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This power point is from Joe's presentation on October 11, 2013.
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WELCOME WELCOME
Joe Keil www.whenjustsaynodoesntwork.com 920-323-2354
How do we win
How do we win
a war on drugs
a war on drugs
that we have
that we have
lost for the past
lost for the past
40+ years?40+ years?
PREVENTION!
PREVENTION!
UNITED STATES HAS ? of UNITED STATES HAS ? of the WORLD POPULATIONthe WORLD POPULATION
CONSUMES ? % of the Worlds CONSUMES ? % of the Worlds ILLEGAL DRUGSILLEGAL DRUGS
STA
TS
STA
TS
NYC consumes 10 tons of illegal drugs NYC consumes 10 tons of illegal drugs each dayeach day
121 Million Scripts for Hydrocodone in 121 Million Scripts for Hydrocodone in 20122012
20% of people who take Benadryl become 20% of people who take Benadryl become stimulated stimulated
Illegal Drug Business is a 400 billion Illegal Drug Business is a 400 billion marketmarket
Meth: 2011 MS 2096, TN 1687, ID 1437 Meth: 2011 MS 2096, TN 1687, ID 1437 and KY 1188and KY 1188
20% of people in US using pills for no 20% of people in US using pills for no reasonreason
More people are using Pills than Cocaine, More people are using Pills than Cocaine, Heroin, Hallucinogens and Inhalants Heroin, Hallucinogens and Inhalants COMBINEDCOMBINED
2010 2.4 million people tried Marijuana for 2010 2.4 million people tried Marijuana for the first timethe first time
2010 2.2 million tried pain pills for the first 2010 2.2 million tried pain pills for the first time time
Trivia Trivia
Question:Question:
What does RX mean?
What does RX mean?
In 2
001 C
hange
In 2
001 C
hange
in V
ital S
igns
in V
ital S
igns
Respirations
RespirationsHeart rateHeart rateBlood pressure
Blood pressureBody temperature
Body temperature Big Change: PAIN was
Big Change: PAIN was
added added
6 T
ypes
of
Dru
gs
6 T
ypes
of
Dru
gs
OTCOTCRX Prescription
RX PrescriptionRX Controlled
RX Controlled Controlled Illegal
Controlled Illegal Street Drugs
Street DrugsDesigner Drugs
Designer DrugsHerbal Herbal
Types
of
Dru
g
Types
of
Dru
g
Use
Use
Experimentation: Trying
Experimentation: Trying
a substance by choice
a substance by choice
or by peer pressure
or by peer pressure Abuse: using a drug to
Abuse: using a drug to
get highget high
Addiction: When the
Addiction: When the
physical harm to your
physical harm to your
body and your life no
body and your life no
longer matters!
longer matters!
EYE EXAM and Drug InfluenceEYE EXAM and Drug InfluenceIII-1
M-U-R-D-E-R-S, I-N-C, IM-U-R-D-E-R-S, I-N-C, I
VI-3A
The Eleven Systems of The Eleven Systems of Human Physiology: Human Physiology: Murders, Murders,
Inc. IInc. IM is for Muscular SystemU is for Urinary SystemR is for Respiratory SystemD is for Digestive SystemE is for Endocrine SystemR is for Reproductive SystemS is for Skeletal System
I is for Integumentary systemN is for Nervous System*C is for Circulatory System*I is for Immune System VI-3B
Muscular SystemMuscular System The body has three different The body has three different
kinds of muscleskinds of muscles
The heart, or cardiac muscleThe heart, or cardiac muscle
Smooth muscles, which control Smooth muscles, which control the body’s involuntary the body’s involuntary operationsoperations
Striated muscles, which carry Striated muscles, which carry out our voluntary movementsout our voluntary movements
Urinary SystemUrinary System• This system consists of two This system consists of two
kidneys, the bladder, ureters kidneys, the bladder, ureters connecting the kidneys to the connecting the kidneys to the bladder, and the urethra, bladder, and the urethra, which transports the urine out which transports the urine out of the bodyof the body
• Kidneys filter waste or Kidneys filter waste or harmful products, such as harmful products, such as drugs and their metabolites, drugs and their metabolites, from the blood, and dump from the blood, and dump these waste products into the these waste products into the bladder. bladder. What the Hell is a What the Hell is a metabolite?metabolite?
Respiratory SystemRespiratory System The major parts of the Respiratory System The major parts of the Respiratory System
are the lungs and the diaphragmare the lungs and the diaphragm
The diaphragm is a smooth muscle that The diaphragm is a smooth muscle that draws the air into the lungs and forces it draws the air into the lungs and forces it outout
Lungs take oxygen and transfer it to the Lungs take oxygen and transfer it to the blood, and remove carbon dioxide and blood, and remove carbon dioxide and some other waste products from the some other waste products from the blood, and expel them into the outside air blood, and expel them into the outside air
Digestive SystemDigestive SystemMajor components of this system are the Major components of this system are the
tongue, teeth, esophagus, stomach, tongue, teeth, esophagus, stomach, intestines, liver and pancreasintestines, liver and pancreas
The Digestive System breaks down large The Digestive System breaks down large particles of food, until they are of a size particles of food, until they are of a size and chemical composition that can be and chemical composition that can be absorbed in the bloodabsorbed in the blood
Endocrine SystemEndocrine System• The Endocrine System is made up of a The Endocrine System is made up of a
number of different glands, that secrete number of different glands, that secrete hormoneshormones
• Hormones are complex chemicals that Hormones are complex chemicals that travel through the blood stream and that travel through the blood stream and that control or regulate certain body processescontrol or regulate certain body processes
• Some drugs can mimic the effects of Some drugs can mimic the effects of hormones, or can react with the hormones hormones, or can react with the hormones in ways that alter the hormones’ effectsin ways that alter the hormones’ effects
Reproductive SystemReproductive System The functions of the The functions of the
Reproductive System fall into Reproductive System fall into two roles 1. Self producing two roles 1. Self producing (cytogenic) 2. Hormone (cytogenic) 2. Hormone producing (endocrinic)producing (endocrinic)
We are primarily concerned We are primarily concerned with hormone production with hormone production since the hormones produced since the hormones produced by the Reproductive System by the Reproductive System aid the nervous system in its aid the nervous system in its regulatory roleregulatory role
Skeletal SystemSkeletal SystemConsists of bones, cartilage and ligamentsConsists of bones, cartilage and ligaments
The Skeletal System provides support to The Skeletal System provides support to the body, permits movement, and forms the body, permits movement, and forms blood cellsblood cells
It is however, affected by drug abuse, we It is however, affected by drug abuse, we just may not be able to see it just may not be able to see it
19811982 1985 My Prom Date
Integumentary SystemIntegumentary SystemConsists of skin, hair, finger and toe nails, Consists of skin, hair, finger and toe nails,
and accessory structuresand accessory structures
The chief functions of the Integumentary The chief functions of the Integumentary System include protection of the body, System include protection of the body, control of body temperature, excretion of control of body temperature, excretion of wastes (i.e. through the sweat) and wastes (i.e. through the sweat) and sensory perceptionsensory perception
Outside Temperature 14Outside Temperature 14
Nervous SystemNervous System This system consists of the brain, This system consists of the brain,
the brain stem, the spinal cord and the brain stem, the spinal cord and the nervesthe nerves
Nerves keep the brain informed of Nerves keep the brain informed of changes in the body’s external and changes in the body’s external and internal environmentsinternal environments
Nerves also carry messages from Nerves also carry messages from the brain to the body’s muscles, the brain to the body’s muscles, tissues and organstissues and organs
The Nervous System controls, The Nervous System controls, coordinates and integrates all coordinates and integrates all physiological process, so the normal physiological process, so the normal body functions can be maintainedbody functions can be maintained
Circulatory SystemCirculatory System
• For our purposes, the Circulatory For our purposes, the Circulatory System consists of the heart, the System consists of the heart, the blood vessels (veins and arteries), blood vessels (veins and arteries), and the bloodand the blood
• Blood carries food, water, oxygen, Blood carries food, water, oxygen, hormones, antibodies etc. to the hormones, antibodies etc. to the tissues and organstissues and organs
• Blood also carries heat through the Blood also carries heat through the bodybody
• Blood is the main carrier that Blood is the main carrier that brings drugs to the brainbrings drugs to the brain
• The heart pumps and forces the The heart pumps and forces the blood to circulate through the bodyblood to circulate through the body
IMMUNE SYSTEMIMMUNE SYSTEM The immune system protects against The immune system protects against
disease by destroying “foreign” cells and disease by destroying “foreign” cells and by inactivating toxins and other foreign by inactivating toxins and other foreign chemicals with its antibodies.chemicals with its antibodies.
HomeostasisHomeostasis• The human body is exposed to constantly The human body is exposed to constantly
changing changing externalexternal environment. environment.• Changes are neutralized by theChanges are neutralized by the internal internal
environment – the bloodenvironment – the blood• Oxygen, foods, water and other Oxygen, foods, water and other
substances are constantly leaving body substances are constantly leaving body fluids to enter cells, while carbon dioxide fluids to enter cells, while carbon dioxide and other wastes are leaving the cells to and other wastes are leaving the cells to enter these fluidsenter these fluids
• Yet the chemical composition of these Yet the chemical composition of these fluids remains within very narrow limitsfluids remains within very narrow limits
• This phenomenon is called homeostasisThis phenomenon is called homeostasis
Homeostasis: is the key to drug use: the Homeostasis: is the key to drug use: the body is out of balancebody is out of balance
Dynamic balance or steady state involving levels of salts, water, sugars and other material
in the body’s fluidsVI-3D
When y
our
sick
When y
our
sick
You take meds to put
You take meds to put
your body back into
your body back into balancebalanceWhen you take drugs
When you take drugs
to get high it is done
to get high it is done
to put your body out
to put your body out
of balance to feel high
of balance to feel high
or feel good.
or feel good.
The Male Brain compared to the The Male Brain compared to the Female BrainFemale Brain
Seriously
Seri
ousl
y Seri
ousl
y
Addin
g E
TO
H t
o
Addin
g E
TO
H t
o
Date
Nig
ht
Date
Nig
ht
Afferent
Sensory Nerves
Motor Nerves
Efferent
Voluntary Autonomic
Parasympathetic Sympathetic
Afferent
Sensory Nerves
Motor Nerves
Efferent
Voluntary Autonomic
Parasympathetic Sympathetic
Fundamental NotionsFundamental Notions If something interferes with the messages to If something interferes with the messages to
the brain sent along the motor nerves, the the brain sent along the motor nerves, the brain’s control over the heart, the lungs, the brain’s control over the heart, the lungs, the muscles and other organs will be distortedmuscles and other organs will be distorted
If something interferes with the messages If something interferes with the messages the brain receives from the sensory nerves, the brain receives from the sensory nerves, the brain’s perception of the outside world the brain’s perception of the outside world and of the body’s status will be distortedand of the body’s status will be distorted
THIS IS HOW DRUGS WORK ON THE THIS IS HOW DRUGS WORK ON THE FUNCTIONING OF THE NERVOUS SYTEMFUNCTIONING OF THE NERVOUS SYTEM
Motor NervesMotor Nerves• There are two sub-systems of motor There are two sub-systems of motor
nerves:nerves:– The The voluntary nervesvoluntary nerves send messages to the send messages to the
striated muscles that we consciously controlstriated muscles that we consciously control
– The The autonomic nervesautonomic nerves send messages to the send messages to the muscles and organs that we do not consciously muscles and organs that we do not consciously control, i.e., smooth muscle and cardiac musclecontrol, i.e., smooth muscle and cardiac muscle
The Autonomic Sub-SystemThe Autonomic Sub-System
• The Autonomic Sub-System divides into The Autonomic Sub-System divides into two groups:two groups:– First, the First, the Sympathetic nervesSympathetic nerves command the command the
body to react in response to fear, stress, body to react in response to fear, stress, excitement, etc.excitement, etc.• ““Fight or Flight” Responses:Fight or Flight” Responses:
– Blood pressure elevatedBlood pressure elevated
– Pupils to dilatePupils to dilate
– Sweat glands to activateSweat glands to activate
– Hair to stand on endHair to stand on end
– Heart beat to increase and strengthenHeart beat to increase and strengthen
– Blood vessels of the skin to constrictBlood vessels of the skin to constrict
– Inhibited digestionInhibited digestion
The Autonomic Sub-SystemThe Autonomic Sub-System• Second, the Second, the Parasympathetic nervesParasympathetic nerves carry carry
messages that produce relaxed and messages that produce relaxed and tranquil activitiestranquil activities– Pupils to constrictPupils to constrict
– Heartbeat to slowHeartbeat to slow
– Peripheral blood vessels to dilatePeripheral blood vessels to dilate
– Blood pressure to decreaseBlood pressure to decrease
– Digestion to be facilitatedDigestion to be facilitated
Drugs & the Autonomic Sub-Drugs & the Autonomic Sub-SystemsSystems
• Some drugs mimic the neurotransmitters Some drugs mimic the neurotransmitters that travel in the Sympathetic and that travel in the Sympathetic and Parasympathetic nerve systemsParasympathetic nerve systems
• Drugs that mimic neurotransmitters in the Drugs that mimic neurotransmitters in the Sympathetic system are called Sympathetic system are called SympathomimeticSympathomimetic drugs. These drugs will drugs. These drugs will artificially create the same effects.artificially create the same effects.
• Drugs that mimic neurotransmitters in the Drugs that mimic neurotransmitters in the Parsympathetic system are called Parsympathetic system are called ParasympathomimeticParasympathomimetic drugs. These drugs drugs. These drugs will artificially create the same effects. will artificially create the same effects.
A Simplified Concept of a A Simplified Concept of a NerveNerve
The nerves that carry messages The nerves that carry messages to and from the brain often are to and from the brain often are pictured as “wires” or “telephone pictured as “wires” or “telephone wires” that carry electrical signalswires” that carry electrical signals
A more accurate, but still A more accurate, but still simplified concept would envision simplified concept would envision a nerve as a series of broken wire a nerve as a series of broken wire segments, with the segments segments, with the segments separated by short spaces, or separated by short spaces, or gapsgaps
Simple Concept Simple Concept of a Nerveof a Nerve
How does this affect How does this affect your health?your health?
The a
bso
rbti
on
and e
limin
ati
on o
f dru
gs Alcohol is a fixed rate
at ?Drugs are ½ lives What is a half life and
how does it work?
½ li
ves
Lets say a drugs half
life is 5 hoursThat simply means every 5 hour half of the drug is gone
Therefore the first 5 hours the majority of
the drug is gone or half of it. There are usually
about 8 half lives
ADDITIVE EFFECT
Effect Effect
1 + 1 = reinforced 1
NULL EFFECT
No Effect No Effect
0 + 0 = 0
OVERLAPPING EFFECT
No Effect Effect
0 + 1 = 1
ANTAGONISTIC EFFECT
Effect OppositeEffect
1 + -1 = ????