Embed Size (px)
DESCRIPTION
Carlos Gabriel Contreras.Capacidad univariada de las interleuquinas para diferenciar entre EAS, AR y A
Citation preview
Capacidad univariada de las interleuquinas para diferenciar
entre EAS, AR y A.
Contrastes no parametricos.
Test Statisticsa,b
9,727 13,650 11,920 8,711 1,607 9,951
2 2 2 2 2 2
,008 ,001 ,003 ,013 ,448 ,007
Chi-Square
df
Asymp. Sig.
IL - 6 pg/ml IL - 1Bpg/ml IL - 8 pg/ml IL - 12 pg/ml TNF a pg/ml IL - 10 pg/ml
Kruskal Wallis Testa.
Grouping Variable: Grupo de pertenenciab.
Contrastes independientes de las IL.
Ranks
18 18,14 326,50
12 11,54 138,50
30
18 16,61 299,00
12 13,83 166,00
30
Grupo de pertenenciaEAS
AR
Total
EAS
AR
Total
IL - 1Bpg/ml
IL - 8 pg/ml
N Mean Rank Sum of Ranks
Test Statisticsb
60,500 88,000
138,500 166,000
-2,396 -,847
,017 ,397
,043a
,415a
Mann-Whitney U
Wilcoxon W
Z
Asymp. Sig. (2-tailed)
Exact Sig. [2*(1-tailedSig.)]
IL - 1Bpg/ml IL - 8 pg/ml
Not corrected for ties.a.
Grouping Variable: Grupo de pertenenciab.
Comparación de la IL 1B y la IL8 en EAS y AR.
Comparación de la IL 1B y la IL8 en EAS y OA.
Ranks
18 14,56 262,00
18 22,44 404,00
36
18 13,72 247,00
18 23,28 419,00
36
Grupo de pertenenciaEAS
OA
Total
EAS
OA
Total
IL - 1Bpg/ml
IL - 8 pg/ml
N Mean Rank Sum of Ranks
Test Statisticsb
91,000 76,000
262,000 247,000
-2,332 -2,723
,020 ,006
,024a
,006a
Mann-Whitney U
Wilcoxon W
Z
Asymp. Sig. (2-tailed)
Exact Sig. [2*(1-tailedSig.)]
IL - 1Bpg/ml IL - 8 pg/ml
Not corrected for ties.a.
Grouping Variable: Grupo de pertenenciab.
Comparación de la IL 1B y la IL8 en AR y OA
Ranks
12 9,75 117,00
18 19,33 348,00
30
12 9,50 114,00
18 19,50 351,00
30
Grupo de pertenenciaAR
OA
Total
AR
OA
Total
IL - 1Bpg/ml
IL - 8 pg/ml
N Mean Rank Sum of Ranks
Test Statisticsb
39,000 36,000
117,000 114,000
-3,229 -3,052
,001 ,002
,003a
,002a
Mann-Whitney U
Wilcoxon W
Z
Asymp. Sig. (2-tailed)
Exact Sig. [2*(1-tailedSig.)]
IL - 1Bpg/ml IL - 8 pg/ml
Not corrected for ties.a.
Grouping Variable: Grupo de pertenenciab.
Identificación de factores inmunológicos.
Análisis factorial.
KMO and Bartlett's Test
,646
68,542
15
,000
Kaiser-Meyer-Olkin Measure of SamplingAdequacy.
Approx. Chi-Square
df
Sig.
Bartlett's Test ofSphericity
Total Variance Explained
2,296 38,272 38,272 2,296 38,272 38,272
1,142 19,038 57,310 1,142 19,038 57,310
,972 16,199 73,510
,895 14,910 88,420
,514 8,570 96,989
,181 3,011 100,000
Component1
2
3
4
5
6
Total % of Variance Cumulative % Total % of Variance Cumulative %
Initial Eigenvalues Extraction Sums of Squared Loadings
Extraction Method: Principal Component Analysis.
Component Matrixa
-,198 -,433
,044 ,702
-,071 ,648
,909 -,156
,912 -,032
,770 ,130
IL - 6 pg/ml
IL - 1Bpg/ml
IL - 8 pg/ml
IL - 12 pg/ml
TNF a pg/ml
IL - 10 pg/ml
1 2
Component
Extraction Method: Principal Component Analysis.
2 components extracted.a.
Rotated Component Matrixa
-,173 -,444
,004 ,703
-,108 ,643
,916 -,103
,912 ,020
,761 ,174
IL - 6 pg/ml
IL - 1Bpg/ml
IL - 8 pg/ml
IL - 12 pg/ml
TNF a pg/ml
IL - 10 pg/ml
1 2
Component
Extraction Method: Principal Component Analysis. Rotation Method: Varimax with Kaiser Normalization.
Rotation converged in 3 iterations.a.
Rotated Component Matrixa
-,174 -,443
,006 ,703
-,107 ,643
,916 -,105
,912 ,018
,762 ,172
IL - 6 pg/ml
IL - 1Bpg/ml
IL - 8 pg/ml
IL - 12 pg/ml
TNF a pg/ml
IL - 10 pg/ml
1 2
Component
Extraction Method: Principal Component Analysis. Rotation Method: Quartimax with Kaiser Normalization.
Rotation converged in 3 iterations.a.
Component Matrixa
-,198 -,433
,044 ,702
-,071 ,648
,909 -,156
,912 -,032
,770 ,130
IL - 6 pg/ml
IL - 1Bpg/ml
IL - 8 pg/ml
IL - 12 pg/ml
TNF a pg/ml
IL - 10 pg/ml
1 2
Component
Extraction Method: Principal Component Analysis.
2 components extracted.a.
Análisis de función discriminante.
Factor inmune/Linfocito T como mejor discriminante entre EAS, AS y OA
Resumen de la función discriminante.
Variables Entered/Removeda,b,c,d
Factorinmunitario/Linfocito T.
,580 1 2 45,000 16,291 2 45,000 ,000
Step1
Entered Statistic df1 df2 df3 Statistic df1 df2 Sig.
Exact F
Wilks' Lambda
At each step, the variable that minimizes the overall Wilks' Lambda is entered.
Maximum number of steps is 4.a.
Minimum partial F to enter is 3.84.b.
Maximum partial F to remove is 2.71.c.
F level, tolerance, or VIN insufficient for further computation.d.
Curvas COR
Factores Macrófago y linfocito T
Curva COR para OACase Processing Summary
18
30
Grupo de pertenenciaPositivea
Negative
Valid N(listwise)
Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.
The positive actual state is OA.a.
Curva COR para OA
Case Processing Summary
12
36
Grupo de pertenenciaPositivea
Negative
Valid N(listwise)
Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.
The positive actual state is AR.a.
Curva COR para EASCase Processing Summary
18
30
Grupo de pertenenciaPositivea
Negative
Valid N(listwise)
Larger values of the test result variable(s) indicatestronger evidence for a positive actual state.
The positive actual state is EAS.a.
Perfiles de compromiso inmunológico.
Indicadores moleculares de gravedad.
IL-6
IL 1B
IL 8
TNF a e IL 12
IL 10
Factor inmunitario Macrófago.
Factor inmunitario Linfocito T
Correspondence Table
15 3 18
12 0 12
9 9 18
36 12 48
Grupo de pertenenciaEAS
AR
OA
Active Margin
Perfil decompromiso
inmunològicobajo
Perfil decompromiso
inmunològicoalto. Active Margin
Compromiso inmunològico
Summary
,471 ,222 1,000 1,000 ,113 ,471
,222 10,667 ,005a 1,000 1,000
Dimension1
Total
SingularValue Inertia Chi Square Sig. Accounted for Cumulative
Proportion of Inertia
StandardDeviation Correlation
Confidence SingularValue
2 degrees of freedoma.
Análisis de correspondencia entre EAS, AR, OA y perfiles de
compromiso inmune.
