RASAYANARASAYANAan updated viewan updated view

Dr. M.R.Vasudevan Nampoothiri MD(Ay)FORMER DIRECTOR

AY. MEDICAL EDUCATION , KERALA

PROFESSOR ,

AMRITA SCHOOL OF AYURVEDA

शतं जि�व शरदो वर्ध�मानशतं हेमन्तान् शतम वसन्तान्शतं इन्द्राग्नि�न सविवता बृहस्पवितशतायुषा हविवषेमं पुनर्द्दु"�ः (ॠ�वेदम्)The desire to live as long as it is humanly possible

has been ingrained in man even from Vedic times. The benediction worded, “May you live

through a hundred summers and winters” is an evidence to this.

Psoriasis vulgaris

Psoriasis vulgaris-Psoriasis vulgaris-Inclusion criteriaInclusion criteria

CLINICAL HISTOLOGICAL

Itching HyperkeratosisScaling ParakeratosisThickening Cylindrical rete ridgesErythema Inflammatory cellsDrynessAuspitz sign

Acacia catechu. Willd.

Family : Leguminosae

a. Thuvaraka seeds

b. Thuvaraka taila (plain)

c. Thuvaraka taila prepared with three times khadira kwatha.

ThuvarakaPlant - Twig

Clinical featuresClinical featuresGroup A

Sodhana + rasayana :- 86% of the patients with moderate and severe illness came to the group under mild illness.

Group BSodhana only :- No change in moderate and severe illness.

Histological featuresHistological features

Group A100% of the patients under the group ‘severe’ came to the group ‘mild’

Group BNo significant change occurred

Psoriasis vulgarisPsoriasis vulgarisSodhana + Thuvaraka

rasayana

Significant changes inclinical and histological

parameters

Sodhana only

Changes inclinical

parameters only

Follow up - after 3 monthsFollow up - after 3 months

Sodhana + Thuvaraka rasayana

Significant clinical

improvement as well as histological changes seen,only

mild superficial keratosis persisted

Sodhana only

Only clinical improvement,

no histological changes

Section of Skin

Just after treatment

After 3 months

Before treatment

SAMANYA SAMPRAPTHISAMANYA SAMPRAPTHINidana

Dosha dushti

Dhathu dushti

Dhathu vikruthi

Recurrence of the disease

Secondary diseases

Early ageing process

Lakshanas

Sodhana ChikitsaEliminates the dosha vitiationCorrects the functions of dhatusFails to correct the structural deformityof the dhatus as it acts only in the doshic level

Rasayana ChikitsaCorrects the structural deformity of the dhatus there by normalising the functionsStrengthens the dhathus

Prevents the instinct of recurrencePrevents secondary diseasesPrevents early ageing process

Sodhana chikitsa against Sodhana chikitsa against Rasayana ChikitsaRasayana Chikitsa

Vatakapha rogas - PrognosisVatakapha rogas - Prognosis Srothorodha caused by the vitiation

of kapha leads to defective transformation of dhatus

Agni vaishamya caused by the vitiation of vata leads to defective formation of dhatus

In almost all the vatakapha rogas pitha will be inhibited resulting in agnimandya

…….. Vatakapha rogas - Prognosis.. Vatakapha rogas - Prognosis

As agnimandya takes a major role in the samprapthi of all the diseases; it is doubled in the case of vatakapha rogas

There is no such rasa which can be used commonly against vata and kapha.

Sodhana chikitsa

Srothonirmalatha Peyadikramam

Dhathusudhi Kayagnideepthi Dhatwagnideepthi

Rasayanaprayogam

Ojovridhi

DEERKHAYUS

Rasayana Oushadhas are not having a common rasa, veerya or guna but all are Srothosodhana and Deepana.

Normal Functioning of srothases (Srothosoushtava) is highly essential to convey the nutrients to each and every cell.

Sodhana Therapy acts at the level of doshas, but rasayana drugs act still deeper, that is at the level of dhatus.

Hence in deep - seated diseases rasayana chikitsa is the line of choice.

As ageing is a chronic degenerative and deep – seated problem rasayana chikitsa is the regime of choice.

“ Very few, if any, reach their potential maximum life span; they die, instead,

prematurely of a wide variety of diseases, the vast majority being of

free radical diseases ” (Dr. Denham Halman MD; PhD

Father of free radical medicine)

FREE RADICALSFREE RADICALS Definition : A free radical has been defined as

“any species capable of independent existence that contains one or more unpaired electrons.”

As the body ages or is subjected to environmental pollutants, such as cigarette smoke, over exposure to sunlight, or smog, the body become overwhelmed by FR’s.

…………FREE RADICALSFREE RADICALS

Free radicals are generated as a result of incomplete reduction of oxygen during the course of various biochemical reactions.these highly reactive oxygen derived FR’s have a life span of a few micro seconds and their concentration at any site is miniscule. Excessive production of FR’s can overwhelm the intrinsic antioxidant defence mechanisms leading to many pathological lesions.

Anti oxidantsAnti oxidantsAnti oxidants can be defined as

substance whose presence in relatively low concentrations

significantly inhibits the action of free radicals.

All the Rasayana drugs are having anti oxidant property.

Rasayana drugs and Rasayana drugs and pharmacological propertiespharmacological properties

Emblica – Officianalis(Amla) fruit Terminalia chebula(Haritaki) fruitWithania somnifera(Aswagandha) rootTinospora cordifolia(Guduchi) satwaTerminalia arjuna(Arjuna) Stembark

Antioxidant, nutritive

Antioxidant

Adaptogenic, antioxidant

Immunomodulatoryantioxidant

Hypocholestrolemicantioxidant.

Courtesy : Prof. Dr.S.Venkataraman Professor of Pharmacology, University of Madras.

DegenerationDegeneration Means deterioration and loss of

specialized function of the cells of tissue or organ, by defective blood supply or diseases.

But clinically it usually refers to that of CNS & joints.

Vatavridhi Srothokharathwam(soushtavahani)

Ojakshayam Aaharasaraagiranavaigunyam

Utharotharadhathukshayam Upachayapachayaasamatha

Rasadhathukshayam

Vardhakyam

अस्थि'ः�ायतेवर्द्ध�ते विवपरिरणामतेअपक्षीयतेनश्यते

Stage of administration of Stage of administration of RasayanasRasayanas

Stage of administration of Rasayanas.

…… …… another viewanother view

KaphaBalyaKaphapitha AdolescentPitha Youvana

Pithavata Age of administration

of rasayanas

Vata Vardhakya

Action of Rasayanas in Action of Rasayanas in degenerative diseasesdegenerative diseases

Pithavata

Vata

Agnivaishamya

Rasadhathwagni mandya

Increase in the malarupa kapha

Vatakapha vikara

Importance of Ghritha in Importance of Ghritha in preventing CNS degenerationpreventing CNS degeneration

There is similarity between ghritha and brain matter

Only fat and alcohol soluble materials can cross the blood brain barrier

So ghritha is the only medium that can nourish brain

Lack of use of milk products, especially gritha is one of the major etiology of neurological degeneration.

Some rasayanas and their Some rasayanas and their indicationsindications

Brahmarasayanam

Narasimharasayanam

Thippalirasayanam

Bhallathakarasayanam

Lasunarasayanam

Vatika hridroga, improves immunity

Oligospermia, increases vigour and vitality

Thamakaswasa, vatasonitha

Found effective in malignancy, vatasonitha

Various neurological disorders including MND’s

Rasayanas in some diseasesRasayanas in some diseases

Vatapaithika vatasonithaVatakaphaja vatasonithaVatika HridrogaKaphajahridrogaPramehaSushkaarsasThamakaswasa

Chyavanaprasam Bhallathakarasayanam Brahmarasayanam Agasthyarasayanam Silajathurasayanam Bhallathakarasayanam Thippalirasayanam

Need of RasayanasNeed of Rasayanas1. A vehicle with a strong axle runs

its full course because of the quality of its axle. Likewise our life also will run its full course

by maintaining the body carefully and systematically; if not the body decays (rapidly).

रसायनेन ह्यसाध्यो व्यधिर्धरेण प्रयः सिसर्द्दुयते (सु. सं.)रसायनावि4ना असाध्यतां यान्तिन्त (डल्हण )Even the incurable diseases

respond well to rasayana

Rasayana therapyRasayana therapy the possible mechanisms of actionthe possible mechanisms of action

Nourishes and maintains the cell life (Neutriceutical action).

Encourages the growth of new cells (Regenerative action).

Prevents recurrent infection, expelling the damaged cells (Immunomodulatory action).

Eliminates the toxic metabolites and pollutants (Antioxidant action).

Maintains the balance between mind and body (Adaptogenic).

Rasayana drugs act at the subcellular level.

Rasayana in the present Rasayana in the present scientific scenarioscientific scenario

“The delicate, controlled elimination of cells is called programmed cell death.”

Excessive cell death - AIDS, neuro degenerative diseases, stroke and myocardial infarction.

Undue survival of cells - auto immune conditions and cancer.Rasayana may help to normalise the PCD

there by preventing the above clinical conditions.

Futuristic application of Futuristic application of RasayanasRasayanas

The application of genome code theory may create a disease free universe.

The most important therapy of the era may be Rejuvenative.

Our Rasayanas will be on top!!!

THE ULTIMATE ACHIEVEMENTTHE ULTIMATE ACHIEVEMENT

THE SCIENTIFIC USE OF RASAYANAS WILL PROVIDE

A GRACEFUL AGEING

“Who ever makes proper use of Rasayana attains longevity

on earth and after death follows the path of sages to

reach immutable”.

Charaka Samhitha Charaka Samhitha Chikitsasthana 1:1:80Chikitsasthana 1:1:80

Thank you