CURRICULUM VITAE
(1) PERSONAL DATA:
Name : Dr. Mohamed Farouk Elshal
Current position : Professor of Biochemistry, Molecular Biology
Department, Genetic Engineering and
Biotechnology Research Institute, University of
Sadat City, Egypt
Linked In : https://www.linkedin.com/in/prof-mohamed-
farouk-elshal-a9b3b926
Google Scholar : https://scholar.google.com/citations?user=yOwFHk0AAAAJ&hl=en
Date of birth : 23 / 02 / 1971
Place of birth : Mansoura – Egypt
Marital status : Married
E-mail : [email protected]
Tel : (+2) 0502349040
Mobile : (+2) 01021279933 / 0114885910
(2) EDUCATOIN
1988-1992 B.Sc. in Chemistry, Faculty of Science - Mansoura University - EGYPT
1992-1993 Diploma in Computer System-Analysis and Software Programming,
Computer Center, Mansoura University – EGYPT
1993-1996 M.Sc. in Biochemistry, “Quantitative Analysis of Cellular DNA-Content
using Flow Cytometry“. Faculty of Science, Mansoura University – EGYPT
1997-2001 Ph.D. in Biochemistry and Molecular biology, “Utilization of Flow
Cytometry in the Assessment of Genetic Abnormalities in gastrointestinal
disorders“. Faculty of Science, Mansoura University – EGYPT
(3) WORK EXPERIENCE:
1992-1995 Research Assistant, Chemistry Department, Mansoura University, Egypt.
1995-2000 Clinical Biochemistry specialist; Flow cytometry unit, Biotechnology Research
Department, Gastroenterology Center, Mansoura University – Egypt.
2000-2001 Assistant Lecturer of Biochemistry, Genetic Engineering and Biotechnology
Research Institute (GEBRI), Menoufiya University – Egypt.
2001–2006 Lecturer of Biochemistry, Molecular Biology Department, (GEBRI), Menoufiya
University – Egypt.
2006-2008 Assistant Professor of Biochemistry at Molecular Biology Department, Head of
Flow Cytometry Unit, Genetic Engineering And Biotechnology Research Institute
(GEBRI), University of Sadat City – Egypt.
Mohamed Farouk Elshal, Ph.D.
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2008-2015 Associate Professor at Biochemistry Department, Faculty of science, King
Abdulaziz University, Jeddah, KSA.
2015-till now Professor of Biochemistry at Molecular Biology Department, Head of Flow
Cytometry Unit, Genetic Engineering And Biotechnology Research Institute
(GEBRI), University of Sadat City – Egypt.
(4) INVITED PROFESSIONAL APPOINTMENTS
2001-2004 Lecturer of Immunology, Zoology Department, Faculty of Science,
Menoufiya University – Egypt.
2006- 2007 Visiting Assistant Professor of Biochemistry, Biochemistry Division,
Chemistry Department, Faculty of Science, Mansoura University-
Egypt.
2008-2015 Visiting Associate Professor of Biochemistry, Biochemistry
Department, Faculty of Science, King Abdulaziz University, Jeddah,
KSA.
(5) POST-DOCTORAL FELLOWSHIP:
2004-2006 Post-Doctoral Research Fellow, National Heart, Lung, and Blood
Institute, National Institutes of Health, Bethesda, Maryland, USA.
(6) WORKSHOPS AND FACULTY TRAINING COURSES:
1. Computer Sciences and software programming, Computer Center, Mansoura
University 1/2/1992 to 4/2/1993.
2. Flow Cytometry and imaging techniques Training Course, Ain Shams University –
Cairo, Egypt from 21-23 October 1998.
3. Applications of Flow Cytometry in Clinical Practice Training Course, Cairo
University, National Cancer Institute – Cairo, Egypt, from 13-18 October 1998.
4. “Teaching Staff Preparation Course”, Faculty of Education, Menoufiya University,
Egypt. 2000
5. “Faculty & Leadership Development Project training courses” FLDP-project -
Minoufiya University, Feb. 2006 to June 2006.
6. “Faculty & Leadership Development Project training courses”, Sadat City University,
Egypt from July to August 2015.
(7) RESEARCH AND DEVELOPMENT
1. Head of Flow Cytometry Research Unit, at GEBRI, Sadat City University to assist
researchers and postgraduate students.
2. Cofounder of Immunology Unit, at King Fahd Medical Research Center, King
Abdulaziz University, Jeddah – KSA.
Mohamed Farouk Elshal, Ph.D.
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3. Cofounder of Stem Cells Research Unit, at King Fahd Medical Research Center,
King Abdulaziz University, Jeddah – KSA.
(8) PUBLICATIONS:
1. Abdel-Moneim M. Osman, Huda M. Al-Kreathy, Amal Al-Zahrani, Osama A. Ahmed,
Wafaa S. Ramadan, Mohamed F. ElShal, Samir E. Al-Harthi, Ahmed S. Ali and
Lateef M. Khan. Enhancement of Efficacy and Reduced Toxicity of Cisplatin
Through Self Nanoemulsifying Drug Delivery System (SNEDDS). Int. J.
Pharmacol., 2017, DOI: 10.3923/ijp.2017.
2. Mohamed SA, Elshal MF, Kumosani TA, Aldahlawi AM, Basbrain TA, Alshehri FA,
Choudhry H. L-Asparaginase Isolated from Phaseolus vulgaris Seeds Exhibited
Potent Anti-Acute Lymphoblastic Leukemia Effects In-Vitro and Low
Immunogenic Properties In-Vivo. International Journal of Environmental
Research and Public Health. 2016 Oct 14;13(10):1008.
3. Elshal MF, Aldahlawi AM, Saadah OI, McCoy JP. Expression of CD200R1 and its
ligand CD200 on T-helper lymphocytes of pediatric patients with ulcerative
colitis and Crohn's disease. Clinical Laboratory 2016,62(8) (DOI:
10.7754/Clin.Lab.2016.151231).
4. Foda AA, Zalata KR, Elshal MF. Genetic dissimilarity between primary colorectal
carcinoma and their lymph node metastases: Ploidy, p53, Bcl-2 and c-myc
expression. Pathology. 2016 Feb 1;48:S124.
5. Mohamed F. Elshal, Kaleemuddin M., Alia M. Aldahlawi, Omar Saadah, J. Philip
McCoy. Altered expression of CD200R1 on dendritic cells of patients with
inflammatory bowel diseases: in silico investigations and clinical evaluations.
BMC Genomics 2016, 17(Suppl 6):P29.
6. Mohamed M. Abdel-aziz, Mohamed F. Elshal, Aymn T. Abass, Sherif El-Kafrawy,
Sameera Ezzat, Mohamed Abdel-Wahab A. Comparison of AFP-L3 and p53
antigen concentration with alpha-fetoprotein as serum markers for hepatocellular
carcinoma. Clin Lab. 2016;62(6):1121-9.
7. Mohamed SA, Elshal MF, Kumosani TA, Mal AO, Ahmed YM, Almulaiky YQ, Asseri
AH, Zamzami MA. Heavy Metal Accumulation is Associated with Molecular
and Pathological Perturbations in Liver of Variola louti from the Jeddah Coast of
Red Sea. Int J Environ Res Public Health. 2016 Mar 21;13(3). pii: E342.
8. Alia M. Aldahlawi, Mohamed F. Elshal, Laila A. Damiaiti, Laila H. Damanhori, Sami
M. Bahlas. Analysis of CD95 and CCR7 expression on circulating CD4+
lymphocytes revealed disparate immunoregulatory potentials in systemic lupus
erythematosus. Saudi Journal of Biological Sciences, Volume 23, Issue 1,
January 2016, Pages 101–107.
9. Zalata KR, Elshal MF, Foda AA, Shoma A. Genetic dissimilarity between primary
colorectal carcinomas and their lymph node metastases: ploidy, p53, bcl-2, and
c-myc expression—a pilot study. Tumor Biology. 2015 Aug 1;36(8):6579-84.
Mohamed Farouk Elshal, Ph.D.
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10. Osman, A. M., Al-Zahrani, A., Al-Harthi, S. E., El-Hanafy, A. A., Elashmaoui, H. M.,
& Al-Kreathy HM, Ramadan WS, Elshal, M. F. Enhancement of efficacy and
reduced toxicity of cisplatin through self nanoemulsifying drug delivery system
(SNEDDS). Molecular Medicine Reports. (In press).
11. Elshal MF, Aldahlawi AM, Saadah OI, McCoy JP. Reduced Dendritic Cells Expressing
CD200R1 in Children with Inflammatory Bowel Disease: Correlation with Th17
and Regulatory T Cells. Int J Mol Sci. 2015 Dec 4;16(12):28998-9010.
12. Rasha M. Saleh, Walaa F. Awadin, Reham A. El-Shafei, Yousef Y. Elseady, Faheim E.
Wehaish and Mohamed F. Elshal. Cardioprotective role of tadalafil against
cisplatin-induced cardiovascular damage in rats. European Journal of
Pharmacology. Eur J Pharmacol. 2015 Sep 14. pii: S0014-2999(15)30247-8. doi:
10.1016/j.ejphar.2015.09.015.
13. Saleh A. Mohamed, Mohamed F. Elshal, Taha A. Kumosani, and Alia M. Aldahlawi.
Purification and Characterization of Asparaginase from Phaseolus vulgaris
Seeds, Evidence-Based Complementary and Alternative Medicine, Volume 2015
(2015), Article ID 309214
14. Murad HA, Habib H, Kamel Y, Alsayed S, Shakweer M, Elshal M. Thearubigins
protect against acetaminophen-induced hepatic and renal injury in mice:
biochemical, histopathological, immunohistochemical, and flow cytometry
study. Drug Chem Toxicol. 2015 Aug 3:1-9.
15. Zalata, K. R., Elshal, M. F., Foda, A. A., & Shoma, A. (2015). Genetic dissimilarity
between primary colorectal carcinomas and their lymph node metastases: ploidy,
p53, bcl-2, and c-myc expression-a pilot study. Tumour Biol. 2015
Aug;36(8):6579-84. doi: 10.1007/s13277-015-3353-y
16. Alia M. Aldahlawi, Mohammed F. Elshal, Fai T. Ashgan, Sami Bahlas, Chemokine
receptors expression on peripheral CD4-lymphocytes in rheumatoid arthritis:
Coexpression of CCR7 and CD95 is associated with disease activity, Saudi
Journal of Biological Sciences, Volume 22, Issue 4, July 2015, Pages 453–458.
17. Osman AM, Telity SA, Damanhouri ZA, Al-Harthy SE, Al-Kreathy HM, Ramadan WS,
Elshal MF, Khan LM, Kamel F. (). Chemosensitizing and nephroprotective
effect of resveratrol in cisplatin -treated animals. Cancer Cell Int, 2015, 15, 6.
doi: 10.1186/s12935-014-0152-2
18. Osman, A. M., Al-Malki, H. S., Al-Harthi, S. E., El-Hanafy, A. A., Elashmaoui, H. M.,
& Elshal, M. F. (2015). Modulatory role of resveratrol on cytotoxic activity of
cisplatin, sensitization and modification of cisplatin resistance in colorectal
cancer cells. Mol Med Rep. doi: 10.3892/mmr.2015.3513.
19. Mohamed F. Elshal, Alia M. Aldahlawi, Arwa A. Zehairy. Studying modulatory
effects of Prostaglandin E2 on dendritic cells-induced apoptosis by breast cancer
cells. Life Sci J 2014;11(10):155-162.
Mohamed Farouk Elshal, Ph.D.
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20. Mohamed F. Elshal, Taha A. Kumosani, Essam I. Azhar, Alia M. Aldahlawi.
Quantification of circulating endothelial and progenitor cells as biomarkers for
dengue virus infection. Life Sci J 2014;11(10):250-256.
21. Faheim E. Wehaish, Yousef Y. Elseady, Rasha M. Saleh and Mohamed F. Elshal.
Molecular and Immunohistochemical Evidences for Cardiovascular Damage in
Addition to Renal Toxicity of Cisplatin in Rats. Life Sci J 2014;11(6):1-8
22. Aldahlawi AM, Elshal MF: Differentiation of Monocyte Isolated from Leukocyte
Depletion Filters into Immature Dendritic Cells Resistant to Stimulation with
Lipopolysaccharide. Life Science Journal 2013;10(4): 2542-2547.
23. Mohamed F. Elshal, Abdulrahman L. Almalki, Hussein K Hussein and Jalal A. Khan:
Synergistic antiosteoporotic effect of Lepidium Sativum and alendronate in
glucocorticoid-induced osteoporosis in Wistar rats. Afr J Tradit Complement
Altern Med. 2013; 10(5):267-273.
24. Abdel-MoneimM Osman, Ohoud M Al-Orabi, Mohamed F ElShal, Wafaa Saad El-
Din, Mohamed N. Alaama, Huda M. Al-Kerathy, ZoheirA Damanhouri and et
al. Chemosensetizing and cardioprotective effects of resveratrol in doxorubicin-
treated animals. Cancer Cell International 2013, 13:52 doi:10.1186/1475-2867-
13-52
25. Elshal, Mohamed F.; Bernawi, Amna E.; Al-Ghamdy, Maryam A.; et al. The
association of bone mineral density and parathyroid hormone with serum
magnesium in adult patients with sickle-cell anaemia, Archives of Medical
Science Volume: 8 Issue: 2 Pages: 270-276 Published: APR 2012. DOI:
10.5114/aoms.2012.28554.
26. Abdel-Moneim M Osman, Hadeel M Bayoumi, Sameer E Al-Harthi, Zoheir A
Damanhouri and Mohamed F ElShal. Modulation of doxorubicin cytotoxicity
by resveratrol in a human breast cancer cell line. Cancer Cell International 2012,
12:47. DOI:10.1186/1475-2867-12-47.
27. Elshal MF, Kumosani TA. Abulnaja KO. Influence of defatted flaxseed diet on insulin
sensitivity, vascular permeability and lipid profile in a rat model of type 2
diabetes mellitus. Journal of Medicinal Plants Research, 2012 Vol. 6(11):2188-
2193.
28. Damanhouri. L H., Al-Sakkaf. K.A, Elshal. M.F. The relationship between
Erythropoietin and adiponectin and the inflammatory cytokines. Life Sc. J. 2012,
9(4):5121-27.
29. Mohamed F. Elshal, Mohamed Abdel Salam and Jalaluddin A. Khan. n vitro
cytotoxicity and induction of apoptosis by multiwalled carbon nanotubes in
human peripheral lymphocytes: Correlation with physicochemical properties.
African Journal of Biotechnology Vol. 11(52), pp. 11455-11462, 28 June, 2012.
DOI: 10.5897/AJB11.4082.
Mohamed Farouk Elshal, Ph.D.
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30. Abu-Zinadah OA, Hussein HK, Elshal MF and Elnaggar MH. Effect of excess dietary
copper on proliferation and differentiation of the proerythroblasts and
erythrocytes in rats. African Journal of Biotechnology, 2012 Vol. 11 (22):6187-
6191.
31. Maha M. Al-Bazi, Mohamed F. Elshal, Samir M. Khoja. Reduced coenzyme Q10 in
female smokers and its association with lipid profile in a young healthy adult
population. Arch Med Sci 2011;7,6:948-954. DOI: 10.5114/aoms. 2011.26605.
32. El-Far, Mohamed; Elshal, Mohamed; Refaat, Manar; et al.Antitumor activity and
antioxidant role of a novel water-soluble carboxymethyl chitosan-based
copolymer. Drug Development and Industrial Pharmacy Volume: 37:1481-1490
Published: DEC 2011. DOI:10.3109/03639045.2011.587430.
33. Jalal JA, Elshal MF, Qari MH, Al-Gamdy MA, Bernawi AE. Hypoparathyroidism and
hypocalcemia in sickle cell disease: correlation with bone turnover markers and
bone mineral density. Journal of Appplied Hematology 2011 (2): 34-40.
34. El-Far M, Elshal M, Refaat M, El-Sherbiny IM. Antitumor activity and antioxidant role
of a novel water-soluble carboxymethyl chitosan-based copolymer. Drug Dev
Ind Pharm. 2011 Dec;37(12):1481-90.
35. Jalal JA, Kumosani TA, Elshal MF: Elucidation of the possible causes in some regions
of Saudi Arabia using biochemical, microbiological, toxicological and
immunological approaches. KAU Science Bulletin, JKAU: Sci., 2010 Vol. 22
No. 1, pp: 225-238; DOI: 10.4197 / Sci. 22-1.15 2010.
36. El-Far M, Elshal MF, Bondock S, Refaat M. Preclinical biochemical studies using a
novel 5-aminolevulinic acid ester derivative with superior properties for
photodynamic therapy of tumors. International Journal of Medicine and Medical
Sciences Vol. 1(7) pp. 278-287, July, 2009.
37. Elshal MF, Abdelaziz A, Abbas A, Mahmoud K, Fathy H, Mongy SE, El-Basyuoni S,
Ahmed H, McCoy P. Quantification of circulating endothelial cells in peripheral
blood of systemic lupus erythaematosus patients: a simple and reproducible
method of assessing endothelial injury and repair. Nephrol Dial Transplant.
Nephrol Dial Transplant. 2009 May;24(5):1495-9.
38. Elshal MF, El-Sayed IH, Elsaied MA, El-Masry SA, Kumosani TA. Sperm head
defects and disturbances in spermatozoal chromatin and DNA integrities in
idiopathic infertile subjects: Association with cigarette smoking. Clin Biochem.
2009 May;42(7-8):589-94.
39. Kumosani TA, Elshal MF, Al-Jonaid AA, Abduljabar HS. The influence of smoking on
semen quality, seminal microelements and Ca(2+)-ATPase activity among
infertile and fertile men. Clin Biochem. 2008 41(14-15):1199-203.
Mohamed Farouk Elshal, Ph.D.
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40. Elshal MF, Khan SS, Raghavachari N, Takahashi Y, Barb J, Bailey JJ, Munson PJ,
Solomon MA, Danner RL, McCoy JP Jr. A unique population of effector
memory lymphocytes identified by CD146 having a distinct immunophenotypic
and genomic profile. BMC Immunol. 2007 Nov 13;8:29.
41. Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, Nguyen AT, Malide
D, Combs CA, Hall G, Zhang J, Raffeld M, Rogers TB, Stetler-Stevenson W,
Frank JA, Reitz M, Finkel T. Human mesenchymal stem cells exert potent
antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med. 2006 May
15; 203(5):1235-47.
42. Elshal MF, McCoy JP. Multiplex bead array assays: Performance evaluation and
comparison of sensitivity to ELISA. Methods. 2006 Apr;38(4):317-23.
43. El-Saied MA, Abdelaziz AM, Elkholy AM, Elshal MF: Effect of PUFA and NB-UVB
on the profiles of activated T-Lymphocytes in peripheral blood of patients with
Psoriasis Vulgaris. Egypt. J. Derm. Androl. 2006 26 (2): 65-74.
44. M A Elsaied, M F Elshal, N M Dawoud, I H El-Sayed, S El-Masry: Lipid Peroxidation
and Antioxidant Enzymes in Infertile Men: Correlation with Sperm Chromatin
Structure Assay. J. Pan-Arab League of Dermatologists Vol. 17, No. 1, February
2006
45. Elshal MF, Khan SS, Takahashi Y, Solomon MA, McCoy JP. CD146 (Mel-CAM), an
Adhesion Marker of Endothelial Cells, is a Novel Marker of Lymphocyte Subset
Activation in Normal Peripheral Blood. Blood. 2005 Oct 15;106(8):2923-4.
46. M A Elsaied, E A Farag, M F Elshal and Y E Youssef. Sperm Chromatin Structure
Assay in Varicocele Patients. J. Pan-Arab League of Dermatologists Vol. 16,
No. 1 : 141-149, February 2005
47. M. F. Elshal, J P McCoy. The detection of circulating angiogenic and vasculogenic
cells by flow cytometry. J. Clin. Ligand Assay 2004; 3:163-169.
48. M. F. Elshal, Y. Takahashi, S. Chakrabarti, R. Srinivasan, D. Suffredini, T. Igarashi, S.
Solomon, A. Lundqvist, A. J. Barrett, J. P. McCoy, Jr, and Richard Childs.
Complex Alterations in Serum Cytokines and Increased Il-4 Levels Characterize
Patients Developing Chronic Thrombocytopenia after Allogeneic Hematopoietic
Cell Transplantation. Blood, Nov 2004; 104: 4985.
49. Moustafa Ahmed El-Saied, Hanan Fathy and M F ElShal, Flow Cytometric Study of
The Effect Of Narrow-band UVB On Epidermal Cell Cycle and Ki67 Antigen
Expression in Chronic Plaque Psoriasis. J. Pan-Arab League of Dermatologists
Vol. 15, No. 1:81-90 , February 2004.
50. Elshal MF, Elsayed IH, El Kady IM, Badra G, El-Refaei A, El-Batanony M, Hendy
OM. Role of concurrent S. mansoni infection in H. pylori-associated gastritis: a
Mohamed Farouk Elshal, Ph.D.
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flow cytometric DNA-analysis and oxyradicals correlations. Clin Chim Acta.
2004 16;346(2):191-8.
51. El-khawaga OA, Salem TA, Elshal MF. Protective role of Egyptian propolis against
tumor in mice. Clin Chim Acta. 2003 Dec;338(1-2):11-6.
52. M F. El-Refaei, T A. Salem, M.F.Elshal, and M Othman: Tannic acid potentially
inhbits tumor growth, raises survival of mice bearing syngeneic tumor. Eg. J.
Biochemistry 2003; 21:139-155.
53. S. A. Riad, A. A. Hemeida, M Osman, M.F. Elshal. Probiotic effects on gene
expression, DNA content and cell proliferation in bovans-white laying hens.
Egyptian J. Genet. Cytol., 32:317-339, July 2003.
54. M. F. Elshal, H A. Ismael, A Al-Hendy, and K El Halfawy: Heterogeneity of
spermatozoal dna in infertile men and its relationship to sperm motility and
semen quality. Eg. J. of Laboratory Medicine 2002, 14:51-64.
55. M. F. Elshal, Ibrahim H. El-sayed and Khalil El Halfawy: The Chromatin Structure
And In-Situ Denaturation Of Nuclear Dna In Sperms Of Infertile Men:
Correlation With Oxidative Stress. Eg. J. Biochemistry 2002; 235-250.
56. M Abdel-Wahab, A Abo-Elenein, O Fathy, N Gadel-Hak, M.F. Elshal, A Yassen, A
Sultan, and F. Ezzat: Does Cholecystectomy Affect Antral Mucosa? Endoscopic,
Histopathologic and DNA Flow Cytometric Study. HepatoGastroenterology
47:621-625; 2000.
57. M Abdel-Wahab, A.M. Attalah, M.F. Elshal, M.Abdel-Raouf, K.R.Zalata and F. Ezzat:
Cellular Proliferation And Ploidy of the Gastric Mucosa: The Role of
Helicobacter Pylori. Hepato-Gastroenterology 44:880-885; 1997.
58. A.M.Attalah, M.Abdel-Wahab, M.F. Elshal, K.R.Zalata, and F. Ezzat: Apoptosis in
Chronic Gastritis: Evaluation of the Gastric mucosa by DNA flow cytometry and
the Expression of the High Molecular Weight Cytokeratin. Hepato-
Gastroenterology 43:1305-1312; 1996.
59. M Abdel-Wahab, A.M. Attalah, M.F. Elshal, I Eldousoky, K.R.Zalata, N Gadel-Hak,
and F. Ezzat: Correlation between endoscopy, histopathology and DNA flow
cytometry in patients with gastric dyspepsia. Hepato-Gastroenterology 43:1313-
1320, 1996.
60. M. Attalah, H. G. Osman, M. F. Elshal, K. R. Zalata and M. Abdel-Wahab:
Quantitative analysis of cellular DNA content using Flow Cytometry: Evaluation
of the Biochemical Significance of Cellular DNA, serum Gastrin abnormalities
in Peptic Ulcer Diseases. Mans. Science Bulletin, 23:37; 1996.
Mohamed Farouk Elshal, Ph.D.
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(9) PATENTS
61. El-Far M.A., Elshal M. & El-Sherbiny I.M. (Dec. 2007). Chemically modified chitosan
as efficient anticancer agent. (UK Patent: GB-2-454-221-A).
(10) Abstracts and Posters:
62. Mohamed F. Elshal: Role of the Expression CCR7+CCR5+ CX3CR1+ CD95+/- Cells
in the Peripheral Blood Lymphocytes in Systemic Lupus Erythematous Patients.
15th International Congress of Immunology (ICI), Milan, Italy, 22 Aug - 27
Aug, 2013. Poster.
63. Mohamed F. Elshal: Impact of Systemic Lupus Erythematosus on Chemokines
Expression and Apoptosis Induction in Peripheral Blood Lymphocytes. Xth
International Congress of the Saudi Hematology Society, Madina Monwara 20-
22 December, 2011.
64. Mohamed F.Elshal: Potential Role of CD146 in Lymphocyte Transendothelial
Migration and Inflammation. The Ninth International Conference on Chemistry
and Its Role in Development ICCRD 9th -2007. Sharm Elsheikh, Egypt 16-19
April 2007.
65. Mohamed F.Elshal: Profiling of CD146 (MUC18) Circulating Endothelial Cells”. The
International Conference of Genetic Engineering and Biotechnology, Sharm El-
sheikh, Egypt 16-19 Dec. 2006, Oral Presentation.
66. Mohamed F.Elshal: Profiling of peripheral blood circulating endothelial cells”.
American Heart Association 2005 Annual Scientific Meeting: Dallas
Convention Center -Dallas, TX., USA.
67. Yoshiyuki Takahashi, Abdul Tawab, Roger Kurlander, Mohamed Elshal, Charles
Bolan, E.J. Read, Susan Leitman, J. Philip McCoy, Andreas Lundqvist, Erkut
Bahceci, and Richard Childs. AMD3100 Mobilized Apheresis Products Are
Rich in T-Cells That Do Not Undergo a Th-2 Type Cytokine Polarization:
Implications for Allografting. Blood, Nov 2005; 106: 296.
68. Lundqvist, N. Hamoui, J. Andersson, M. Elshal, Y. Takahashi, R. Srinivasan, D.
Suffredini, P. J. McCoy, Jr., and R. Childs. Allograft Cell Content and GVHD
Differ in Murine Recipients of AMD3100 Versus G-CSF Mobilized Peripheral
Blood Stem Cells. Blood, Nov 2005; 106: 3108.
69. Raghavachari, N; Khan, SS; Elshal, M; et al.Transcript profiling of peripheral blood
circulating endothelial cells. Circulation Volume: 112 Issue: 17 Pages: U275-
U276 Published: OCT 25 2005.
70. Mohamed F. Elshal: Heterogenity of Spermatozoal DNA content in Infertile Men And
Its Relationship to Sperm Motility and Semen Quality”. ESLM’S First Arab
Congress “Advanced Laboratory Technology – The Quest for the Best”; Cairo,
Egypt.
Mohamed Farouk Elshal, Ph.D.
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71. Mohamed F. Elshal: The chromatin structure and in-situ denaturation of nuclear DNA
in sperms of infertile men”. The 5th National Conference of Biochemistry and
Molecular Biology, Cairo, Egypt.
72. Mohamed F. Elshal: Cellular prolifer Helicobacter pylori”. International Health,
Alexandria, Egypt.
73. Mohamed F. Elshal: Correlation between endoscopy, histopathology and DNA flow
cytometry in patients with gastric Dyspepsia". 4th United European
Gastroenterology Week –50th Anuual Meeting of the German Society of
Gastroenterology and Metabolisim - 2th United European Gastroenterology
Meeting Gut: S2(37): 211; 1995, Berlin, Germany.
74. Mohamed F. Elshal: A study of the cellular DNA flow cytometry and the high
molecular weight cytokeratin expression in gastric epithelial cells". 4th United
European Gastroenterology Week –50th Annual Meeting of the German Society
of Gastroenterology and Metabolisim - 2th United European Gastroenterology
Meeting Gut: S2(37): 212; 1995, Berlin, Germany.
(11) THESES
75. M.F. Elshal: Utilization of Flow Cytometry in the Assessment of Genetic
Abnormalities in gastrointestinal disorders. Ph.D. Thesis, Mansoura University,
2001.
76. M.F. Elshal: Quantitative Analysis of Cellular DNA-Content using Flow Cytometry.
(Master Thesis). Mansoura University, 1996.
(12) CONFERENCES and WORKSHOPS
1. The 3rd International Genomic Medicine Conference (The 3rd IGMC, 2015),
Jeddah, KAU. Saudi Arabia.
2. Recent Advances in Flow Cytometry. The first BD Biosciences Research Users'
meeting for the Middle East region on Dec. 11 & 12, 2014 in Dubai.
3. International Genomic Medicine Conference in Saudi Arabia. Jeddah, KSA
November 24-26, 2013.
4. Xth International Congress of the Saudi Hematology Society, Madina Monwara 20-
22 December, 2011.
5. Mesenchymal Stem Cells: Sources and Potential Applications. Workshop on stem
cell will be held in March, 21st, WESTEIN HOTEL, Jeddah, KSA, February 2010.
6. The Ninth International Conference on Chemistry and Its Role in Development
ICCRD 9th -2007. Sharm Elsheikh, Egypt 16-19 April 2007.
7. The International Conference of Genetic Engineering and Biotechnology, Sharm El-
sheikh, Egypt 16-19 Dec. 2006.
8. American Heart Association 2005 Annual Scientific Meeting: Dallas Convention
Center -Dallas, TX., USA.
Mohamed Farouk Elshal, Ph.D.
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9. American Society of Hematology 46th Annual Meeting: San Diego , CA , USA .
published as an abstract in Blood (ASH Annual Meeting Abstracts), Nov 2004.
10. ESLM’S First Arab Congress “Advanced Laboratory Technology – The Quest for
the Best”; Cairo, Egypt, March 2001.
11. The 5th National Conference of Biochemistry and Molecular Biology, Cairo, Egypt,
14-16 May 2002.
12. International conference on infectious diseases and public.health, Alexandria, Egypt,
October 17-20, 1997.
(13) FUNDED PROJECTS
1. Mohamed Farouk Elshal, Jalauldin A. Khan, Khaled Omr Aboulnaja. Comparative
study between Peripheral Vascular Permeability in Diabetic and non-diabetic
hyperinsulinemia models in rats. Project No. 3-23/429 funded by Deanship of
Scientific Research, King Abdulaziz University, KSA.
2. Mohamed Farouk Elshal, Taha Koumosani, Khalid O. Abulnaja, Therapeutic
effects of some natural products extracts on lowering cardiovascular diseases risk
caused by endothelial cells dysfunction in diabetic and obese diabetic rats. Project
No. 185/428 funded by Deanship of Scientific Research, King Abdulaziz University,
KSA.
3. Jalaluldin Aazem Khan, Ahmed N. Abou-Khatwa, Mohamed Farouk Elshal.
Elucidation of the possible causes of camels’ death in some regions of Saudi Arabia
using biochemical, microbiological, toxicological and immunological approaches.
Project No. 165/428 funded by Deanship of Scientific Research, King Abdulaziz
University, KSA.
4. Mohamed Farouk Elshal, Abdulrahman O. Almalki, Comparison of the
biochemical effects of Lepidium sativum and Bisphosphonate on glucocorticoid
induced osteoporosis in adult female rats. Project No.: 3-87/428 funded by Deanship
of Scientific Research, King Abdulaziz University, KSA.
5. Jalaluldin Aazem Khan, Mohamed Abdulsalam, Mohamed Farouk Elshal,
Investigating the cytotoxic effects of carbon nanotubes on human blood
lymphocytes: A flow cytometric study. Project No. 3-107/428 funded by Deanship of
Scientific Research, King Abdulaziz University, KSA.
6. Alia M. A. Aldahlawi, Mohamed F. Elshal. Dendritic cells Generation from
Leukocytes Depleted Fraction, King Abdulaziz University- Deanship of Scientific
research, 2011.
7. Mohamed F. Elshal, Alia M. Dahlawi: Studying modulatory effects of Prostaglandin
E2 on dendritic cells-induced apoptosis by breast cancer. DSR funded project 2013.
8. Mohamed F. Elshal, Taha A. Kumosani, Essam I. Azhar, Alia M. Aldahlawi.
Quantification of circulating endothelial and progenitor cells as biomarkers for
dengue virus infection. DSR project 2013.
9. Saleh Mohamed, Mohamed Elshal: Enzymatic Approaches for Controlling Tumor
growth “Project number: 11-BIO-1516-03”, 2014.
Mohamed Farouk Elshal, Ph.D.
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10. Kaltoom Elsakaf, Mohamed Elshal, et al.,: Studying the abnormalities of the
cellular energy dependant AMP-activated protein kinase signalling pathway in
obesity and the risk of breast cancer development in Saudi Arabia “Project number:
10-BIO1255-03, 2014.
11. Mohamed F. Elshal, Alia M. Aldahlwi, Omar I. Saadah: Assessment of the
expression of CD200 and CD200r on cells from patients with inflammatory bowel
disease and their association with inflammatory markers. (DSR, KAU, KSA)
(RG/32/02), 2015.
(14) THESES SUPERVISION:
1. Rania Mostafa Sultan: Study of the immunological changes associated with some
gastrointestinal diseases using flow cytometry. Chemistry Department, Faculty
of Science, Mansoura University, 2002-2005.
2. Sherif Ghobrial: Effects of DDB , glycyrrhizin, Curcumin and their combinations on
experimentally induced-hepatic injury. Molecular Biology department, Genetic
Engineering and Biotechnology Research Institute. 2004-2007
3. Patul Redini, Response of liver and heart functions to L-Carnitine intake in a model of
nonalcoholic fatty liver disease in rats. Biochemistry Department, Faculty of
Science, King Abdulaziz University, 2008:2010.
4. Khalid Al-Ghamdi: The biochemical effects of some plant extracts on vascular
endothelial dysfunction in type II diabetic rats, Biochemistry Department,
Faculty of Science, King Abdulaziz University, 2009-2011
5. Laila Al-Domiati: Impact of systemic lupus erythemotosus on chemokines expression
& apoptosis induction in perphral blood lymphocyte. Biochemistry Department,
Faculty of Science, King Abdulaziz University, 2010-1012
6. Fae Talal: Impact of Rheumatoid Arthritis on chemokines expression & apoptosis
induction in perphral blood lymphocyte. Biochemistry Department, Faculty of
Science, King Abdulaziz University, 2010-2012
7. Abdel-Aziz Al-Oraby: Vitamin D binding protein (DBP) role in the development of
cardiovascular diseases in hemodialysis patients. Biochemistry Department,
Faculty of Science, King Abdulaziz University, 2010-2012
8. Mohamed Abdo Asiri: The diagnostic value of B-type natriuretic peptide for detection
of cardiovascular diseases in peroteneial dialysis patients. Biochemistry
Department, Faculty of Science, King Abdulaziz University, 2010-2013
9. Arwa Al-Zeheri: The impact of different biological modifiers on the stimulation of
monocyte derived dendritic cells toward breast cancer cell line. Department of
Biological Sciences, Faculty of Science, King Abdulaziz University, 2011-2014
10. Amany Al-Zahrani: Studying The Capacity of Boswellia sacra Essential Oil in
Directing Dendritic Cells Differentiation, Maturation, and Immunological
Mohamed Farouk Elshal, Ph.D.
03
Functions. Department of Biological Sciences, Faculty of Science, King
Abdulaziz University, 2012-2015.
11. Mashael Fahad Al-Otaibi: "Association of Vitamin.D with Cardiometabolic Risk
Factors in Rheumatoid Arthritis & Systemic Lupus Erythematosus Patients"
Biochemistry Department, Faculty of Science, King Abdulaziz University, May
2016.
12. Rawan Abdulwahed: " Modulation of CD28 and p38 expression by treatment with
vitamin D in patients with rheumatoid arthritis". Biochemistry Department,
Faculty of Science, King Abdulaziz University, May 2016.
(15) EDITORIAL BOARD MEAMBERSHIP AND REVIWEING COMMITEES:
1. Editor for Journal of Medical Laboratory and Diagnosis
2. Reviewer for Journal of Human and Experimental Toxicology
3. Reviewer for Clinical Immunology Journal
4. Reviewer for Archives of Medical Sciences
5. Reviewer for Journal of Pediatric Biochemistry
6. Reviewer for Journal of Reproductive Sciences
7. Reviewer for Journal of Human Reproductive Sciences
8. Reviewer for Journal of Systems Biology in Reproductive Medicine
9. Reviewer for Journal of Biomarker Insights
10. Reviewer for Journal of Medical Laboratory and Diagnosis
11. Reviewer for Journal of King Saud University (Science)
12. Reviewer for Journal of King Abdulaziz University (Science)
13. Reviewer for King Abdulaziz City for Sciences and Technology, KSA
14. Reviewer for the Deanship of Scientific Research, Taif University, KSA
(16) RESEARCH EXPERIENCE
A. IN THE FIELD OF FLOW CYTOMETRY
DNA Ploidy status and Cell cycle analysis
Intracellular protein analysis
Cellular proliferation assays
Immunophenotyping
Multiparametric analysis
Rare cells isolation and characterization
Sperm chromatin structure assay “SCSA”
Oncogenes analysis (p53, BAX, Bcl-2, p21)
Functional assays (proliferation, oxidative stress, apoptosis)
Experience running different types of flow cytometers and cell sorter:
BD FACScalibur, BD FACSAria, and FACScanto flow cytometers,
Mohamed Farouk Elshal, Ph.D.
04
Bekman-Coulter Cyan flow cytometer
Bekman-Coulter Navious flow cytometer.
Amnis flowsight image cytometer
B. IN THE FIELD OF STEM CELLS
Separation and Maintenance using Magnetic beads separation and Flow
cytometry cell sorter.
Identifying new therapeutics targeting cancer stem cells in vitro using Tissue
culture techniques and flow cytometry
Monitoring response to treatment.
C. IN THE FIELD OF IMMUNOLOGY
Immunophenotyping assays,
Proliferation assays,
magnetic bead separation and sorting assays,
Enzyme Linked Immunosorbent Assay.
MULTIPLEX BEAD-ARRAY ASSAYS (using Luminex bead array
technology)
Hormones analysis,
Cytokines analysis,
Genes analysis,
Soluble proteins analysis.
D. IN-VIVO TECHNIQUES
Tumor induction in experimental animals and methods of treatment thereof.
Induction of Angiogenesis and methods of treatment.
Induction of diabetes type 1 and type 2 in experimental animals and test
antidiabetic drugs.
Induction of hepatic fibrosis in animal models using chemical and test new
materials to treat these abnormalities.
Induction of Cardiac diseases and test compounds that has possible therapeutic
effects.
(17) TEACHING EXPERIENCE:
A. Basic Biochemistry courses
Biochemistry of Metabolism II BIOC 312
Biochemistry of Bioenergetics BIOC 331
Biochemistry of Proteins
Biochemistry of Carbohydrates
Biochemistry of Lipids
Biochemistry of Vitamins
B. Advanced Biochemistry courses (Post graduate)
Medical Biochemistry
Metabolism and its regulation
Biochemistry of oncogenes
C. Immunology courses
Basic Immunology
Mohamed Farouk Elshal, Ph.D.
05
Immunological techniques
Biochemistry of the immune system BIOC 446
D. Flow Cytometry course (Post graduate)
Basics in Cytometry
Nucleic Acid Analysis
Immunophenotyping Assays
Functional Assays
Leukemia and Lymphoma
E. Cancer Molecular Biology course (Post graduate)
Basics in cancer Biology
Oncogenes
Molecular Biochemistry
F. Career Skills and Scientific Writing
(18) COMPUTER SKILLS
o Flow cytometry Complex data analysis using FCS-Express V3.0,
o Flow-Jo multi-analysis of flow cytometric data
o Cell cycle analysis using MOD-FIT,
o Immunophenotyping analysis using different flow cytometry softwares.
o Multiplex Bead Array Assay Analysis software on Luminex xMAP Bead Array
Platform.
o Statistical softwares: SPSS, MedCalc, and Instat.
o MS-DOS, Microsoft windows and Office applications: Microsoft office.
(19) MEMBERSHIPS
The Egyptian Society of Biochemistry and Molecular Biology.
The Egyptian Society of Genetics.
International Clinical Cytometry Society