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GCE A/L Genetics & Cellcycle
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W.B.K.HETTIARACHCHIW.B.K.HETTIARACHCHI
ENDWhat is Replication?.What is Replication?.
In replication Two identical daughter DNA In replication Two identical daughter DNA molecules are made from a single DNA molecules are made from a single DNA
molecule.molecule.
This is an uneque feature in DNA.This is an uneque feature in DNA.
No other biological molecule do so.No other biological molecule do so.
W.B.K.HETTIARACHCHI
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Two coplementary polynecleotide strands are joined by hydrogen bonds
To make a DNA molecule.
W.B.K.HETTIARACHCHI
END During replication the following steps are occurred.
1. DNA molecule unwind
2. The hydrogen bonds between complementary base pairs break
3. Two strands are separated from each other
4. Each single strand act as a template for a new complementary strand.
5. Complementary nucleotides are assembled alongside each strand.
6. Sugar-phosphate backbone is formed by phosphodiester bonds between adjacent nucleotides
7. Once this had occurred along the whole length of the each strand two identical molecules of DNA are formed.
W.B.K.HETTIARACHCHI
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Hydrogen bonds break
Two strands separate
1 2
W.B.K.HETTIARACHCHI
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Complementary bases assemble alongside each strand
W.B.K.HETTIARACHCHI
END Each strand make their complementary strand
W.B.K.HETTIARACHCHI
ENDTwo identical DNA molecules are
formed
W.B.K.HETTIARACHCHIW.B.K.HETTIARACHCHI
END
Let us animate the Let us animate the process of process of replicationreplication
W.B.K.HETTIARACHCHI
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W.B.K.HETTIARACHCHI
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H bonds break Two strands seperate
W.B.K.HETTIARACHCHI
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Sugar phosphate backbone is made by joining the adjcent nucleotides ( DNA polymarase enzyme( ) )
Nucleotides with Complementary bases are assembled alongside each strands
W.B.K.HETTIARACHCHI
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Two identical DNA molecules are formed
