ISSN 0036-807512 JULY 1996VOLUME 273NUMBER 5272 SCIENCE AMERICAN

AssOCIATION FORTHEADVANCEMENT OFSCIENCE

NEWSThe Decline of German UniversitiesForeign Students Bypassing Germany

Disputed Results Now Just a Footnote

Panel Backs Joint Bion Mission

Earmark for New Ship Puts AcademicsOver Pork Barrel

Italian Bioethics: Embryo ReportOpens Old Wounds

Publisher Draws Censorship Charge

Tobacco Studies: UC Objects toResearch Restrictions

Silver Thread Boosts Current Capacity

Unruly Sun Emerges inSolar Observatory's First ResultsSpying On the Sun-on the Cheap

Evolutionary and Systematic BiologistsConverge

Twinkle, Twinkle, Little Quasar

THIS WEEK IN SCIENCE

EDITORIALScientific Imagination and IntegrityK. J. Ryan

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LETTERS 165Not the "Dark Ages": W. C. Barker and R. S. Ledley* Dinosaurs and Their Youth: M. A. Norell andJ. M. Clark; N. R. Geist and T. D. Jones * TobaccoResearch: J. F. Glenn; J. Cohen; T. D. Sterling *

Uninterrupted Electric Power: D. N. Baker and J.G. Kappenman

SCIENCESCOPE 171

Protein Matchmaker May LeadNew Gene Therapy to the Altar

RANDOM SAMPLES 191High Court Won't Review Hopwood * ManateeKiller Revealed * Canada Considers Gene Law

BOOK REVIEWS 196Bendectin and Birth Defects, reviewed by S.Bartlett Foote * The Mismeasure of Man * TheWorld According to Wavelets * Wavelets * Vignette* Books Received

PRODUCTS & MATERIALS 262

SCIENCE'S NEXT WAVE 265Bioinformatics: New Frontier Calls Young Scien-tists

r 183

SPECIAL NEWS REPORTPutting Prions to the TestFlipping YeastPrusiner and the Press

184186188

PERSPECTIVESIf a Tree Falls in the Forest... 201M. Keller, D. A. Clark, D. B. Clark, A. M.Weitz, E. Veldkamp

The Shrewd Grasp of RNA r 202PolymeraseR. Landick and J. W. Roberts

Rho Returns: Its Targets in Focal O 203AdhesionsH. Bussey

ARTICLENew Designs of MacroporousPolymers and Supports: From Separationto BiocatalysisF. Svec and J. M. J. Frechet

205

MWOWWWWWWW AAAS Board ofRita R. ColwellRetiring President, Chairman

Jane LubchencoPresident

Mildred S. DresselhausPresident-elect

Directors __Sheila JasanoffWilliam A. Lester Jr.Simon A. LevinMarcia C. LinnMichael J. NovacekAnna C. RooseveltJean E. TaylorNancy S. Wexler

William T. GoldenTreasurer

Richard S. NicholsonExecutive Officer

* SCIENCE (ISSN 0036-8075) is published weekly on Friday, except the last week inDecember, by the American Association for the Advancement of Science, 1200 New YorkAvenue, NW, Washington, DC 20005. Periodicals Mail postage (publication No. 484460) paid atWashington, DC, and additional mailing offices. Copyright © 1996 by the American Association forthe Advancement of Science. The title SCIENCE is a registered trademark of the AAAS. Domesticindividual membership and subscription (51 issues): $102 ($55 allocated to subscription). Domesticinstitutional subscription (51 issues): $250. Foreign postage extra: Mexico, Caribbean (surface mail)$55; other countries (air assist delivery) $90. First class, airmail, student, and emeritus rates onrequest. Canadian rates with GST available upon request, GST #1254 88122. Printed in the U.S.A.

SCIENCE * VOL. 273 * 12 JULY 1996

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Section of a mural (dated 700 A.D.) found in an archeo-logical site at Cacaxtia, Mexico [under protection of theInstituto Nacional de Antropologia e Historia (INAH)].The quetzal (70 centimeters, head to tail) is painted withMaya blue dye, a dye first discovered at Mayan sites. It is

.COVER

a mixture of clay, indigo, and metal particles in a silicatesubstrate. The clay and indigo form a superlattice, andscattered metal particles disperse light, producing thislong-lasting blue color. See page 223. [Photo: Autho-rized reproduction of the INAH, under its responsibility.]

RESEARCH ARTICLE

Transcription Processivity: VI 21 1

Protein-DNA Interactions HoldingTogether the Elongation ComplexE. Nudler, E. Avetissova, V. Markovtsov, A.Goldfarb

REPORTS

Compression of Ice to 2 0 Gigapascals: 218

Infrared Evidence for a SymmetricHydrogen-Bonded PhaseA. F. Goncharov, V. V. Struzhkin, M. S.Somayazulu, R. J. Hemley, H. K. Mao

220Making DNA AddF. Guarnieri, M. Fliss, C. Bancroft

Maya Blue Paint: An Ancient 223Nanostructured MaterialM. Jos6-Yacamdn, L. Rend6n, J. Arenas, M. C.Serra Puche

Formation of Atomically Flat Silver 226Films on GaAs with a "Silver Mean"Quasi PeriodicityA. R. Smith, K.-J. Chao, Q. Niu, C.-K. Shih

Mechanism of Suppression of 228Cell-Mediated Immunity by Measles VirusC. L. Karp, M. Wysocka, L. M. Wahl, J. M.Ahearn, P. J. Cuomo, B. Sherry, G. Trinchieri,D. E. Griffin

Structure of the Amino-Terminal 231Core Domain of the HIV- Capsid ProteinR. K. Gitti, B. M. Lee, J. Walker, M. F. Summers,S. Yoo, W. I. Sundqulist

Polar Overdominance at the Ovine 236callipyge LocusN. E. Cockett, S. P. Jackson, T. L. Shay, F.Farnir, S. Berghmans, G. D. Snowder, D. M.Nielsen, M. Georges

Structure of the FKBP 1 2-Rapamycin P' 239Complex Interacting with Binding Domainof Human FRAP

J. Choi, J. Chen, S. L. Schreiber, J. Clardy

Long-Term Lymphohematopoietic 242Reconstitution by a Single CD34-Low/Negative Hematopoietic Stem CellM. Osawa, K.-i. Hanada, H. Hamada, H. Nakauchi

Regulation of Myosin Phosphatase by F 245Rho and Rho-Associated Kinase (Rho-Kinase)K. Kimura, M. Ito, M. Amano, K. Chihara, Y.Fukata, M. Nakafuku, B. Yamamori, J. Feng, T.Nakano, K. Okawa, A. Iwamatsu, K. Kaibuchi

Bipartite Ca2'-Binding Motif in 248C2 Domains of Synaptotagmin andProtein Kinase CX. Shao, B. A. Davletov, R. B. Sutton, T. C.Sudhof, J. Rizo

Platelet-Mediated Lymphocyte Delivery 252to High Endothelial VenulesT. G. Diacovo, K. D. Puri, R. A. Warnock, T.A. Springer, U. H. von Andrian

TECHNICAL COMMENTS

On Catching Fly Balls 256J. L. Dannemiller, T. G. Babler, B. L. Babler; T.M. Jacobs, M. D. Lawrence, K. Hong, N. GiordanoJr., N. Giordano Sr.; M. K. McBeath, D. M.Shaffer, M. K. Kaiser

252Homing to thelymph nodes

O Indicates accompanying feature X0 -XChange of address: allow 4 weeks, giving old and new addresses and 8-digit account number.Postmaster: Send change of address to Science, P.O. Box 1811, Danbury, CT 06813-1811.Single copy sales: $7.00 per issue prepaid includes surface postage; bulk rates on request.Authorization to photocopy material for internal or personal use under circumstances not fallingwithin the fair use provisions of the Copyright Act is granted by AAAS to libraries and other users

registered with the Copyright Clearance Center (CCC) Transactional Reporting Service, providedthat $4.00 per article is paid directly to CCC, 222 Rosewood Drive, Danvers, MA 01923. Theidentification code for Science is 0036-8075/83 $4.00. Science is indexed in the Reader's Guide toPeriodical Literature and in several specialized indexes.

On the WebBioinformatics As a Careerhttp://sci.aaas.org/nextwave/niches-bioinformatics/

SCIENCE * VOL. 273 * 12 JULY 1996

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273 (5272)

(5272), 157-263.273Science 

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