E16.5 HNF-6 KO; n=1RBP+/-, HNF-6-/-; Alb:Cre

HilarN=1Some questionable areas of possible cystic changes, but question if tissue and fix/sectioningWould like to see in another animal

PeripherySee above, questionable cystic areasSome similar areas seen in control, so likely tissue thing

Sorry about quality of images on this one, went back but couldn’t find better

E16.5 DKO CK19n=1

Hilar- Little to no ductal plate

Interlobular/Hilar

Peripheral – hard to find good ductal platesMore background peripherally, don’t think these are disorganized CK cells, but perhaps? N=1If not, what pathway/s is/are upregulated to get those P60 and P30 cells!!!! (if not prolif)