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Retina – what are your concerns Somdutt Prasad MS FRCSEd FRCOphth FACS Consultant Ophthalmologist I4vison, 13 A, Jatin Bagchi Road, Kolkata 70029 AMRI Medical Centre, 97 A, Kolkata 700029 Divyadrishti, Howrah Westbank Hospital, Andul Road, Howrah [email protected] 098 30 50 7754

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  1. 1. Retina what are your concerns Somdutt Prasad MS FRCSEd FRCOphth FACS Consultant Ophthalmologist I4vison, 13 A, Jatin Bagchi Road, Kolkata 70029 AMRI Medical Centre, 97 A, Kolkata 700029 Divyadrishti, Howrah Westbank Hospital, Andul Road, Howrah [email protected] 098 30 50 7754
  2. 2. UK Training Dorchester Rick Powell 1994 Swindon Paul McCormack 1995 Oxford 1996 Paul Rosen & Hung Cheng Wirral Russell P Phillips -1997-1999 Sheffield Prof Ian Rennie, John Talbot, James West 2000-2001
  3. 3. MS Kolkata 1993 FRCS Edinburgh 1994 CCST - 2001 FRCOphth (London) 2006 FACS American College of Surgeons 2008 AAO Achievement Award 2008 AAO International Education Award 2009 ASCRS Film Festival Award 2010 ASRS Honors Award 2013
  4. 4. The Retinal Surgeon - 1995 Is your retina detached? Do you have a cataract? No! What are you doing in my clinic?
  5. 5. DIABETIC VITRECTOMY
  6. 6. What do I do? Medical Retina Vitreo-retinal surgery Cataract surgery Premium IOLs Toric IOLs Multifocal IOLs
  7. 7. Diabetes 1550 BC - Ebers Papyrus of ancient Egypt too great emptying of urine the river Nile between the thighs Remedies recommended diet of wheat grains, grapes, honey and berries Papyrus discovered - Luxor 1872 George Maurice Ebers
  8. 8. Diabetes 17.1 crores worldwide India 2000 3.17 crores 36.6 crores in 2030 Maximum increase in India 7.94 crores India 4.23 crores China
  9. 9. Life Expectancy of Function (Years) Behaviour & Environment Good Bad VitalFunction% Failure 0 100 10025 50 75
  10. 10. India One Ophthalmologist / 1 lakh population UK 2.3 Ophthalmologists / 1 lakh population 70% + specialists - Urban 70% + population - Rural
  11. 11. Diabetic Retinopathy - Classification Background Proliferative Advanced Diabetic Eye Disease Preproliferative Maculopathy The commonest cause of decreased visual acuity due to diabetic retinopathy is maculopathy
  12. 12. Examination Slit lamp External exam Pressure measurements Fundus examination
  13. 13. 11 November 1998 Retinal Examination Direct Ophthalmoscope small field 2 D view Uniocular
  14. 14. Retinal Examination (2) Slit lamp biomicroscopy Large field 3 D view Binocular
  15. 15. Binocular indirect ophthalmoscope
  16. 16. Retinal Examination Fundus photography Large field Can be done by technician
  17. 17. Laser treatment for diabetic retinopathy is effective.
  18. 18. Diabetic maculopathy
  19. 19. Diabetic maculopathy 12% of treated eyes developed moderate visual loss in spite of treatment Less than 3% of treated eyes improved VA significantly (15 ETDRS letters)
  20. 20. Intra vitreal triamcinolone IVTA
  21. 21. Personal experience10+ years Pre 6/60 Post 6/9
  22. 22. Case 2 Pre RE 6/36 Pre LE 6/60 Post RE 6/9 Post LE 6/12
  23. 23. Steroids Triamcinolone Pseudophakic eyes Resistant cases Dexamethasone Ozurdex Fluocinolone Acetonide Iluvien, Retisert
  24. 24. Sustained Delivery Fluocinolone Acetonide Vitreous Inserts Provide Benefit for at Least 3 Years in Patients with Diabetic Macular Edema Peter A. Campochiaro, MD, David M. Brown, MD, Andrew Pearson, MD, Sanford Chen, MD, David Boyer, MD, Jose Ruiz-Moreno, MD, Bruce Garretson, MD, Amod Gupta, MD, Seenu M. Hariprasad, MD, Clare Bailey, MD, Elias Reichel, MD, Gisele Soubrane, MD, Barry Kapik, MS, Kathleen Billman, BS, Frances E. Kane, PhD, Kenneth Green, PhD Ophthalmology Volume 119, Issue 10, Pages 2125-2132 (October 2012) Copyright 2012 American Academy of Ophthalmology Terms and Conditions
  25. 25. Figure 5 Ophthalmology 2012 119, 2125-2132DOI: (10.1016/j.ophtha.2012.04.030) Copyright 2012 American Academy of Ophthalmology Terms and Conditions
  26. 26. Ranibizumab 9 RCTS in DME READ-2 REVEAL RESOLVE RESTORE RISE & RIDE DRCRN trial 2 years 10 letters gain in BCVA No difference between Ranibizumab + prompt laser (deferred laser worse) Laser alone
  27. 27. Bevacizumab 8 RCTS in DME BOLT Avastin vs Laser N=80, two years iVB +8.6 letters Laser -0.5 letters
  28. 28. Key points Laser therapy = standard of care non-center-involving oedema DME without decreased VA anti-VEGF treatment standard in center-involving DME and VA of 6/9 or worse Ranibizumab injections monthly for 3 visits, then as needed depending on VA (with or without OCT) stability
  29. 29. [email protected] 09830507754