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HOW CELLS EXPORT
PROTEINS IN THE
MEMBRANE AND
RESEARCHERS VISUALIZA
OCURRING mRNA
María Camila Foronda
Campuzano
Medicine Student
INTRODUCTION
The structure of a ribosome complexinvolved in a protein process
By a wonderful technique they
vizualized mRNA and associated
molecules
How Cells Export And Embed Proteins In The Membrane
The
ribosomes found on
the RE fabric proteins
that are
export outside cell
The proteins move
from the ER and accu
mulated
near the Golgi appar
atus and
How Cells Export And Embed Proteins In The Membrane
The Proteins
are "eliminated"
from membrane
in vesicles by
channels
How Cells Export And Embed Proteins In The Membrane
• Transduction of external
signals produces a resp
onse from the target
cell
• This response is impaired
as a
result of activation or
inhibition of a metaboli
c pathway
How Cells Export And Embed Proteins In The Membrane
• An international team of researchers to find another
mystery related to the riboso
mes -
the enigmatic jumbles of
molecules
• the journal Nature, could help
in developing new
antibiotics to combat multi-
resistant superbugs such as MRSA(methicillin-
resistant Staphylococcus aure
us infection) found inmany U.S
. hospitals
ANOTHER
STUIDES…
OBSERVATION
Thisinvestigacionsraises that the
complexribosome-
protein and thereceptor act as a
«switch», so itcan stop
They raisesto that it more
studiesproductionsof proteins
can be controled
It couldindicated tothe stop of
manydeseases
In Scientific First, Researchers
Visualize Naturally Occurring
mRNA• Messenger
RNA, the key
intermediary in
gene
expression, tra
nslating the
DNA's genetic
code into the
amino acids
that make upproteins
In Scientific First, Researchers
Visualize Naturally Occurring mRNA
• There
are 20 amino-
acids forming sub-
units for
proteins while
only four nucleic
bases are used to
construct the RNA
or DNA
In Scientific First, Researchers
Visualize Naturally Occurring mRNA
• The mature mRNA is transport
ed to the cytoplasm of the
cell, in the case
of eukaryotes beings through
nuclear membrane pores
Messenger RNA in
the cytoplasm is coupled to t
he ribosomes
In Scientific First, Researchers
Visualize Naturally Occurring mRNA
• mRNA are the machiner
y responsible for protein
synthesis.After a
certain amount of time
the mRNA is
degraded into its
component nucleotides
, usually with the
assistance of
ribonucleases
OBSERVATION
It is animportant
study becausethey are in theway to control
gene expressions
This control can cure
manydesease with
geneticorigin
It is a useful
techniqueto
monitoredmRNA
MEDICAL UTILITY
Both studies can
be very benefical
for discover
deseases and try
to find a cure for
it, because
molecular
biology is basis of
all functions of
our bodies
BIBLIOGRAPHY
• MARTINEZ S, Lina Maria. Biologia
Molecular. 6 ed. Medellin. UPB.
Fac Medicina, 2011. 34p.
• ScienceDaily, Your source for the
latests research news, United
States.[Index].