Jeans for Genes day!

Friday 7th October

We’re changing the world for children with genetic disorders.All you have to do is wear your jeans.

Facts about genetic disorders

It is estimated that 2.8m people in the UK are affected by rare genetic disorders* (2m are affected by cancer)

An estimated 1 in 25 children born in the UK is affected by a genetic disorder / birth defect, that equates to more than 30,000 babies born in the UK each year

There are more than 4,500 recognised genetic disorders

Genetic disorders are the biggest cause of death for children aged 14 and under

*Source: 2009 Annual Report of the Chef Medical Officer (80% of rare diseases are estimated to be genetic)

what is Jeans for genes day?

Thousands of children and adults pay £1 / £2 to wear their jeans to school or work on Jeans for Genes Day

Our supportersToday, we have a database of 100,000 supporters from work places to schools across the UK.

How we spend donationsAll of the net income raised by Jeans for Genes each year is distributed amongst charities

dedicated to supporting individual genetic disorders.

These charities provide vital care and support services for affected children and families, as well as ongoing research into these conditions.

Projects funded in 2010Chronic Granulomatous Disorder ResearchTrust

We help to fund a variety of projects including a psychological supportservice and CGD clinical nurse specialists.

Genetic Alliance UK A coordinator for families living with Sydrome Without a Name (SWAN).

Great Ormond Street Hospital Children's Charity

Jeans for Genes supports several research projects each year, from PhDresearch grants to ongoing work by senior academics at the Jeans forGenes Centre for Inherited Diseases.

Headlines Craniofacial Support Jeans for Genes is funding a workshop with horses. Gentle and non-judgemental, the animals will also help the children develop their non-verbal communication.

Ichthyosis Support Group Jeans for Genes is giving the ISG a grant towards its national conference.Families can meet and know they're not alone. And the children can seeothers who look like them.

International Costello Syndrome Support Group

We're proud to be helping families with Costello syndrome cometogether for the very first time in the UK at their first annual retreat.

Klinefelter's Syndrome AssociationBoys and men can have low self confidence because of the differences intheir bodies and they can find social situations difficult. We are fundingan activity weekend; which will make a dramatic difference to how boysand young men feel about themselves.

Myasthenia Gravis AssociationWith our help, the MGA are setting up an outreach programme. One ofits key aims will be to help families get the educational support theirchildren need and are entitled to at school.

The Primary Immunodeficiency AssociationCurrently projects include a five year research programme at OxfordUniversity and the Oxford Radcliffe Hospitals and comprehensive supportand advocacy activities for children and adults.

The Society for Mucopolysaccharide DiseasesJeans for Genes provides funding to the MPS Society each year. It'sinvested in research to find treatments for some of the 21 different MPSconditions. It also supports regional clinics for families.

Sickle Cell and Young Stroke SurvivorsWe are funding a workshop for young people. They can share theirexperiences, learn how to be healthy and their families can share theirworries.

Find out more about our work at www.jeansforgenesday.com

Help us reach our target

Buy our t-shirtsDesigned to make a difference! Buy from our webshop and you won't just look amazing, you'll feel great too, knowingthat all profits from every sale goes to Jeans for Genes.

Order 25 t-shirts or more and get 20% off the cost of your order! Order online or via our free phone number 0800 9804800.

www.jeansforgenes.com/webshopLimited edition women's t-shirt design for 2010 modeled

by Amanda Holden and Amber Le Bon Our white branded t-shirts modeled by

Leighton Denny and Jenny Frost

Buy or sell our stickersFifi Forget-Me-Not and her friends in Flowertot Garden are back!

This year they're helping to raise money for Jeans for Genes with a range of brand new glittery stickers.

Order a box and sell them at your school, club, workplace or just to friends and family. 40 sheets per box.

www.jeansforgenes.com/webshop

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Celebrity supporters

2010 Fashion press coverage

REACH = 91,632,874*(includes broadcast and online)

REACH: 26,349,114* including TV, radio, Newspapers, magazines

2010 campaign press coverage

Thank youwww.jeansforgenesday.com