ThinkAirbnb
PhilipE.Bourne,PhD,FACMITheNationalInstitutesofHealth
http://www.slideshare.net/[email protected]
Bonazzi &Bourne2017,PLOSBiology,InPress
TheStateofPlayforNGSandBeyond
• Dataandanalyticsaresiloed• Dataarecomplexandbeinggeneratedatexponentialrates(?)• Computemustmovetothedata• ThinkingFAIRisdifferentfrombeingFAIR• Currentpracticesareinefficient• Reproducibilityismythical(perhapsevenwiththerighttools)• Incentivestodobetterareminimalbutgrowing
ExamplesfrommyOwnWork
Ittookseveralmonthstoreplicatethisworkthiswork
…Andjustlastweek…
Phew…
http://www.sdsc.edu/pb/kinases/
ToolsFixThisProblemRight?
• ExtractedallPMCpaperswithassociatedJupyter notebooksavailable• Approx 100• Tookarandomsampleof25• Only1ranoutofthebox• Severalranwithminormodification• Otherslackedlibraries,sufficientdetailstorunetc.
Ittakesmorethantools..Ittakesincentives…
DanielMietchen2017PersonalCommunication
Iamnotcrazy,hearmeout
• Airbnbisaplatformthatsupportsatrusted relationshipbetweenconsumer(renter)andsupplier(host)• Theplatformfocusesonmaximizingtheexchangeofservicesbetweensupplierandconsumerandmaximizingtheamountoftrustassociatedwithagivenstakeholder• Itseemstobeworking:• 60millionuserssearching2millionlistingsin192countries• Averageof500,000stayspernight.• EvaluationofUS$25bn
Isnotbiomedicalresearchthesame?
WhyacomparisontoAirbnbisnotfair
•Airbnbwasborndigital
• TheexchangeofservicesonAirbnbaresimplecomparedtowhatisrequiredofaplatformtosupportbiomedicalresearch
Neverthelessthereismuchtobelearnt
PaperAuthor PaperReader
DataProvider DataConsumer
Employer Employee
ReagentProvider ReagentConsumer
SoftwareProvider SoftwareConsumer
GrantWriter GrantReviewer
Supplier Consumer Platform
MSProjectGoogleDriveCoursera
ResearchgateAcademia.eduOpenScienceFrameworkSynapseF1000Rio
Educator Student
Platforms- TheSituationToday
Insummarythereisnotcurrentlyawidelyadoptedsingleplatformfortheexchangeofservicesinbiomedicalresearch.Eitherthereisaplatformperserviceornoplatformatall. Whyhavewenotdonebetterandwhataretheimpedimentstoday?
Impedimentstoabiomedicalplatform
•Currentworkpracticesbyallstakeholders• Entrenchedbusinessmodels• Sizeoftheundertakingakaresourcesneeded• Trust• Incentivestousetheplatform
http://www.forbes.com/sites/johnhall/2013/04/29/10-barriers-to-employee-innovation/#8bdbaa811133
TheNIHthroughtheBigDatatoKnowledge(BD2K)andothersareexperimentingwithaplatform,keepinginmindtheneedtoovercometheseimpediments
EnterTheCommons
https://en.wikipedia.org/wiki/Ealing_Common#/media/File:Ealing_Common_-_geograph.org.uk_-_17075.jpg
PaperAuthor PaperReader
DataProvider DataConsumer
Employer Employee
ReagentProvider ReagentConsumer
SoftwareProvider SoftwareConsumer
GrantWriter GrantReviewer
Supplier Consumer Platform
MSProjectGoogleDriveCoursera
ResearchgateAcademia.eduOpenScienceFrameworkSynapseF1000Rio
Educator Student
Commons–Initialfocusisonintegratingtwolayersofthescholarlyworkflow
CommonsTopology
ComputePlatform:CloudorHPC
Services:APIs,Containers,Indexing,
Software:Services&Tools
scientificanalysistools/workflows
Data“Reference”DataSetsUserdefineddata
DigitalObjectCom
pliance
Appstore/UserInterface
PaaS
SaaS
IaaS
https://datascience.nih.gov/commons
“IreallyadmireAirbnbasapioneerofthesharingeconomyandforbuildingcommunity.They'vefoundanelegantwaytohelphostsmakemoremoneyandforgueststohaveauthenticexperiences.Itbringsthosepeopletogetherinauniqueway.“
LoganGreen
“TheCommonsisoneeffortatcreatingasharingeconomyandforbuildingcommunity.Wehopeforamorecosteffectiveandproductiveresearchenvironmentwhilebringingpeopletogetherinauniqueway.“
PhilBourne
Acknowledgements
• VivienBonazzi,JennieLarkin,MichelleDunn,MarkGuyer,AllenDearry,Sonynka Ngosso,TonyaScott,LisaDunneback,Vivek Navale (CIT/ADDS)
• NLM/NCBI:MikeHuerta,GeorgeKomatsoulis• NHGRI:Valentina diFrancesco
• NIGMS:SusanGregurick
• CIT: DebbieSinmao,AndreaNorris
• NIHCommonFund:JimAnderson,BetsyWilder,LeslieDerr
• NCICloudPilots/GDC:WarrenKibbe,TonyKerlavage,Tanja Davidsen
• CommonsReferenceDataSetWorkingGroup:Weiniu Gan (HL),AjayPillai(HG),ElaineAyres,(BITRIS),SeanDavis(NCI),VinayPai (NIBIB),MariaGiovanni(AI),LeslieDerr (CF),ClaireSchulkey (AI)
• RIWGCoreTeam:RonMargolis(DK),IanFore,(NCI),AlisonYao(AI),ClaireSchulkey (AI),EricChoi(AI)
• OSP: DinaPaltoo,KrisLanglais,ErinLuetkemeier,AgnesRooke,
Bonazzi &Bourne2017,PLOSBiology,InPress