORS AND ETHICAL GUIDELINES: These appear in the first issue of each volume andat http://jcem.endojournals.org. The online versions of these documents should be treated as the most current.

CHANGE OF ADDRESS: Notify The Endocrine Society 60 days in advance using the contact information above.

DISCLAIMER: The statements and opinions in Endocrine Society journal articles are solely those of the authors andnot of The Endocrine Society. Advertisements are solicited and placed without knowledge of the particular order ofarticles in any issue. The Editors are not permitted to engage in discussions about Journal content for forthcoming issueswith agencies involved in soliciting advertisements, or companies purchasing advertising space. The Endocrine Societydoes not evaluate advertised products or services nor assess advertising claims. The appearance of advertising in TheEndocrine Society’s publications, or reference to a product or service within a paper published by The Endocrine Society,do not constitute endorsements by The Endocrine Society. The Endocrine Society reserves the right to decline anyadvertisement in its discretion.

CLASSIFIED ADVERTISING: Contact The Endocrine Society Placement and Classified Advertising, c/o ChristineWhorton, 12366 N. Red Mountain Drive, Tucson, AZ 85737 USA. Phone: 800-361-3906 or 520-544-2760; Fax:520-297-4466; Email: placement@endo-society.org

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Website: http://endo.endojournals.org

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ENDOCRINOLOGY

Affirmation of Originality and Assignment of CopyrightFax this form to:

Jeffrey D. Blaustein, Ph.D., Editor-in-Chief, Endocrinology8401 Connecticut Avenue, Suite 900Chevy Chase, MD 20815-5817, USA301-951-2615 (phone) 301-951-2617 (fax)

Manuscript No.:

The author(s) hereby affirms that the manuscript entitled:

is original, that all statements asserted as facts are based on author(s) careful investigation and research for accuracy, that the manuscriptdoes not, in whole or part, infringe any copyright or violate any right of privacy or other personal or property right whatsoever, that ithas not been published in total or in part and is not being submitted or considered for publication in total or in part elsewhere, and thatauthor(s) has full power and authority to enter into this copyright assignment and to make the grants herein contained.

In signing this form, each author acknowledges that he/she participated in the work in a substantive way and is prepared to take publicresponsibility for the work. If the above statement cannot be certified, justification for duplicate publication and permission to republishcopyrighted material must be included with the covering letter. Please include a statement declaring any commercial relationships that maypertain to this paper.

In signing this form, each author further affirms that he or she has read and understands the “Ethical Guidelines for Publication of Research”and consents to the investigation of any improprieties or violations thereof that may be alleged. Each author further releases and holdsharmless The Endocrine Society from any claim or liability that may arise therefrom.

The author(s), in consideration of the acceptance of the above work for publication, does hereby assign and transfer to The EndocrineSociety all of the rights and interest in and to the copyright of the above titled work in its current form and in any form subsequently revisedfor publication and/or electronic dissemination and does hereby appoint The Endocrine Society to obtain all right, title, and interest to thecopyright for the above titled work.

Publication Charge Agreement: The undersigned agree to honor publication charges as outlined in the Instructions to Authors if themanuscript is published.

The Journals are copyrighted by The Endocrine Society to protect The Society and authors from unauthorized use of its contents. TheSociety grants to authors the royalty-free right of republication in any work of which they are the author or editor, subject only to givingproper credit in the work to the original publication of the article by The Endocrine Society. Therefore, authors do not need to contactThe Endocrine Society office to request permission to reproduce their work.

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______Check here if this article exists in the public domain because it was written as part of the official duties of any of the authors asemployees of a government. A signature confirming authorship is still required for each author.

Full Instructions to Authors and Ethical Guidelines for Endocrinology can be found in the first issue of each volume and http://endo.endojournals.org/. The online versions of these documents should be treated as the most current.

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