Superiorwound
closure
1. Chee SP. Clear corneal incision leakage after phacoemulsification–detection using povidone iodine 5%. Case Report. Int. Ophthalmology 2005 Aug-Oct:26:175-179.
2. Mifflin MD, Kinard, K, et al. Comparison of Stromal Hydration Techniques for Clear Corneal Cataract Incisions: Conventional Hydration versus Anterior Stromal Pocket Hydration. Journal of Refractive Surgery. 2012 Jun; 38(6):933-937.
3. Herretes S, Stark WJ, et al. Inflow of ocular surface fluid into the anterior chamber after phacoemulsification through sutureless corneal cataract wounds. American Journal of Ophthalmology. 2005;140;737-740.
4. Masket S, Hovanesian J, et al. Use of a calibrated force gauge in clear corneal cataract surgery to quantify point-pressure manipulation. J Cataract Refract Surg. 2013 Feb 21.
0%
20%
40%
60%
80%
100%
Spontaneous leak Spontaneous or with minimal touch
(ч0.25 ozf)
50.0%(244/488)
76.0%(371/488)
Cumulative leak rates prior to device placement*
Clear corneal incisions leak
Propensity for leakage has been demonstrated in several additional studies.1-4
Challenges or forces on the eye, such as touching or sneezing, may promote leaks.
More protection should be administered for vulnerable wounds.
Superior to sutures for prevention of wound leaks
0%
10%
20%
30%
40%
ReSure Sealant Suture
Per protocol leak rates following device placement*
4.1%(12/295)
34.1%(60/176)
p<0.0001
Significantly fewer adverse events in the ReSure group vs. the suture group (p<0.0001).
94.1% of sealant cases were rated “easy” or “very easy” to use.
No safety concerns were reported.
Patients were comfortable overall.
* ReSure Sealant Pivotal Clinical Trial results. Ocular Therapeutix Inc., data on file.
Effectively seals clear corneal incisions
Safe and comfortable for the patient
36 Crosby Drive, Ste. 101Bedford, MA 01730
www.ocutx.com
Customer service: 877-628-8998
ReSure is a registered trademark of Ocular Therapeutix, Inc. © 2014 Ocular Therapeutix, Inc. All rights reserved.
ML 079 Rev B
Clinical Use in Cataract Surgery
ReSure Sealant is indicated for intraoperative management of clear corneal incisions (up to 3.5mm) with a demonstrated wound leak for which a temporary dry surface can be achieved, in order to prevent postoperative fluid egress from such incisions following cataract surgery with intraocular lens (IOL) placement in adults.
Cataract Patients withPrevious Ocular Surgeries
Post-refractiveRK*LASIK*PRK*
Post-glaucoma filteringTrabeculectomy*Tube shunt*
Standard Cataract Surgery Suture replacement*Incisions up to 3.5 mmLeaky wounds (temporarily dried)Visible internal/external gapeIrregular/asymmetric woundsHigh myopesCorneal ectasia (keratoconus)*Phaco burn*Patients at Risk for Eye Trauma
Mentally disabled*Patients in assisted livingElderly
High-Risk Cataract Patients MRSA*Monocular*Diabetic*Immunocompromised*Undergoing chemotherapy*Long-term systemic steroids*
Premium Cataract Patients ToricMultifocalAccommodatingFemtosecond*
Combination Cataract(when cataract surgery is performed first)
MIGS*Pars Plana Vitrectomy** Not evaluated in the ReSure Sealant pivotal clinical trial
For more information, visit www.resuresealant.com.
Product
ReSure SealantReSure Sealant
Product Number
RS-1004-US-5RS-1004-US-10
Units per Box
510
Complex Cataract CasesSmall pupil
Iris hooks*Malyugin ring*
Capsular tension ring*Dense cataractLens explant/exchange*