Plymouth, MI 48170

Phone (734) 737-0532

Karen Sanders

Objective Chemist

Education Win. 2009-June 2010 Eastern Michigan University Ypsilanti, MI

Master of Science

• Master’s level chemistry coursework and research experience.

Fall 2002-Fall 2008 Eastern Michigan University Ypsilanti, MI

Bachelor of Science (Dual Major)

• Professional Chemistry with American Chemical Society

Certification

• History Major/Biology Minor

• Honors College Graduate

• Winter 2008: “Outstanding Accomplishment in Chemistry Award”

1999-2001 Oakland Community College Farmington Hills, MI

• Applied Science

Experience June 2008-Dec. 2009 Eastern Michigan University Ypsilanti, MI

Research Chemist

• Primary research focuses on the synthesis of a Plasminogen

Activator Inhibitor-1 (PAI-1) inhibitory molecule.

• Earned 16 research credit hours consisting of 30-40 hours of

laboratory work per week over the course of two years.

Aug. 2002- Aug. 2005 Stanton and Associates Belleville, MI

Assistant Manager

• Serve Safe Certified

• Implemented scheduling for 40 plus staff.

• Trained new employees including shift managers.

• Implemented profit and loss statements and ordered store supplies.

Software Beilstein, Cambridge’s Chem-draw, Sci-finder, Wavefunction’s Spartan, Excel,

Word, Access, PowerPoint, Graphical Analysis, and Refworks.

Publications and

Presentations

Coauthor on an in-progress research article that will be submitted to a high-

impact peer reviewed chemistry journal within 4 months. The article concerns

the design, synthesis, and assessment of PAI-1 inhibitors.

Characterization of a Novel Class of Polyphenolic Inhibitors of

Plasminogen Activator Inhibitor-1 Jacqueline M. Cale1‡, Shih-Hon Li1‡, Mark

Warnock1, Enming J. Su1, Paul R. North2, Karen L. Sanders2, Maria M.

Puscau2, Cory D. Emal2, and Daniel A. Lawrence1 2010 J. Bio. Chem. 285 (11)

7892-7902. 1Department of Internal Medicine, Division of Cardiovascular Medicine,

University of Michigan Medical School, 7301 MSRB III, 1150 W. Medical

Center Drive, Ann Arbor MI, 48109-0644, and 2Department of Chemistry, 225

Mark Jefferson, Eastern Michigan University, Ypsilanti, MI 48197.

2010 National Meeting and Exposition of the American Chemical Society

San Francisco, CA – 03/24/10

Structure-Activity Relationships of Sulfonamide and Ester-Based

Inhibitors of Plasminogen Activator Inhibitor-1.

Karen L. Sanders, Nadine C. El-Ayache, Gregory A. Abernathy1, Melinda S.

Meyers1, Paul R. North

1, Shih-Hon Li

2, Mark Warnock

2, Daniel A. Lawrence

2,

Cory D. Emal1.

1 Chemistry Department, Eastern Michigan University,

Ypsilanti, MI 48197. 2 Department of Internal Medicine, University of

Michigan Medical School, Ann Arbor, MI 48109-0644.

2010 Eastern Michigan University Graduate Symposium

Ypsilanti, MI – 03/24/10

Examination of the Structure-Activity Relationships of Inhibitors of

Plasminogen Activator Inhibitor-1.

Karen L. Sanders1, Hasina Saraha

1, Mark Warnock

2, Daniel A. Lawrence

2,

Cory D. Emal1.

1 Chemistry Department, Eastern Michigan University,

Ypsilanti, MI 48197. 2 Department of Internal Medicine, University of

Michigan Medical School, Ann Arbor, MI 48109-0644.

2009 Eastern Michigan University Symposium

Ypsilanti, MI – 03/27/09

Design, Synthesis, and Evaluation of Polyphenolic Inhibitors of

Plasminogen Activator Inhibitor-1.

Karen L. Sanders1, Kristi L. Henricks

1, Melinda Meyers

1, Mark Warnock

2,

Daniel A. Lawrence2, Cory D. Emal

1.

1 Chemistry Department, Eastern

Michigan University, Ypsilanti, MI 48197. 2 Department of Internal Medicine,

University of Michigan Medical School, Ann Arbor, MI 48109-0644.

Sanders, Karen. “Sustainable Trade in Pre-Colonial Asante” (Senior Thesis).

Eastern Michigan University Honors College. 2008.

Interests Skydiving, culinary arts, astronomy, and traveling.

Working Knowledge of the following Instruments and Organic Synthesis Techniques

`Jeol 400 MHz 1H/13C NMR spectrometer, Shimadzu FTIR 84005, Varian Saturn 3800-2000

GC/MS, Buck HPLC, Buck 210 AAS, Schimadzu GC-14 with FID, Rotavapor R-3000, recrystallization,

column chromatography, flash chromatography, and thin-layer chromatography. I also have a limited

working knowledge of the following: Jasco FP-6300 Spectroflurometer, SMDE model 303A differential

pulse polarography, Perkin-Elmer Lambda UV-VIS, Cary 83 laser-Raman spectrophotometer, calorimetry,

gravimetry, and coulometry.

My research has utilized several organic reaction techniques including the following: Suzuki

coupling, hydrogenation, hydrolysis, esterification, and the placement and removal of various protective

groups including benzyl, methyl, and Boc groups. On a more mechanical note I have also had experience

building a Schlenk line and setting up distillation, vacuum distillation, condensation, and reflux apparatus

and would look forward to assisting in the development of a research laboratory from scratch.