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Dr. Satti M. SalehChief of Infectious Diseases
DepartmentMedical Director MGH
ISOLATION PRECAUTIONS IN HOSPITAL
Rationale for precautionsInfection Transmission Requires :
Microorganism
Source
Susceptible Host
Means of transmission.
SOURCEPatient , personnel , visitors .Acute cases in incubation .Colonized Patients .Endogenous Flora .Inanimate Environment
( contaminated ) eg; water , food , equipment .
ISOLATION PRECAUTIONS IN HOSPITALs
HOSTAge Underlying diseaseTreatment : 1 -Antimicrobial. 2 – Corticosteroids. 3 – Immunosuppressive agents.Weak in first line of defense mechanisms eg; Surgical
operations . Anesthesia . Catheters .
ISOLATION PRECAUTIONS IN HOSPITALS
Transmission Its main routes : Contact a -Direct contacts. b - Indirect contacts. c - Droplet transmission ( 3 feet ). Common vehicle transmission Water equipment devices. Airborne transmission. Airborne droplet nuclei ( 5 micrometers or small ) Evaporated droplets or dust particles eg TB ,
Measles , chickenpox. Vector borne.
ISOLATION PRECAUTIONS IN HOSPITALS
Interruption of transmission of micro-organisms is directed primarily at transmission.
Disadvantages of isolation. Special equipment, environmental
modification , more cost. Patient care may be affected. Deprives patient of normal social
relationship. Disadvantages to be weighed against
prevention values .
Early isolation practices .
ISOLATION PRECAUTIONS IN HOSPITALS
1877 Separate facilities. 1910 Cubical system, separate gown , wash hands,
disinfect objects. 1950 Infectious disease hospital begin to close. 1960 T.B Hospitals decreased. 1970 CDC Isolation manual. 1983 CDC Guidelines. 1 - Category specific isolation. Disease specific isolation. Use guidelines to develop a system . 2- Encourage personnel to make decision on what
precautions to be taken. 3 – Encourage personnel to make decision about the
likelihood of exposure to reduce costs.
ISOLATION PRECAUTIONS IN HOSPITALS
CATEGORY SPCIFIC ISOLATION Strict isolation Contact isolation. Respiratory isolation T.B isolation. Enteric precaution Drainage , secretion precautions. Blood & body fluid precautions. Protective isolation. DISEASE SPECIFIC ISOLATION
ISOLATION PRECAUTIONS IN HOSPITALS
Consider epidemiology of each infectious disease.
Highly educated. To be updated. Universal precautions ( 1985 ) : Applying blood & body fluid precautions
universally to all people. Prevention of needle stick injuries. Traditional barriers e.g gloves . Eye coverings in certain procedures .
Amniotic ,CSF, semen, & vaginal secretions. Not to feces, nasal secretions, sputum,
sweat, &tears.
ISOLATION PRECAUTIONS IN HOSPITALS
Body substance isolation ( 1987 ): Isolation of all moist &potentially infectious
body substances ( blood, urine, feces, sputum, saliva, wound drainage, other body fluids regardless of their presumed infection status ).
Stop sign alert (( airborne )). DISADVANTAGES : Added costs. Overprotection of personnel. Difficulty in maintaining routine application. Lack of hands washing after gloves removal. Droplet infection.
ISOLATION PRECAUTIONS IN HOSPITALS
New Isolation Guidelines ( 1990 ) : Problem of multi-drug resistance T.B. Multi-drug resistant of micro organisms. New guidelines should : 1- Be epidemiologically sound . 2- Recognize importance of all body
secretions. 3- Adequate precautions of airborne, droplets
contact routes. 4- Simple. 5- Use new terms to avoid confusions. 6- In expensive
New Isolation Precautions, 1996
’‘Standard’’And
’‘Transmission – Based Precautions’’
ISOLATION PRECAUTION IN HOSPITALS
HICPAC Isolation Precautions (1996 ) 1 – Standard precautions a - Blood b - All body fluids c - Non intact skin d - mucous membranes. ( to reduce transmission from organized &
unorganized source of infection.) 2- Transmission based precautions : ( patient documented or suspected to be infectious) a - Airborne precautions b - Droplet precautions c - Contact precautions. ( may be combined for diseases with multiple route of
transmission).
STANDARD PRECAUTIONS
Consider all patients and their bodily fluids (except sweat) to be potentially infectious
Use appropriate barrier precautions when there is a risk of exposure to blood, body fluids, secretions, excretions, mucous membranes and non-intact skin.
Patients with known or suspected infections are NOT to have their medical records labeled as “infectious”.
Specimens of patients with known or suspected infections are NOT to be labeled as “infectious”. All specimens are to be treated in the same safe manner .
Used needles and sharps should be disposed of safely ( in puncture proof sharp boxes ) .
Needles should NOT be recapped . All Health care workers should receive the HBV vaccine .
Transmission-Based Precautions
.Three categories of Transmission-based Precautions:
-Contact Precautions. - Droplet Precautions.
-Airborne Precautions .
AIRBORNE TRANSMISSION
Airborne spreads upon aerosolization of small particles (=< 5 micron) of the infectious agent that can then travel over long distances through the air .
Most common nosocomial pathogens transmitted by this route :
- Mycobacterium tuberculosis .- Varicella-zoster virus (chickenpox) .- Measles .- Smallpox.- ? SARS .
AIRBORNEPRECAUTIONS
Place the patient in a negative pressure room with at least 6 – 12 air exchanges per hour .
Room exhaust must be appropriately discharged outdoors or passed through a HEPA ( high – efficiency particulate aerator ) filter before recirculation within the hospital .
The door of the room should be kept closed .
DROPLET TRANSMISSION
Respiratory droplets are large particles (>5 micron) expelled during .
- Coughing .- Sneezing .- Talking.- During procedures such as suctioning and
bronchoscope . Droplets travel < 1,5 meter from the source patient . Example :• Neisseria meningitides .• Haemophilus influenza type b ( invasive ) .• Streptococcus pyogenes (group A Streptococcus) . • Mycoplasma pneumonia .
DROPLET PRECAUTIONS
Private room preferred; cohorting allowed if necessary.
Special air handling and ventilation are unnecessary .
The door of the room may remain open .
Wear a mask when within 1 meter of the patient .
Mask the patient during transport .
DROPLET TRANSMISSION
Respiratory droplets are large particles (>5 micron) expelled during .
- Coughing .- Sneezing .- Talking.- During procedures such as suctioning and
bronchoscope . Droplets travel < 1,5 meter from the source patient . Example :• Neisseria meningitides .• Haemophilus influenza type b ( invasive ) .• Streptococcus pyogenes (group A Streptococcus) . • Mycoplasma pneumonia .
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
TB Transmission
TRANSMISSION Requires
1)Pt’s Hands of health care workers .
2)Survive for several minutes .3)Non or Inadequate hand hygiene .4)Contaminated Hands Pt’s
ISOLATION PRECAUTION IN HOSPITALS
Air borne precautions : Dissemination of droplet nuclei . Small particle residue of 5 micrometers or less of
evaporated droplets. Suspended on the air for long time. Dust particles containing the infectious agents. Special air handling & ventilation required e.g measles
, varicella , TB . Droplet precautions : Large particles droplets Invasive HI type b. Invasive N Meningitides. Diphtheria , Mycoplasma , sterptococcal infection. Viral infections : adenovirus , mumps, rubella .
ISOLATION PRECAUTIONS IN HOSPITALS
Contact precautions : Patient known or suspected to have serious
illness transmitted by contact. a - GIT, Respiratory , skin or wound infection
with multi drug resistant bacteria or colonization.
b – Enteric infections : shigella, HIV, E.coli, O157, 117 .
c – Respiratory viruses . d – Skin infections Diphtheria , Herpes,
Cellulitis Scabies , VHF.
Phlebotomy Handbook: Blood Collection Essentials, Seventh Edition
Diana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Herpes
Neonatal infection with herpes simplex virus type 1, showing ulcerating and
vesicular skin lesions .Lesions may be present in small numbers .The virus was transmitted during birth .
ISOLATION PRECAUTIONS IN HOSPITALS
Additional Emperic Precautions : Diarrhea Enteric organism contact Vesicular rash Varicella air borne Maculopapular rash measles air borne cough, fever, upper lobe infilterate TB air borneRisk of multi drug resistant bacteria contact Abscess draining wound strept, staph contact
FUNDAMENTAL OF ISOLATION PRECAUTIONS 1- Hand washingAfter touching blood , body fluid….etcAfter removing glovesBetween pt’s contact.
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Standard Precautions
Figure 5.9 Rinse Hands in a Downward Motion with Water
ISOLATION PRECAUTIONS IN HOSPITALS
2- Gloves : a – for touching blood, body fluid …etc. b – Mucous membranes . c – contaminated items d- a septic procedures .
3 - Patient placing: a - Private room. b - Hand wash & other facilities. c - With appropriate room mate ( cohorting ). d - Private room with appropriate ventilation e.g T.B.
4- Transport of infected patients : a – limit movement . b – Appropriate measure if needed .
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Standard Precautions
Figure 5.11 Supplies for Isolation Procedures
Phlebotomy Handbook: Blood Collection Essentials, Seventh Edition
Diana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
ISOLATION PRECAUTIONSIN HOSPITALS
c – Notify other departments. d – Patient education.
5 – Mask respiratory, Eye precautions , Eye shields.
6 – Gowns , boots, shoe covers, leg coverings ( remove gown before leaving). .
7 – Environmental control .
8- linen9- proper waste disposal ( e.g sharp)
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Standard Precautions
4 .Face shields
Figure 5.18 Face shields or goggles may be worn
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Standard Precautions
Specific Isolation Techniques and
Procedural Steps .2Gowning
Figure 5.13 Gowns should be large enough to cover all clothing
Phlebotomy Handbook: Blood Collection Essentials, Seventh EditionDiana Garza • Kathleen Becan-McBride
Pearson EducationCopyright 2005
Standard Precautions
5 .Completing the protection
Figure 5.19 Gloves should be pulled over the ends of gown sleeves
Precautions Needed for Cases
Condition Type Duration Pulmonary TB S+A Till sputum
Negative Chicken Pox S+A Till rash crusted M-meningitis S+D 24 Hrs HIV S Duration of stay
Clinical Syndromes: Empiric precautions as per clinical
presentation
THANK YOU
Dr. Satti Mohammed