Lesson # 14

Molecular Genetics

DNA Replication

◦ All DNA molecules need to be doubled o replicated in order for the cell to be able to make 2 nuclei out of one.

◦ Each nucleus must receive the same number of DNA molecules.

◦ Takes place during Interphase (Phase S)

At a molecular level

• Semiconservative replication.

• The two complimentary DNA strands separate.

• Free-floating nucleotides join to their complimentary bases through hydrogen bonds.

• Each strand serves as a template for the formation of a new complimentary strand.

• The new strand forms in direction n 5’ 3’

• As a result: 2 identical DNA molecules with an old strand and a newly formed strand.