ÖZGEÇMİŞ

PROF.DR. ÖMER AKYOL

1. KİŞİSEL BİLGİLER -Doğum Yeri ve Yılı: SUŞEHRİ, 1967 -Haberleşme adresi, telefon no, faks no, e-mail Dr. Ömer Akyol Hacettepe Üniversitesi Tıp Fakültesi Biyokimya Anabilim Dalı Öğr. Üyesi Dekanlık Binası 06100 Sıhhıye/ANKARA E-mail: oakyol@hacettepe.edu.tr İş tel: 0312-3051652/116 İş faks: 0312-3100580 2. EĞİTİM a) Lisans: ONDOKUZ MAYIS ÜNİVERSİTESİ TIP FAKÜLTESİ, 1989 b) Tıpta uzmanlık: ANKARA ÜNİVERSİTESİ TIP FAKÜLTESİ BİYOKİMYA ANABİLİM DALI, 1994 c) Doktora: FIRAT ÜNİVERSİTESİ TIP FAKÜLTESİ TIBBİ BİYOLOJİ VE GENETİK ANABİLİM DALI, 2003 d) Akademik Ünvanları (Alındıkları üniversiteler ve tarihleri) - Yrd. Doç.: İNÖNÜ ÜNİVERSİTESİ, 1996 - Doçent: İNÖNÜ ÜNİVERSİTESİ, 1996 - Profesör: HACETTEPE ÜNİVERSİTESİ, 2002 3. AKADEMİK DENEYİM Anabilim Dalı Başkanlığı (vekil) İnönü Üniversitesi 1999-1999 Yönetim Kurulu Üyeliği İnönü Ü. Sağlık Bil. Ens. 1998-2001 Etik Kurul Üyeliği İnönü Ü. Tıp Fak. 1996-2001 Dönem I Koord. Yrd. İnönü Ü. Tıp Fak. 1997-1997 Dönem II Koord. İnönü Ü. Tıp Fak. 1998-1998 Dönem III Koord. İnönü Ü. Tıp Fak. 1999-1999 Tabip Odası Yn. Kur.Üyeliği Malatya Tabip Odası 1998-2000 Tabip Odası Onur Kur.Üyeliği Malatya Tabip Odası 2000-2002 4. MESLEKİ DENEYİM Şubat 1990-Kasım 1990 Tunceli Devlet Hast. Acil Plk., Pratisyen Hekim Aralık 1990-Temmuz 1994 Ankara Ü. Tıp Fak. Biyokimya A.D., Araş. Görevlisi Ekim 1994-Ocak 1995 Niğde Devlet Hast. Uzman Hekim Ekim 1995-Ekim 1996 İnönü Ü. Tıp Fak. Biyokimya A.D., Yrd.Doç. Ekim 1996-Nisan 2002 İnönü Ü. Tıp Fak. Biyokimya A.D., Doçent Nisan 2002- Hacettepe Ü. Tıp Fak. Biyokimya A.D., Profesör

5. ÇALIŞMA ALANLARI

- Reperfüzyon hasarları ve kanser başta olmak üzere değişik hastalıklarda oksidan/antioksidan sistemlerin araştırılması - Kafeik asit fenetil ester (CAPE)’in antioksidan etkileri - İz elementler ve çeşitli hastalıklardaki düzeyleri (serum, idrar, saç, tırnak)

- Spinal kord hasarlarında dokudaki biyokimyasal değişikliklerin araştırılması - Mn-SOD polimorfizminin araştırılması

6. YAPILAN TEZLER

Uzmanlık tezi: Beyin tumorlerinde doku superoksit dismutaz, katalaz ve glutatyon peroksidaz aktiviteleri. Ankara Universitesi, 1994, Tez Danışmanı: Doç.Dr. Ilker Durak. Doktora tezi: Şizofreni hastalarında mangan süperoksit dismutaz (Mn-SOD) gen polimorfizminin araştırılması. Fırat Üniversitesi, 2003, Tez Danışmanı: Prof.Dr. Halit Elyas

7. YAPTIRILAN TEZLER

• Romatoid artritli hastaların eritrosit ve plazmalarında süperoksit dismutaz ve katalaz aktiviteleri (Yüksek lisans tezi-1997).

• Gastrik kanser, ülser ve atrofik gastriti olan hastaların mide sularında malondialdehit, süperoksit dismutaz, katalaz ve glutatyon peroksidaz aktiviteleri (Doktora tezi-1999).

• Çeşitli göğüs hastalıklarında bronşial lavaj sıvısı ve plazmada ksantin oksidaz ve adenozin deaminaz aktiviteleri ile nitrik oksit ve malondialdehit seviyeleri (Yüksek lisans tezi-2000).

• Deneysel karaciğer iskemi-reperfüzyonu oluşturulan sıçanlarda doku oksidan-antioksidanlarının durumu: doku hasarına E vitamini ve kafeik asit fenetil esterin (CAPE) etkileri (Doktora tezi-2001).

8. PROJELER a) “Pankreas adacık hücre izolasyonu projesi”. “Devlet Planlama Teskilati” 2008. Proje # 2008K120370. b) Baş-boyun kanserlerinde kemoterapötik ajan olarak kullanılan cisplatinin ototoksik etkisinin plazma oksidan/antioksidan sistemler açısından değerlendirilmesi, İÜBAP Projesi, 2002/05, Proje Yöneticisi, 2002. c) Şizofrenide Manganez süperoksit dismutaz (Mn-SOD) enziminin gen polimorfizminin araştırılması: hastalık alt grupları, semptomlar ve prognoz ile polimorfizm arasındaki ilişkiler, FÜBAP Projesi, 2002/6267, Proje Yürütücüsü, 2002. d) Ratlarda karaciğer iskemi reperfüzyon injurisinde doku ve plazma antioksidan sistemlerinin durumu, İ.Ü. Araştırma Fonu, 2000/31, Proje Yöneticisi, 2000. e) Gastrit, kanser, ülser hastalarında mide suları malondialdehit düzeyleri ve antioksidan enzim aktiviteleri, İ.Ü. Araştırma Fonu, 1998/32, Proje Yöneticisi, 1998. 9. YURTDIŞI DENEYİMİ

a) Ağustos 2009-Ekim 2010 (14 months with Professor Malcolm K. Brenner) “Redirected T cells for chronic lymphocytic leukemia” Baylor College of Medicine, Center for Cell and Gene Therapy, Houston, Texas, USA [TÜBİTAK Doktora sonrası yurtdışı burs programı, BİDEB tarafından desteklenmiştir] b) Eylül 2008-Austos 2009 (11 months with Professor Mark Kindy) “The investigation of protective effect of caffeic acid phenethylester on traumatic spinal cord injury”. The collaboration of Department of Radiology and Basic Radiology and Department of Neurological Sciences. Medical University of South Carolina, Charleston, SC, USA. c) Haziran 1998-Eylül 1998 (4 months, with Professor Krystyna Frenkel): “The effects of 17β-estradiol and Dimethylbenz(a)anthracene (DMBA) on antioxidant enzymes in MCF-7 and MCF-10A cell culture”. Nelson Institute of Environmental Medicine, PHL 802, Laboratory of Oxidative Mechanisms in Carcinogenesis, New York Medical Center, New York, NY, USA [TUBITAK NATO-B2 burs programınca desteklenmiştir]. d) Ocak 1997-Nisan 1997 (4 months, with Professor Sidney Mirvish): “Changes in liver lipid peroxidation and antioxidants in rats subjected to diethylnitrosamine”.The University of Nebraska Medical Center, Eppley Cancer Institute, Omaha, Nebraska, USA

10. ÜYELİKLER Türk Biyokimya Derneği Türk Klinik Biyokimya Derneği Ankara Tabip Odası The Turkish American Scientists and Scholars Association (TASSA) 11. ÖDÜLLER • TÜBİTAK 2006 Yılı Teşvik Ödülü (Sağlık Bilimleri) • Duygudurum Bozuklukları Araştırma Ödülü Dalında İkincilik Ödülü. [41. Ulusal Psikiyatri Kongresi

15-20 Kasım 2005, Erzurum. H.A.Savaş, H.S.Gergerlioğlu, F.Armutçu, H.Herken, H.R. Yılmaz, E.Koçoğlu, S.Selek, H.Tutkun, S.S.Zoroğlu, Ö.Akyol. Nitric oxide, adenosine deaminase, xanthine oxidase and superoxide dismutase in patients with panic disorder: alterations by antidepressant treatment.]

• Toraks Derneği Yurtdışı Yayın Birincilik ödülü [Toraks Derneği 8. Yıllık Kongresi 2005. Z. Yıldırım, Y. Türköz, M. Kotuk, F. Armutçu, A. Gürel, M. Iraz, S. Özen, İ. Aydoğdu, Ö. Akyol. Effects of aminoguanidine and antioxidant erdosteine on bleomycine-induced lung fibrosis in rats]

• En İyi Sözel Bildiri Ödülü [2nci Ulusal Serebrovasküler hastalıklar kongresi 2004, A. İlhan, F. Armutçu, A. Gürel, Ö. Akyol. Tavşan spinal kord iskemi/reperfüzyon modelinde nebivololun prognoz ve oksidatif hasar üzerine etkileri]

• Araştırma İkincilik Ödülü [Türkiye Psikiyatri Derneği Bahar Sempozyumları 2002, H.A. Savaş, H. Herken, M. Yürekli, E. Uz, H. Tutkun, S.S. Zoroğlu, M.E. Özen, M. Cengiz, Ö. Akyol. Nitrik oksit ve adrenomedullinin iki uçlu duygudurum bozukluğundaki olası rolü]

• Araştırma Birincilik Ödülü [Türkiye Psikiyatri Derneği Bahar Sempozyumları 2002, S.S. Zoroğlu, H. Herken, M. Yürekli, E. Uz, H. Tutkun, H.A. Savaş, C. Bağcı, M.E. Özen, B. Cengiz, E.A. Çakmak, M.I. Doğru, Ö. Akyol. Şizofreni hastalarında adrenomedullin ve nitik oksit düzeyleri ve hastalığın kliniği ile ilişkisi]

• Poster Başarı Ödülü [XVI. Ulusal Biyokimya Kongresi İkinci Uluslar arası Biyobilim Günleri 2000, Ö.Akyol, H.Özyurt, S.Söğüt, M.K. Irmak. Böbrek iskemi reperfüzyon oluşturulmuş ratların serumundaki oksidatif stres parametrelerine kafeik asit fenetil esterin etkisi]

12. YABANCI DİLLER

İngilizce (konuşma, yazma) ve Almanca (okuma ve anlama)

13. HAKEMLİK YAPTIĞI ULUSLAR ARASI VE ULUSAL DERGİLER

1. DNA and Cell Biology 2. Biological Psychiatry 3. Journal of Neural Transmission 4. Molecular and Cellular Biochemistry 5. Age and Ageing 6. Neurochemistry International 7. Acta Neuropsychiatrica 8. Renal Failure 9. The American Journal of Psychiatry 10. Clinica Chimica Acta 11. Life Sciences 12. Macromolecular Bioscience 13. Journal of Cellular Biochemistry 14. The European Journal of General Medicine 15. Pepticide Biochemistry and Physiology 16. Nutrition Research 17. The Journal The National Medical Association 18. Journal of Psychiatry and Neuroscience 19. Tohoku Journal of Experimental Medicine 20. Progress in Neuropsychopharmacology and Biological Psychiatry (in Editorial Board) 21. Mediators of Inflammation 22. Türk Hematoloji-Onkoloji Dergisi (Danışma Kurulu Üyesi)

23. Fırat Üniversitesi Sağlık Bilimleri Dergisi (Fırat University Journal of Health Sciences) (Danışma Kurulu Üyesi)

24. İnönü Üniversitesi Tıp Fakültesi Dergisi (Danışma Kurulu Üyesi) 25. Türkiye Klinikleri Tıp Dergisi (Danışma Kurulu Üyesi) 26. Gaziosmanpaşa Üniversitesi Tıp Fakültesi Dergisi (Danışma Kurulu Üyesi) 27. Spatula DD

14. DİĞER GÖREV VE FAALİYETLER a) Kurs katılımı (Mayıs 2008): Vienna School of Clinical Research, “Introduction to Good Clinical Practice- Basics of GCP implementation in clinical trials”, Ankara, TURKEY b) Konferans katılımı (Nisan 2008): TASSA 2008 Annual Conference “Innovation as driver for social transformation and economic growth” Harward University in Boston, MA, USA c) Konferans katılımı: 2009 Center for Cell and Gene Therapy Conference. The San Luis Resort and Conference Center, Galveston, TX, November 19-20, 2009. d) 6th Annual Texas Children’s Cancer Center & Hematology Service Research Symposium. Trevisio John P. McGovern Texas Medical Center Commons, Houston, Texas, USA, March 12, 2010. 15. YAYINLAR Ektedir. 16. ATIFLAR Kaynak Web of Science olmak üzere Nisan 2011 itibariyle atıf sayısı 2277, h-index: 28. 17. ULUSLARARASI YAYINLAR 115 adet SCI ve SCI-Expanded kapsamında yayını vardır (Ektedir) 18. ULUSAL YAYINLAR 31 adet hakemli ulusal dergilerde yayını vardır (Ektedir) 19. BİLDİRİ VE DAVETLİ KONUŞMALAR a) Uluslararası bildiriler: 43 adet uluslararası bildirisi vardır (Ektedir) b) Davetli Konuşmalar: 1) 2007 October: “Metabolic parameters of the no pathway in relationship to psychiatric disorders” European College of Neuropsychopharmacology, 20th ECNP Congress, Vienna, AUSTRIA 2) 2006 September: “Nonsynaptic Transmission in Central Nervous System and Nitric Oxide”. The Congress of Ion Channels and Oxidative Stress, Isparta, TURKEY 3) 2005 June: “Oxidative damage, antioxidant enzymes and lipid peroxidation in autism: are there any genetic predisposition regarding these processes.” Oxidative Stress in Autism Symposium, NYS Institute fo Basic Research in Developmental Disabilities, Staten Island, NY, USA 4) 2002 May: “Increased lipid peroxidation in schizophrenia; a marker of membrane breakdown?” 11th Association of Eurepean Psychiatrists Congress, Stockholm, SWEDEN.

ULUSLARARASI SCI VE SCI-EXPANDED KAPSAMINDAKİ YAYINLARI 1. PINAR T, ATLI AK, ALACAM H, KARABULUT I, SOGUKSULU I, ATAS A, OMAR MB, AMIN NA, AKYOL O. THE EFFECTS OF NOISE ON OXIDATIVE AND ANTIOXIDATIVE BALANCA IN HUMAN ERYTHROCYTES. INT J HEMATOL ONCOL 2011; 21(1):10-18. 2. OZYURT B, SONGUR A, SARSILMAZ M, AKYOL O, NAMLI M, DEMIREL R. DERMATOGLYPICS AS MARKERS OF PRENATAL DISTURBANCES IN SCHIZOPHRENIA: A CASE-CONTROL STUDY. TURK J MED SCI 2010; 40(6):917-24. 3. ULGER Z, ARIOGUL S, CANKURTARAN M, HALIL M, YAVUZ BB, ORHAN B, KAVAS GO, ARIBAL P, CANLAR S, DEDE DS, OZKAYLAR N, AKYOL O. INTRA-ERYTHROCYTE MAGNESIUM LEVELS AND THEIR CLINICAL IMPLICATIONS IN GERIATRIC OUTPATIENTS. J NUTR HEALTH AGING 2010; 14(10):810-14. 4. OZEROL E, BILGIC S, IRAZ M, CIGLI A, ILHAN, AKYOL. THE PROTECTIVE EFFECT OF ERDOSTEINE ON SHORT-TERM GLOBAL BRAIN ISCHEMIA/REPERFUSION INJURY IN RATS. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2009; 33: 20-24.

5. ULGER Z, ARIOGUL S, ORHAN B, KAVAS GO, ARIBAL P, AKYOL O. A COMPARATIVE STUDY ON COPPER AND ZINC CONCENTRATIONS IN GERIATRIC INDIVIDUALS. TRACE ELEM ELECTROLYTES 2008; 25:75-78. 6. OZTURK E, DEMIRBILEK S, KOROGLU A, BUT A, BEGEC ZO, GULEC M, AKYOL O, ERSOY MO. PROPOFOL AND ERYTHROPOIETIN ANTIOXIDANT PROPERTIES IN RAT BRAIN INJURED TISSUE. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2008; 32:81-86. 7. KIZILAY A, KALCIOGLU MT, OZUGURLU F, OZYURT H, ALADAG I, OZTURAN O, AKYOL O. SERUM NITRIC OXIDE LEVELS IN PATIENTS WITH HEAD AND NECK SQUAMOUS CELL CARCINOMA. KULAK BURUN BOGAZ IHTIS DERG 2007; 17:148-151. 8. AKYOL O, ALACAM H. METABOLIC PARAMETERS OF THE NO PATHWAY IN RELATIONSHIP TO PSYCHIATRIC DISORDERS. EUR NEUROPSYCHOPHARMACOL 2007; 17 (SUPPL 4): S190-S190. 9. YUCE H, HEPSEN IF, TEKEDERELI I, KESKIN U, ELYAS H, AKYOL O. LACK OF ASSOCIATION BETWEEN PSEUDOEXFOLIATION SYNDROME AND MANGANESE SUPEROXIDE DISMUTASE POLYMORPHISM. CURR EYE RES 2007; 32(4):387-91. 10. YILMAZ N, HERKEN H, CICEK HK, CELIK A, YUREKLI M, AKYOL O. INCREASED LEVELS OF NITRIC OXIDE, CORTISOL AND ADRENOMEDULLIN IN PATIENTS WITH CHRONIC SCHIZOPHRENIA. MED PRINC PRACT 2007; 16(2):137-41. 11. HERKEN H, GUREL A, SELEK S, ARMUTCU F, OZEN ME, BULUT M, KAP O, YUMRU M, SAVAS HA, AKYOL O. ADENOSINE DEAMINASE, NITRIC OXIDE, SUPEROXIDE DISMUTASE, AND XANTHINE OXIDASE IN PATIENTS WITH MAJOR DEPRESSION: IMPACT OF ANTIDEPRESSANT TREATMENT. ARCH MED RES 2007; 38(2):247-52. 12. OZYURT B, SARSILMAZ M, AKPOLAT N, OZYURT H, AKYOL O, HERKEN H, KUS I. THE PROTECTIVE EFFECTS OF OMEGA-3 FATTY ACIDS AGAINST MK-801-INDUCED NEUROTOXICITY IN PREFRONTAL CORTEX OF RAT. NEUROCHEM INT 2007; 50(1):196-202. 13. AKYOL O. RE: ASSOCIATIONS BETWEEN MN-SOD GENETIC POLYMORPHISM AND SCHIZOPHRENIA. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2006; 30:761. 14. GULEC M, SONGUR A, SAHIN S, OZEN OA, SARSILMAZ M, AKYOL O. ANTIOXIDANT ENZYME ACTIVITIES AND LIPID PEROXIDATION PRODUCTS IN HEART TISSUE OF SUBACUTE AND SUBCHRONIC FORMALDEHYDE-EXPOSED RATS: A PRELIMINARY STUDY. TOXICOL IND HEALTH 2006; 22(3):117-24. 15. INCE H, KANDEMIR E, BAGCI C, GULEC M, AKYOL O. THE EFFECT OF CAFFEIC ACID PHENETHYL ESTER ON SHORT-TERM ACUTE MYOCARDIAL ISCHEMIA. MED SCI MONIT 2006; 12(5):BR187-93. 16. IRAZ M, OZEROL E, GULEC M, TASDEMIR S, IDIZ N, FADILLIOGLU E, NAZIROGLU M, AKYOL O. PROTECTIVE EFFECT OF CAFFEIC ACID PHENETHYL ESTER (CAPE) ADMINISTRATION ON CISPLATIN-INDUCED OXIDATIVE DAMAGE TO LIVER IN RAT. CELL BIOCHEM FUNCT 2006; 24(4):357-61. 17. SAVAS HA, GERGERLIOGLU HS, ARMUTCU F, HERKEN H, YILMAZ HR, KOCOGLU E, SELEK S, TUTKUN H, ZOROGLU SS, AKYOL O. ELEVATED SERUM NITRIC OXIDE AND SUPEROXIDE DISMUTASE IN EUTHYMIC BIPOLAR PATIENTS: IMPACT OF PAST EPISODES. WORLD J BIOL PSYCHIATRY 2006; 7(1):51-5.

18. HERKEN H, AKYOL O, YILMAZ HR, TUTKUN H, SAVAS HA, OZEN ME, KALENDEROGLU A, GULEC M. NITRIC OXIDE, ADENOSINE DEAMINASE, XANTHINE OXIDASE AND SUPEROXIDE DISMUTASE IN PATIENTS WITH PANIC DISORDER: ALTERATIONS BY ANTIDEPRESSANT TREATMENT. HUM PSYCHOPHARMACOL 2006; 21(1):53-9. 19. OZGOCMEN S, OZYURT H, SOGUT S, AKYOL O. CURRENT CONCEPTS IN THE PATHOPHYSIOLOGY OF FIBROMYALGIA: THE POTENTIAL ROLE OF OXIDATIVE STRESS AND NITRIC OXIDE. RHEUMATOL INT 2006; 26(7):585-97. 20. OZGOCMEN S, OZYURT H, SOGUT S, AKYOL O, ARDICOGLU O, YILDIZHAN H. ANTIOXIDANT STATUS, LIPID PEROXIDATION AND NITRIC OXIDE IN FIBROMYALGIA: ETIOLOGIC AND THERAPEUTIC CONCERNS. RHEUMATOL INT 2006; 26(7):598-603. 21. VıRıT O, HERKEN H, NACAK M, AKYOL O, TUTKUN E, SAVAS HA, YANıK M, NAMLı M. SCHıZOPHRENıA AND ANGıOTENSıN CONVERTıNG ENZYME GENE ASSOCıATıON ıN TURKıSH PATıENTS. NEUROL PSYCHIATRY BRAIN RES 2005; 12: 153-158. 22. CAGLI K, BAGCI C, GULEC M, CENGIZ B, AKYOL O, SARI I, CAVDAR S, PENCE S, DINCKAN H. IN VIVO EFFECTS OF CAFFEIC ACID PHENETHYL ESTER ON MYOCARDIAL ISCHEMIA-REPERFUSION INJURY AND APOPTOTIC CHANGES IN RATS. ANN CLIN LAB SCI 2005; 35(4):440-8. 23. OZUGURLU F, SAHIN S, IDIZ N, AKYOL O, ILHAN A, YIGITOGLU R, ISIK B. THE EFFECT OF NIGELLA SATIVA OIL AGAINST EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS VIA NITRIC OXIDE AND OTHER OXIDATIVE STRESS PARAMETERS. CELL MOL BIOL 2005; 51(3):337-42. 24. INANC F, KILINC M, KIRAN G, GUVEN A, KURUTAS EB, CIKIM IG, AKYOL O. RELATIONSHIP BETWEEN OXIDATIVE STRESS IN CORD BLOOD AND ROUTE OF DELIVERY. FETAL DIAGN THER 2005; 20(5):450-3. 25. OZTURK E, DEMIRBILEK S, KADIR BUT A, SARICICEK V, GULEC M, AKYOL O, OZCAN ERSOY M. ANTIOXIDANT PROPERTIES OF PROPOFOL AND ERYTHROPOIETIN AFTER CLOSED HEAD INJURY IN RATS. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2005; 29(6):922-7. 26. KALCIOGLU MT, KIZILAY A, GULEC M, KARATAS E, IRAZ M, AKYOL O, EGRI M, OZTURAN O. THE PROTECTIVE EFFECT OF ERDOSTEINE AGAINST OTOTOXICITY INDUCED BY CISPLATIN IN RATS. EUR ARCH OTORHINOLARYNGOL 2005; 262(10):856-63. 27. GERGERLIOGLU HS, SAVAS HA, ARMUTCU F, HERKEN H, ZOROGLU SS, TUTKUN H, YILMAZ HR, SELEK S, AKYOL O. INCREASED NITRIC OXIDE AND SUPEROXIDE DISMUTASE LEVELS IN EUTHYMIC BIPOLAR PATIENTS: IMPACT OF PAST EPISODES. FASEB J 2005; 19 (SUPPL): 701. 28. KUKU I, AYDOGDU I, BAYRAKTAR N, KAYA E, AKYOL O, ERKURT MA. OXIDANT/ANTIOXIDANT PARAMETERS AND THEIR RELATIONSHIP WITH MEDICAL TREATMENT IN MULTIPLE MYELOMA. CELL BIOCHEM FUNCT 2005; 23(1):47-50. 29. AKYOL O, YANIK M, ELYAS H, NAMLI M, CANATAN H, AKIN H, YUCE H, YILMAZ HR, TUTKUN H, SOGUT S, HERKEN H, OZYURT H, SAVAS HA, ZOROGLU SS. ASSOCIATION BETWEEN ALA-9VAL POLYMORPHISM OF MN-SOD GENE AND SCHIZOPHRENIA. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2005; 29(1):123-31. 30. ILHAN A, IRAZ M, GUREL A, ARMUTCU F, AKYOL O. CAFFEIC ACID PHENETHYL ESTER EXERTS A NEUROPROTECTIVE EFFECT ON CNS AGAINST PENTYLENETETRAZOL-INDUCED SEIZURES IN MICE. NEUROCHEM RES 2004; 29(12):2287-92. 31. ARMUTCU F, OZEROL E, GUREL A, KANTER M, VURAL H, YAKINCI C, AKYOL O. EFFECT OF LONG-TERM THERAPY WITH SODIUM VALPROATE ON NAIL AND SERUM TRACE ELEMENT STATUS IN EPILEPTIC CHILDREN. BIOL TRACE ELEM RES 2004; 102(1-3):1-10. 32. ILHAN A, AKYOL O, ARMUTCU F, IRAZ M, GUREL A. INVESTIGATION OF OXIDANT/ANTIOXIDANT PARAMETERS IN PENTHYLENETETRAZOL-INDUCED SEIZURES IN MICE AND THE PROTECTIVE EFFECT OF ERDOSTEINE TREATMENT. J NEUROL 2004; 251 (SUPPL): 93-95. 33. ILHAN A, YILMAZ HR, ARMUTCU F, GUREL A, AKYOL O. THE PROTECTIVE EFFECT OF NEBIVOLOL ON ISCHEMIA/REPERFUSION INJURY IN RABBIT SPINAL CORD. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2004; 28(7):1153-60.

34. KALCIOGLU MT, KIZILAY A, YILMAZ HR, UZ E, GULEC M, OZTURAN O, AKYOL O. ADENOSINE DEAMINASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, GLUTATHIONE PEROXIDASE ACTIVITIES AND MALONDIALDEHYDE LEVELS IN THE SERA OF PATIENTS WITH HEAD AND NECK CARCINOMA. KULAK BURUN BOGAZ IHTIS DERG 2004;12(1-2):16-22. 35. GUREL A, TOMAC N, YILMAZ HR, TEKEDERELI I, AKYOL O, ARMUTCU F, YUCE H, AKIN H, OZCELIK N, ELYAS H. THE ALA-9VAL POLYMORPHISM IN THE MITOCHONDRIAL TARGETING SEQUENCE (MTS) OF THE MANGANESE SUPEROXIDE DISMUTASE GENE IS NOT ASSOCIATED WITH JUVENILE-ONSET ASTHMA. CLIN BIOCHEM. 2004; 37(12):1117-20. 36. YILDIRIM Z, TURKOZ Y, KOTUK M, ARMUTCU F, GUREL A, IRAZ M, OZEN S, AYDOGDU I, AKYOL O. EFFECTS OF AMINOGUANIDINE AND ANTIOXIDANT ERDOSTEINE ON BLEOMYCIN-INDUCED LUNG FIBROSIS IN RATS. NITRIC OXIDE 2004; 11(2):156-65. 37. EGE E, ILHAN A, GUREL A, AKYOL O, OZEN S. ERDOSTEINE AMELIORATES NEUROLOGICAL OUTCOME AND OXIDATIVE STRESS DUE TO ISCHEMIA/REPERFUSION INJURY IN RABBIT SPINAL CORD. EUR J VASC ENDOVASC SURG 2004; 28(4):379-86. 38. AKYOL O, ZOROGLU SS, ARMUTCU F, SAHIN S, GUREL A. NITRIC OXIDE AS A PHYSIOPATHOLOGICAL FACTOR IN NEUROPSYCHIATRIC DISORDERS. IN VIVO 2004; 18(3):377-90. 39. KIZILAY A, KALCIOGLU MT, OZEROL E, IRAZ M, GULEC M, AKYOL O, OZTURAN O. CAFFEIC ACID PHENETHYL ESTER AMELIORATED OTOTOXICITY INDUCED BY CISPLATIN IN RATS. J CHEMOTHER 2004; 16(4):381-7. 40. KIZILAY A, KALCIOGLU T, OZYURT H, VURAL H, SOGUT S, COKKESER Y, AKYOL O. CONCENTRATION OF TRACE ELEMENTS IN LARYNX AND SKIN TISSUES WITH EPIDERMOID CANCER. TRACE ELEM ELECTROL 2004; 21:17-121. 41. ERDOGAN H, FADILLIOGLU E, OZGOCMEN S, SOGUT S, OZYURT B, AKYOL O, ARDICOGLU O. EFFECT OF FISH OIL SUPPLEMENTATION ON PLASMA OXIDANT/ANTIOXIDANT STATUS IN RATS. PROSTAGLANDINS LEUKOT ESSENT FATTY ACIDS 2004; 71(3):149-52. 42. YILMAZ HR, IRAZ M, SOGUT S, OZYURT H, YILDIRIM Z, AKYOL O, GERGERLIOGLU S. THE EFFECTS OF ERDOSTEINE ON THE ACTIVITIES OF SOME METABOLIC ENZYMES DURING CISPLATIN-INDUCED NEPHROTOXICITY IN RATS. PHARMACOL RES 2004; 50(3):287-90. 43. ILHAN A, AKYOL O, GUREL A, ARMUTCU F, IRAZ M, OZTAS E. PROTECTIVE EFFECTS OF CAFFEIC ACID PHENETHYL ESTER AGAINST EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS-INDUCED OXIDATIVE STRESS IN RATS. FREE RADIC BIOL MED 2004; 37(3):386-94. 44. SOGUT S, OZYURT H, ARMUTCU F, KART L, IRAZ M, AKYOL O, OZEN S, KAPLAN S, TEMEL I, YILDIRIM Z. ERDOSTEINE PREVENTS BLEOMYCIN-INDUCED PULMONARY FIBROSIS IN RATS. EUR J PHARMACOL 2004; 494(2-3):213-20. 45. AKYOL O, CANATAN H, YILMAZ HR, YUCE H, OZYURT H, SOGUT S, GULEC M, ELYAS H. PCR/RFLP-BASED COST-EFFECTIVE IDENTIFICATION OF SOD2 SIGNAL (LEADER) SEQUENCE POLYMORPHISM (ALA-9VAL) USING NGOM IV: A DETAILED METHODOLOGICAL APPROACH. CLIN CHIM ACTA 2004; 345(1-2):151-9. 46. AYDIN E, SOGUT S, OZYURT H, OZUGURLU F, AKYOL O. COMPARISON OF SERUM NITRIC OXIDE, MALONDIALDEHYDE LEVELS, AND ANTIOXIDANT ENZYME ACTIVITIES IN BEHCET'S DISEASE WITH AND WITHOUT OCULAR DISEASE. OPHTHALMIC RES 2004; 36(3):177-82. 47. OZCAN ME, GULEC M, OZEROL E, POLAT R, AKYOL O. ANTIOXIDANT ENZYME ACTIVITIES AND OXIDATIVE STRESS IN AFFECTIVE DISORDERS. INT CLIN PSYCHOPHARMACOL 2004; 19(2):89-95. 48. YANIK M, VURAL H, TUTKUN H, ZOROGLU SS, SAVAS HA, HERKEN H, KOCYIGIT A, KELES H, AKYOL O. THE ROLE OF THE ARGININE-NITRIC OXIDE PATHWAY IN THE PATHOGENESIS OF BIPOLAR AFFECTIVE DISORDER. EUR ARCH PSYCHIATRY CLIN NEUROSCI 2004; 254(1):43-7. 49. OZEROL E, OZEROL I, GOKDENIZ R, TEMEL I, AKYOL O. EFFECT OF SMOKING ON SERUM CONCENTRATIONS OF TOTAL HOMOCYSTEINE, FOLATE, VITAMIN B12, AND NITRIC OXIDE IN PREGNANCY: A PRELIMINARY STUDY. FETAL DIAGN THER 2004; 19(2):145-8.

50. OZEN S, AKYOL O, IRAZ M, SOGUT S, OZUGURLU F, OZYURT H, ODACI E, YILDIRIM Z. ROLE OF CAFFEIC ACID PHENETHYL ESTER, AN ACTIVE COMPONENT OF PROPOLIS, AGAINST CISPLATIN-INDUCED NEPHROTOXICITY IN RATS.J APPL TOXICOL 2004; 24(1):27-35. 51. ILHAN A, GUREL A, ARMUTCU F, KAMISLI S, IRAZ M, AKYOL O, OZEN S. GINKGO BILOBA PREVENTS MOBILE PHONE-INDUCED OXIDATIVE STRESS IN RAT BRAIN. CLIN CHIM ACTA 2004; 340(1-2):153-62. 52. OZYURT H, SOGUT S, YILDIRIM Z, KART L, IRAZ M, ARMUTCU F, TEMEL I, OZEN S, UZUN A, AKYOL O. INHIBITORY EFFECT OF CAFFEIC ACID PHENETHYL ESTER ON BLEOMYCINE-INDUCED LUNG FIBROSIS IN RATS. CLIN CHIM ACTA 2004; 339(1-2):65-75. 53. GUREL A, ARMUTCU F, SAHIN S, SOGUT S, OZYURT H, GULEC M, KUTLU NO, AKYOL O. PROTECTIVE ROLE OF ALPHA-TOCOPHEROL AND CAFFEIC ACID PHENETHYL ESTER ON ISCHEMIA-REPERFUSION INJURY VIA NITRIC OXIDE AND MYELOPEROXIDASE IN RAT KIDNEYS. CLIN CHIM ACTA 2004; 339(1-2):33-41. 54. ILHAN A, OZEROL E, GULEC M, ISIK B, ILHAN N, ILHAN N, AKYOL O. THE COMPARISON OF NAIL AND SERUM TRACE ELEMENTS IN PATIENTS WITH EPILEPSY AND HEALTHY SUBJECTS. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2004; 28(1):99-104. 55. OZGOCMEN S, SOGUT S, ARDICOGLU O, FADILLIOGLU E, PEKKUTUCU I, AKYOL O. SERUM NITRIC OXIDE, CATALASE, SUPEROXIDE DISMUTASE, AND MALONDIALDEHYDE STATUS IN PATIENTS WITH ANKYLOSING SPONDYLITIS. RHEUMATOL INT 2004; 24(2):80-3. 56. OZYURT H, TOTAN A, SAHIN S, KILINC C, SOGUT S, AKYOL O. MATERNAL SERUM AND AMNIOTIC FLUID HYDROXYPROLINE LEVELS IN NEURAL TUBE DEFECTS. FETAL DIAGN THER 2003; 18(5):321-3. 57. SARSILMAZ M, SONGUR A, KUS I, OZYURT B, GULEC M, SOGUT S, ILHAN A, AKYOL O. THE REGULATORY ROLE OF DIETARY Ω-3 ESSENTIAL FATTY ACIDS ON OXIDANT/ANTIOXIDANT BALANCE IN RAT HIPPOCAMPUS. NEUROSCI RES COMMUN 2003; 33:114-123. 58. SARSILMAZ M, SONGUR A, OZYURT H, KUS I, OZEN OA, OZYURT B, SOGUT S, AKYOL O. POTENTIAL ROLE OF DIETARY OMEGA-3 ESSENTIAL FATTY ACIDS ON SOME OXIDANT/ANTIOXIDANT PARAMETERS IN RATS' CORPUS STRIATUM. PROSTAGLANDINS LEUKOT ESSENT FATTY ACIDS 2003; 69(4):253-9. 59. OZEROL E, ULVI H, ILHAN N, GULEC M, ILHAN A, ILHAN N, AKYOL O. DETERMINATION OF COPPER, ZINC AND MANGANESE IN NAIL AND SERUM FROM PATIENTS WITH MIGRAINE. TRACE ELEM ELECTROLY 2003: 20:230-233. 60. UZ E, SAHIN S, HEPSEN IF, VAR A, SOGUT S, AKYOL O. THE RELATIONSHIP BETWEEN SERUM TRACE ELEMENT CHANGES AND VISUAL FUNCTION IN HEAVY SMOKERS. ACTA OPHTHALMOL SCAND 2003; 81(2):161-4. 61. GULEC M, AKIN H, YUCE H H, ERGIN E, ELYAS H, YALCIN O, AKYOL O. ADENOSINE DEAMINASE AND XANTHINE OXIDASE ACTIVITIES IN BLADDER WASHING FLUID FROM PATIENTS WITH BLADDER CANCER: A PRELIMINARY STUDY. CLIN BIOCHEM 2003; 36(3):193-6. 62. YANIK M, VURAL H, KOCYIGIT A, TUTKUN H, ZOROGLU SS, HERKEN H, SAVAS HA, KOYLU A, AKYOL O. IS THE ARGININE-NITRIC OXIDE PATHWAY INVOLVED IN THE PATHOGENESIS OF SCHIZOPHRENIA? NEUROPSYCHOBIOLOGY 2003; 47(2):61-5. 63. SOGUT S, ZOROGLU SS, OZYURT H, YILMAZ HR, OZUGURLU F, SIVASLI E, YETKIN O, YANIK M, TUTKUN H, SAVAS HA, TARAKCIOGLU M, AKYOL O. CHANGES IN NITRIC OXIDE LEVELS AND ANTIOXIDANT ENZYME ACTIVITIES MAY HAVE A ROLE IN THE PATHOPHYSIOLOGICAL MECHANISMS INVOLVED IN AUTISM. CLIN CHIM ACTA 2003; 331(1-2):111-7. 64. ZOROGLU SS, YUREKLI M, MERAM I, SOGUT S, TUTKUN H, YETKIN O, SIVASLI E, SAVAS HA, YANIK M, HERKEN H, AKYOL O. PATHOPHYSIOLOGICAL ROLE OF NITRIC OXIDE AND ADRENOMEDULLIN IN AUTISM. CELL BIOCHEM FUNCT 2003; 21(1):55-60. 65. YILDIRIM Z, SOGUT S, ODACI E, IRAZ M, OZYURT H, KOTUK M, AKYOL O. ORAL ERDOSTEINE ADMINISTRATION ATTENUATES CISPLATIN-INDUCED RENAL TUBULAR DAMAGE IN RATS. PHARMACOL RES 2003; 47(2):149-56.

66. HEPSEN IF, UZ E, SOGUT S, AKYOL O. EARLY CONTRAST SENSITIVITY LOSS AND OXIDATIVE DAMAGE IN HEALTHY HEAVY SMOKERS. NEUROSCI RES COMMUN 2003; 32:123-133. 67. OZEROL E, ASLAN M, GULEC M, YAKINCI C, AKYOL O. THE EFFECT OF LONG-TERM THERAPY WITH SODIUM VALPROATE ON OXIDANT/ANTIOXIDANT STATUS IN EPILEPTIC CHILDREN. NEUROSCI RES COMMUN 2003; 32:115-122. 68. SASMAZ S, UZ E, PINAR T, VURAL H, EGRI M, ILHAN A, AKYOL O. HAIR LEAD AND CADMIUM CONCENTRATIONS IN PATIENTS WITH EPILEPSY AND MIGRAINE. NEUROSCI RES COMMUN 2003; 32:107-114. 69. IRMAK MK, FADILLIOGLU E, GULEC M, ERDOGAN H, YAGMURCA M, AKYOL O. EFFECTS OF ELECTROMAGNETIC RADIATION FROM A CELLULAR TELEPHONE ON THE OXIDANT AND ANTIOXIDANT LEVELS IN RABBITS. CELL BIOCHEM FUNCT 2002; 20(4):279-83. 70. AKYOL O, HERKEN H, UZ E, FADILLIOGLU E, UNAL S, SOGUT S, OZYURT H, SAVAS HA. THE INDICES OF ENDOGENOUS OXIDATIVE AND ANTIOXIDATIVE PROCESSES IN PLASMA FROM SCHIZOPHRENIC PATIENTS. THE POSSIBLE ROLE OF OXIDANT/ANTIOXIDANT IMBALANCE. PROG NEUROPSYCHOPHARMACOL BIOL PSYCHIATRY 2002; 26(5):995-1005. 71. SOGUT S, AYDIN E, ELYAS H, AKSOY N, OZYURT H, TOTAN Y, AKYOL O. THE ACTIVITIES OF SERUM ADENOSINE DEAMINASE AND XANTHINE OXIDASE ENZYMES IN BEHCET'S DISEASE. CLIN CHIM ACTA 2002; 325(1-2):133-8. 72. UZ E, SOGUT S, SAHIN S, VAR A, OZYURT H, GULEC M, AKYOL O. THE PROTECTIVE ROLE OF CAFFEIC ACID PHENETHYL ESTER (CAPE) ON TESTICULAR TISSUE AFTER TESTICULAR TORSION AND DETORSION. WORLD J UROL 2002; 20(4):264-70. 73. ZOROGLU SS, HERKEN H, YUREKLI M, UZ E, TUTKUN H, SAVAS HA, BAGCI C, OZEN ME, CENGIZ B, CAKMAK EA, DOGRU MI, AKYOL O. THE POSSIBLE PATHOPHYSIOLOGICAL ROLE OF PLASMA NITRIC OXIDE AND ADRENOMEDULLIN IN SCHIZOPHRENIA. J PSYCHIATR RES 2002; 36(5):309-15. 74. SAVAS HA, HERKEN H, YUREKLI M, UZ E, TUTKUN H, ZOROGLU SS, OZEN ME, CENGIZ B, AKYOL O. POSSIBLE ROLE OF NITRIC OXIDE AND ADRENOMEDULLIN IN BIPOLAR AFFECTIVE DISORDER. NEUROPSYCHOBIOLOGY 2002; 45(2):57-61. 75. SAHIN S, SOGUT S, OZYURT H, UZ E, ILHAN A, AKYOL O. TISSUE XANHINE OXIDASE ACTIVITY AND NITRIC OXIDE LEVEL AFTER SPINAL CORD ISCHEMIA/REPERFUSION INJURY IN RABBITS: COMPARISON OF CAFFEIC ACID PHENETHYL ESTER (CAPE) AND METHYLPREDNISOLONE. NEUROSCI RES COMMUN 2002; 31:111-121. 76. AKYOL O. INCREASED LIPID PEROXIDATION IN SCHIZOPHRENIA: A MARKER OF MEMBRANE BREAKDOWN. EUR PSYCHIAT 2002 (SUPPLEMENT 1); 17:75S. 77. OZYURT H, IRMAK MK, AKYOL O, SOGUT S. CAFFEIC ACID PHENETHYL ESTER CHANGES THE INDICES OF OXIDATIVE STRESS IN SERUM OF RATS WITH RENAL ISCHAEMIA-REPERFUSION INJURY. CELL BIOCHEM FUNCT 2001; 19(4):259-63. 78. TOTAN Y, CEKIC O, BORAZAN M, UZ E, SOGUT S, AKYOL O. PLASMA MALONDIALDEHYDE AND NITRIC OXIDE LEVELS IN AGE RELATED MACULAR DEGENERATION. BR J OPHTHALMOL 2001; 85(12):1426-8. 79. HERKEN H, UZ E, OZYURT H, AKYOL O. RED BLOOD CELL NITRIC OXIDE LEVELS IN PATIENTS WITH SCHIZOPHRENIA. SCHIZOPHR RES 2001; 52(3):289-90. 80. KOLTUKSUZ U, MUTUS HM, KUTLU R, OZYURT H, CETIN S, KARAMAN A, GURBUZ N, AKYOL O, AYDIN NE. EFFECTS OF CAFFEIC ACID PHENETHYL ESTER AND EPIDERMAL GROWTH FACTOR ON THE DEVELOPMENT OF CAUSTIC ESOPHAGEAL STRICTURE IN RATS. J PEDIATR SURG 2001; 36(10):1504-9. 81. IRMAK MK, KOLTUKSUZ U, KUTLU NO, YAGMURCA M, OZYURT H, KARAMAN A, AKYOL O. THE EFFECT OF CAFFEIC ACID PHENETHYL ESTER ON ISCHEMIA-REPERFUSION INJURY IN COMPARISON WITH ALPHA-TOCOPHEROL IN RAT KIDNEYS. UROL RES 2001; 29(3):190-3. 82. AKYOL O, OZBEK E, UZ E, KOCAK I. MALONDIALDEHYDE LEVEL AND TOTAL SUPEROXIDE DISMUTASE ACTIVITY IN SEMINAL FLUID FROM PATIENTS WITH VARICOCELE. CLIN EXP MED 2001; 1(1):67-8.

83. AKYOL O, GOKBULUT I, KOKSAL N, AKIN H, OZYURT H, YILDIRIM Z. THE ACTIVITIES OF PURINE CATABOLIZING ENZYMES IN PLASMA AND BRONCHIAL WASHING FLUID IN PATIENTS WITH LUNG CANCER AND PNEUMONIA. CLIN BIOCHEM 2001; 34(3):251-4. 84. HERKEN H, UZ E, OZYURT H, SOGUT S, VIRIT O, AKYOL O. EVIDENCE THAT THE ACTIVITIES OF ERYTHROCYTE FREE RADICAL SCAVENGING ENZYMES AND THE PRODUCTS OF LIPID PEROXIDATION ARE INCREASED IN DIFFERENT FORMS OF SCHIZOPHRENIA. MOL PSYCHIATRY 2001; 6(1):66-73. 85. AKYOL O, ISCI N, TEMEL I, OZGOCMEN S, UZ E, MURAT M, BUYUKBERBER S. THE RELATIONSHIPS BETWEEN PLASMA AND ERYTHROCYTE ANTIOXIDANT ENZYMES AND LIPID PEROXIDATION IN PATIENTS WITH RHEUMATOID ARTHRITIS. JOINT BONE SPINE 2001; 68:311-317. 86. KOLTUKSUZ U, IRMAK MK, KARAMAN A, UZ E, VAR A, OZYURT H, AKYOL O. TESTICULAR NITRIC OXIDE LEVELS AFTER UNILATERAL TESTICULAR TORSION/DETORSION IN RATS PRETREATED WITH CAFFEIC ACID PHENETHYL ESTER. UROL RES. 2000; 28(6):360-3. 87. KOLTUKSUZ U, UZ E, OZEN S, AYDINC M, KARAMAN A, AKYOL O. PLASMA SUPEROXIDE DISMUTASE ACTIVITY AND MALONDIALDEHYDE LEVEL CORRELATE WITH THE EXTENT OF ACUTE APPENDICITIS. PEDIATR SURG INT 2000; 16(8):559-61. 88. VURAL H, UZUN K, UZ E, KOCYIGIT A, CIGLI A, AKYOL O. CONCENTRATIONS OF COPPER, ZINC AND VARIOUS ELEMENTS IN SERUM OF PATIENTS WITH BRONCHIAL ASTHMA. J TRACE ELEM MED BIOL 2000; 14(2):88-91. 89. ILHAN A, UZ E, VAR A, KALI S, AKYOL O. DIAGNOSTIC ROLE OF HAIR MAGNESIUM IN MIGRAINE PATIENTS: HIGHER THAN SERUM MAGNESIUM? TRACE ELEM ELECTROL 2000; 17:14-18. 90. ILHAN A, KOLTUKSUZ U, OZEN S, UZ E, CIRALIK H, AKYOL O. THE EFFECTS OF CAFFEIC ACID PHENETHYL ESTER (CAPE) ON SPINAL CORD ISCHEMIA/REPERFUSION INJURY IN RABBITS. EUR J CARDIOTHORAC SURG 1999; 16(4):458-63. 91. KOLTUKSUZ U, OZEN S, UZ E, AYDINC M, KARAMAN A, GULTEK A, AKYOL O, GURSOY MH, AYDIN E. CAFFEIC ACID PHENETHYL ESTER PREVENTS INTESTINAL REPERFUSION INJURY IN RATS. J PEDIATR SURG 1999; 34(10):1458-62. 92. ILHAN A, UZ E, KALI S, VAR A, AKYOL O. SERUM AND HAIR TRACE ELEMENT LEVELS IN PATIENTS WITH EPILEPSY AND HEALTHY SUBJECTS: DOES THE ANTIEPILEPTIC THERAPY AFFECT THE ELEMENT CONCENTRATIONS OF HAIR? EUR J NEUROL 1999; 6(6):705-9. 93. YILDIRIM Z, HASANOGLU HC, AKYOL O, GOKIRMAK M, KOKSAL N. SERUM ADENOSINE DEAMINASE ACTIVITIES IN LUNG CANCER AND MESOTHELIOMA. CLIN BIOCHEM 1999; 32(4):283-5. 94. CEKIC O, BARDAK Y, TOTAN Y, AKYOL O, ZILELIOGLU G. SUPEROXIDE DISMUTASE, CATALASE, GLUTATHIONE PEROXIDASE AND XANTHINE OXIDASE IN DIABETIC RAT LENSES. OPHTHALMIC RES 1999;31(5):346-50. 95. CEKIC O, BARDAK Y, TOTAN Y, KAVAKLI S, AKYOL O, OZDEMIR O, KAREL F. NICKEL, CHROMIUM, MANGANESE, IRON AND ALUMINUM LEVELS IN HUMAN CATARACTOUS AND NORMAL LENSES. OPHTHALMIC RES 1999; 31(5):332-6. 96. SASMAZ S, SENOL M, OZCAN A, DOGAN G, TUNCER C, AKYOL O, SENER S. THE RISK OF CORONARY HEART DISEASE IN MEN WITH ANDROGENETIC ALOPECIA. J EUR ACAD DERMATOL VENEREOL 1999; 12(2):123-5. 97. BUYUKBERBER S, SENCAN O, BUYUKBERBER N, TUNCER C, AKYOL O, TURGAY M, KOCAKAVAK C. SERUM IMMUNOGLOBULIN E (IG E) LEVELS AFTER MYOCARDIAL INFARCTION. ACTA CARDIOL 1997; 52(4):335-45. 98. AKYOL O, ERSAN F, AKCAY F, ALTUNTAS I, SENOL M, SASMAZ S, YASAR A. HAIR, NAIL, SERUM AND URINE COPPER LEVELS IN USERS OF COPPER INTRAUTERINE DEVICES AND INTERACTIONS BETWEEN COPPER AND SOME OTHER TRACE ELEMENTS. TRACE ELEM ELECTROL 1997; 14:124-9. 99. BUYUKBERBER S, AKYOL O, KAVUTCU M, DURAK I, AYDOGDU I, UYSAL A. ACTIVITIES OF ADENOSINE DEAMINASE, XANTHINE OXIDASE AND SUPEROXIDE DISMUTASE ENZYMES IN SERA AND CEREBROSPINAL FLUIDS FROM PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA. BLOOD 1996; 88 (PART 2 SUPPL):3382-3382.

100. AKYOL O, ARSLANOGLU R, DURAK I. ACTIVITIES OF FREE RADICAL AND DNA TURN-OVER ENZYMES IN CANCEROUS AND NONCANCEROUS HUMAN BRAIN TISSUES. REDOX REP 1995;1:255-9. 101. DURAK I, SAHIN YN, ES MU, AKYOL O, CANBOLAT O, KAVUTÇU M. MAJOR AND MINOR ELEMENT STRUCTURE OF CORONARY ARTERIAL PLAQUES. TRACE ELEM ELECTROL 1994;11: 199-200. 102. CANBOLAT O, AKYOL O, KAVUTCU M, ISIK AU, DURAK I. SERUM ADENOSINE DEAMINASE AND TOTAL SUPEROXIDE DISMUTASE ACTIVITIES BEFORE AND AFTER SURGICAL REMOVAL OF CANCEROUS LARYNGEAL TISSUE. J LARYNGOL OTOL 1994; 108(10):849-51. 103. DURAK I, BUYUKBERBER S, AKYOL O, CANBOLAT O, KAVUTCU M, TUNC E. GLUTATHIONE PEROXIDASE ACTIVITIES IN SERUM AND CEREBROSPINAL FLUID FROM PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA. AM J HEMATOL 1994; 46(3):254. 104. DURAK I, PERK H, KAVUTCU M, CANBOLAT O, AKYOL O, BEDUK Y. ADENOSINE DEAMINASE, 5'NUCLEOTIDASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, AND CATALASE ACTIVITIES IN CANCEROUS AND NONCANCEROUS HUMAN BLADDER TISSUES. FREE RADIC BIOL MED 1994; 16(6):825-31. 105. DURAK I, ORMECI N, AKYOL O, CANBOLAT O, KAVUTCU M, BULBUL M. ADENOSINE DEAMINASE, 5'-NUCLEOTIDASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, AND CATALASE ACTIVITIES IN GASTRIC JUICES FROM PATIENTS WITH GASTRIC CANCER, ULCER, AND ATROPHIC GASTRITIS. DIG DIS SCI 1994; 39(4):721-8. 106. DURAK I, KAVUTCU M, CANBOLAT O, ISIK AU, AKYOL O. CONCENTRATIONS OF SOME MAJOR AND MINOR ELEMENTS IN LARYNX TISSUES WITH AND WITHOUT CANCER. BIOMETALS 1994; 7(1):45-8. 107. DURAK I, AKYOL O, BASESME E, CANBOLAT O, KAVUTCU M. REDUCED ERYTHROCYTE DEFENSE MECHANISMS AGAINST FREE RADICAL TOXICITY IN PATIENTS WITH CHRONIC RENAL FAILURE. NEPHRON. 1994; 66(1):76-80. 108. KITAPCI F, DILMEN U, AKYOL O, TOPPARE M, KAYA IS, SENSES DA, DURAK I, KILIC Z. PLASMA CHROMIUM LEVELS IN HYPOGLYCEMIC PRETERM, FULL-TERM AND IN INTRAUTERINE-GROWTH-RETARDED BABIES. BIOL NEONATE 1994; 66(5):267-71. 109. DURAK I, BUYUKBERBER S, AKYOL O, CANBOLAT O, KAVUTÇU M, TUNC E. GLUTATHIONE PEROXIDASE ACTIVITIES IN SERUM AND CEREBROSPINAL FLUID FROM PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA. AM J HEMATOL 1994; 46: 254. 110. DURAK I, ONDER E, DEMIR TA, CANBOLAT O, AKYOL O, ES MU, SAHIN YN. TOXIC TRACE ELEMENT CONTENT OF CORONARY ARTERY PLAQUES. TRACE ELEM ELECTROL 1994; 11: 172-173. 111. DURAK I, ISIK AC, CANBOLAT O, AKYOL O, KAVUTCU M. ADENOSINE DEAMINASE, 5' NUCLEOTIDASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, AND CATALASE ACTIVITIES IN CANCEROUS AND NONCANCEROUS HUMAN LARYNGEAL TISSUES. FREE RADIC BIOL MED 1993; 15(6):681-4. 112. AKYOL O, SENCAN O, BUYUKBERBER S, CANBOLAT O, DURAK I. GLUTATHIONE PEROXIDASE ACTIVITY IN SERUM DURING ACUTE MYOCARDIAL INFARCTION AND UNSTABLE ANGINA PECTORIS. JPN HEART J 1993; 34(5):551-5. 113. DURAK I, AKYOL O, CANBOLAT O, BUYUKBERBER S, SENCAN O. MN- AND CU,ZN-SUPEROXIDE DISMUTASE ACTIVITIES DURING ACUTE MYOCARDIAL INFARCTION. CLIN CHEM 1993; 39(5):911-2. 114. DURAK I, AKYOL O, ES MU, CANBOLAT O, AKPOYRAZ M. ELEMENT STRUCTURE IN STENOTIC MITRAL VALVES. AM J CARDIOL 1993; 71(4):355. 115. DURAK I, YURTARSLANL Z, CANBOLAT O, AKYOL O. A METHODOLOGICAL APPROACH TO SUPEROXIDE DISMUTASE (SOD) ACTIVITY ASSAY BASED ON INHIBITION OF NITROBLUE TETRAZOLIUM (NBT) REDUCTION. CLIN CHIM ACTA 1993; 214(1):103-4.

ULUSAL HAKEMLİ DERGİLER KAPSAMINDAKİ YAYINLAR

1. SAVAŞ HA, GERGERLIOĞLU HS, GÜREL A, SELEK S, SAVAŞ E, KOÇOĞLU E, ÖZEN ME, HERKEN

H, AKYOL Ö. İKIUÇLU BOZUKLUK HASTALARINDA ÖTIMIK EVREDE ARTMIŞ KSANTIN OKSIDAZ VE MALONDIALDEHIT DÜZEYLERI. KLINIK PSIKIYATRI DERGISI 2005; 8:180-5.

2. OZYURT H, GOKBULUT I, OZUGURLU F, KOKSAL N, SOGUT S, AKYOL O. RED BLOOD CELL OXIDANT/ANTIOXIDANT STATUS IN PATIENTS WITH LUNG CANCER AND PNEUMONIA. TURKISH J HEMATOL ONCOL 2004; 14:185-92.

3. AKYOL Ö. ŞIZOFRENIDE OKSIDATIF STRES. KOCATEPE TIP DERGISI 2004; 5 (EK SAYI):15-25. 4. YILMAZ HR, IŞIK B, GÜLEÇ M, SÖĞÜT S, AKYOL Ö. SISPLATININ BÖBREK METABOLIZMASI

ÜZERINE ETKILERI: GINKGO BILOBA EKSTRAKTININ KORUYUCULUĞU. TÜRK HEMATOLOJI ONKOLOJI DERGISI 2004; 14:20-4.

5. KALCIOĞLU MT, KIZILAY A, YILMAZ HR, UZ E, GÜLEÇ M, ÖZTURAN O, AKYOL Ö. ADENOSINE DEAMINASE, XANTHINE OXIDASE, SUPEROXIDE DISMUTASE, GLUTATHIONE PEROXIDASE ACTIVITIES AND MALONDIALDEHYDE LEVELS IN SERUM OF PATIENTS WITH HEAD AND NECK CARCINOMA. KBB İHTISAS DERGISI 2004; 12:16-22.

6. YILMAZ HR, SOGUT S, OZYURT H, IRAZ M, YILDIRIM Z, AKYOL Ö. SIÇANLARDA SISPLATIN ILE OLUŞTURULAN NEFROTOKSISITEDE METABOLIK ENZIM AKTIVITELERINE KAFEIK ASIT FENETIL ESTERIN ETKISI. VAN TIP DERGISI 2004; 11:1-6.

7. AKYOL Ö, ÜNAL S. SINAPS DIŞI ILETI. KLINIK PSIKOFARMAKOLOJI BÜLTENI 2003; 13:195-201. 8. SARSILMAZ M, YILMAZ HR, SONGUR A, TÜRKOĞLU AÖ, AKYOL Ö. BALIK OMEGA-3 YAĞ

ASITLERININ SIÇAN TESTISINDE BAZI METABOLIK ENZIM AKTIVITELERI ÜZERINE ETKISI. FIRAT TIP DERGISI 2003; 8:83-6.

9. MEHMET N, TEVFIK MR, ALADAĞ M, KARAGÖZLER A, AKYOL Ö, GÖZÜKARA E. MIDE KANSERLI HASTALARIN MIDE SULARINDA SÜPEROKSIT DISMUTAZ, KATALAZ VE GLUTATYON PEROKSIDAZ AKTIVITELERI VE MALONDIALDEHIT SEVIYELERI. KLINIK LABORATUVAR ARAŞTIRMA DERGISI 2003; 7:39-43.

10. UZ E, YILMAZ HR, IRAZ M, FADILLIOĞLU E, ÖZYURT H, SÖĞÜT S, AKYOL Ö. DENEYSEL KARACIĞER ISKEMI-REPERFÜZYON OLUŞTURULAN SIÇANLARDA E VITAMINI VE KAFEIK ASIT FENETIL ESTERIN (CAPE) METABOLIK ENZIMLERE ETKISI. EGE TIP DERGISI, 2002; 41:77-82.

11. GÖKBULUT İ, ÖZYURT H, KÖKSAL N, YILDIRIM Z, AKYOL Ö. AKCIĞER KANSERI VE PNÖMONI HASTALARININ BRONŞIAL YIKAMA SIVISI ILE PLAZMALARINDA NITRIK OKSIT (NO) VE MALONDIALDEHIT (MDA) DÜZEYLERI. OPTIMAL TIP DERGISI 2002; 15: 72-8.

12. TEMEL İ, ÖZEROL E, BAY A, ÇIĞLI A, AKYOL Ö. ERYTHROCYTE CATALASE ACTIVITIES IN ALCOHOL CONSUMPTION, MEDICATIONS AND SOME DISEASES IN HUMANS. İNÖNÜ ÜNIVERSITESI TIP FAKÜLTESI DERGISI 2002;9:11-4.

13. BAY KARABULUT A, ÖZEROL E, TEMEL İ, GÖZÜKARA EM, AKYOL Ö. YAŞ VE SIGARA IÇIMININ ERITROSIT KATALAZ AKTIVITESI VE BAZI HEMATOLOLOJIK PARAMETRELER ÜZERINE ETKISI. İNÖNÜ ÜNIVERSITESI TIP FAKÜLTESI DERGISI 2002; 9:85-8.

14. KOLTUKSUZ U, UZ E, KARAMAN A, ÖZYURT H, AYDINÇ M, AKYOL Ö. DETORSIYON ÖNCESI UYGULANAN CAFFEIC ACID PHENETHYL ESTER’IN TESTIKÜLER REPERFÜZYON HASARINA ETKISI. KLINIK BILIMLER & DOCTOR 2000; 6:633-636.

15. AKYOL Ö, GÜREL A, AKIN H. 17-ß-ESTRADIOL VE 7,12-DIMETHYLBENZ(A)ANTHRACENE ILE MUAMELE EDILMIŞ MCF-10A HÜCRE KÜLTÜRÜNDE MAJOR ANTIOKSIDAN ENZIMLERIN DURUMU: BIR ÖN ÇALIŞMA. TÜRK HEMATOLOJI ONKOLOJI DERGISI 2000; 10:207-11.

16. AKYOL Ö, UZ E, ÖZEROL E. VÜCUTTAKI TAMPON SISTEMLER VE ASIDOZ-ALKALOZ TEDAVISINDE TEMEL ILKELER. MALATYA TABIP ODASI DERGISI 1999; 1:58-61.

17. AKYOL Ö, TEMEL İ., SEZGIN N. KLINIK ENZIMOLOJI: HANGI TEST NE ZAMAN ISTENMELI? MALATYA TABIP ODASI DERGISI 1999; 1:40-3.

18. KOLTUKSUZ U, UZ E, GÜRSOY H, DEMIRCAN M, AYDINÇ M, MUTUŞ M, ÇETIN S, KARAMAN A, AKYOL Ö. AKUT APANDISITTE PLAZMA VE ERITROSIT SÜPEROKSIT DISMUTAZ AKTIVITELERI. PEDIATRIK CERRAHI DERGISI, 1998; 12:19-22.

19. ÇEKIÇ O, BARDAK Y, AKYOL Ö, TOTAN Y, ZILELIOĞLU G. DIABETIK SIÇAN LENSLERINDE KALSIYUM, MAGNEZYUM, DEMIR DEĞERLERI VE VERAPAMILIN ETKISI. YENI TIP DERGISI 1995; 12:28-31.

20. ÖZTÜRK HS, KAVUTÇU M, AKYOL Ö, IŞIK AÜ, CANBOLAT O. LARENKS KANSERLI HASTALARIN SERUMLARINDA GUANAZ VE GLUTATYON PEROKSIDAZ AKTIVITELERININ TAYINI. TÜRKIYE TIP DERGISI 1994; 1:15-8.

21. SOLMAZ NU, AKYOL Ö, KURAL G. DIABETIK RATLARDA KATARAKT GELIŞIMI ÜZERINE VERAPAMILIN ETKISI. TURK OFT GAZ 1993; 23:261-5.

22. CANBOLAT O, AKYOL Ö, KAVUTÇU M, YURTARSLANI Z, DURAK İ. SÜPEROKSIT DISMUTAZ (SOD) AKTIVITESININ TAYINI ÜZERINE DENEYSEL BIR ÇALIŞMA. ANKARA TIP MECMUASI 1993; 46:75-84.

23. AKYOL Ö, KAVUTÇU M, CANBOLAT O, ÖRMECI N, DURAK İ. MIDE SUYUNDA 5' NÜKLEOTIDAZ (5NT) VE CU,ZN SÜPEROKSIT DISMUTAZ (SOD) ENZIMLERININ AKTIVITELERI ÜZERINE

SICAKLIK VE ZAMANIN ETKISI: DENEYSEL BIR ÇALIŞMA. ANKARA TIP MECMUASI 1993; 46:581-90.

24. AKYOL Ö, ŞENCAN O, DURAK İ. SUPRADYN TEDAVISININ SAÇ, TIRNAK, SERUM VE IDRARDAKI BAZI ESER ELEMENTLERIN SEVIYESI ÜZERINE ETKISI: BIR VAKA ÇALIŞMASI. TURK J DERMATOL 1992; 2:65-7.

25. AKYOL Ö, CANBOLAT O, BAŞEŞME E. KRONIK BÖBREK YETMEZLIĞINDE UYGULANAN TEDAVILERIN ERITROSIT SÜPEROKSIT DISMUTAZ VE GLUTATYON PEROKSIDAZ ENZIMLERININ AKTIVITELERI ÜZERINE OLAN ETKILERININ ARAŞTIRILMASI. TR J MED SCI 1992; 16:861-6.

26. BÜYÜKBERBER S, AKYOL Ö, KAVUTÇU M, DURAK İ, AYDOĞDU İ. ACTIVITIES OF ADENOSINE DEAMINASE, XANTHINE OXIDASE AND SUPEROXIDE DISMUTASE ENZYMES IN SERA AND CEREBROSPINAL FLUIDS FROM PATIENTS WITH ACUTE LYMPHOCYTIC LEUKEMIA. TR J CANCER 1996; 26:97-103.

27. BALCI M, AKYOL Ö, ZENGIN N, KURAL G. ANTIOXIDANT ENZYME STATUS IN ALLOXAN-DIABETIC RAT LENSES. TR J MED RES 1994; 12:1-4.

28. ZENGIN N, AKYOL Ö, BALCI M, DURAK İ. XANTHINE OXIDASE IN HUMAN LENS. ITS POSSIBLE ROLE IN CATARACTOGENESIS. TR J MED SCI 1994; 20:91-3.

29. AKYOL Ö, KAVUTÇU M, CANBOLAT O, DURAK İ. A STUDY ON THE RELATIONSHIPS BETWEEN SOME OF THE TRACE ELEMENT LEVELS OF HAIR, NAIL, SERUM AND URINE IN HEALTHY SUBJECTS. TR J MED RES 1993; 11:75-81.

30. ŞAFAK MA, AKYOL Ö, DERE H, ÖZERI C, ERYILMAZ A, SAMIM E, DURAK İ. ADENOSINE DEAMINASE (ADA) AND 5' NUCLEOTIDASE (5NT) ACTIVITIES IN CARCINOMAS OF LARYNX. J TURK HEMATOL ONKOL 1993; 3:42-4.

31. DURAK İ, CANBOLAT O, KAVUTÇU M, AKYOL Ö. QUANTİTATİVE ELEMENT ANALYSİS İN NUCLEUS AND CRUST PARTS OF CHOLESTEROL GALLSTONES. J ANKARA MED SCH 1992; 14:399-404.

ULUSLARARASI KONGRE BİLDİRİLERİ

1. Ö. Akyol, İ. Durak, O. Canbolat, H. Perk, M. Kavutçu, Y. Bedük. Establishment of adenosine deaminase, 5' nucleotidase, xanthine oxidase, superoxide dismutase and catalase activities in cancerous and non-cancerous human bladder tissues. International Congress on Trace Elements in Medicine and Biology. April 5th-9th 1993, Chamonix-France.

2. Z. Yıldırım, H.C. Hasanoglu, Ö. Akyol, M. Gökırmak. Serum adenosine deaminase activities in lung cancer and mesothelioma. ERS (European Respiratory Society) Annual Congress. Geneva, Switzerland, September 19-23, 1998.

3. İ. Temel, Y. Türköz, A. Çığlı, Ö. Akyol. A correlation between glycosylated hemoglobin and serum lipid concentrations in NIDDM. Turkish Biochemical Society & Balkan Association of Biosciences. The First International Biosciences Days, The First Congress of Balkan Association of Biosciences, XVth National Congress of Biochemistry, Clinical Laboratory Automation Symposium-II. April 20-24, 1999, Sirene Hotel, Antalya, Turkey.

4. U. Koltuksuz, E. Uz, Ö. Akyol, H. Gürsoy, S. Çetin, A. Karaman. Plasma and erythrocyte superoxide dismutase activities and malondialdehyde levels in patients with acute appendicitis. Turkish Biochemical Society & Balkan Association of Biosciences. The First International Biosciences Days, The First Congress of Balkan Association of Biosciences, XVth National Congress of Biochemistry, Clinical Laboratory Automation Symposium-II. April 20-24, 1999, Sirene Hotel, Antalya, Turkey.

5. Ö. Akyol, U. Koltuksuz, S. Özen, E. Uz, A, Karaman, H. Gürsoy, H. Ünlü. Caffeic acid phenethyl ester (CAPE) prevents intestinal ischemia/reperfusion injury in rats. Turkish Biochemical Society & Balkan Association of Biosciences. The First International Biosciences Days, The First Congress of Balkan Association of Biosciences, XVth National Congress of Biochemistry, Clinical Laboratory Automation Symposium-II. April 20-24, 1999, Sirene Hotel, Antalya, Turkey.

6. E. Uz, N. İşçi, M. Harputluoğlu, A. Çığlı, İ. Temel, Ö. Akyol, Y. Türköz, M. Murat. The relationship between plasma and erythrocyte antioxidant enzymes and lipid peroxidation in patients with rheumatoid arthritis. Turkish Biochemical Society & Balkan Association of Biosciences. The First International Biosciences Days, The First Congress of Balkan Association of Biosciences, XVth National Congress of Biochemistry, Clinical Laboratory Automation Symposium-II. April 20-24, 1999, Sirene Hotel, Antalya, Turkey.

7. E. Uz, F. Armutçu, İ. Temel, A. Çığlı, Ö. Akyol, S. Söğüt, H. Özyurt, A. Aker. Lipid peroxidation and antioxidant status in iron miners. Turkish Biochemical Society & Balkan Association of Biosciences. The First International Biosciences Days, The First Congress of Balkan Association of Biosciences, XVth National Congress of Biochemistry, Clinical Laboratory Automation Symposium-II. April 20-24, 1999, Sirene Hotel, Antalya, Turkey.

8. Ö. Akyol, U. Koltuksuz, E. Uz, A. Karaman, A. Var, H. Özyurt, S. Söğüt. The effects of caffeic acid phenethyl ester (CAPE) on free radical scavenging enzymes in rat testicular tissues after unilateral testicular torsion/detorsion. BCLF’99 7th Meeting of the Balkan Clinical Laboratory Federation, November 4-7, 1999, Letoonia Golf Resort, Antalya-TURKEY.

9. Ö. Akyol, H. Özyurt, S. Söğüt, M.K. Irmak. Caffeic acid phenethyl ester changes the indices of oxidative stress in serum of rats with renal ischemia-reperfusion injury. XVIth National Congress of Biochemistry. The Second International Biosciences Days. October 23-27, 2000, Selçuk-İzmir-TURKEY.

10. S. Ozgocmen, O. Ardıcoglu, S. Sogut, I. Pekkutucu, E. Fadillioglu, O. Akyol. Serum nitric oxide, catalase, superoxide dismutase, xanthine oxidase and malondialdehyde status in patients with ankylosing spondylitis. Annual European Congress of Rheumatology, EULAR 2001, 13-16 June 2001, Prague.

11. Söğüt S, Elyas H, Erdinç A, Aksoy N, Özyurt H, Totan Y, Akyol Ö. Adenosine deaminase and xanthine oxidase activities in serum from patients with Behcet’s disease. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

12. Gökbulut İ, Özyurt H, Köksal N, Akın H, Yıldırım Z, Akyol Ö. The activities of furine catabolizing enzymes in plasma and bronchial washing fluid in patients with lung cancer and pneumonia. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

13. Uz E, Ağkadir M, Erdoğan H, Fadıllıoğlu E, Söğüt S, Özyurt H, Akyol Ö. The oxidant and antioxidant enzyme activities of rat liver after experimental ischemia-reperfusion: the effects of vitamin E and caffeic acid phenethyl ester (CAPE) on tissue injury. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

14. Söğüt S, Özyurt H, Şahin Ş, Güleç M, Irmak MK, Akyol Ö. Effects of alpha-tocopherol and caffeic acid phenethyl ester via nitric oxide generation on ischemia-reperfusion injury in rat kidneys. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

15. Irmak MK, Yağmurca M, Koltuksuz U, Kutlu NO, Özyurt H, Karaman A, Akyol O. The effects of caffeic acid phenethyl ester on ischemia-reperfusion injury in comparison with alpha-tocopherol in rat kidneys. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

16. Irmak MK, Güleç M, Fadıllıoğlu E, Erdoğan H, Yağmurca M, Akyol Ö. The effects of electromagnetic radiation from a cellular phone on the oxidant and antioxidant levels in rabbits. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

17. Özyurt H, Totan A, Kılınç C, Şahin Ş, Söğüt S, Akyol O. Maternal serum and amnion fluid OH-prolin levels in neural tube defects. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

18. Uz E, Ağkadir M, Fadıllıoğlu E, Erdoğan H, Özyurt H, Söğüt S, Akyol Ö. The serum indices of experimental liver ischemia-reperfusion injury in rats treated with caffeic acid phenethyl ester (CAPE) and vitamin E. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

19. Uz E, Hepşen İF, Var A, Şahin Ş, Akyol Ö. The relationships between serum trace element changes and visual functions in heavy smokers. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

20. Hepşen İF, Uz E, Uğurcu V, Büyükbaş S, Söğüt S, Akyol Ö. Early contrast sensitivity loss and oxidative damage in healthy heavy smokers. 9th Meeting of Balkan Clinical Laboratory Federation (BCLF), September 12-15, 2001, Ioannina, Greece.

21. Özerol E, İlhan A, Güleç M, İlhan N, Ulvi H, İlhan N, Akyol Ö. The levels of trace lelements functioning as prostetic groups of superoxide dismutase in patients with epilepsy. 2nd International Meeting on Free Radicals in Health and Disease. The Role of Oxidants and Antioxidants in the regulation of Chronic Diseases. May 8-12, 2002 İstanbul, TURKEY.

22. Özerol E, Ulvi H, İlhan N, Güleç M, İlhan A, İlhan N, Akyol Ö. Determination of copper, zinc and manganese in nail and serum of patients with migraine. 2nd International Meeting on Free Radicals in Health and Disease. The Role of Oxidants and Antioxidants in the regulation of Chronic Diseases. May 8-12, 2002 İstanbul, TURKEY.

23. Güleç M, Özcan ME, Özerol E, Polat R, Akyol Ö. Free radical scavenging enzyme activities and some parameters of oxidative stress in patients with affective disorders. 2nd International Meeting on Free Radicals in Health and Disease. The Role of Oxidants and Antioxidants in the regulation of Chronic Diseases. May 8-12, 2002 İstanbul, TURKEY.

24. Sarsilmaz M, Songur A, Kus I, Ozen OA, Ozyurt H, Akyol O. The effects of omega-3 fatty acids diet on some oxidant and antioxidant parameters in rat corpus striatum. 3rd Forum of European Neuroscience,Federation of European Neuroscience Societies (FENS), Paris, 13-17 July, 2002.

25. Yilmaz HR, Sogut S, Ozyurt H, Iraz M, Yildirim Z, Akyol O. The effects of erdosteine and caffeic acid phenethyl ester on the activities of some metabolic enzymes after cicplatin-induced nephrotoxicity in rats. 12th ERS Congress Stockholm, Sweden, September 14-18, 2002. European Respiratory Journal volume 2002;20 (Supplement 38):71s.

26. Yildirim Z, Sogut S, Iraz M, Ozyurt H, Kotuk M, Akyol O. Protective effect of oral erdostein administration on cisplatin-induced nephrotoxicity in rats. 12th ERS Congress Stockholm, Sweden, September 14-18, 2002. European Respiratory Journal volume 2002;20 (Supplement 38): 74s.

27. Ozyurt H, Sogut S, Akyol O, Kart L, Iraz M, Yildirim Z, Armutcu F, Temel I. Inhibitory effect of caffeic acid phenethyl ester on bleomycine-induced lung fibrosis in rats. 12th ERS Congress Stockholm, Sweden, September 14-18, 2002. European Respiratory Journal volume 2002;20 (Supplement 38): 487s

28. Sogut S, Ozyurt H, Akyol O, Kart L, Iraz M, Yildirim Z, Armutcu F, Temel I. Protection of erdosteine on bleomycine-induced lung fibrosis in rats. 12th ERS Congress Stockholm, Sweden, September 14-18, 2002. European Respiratory Journal volume 2002;20 (Supplement 38):487s.

29. Ozerol E, Aslan M, Gulec M, Yakinci C, Akyol O. The effect of long-term therapy with sodium valproate on oxidant/antioxidant status in epileptic children. FEBS (Federation of European Biochemical Societies) 28th International Meeting. October 20-25, 2002, Istanbul Turkey.

30. Akyol O, Sogut S, Ozyurt H, Gurel A, Kart L, Ozugurlu F, Iraz M. Plasma and erytrocyte purine catabolising enzymes in rats with bleomycin-induced lung fibrosis: The protective role of erdosteine. International Conference, American Thoracic Society, May 16-21, Seattle, Washington, USA. American Journal of Respiratory and Critical Care Medicine 2003;167 (Supplement 7): A979.

31. Temel I, Gulec M, Yilmaz R, Iraz M, Sogut S, Ozyurt H, Akyol O. the effects of ginkgo biloba extract on tissue oxidant/antioxidant system in cisplatin nephrotoxicity. 13th Balkan Biochemical Biophysical Days & Meeting on Metabolic Disorders 12-15 October 2003, Kusadasi, TURKEY.

32. Gulec M, Iraz M, Yilmaz R, Ozyurt H, Akyol O, Temel I. The effects of ginkgo biloba extract on tissue adenosine deaminase, xanthine oxidase, myeloperoxidase and malondialdehyde, nitric oxide levels in cisplatin-induced nephrotoxicity. 13th Balkan Biochemical Biophysical Days & Meeting on Metabolic Disorders 12-15 October 2003, Kusadasi, TURKEY.

33. Ozerol E, Gulec M, Fadillioglu E, Iraz M, Aglamis S, Akyol O. the effect of caffeic acid phenethyl ester (CAPE) on cisplatin-induced toxicity in rat liver tissues. 13th Balkan Biochemical Biophysical Days & Meeting on Metabolic Disorders 12-15 October 2003, Kusadasi, TURKEY.

34. Yilmaz HR, Ozyurt H, Sogut S, Kotuk M, Akyol O, Yildirim Z. Effect of caffeic acid phenethyl ester on the activities of hexokinase, glucose-6-phosphate dehydrogenase, lactate dehydrogenase, and malate dehydrogenase in the heart tissue during cisplatin-induced nephrotoxicity model of rats. 5th International Congress of Turkish Society of Toxicology October 30-November 2 2003, Antalya, TURKEY.

35. Yilmaz HR, Sogut S, Ozyurt H, Uz E, Yildirim Z, Akyol O. Effects of oral erdosteine on the activities of some metabolic enzyme in heart tissue during cisplatin-induced nephrotoxicity model of rats. 5th International Congress of Turkish Society of Toxicology October 30-November 2 2003, Antalya, TURKEY.

36. Yilmaz HR, Akyol O, Ozyurt H, Sogut S, Demirel R, Yildirim Z. The effects of antioxidant caffeic acid phenethyl ester (CAPE) on some enzyme activities in the brain after cisplatin-induced nephrotoxicity in rats. 5th International Congress of Turkish Society of Toxicology October 30-November 2 2003, Antalya, TURKEY.

37. Yilmaz HR, Yildirim Z, Sogut S, Ozyurt H, Demirel R, Akyol O. Effects of oral erdosteine on some enzyme activities participating important metabolic pathways in the brain after cisplatin-induce nephrotoxicity in rats. 5th International Congress of Turkish Society of Toxicology October 30-November 2 2003, Antalya, TURKEY.

38. Kizilay A, Kalcioglu MT, Ozerol E, Iraz M, Gulec M, Akyol O, Ozturan O. Caffeic acid phenethyl ester ameliorated ototoxicity induced by cisplatin in rats. World Conference on Magic Bullets Celebrating Paul Ehrlich’s 150th Birthday. Nürnberg, Germany, September 9-11, 2004.

39. Kizilay A, Kalcioglu MT, Ozugurlu F, Ozyurt H, Aladag I, Ozturan O, Akyol O. Nitric oxide levels in the serum of the patients with head and neck squamous cell carcinoma. 3 Congresso Italo-Turco Di Laringologia. Chieti/Pescara, Italia, Ottobre 2004.

40. Tekedereli I, Ilhan A, Yuce H, Isik B, Alacam H, Elyas H, Akyol O. Mitochondrial targeting sequence polymorphism of manganese superoxide dismutase (SOD2) in patients with migraine. 7th Balkan meeting on human genetics BMHG 2006, Skopje, Macedonia.

41. Yuce H, Hepsen F, Tekedereli I, Keskin UC, Elyas H, Akyol O. Lack of association between pseudoexfoliation syndrome and manganese superoxide dismutase polymorphism. 7th Balkan meeting on human genetics BMHG 2006, Skopje, Macedonia.

42. Omer Akyol, Hasan Alacam. Potential pathogenetic role of oxidant/antioxidant system abnormalities in neuropsychiatric disorders. TASSA Annual Conference, Harvard Medical School Conference Center, Boston, Massachussetts, USA, April 11-13, 2008.

43. Hasan Alacam, Omer Akyol. Therapeutic usage of caffeic acid phenethyl ester (CAPE) in ischemia-reperfuion models. TASSA Annual Conference, Harvard Medical School Conference Center, Boston, Massachussetts, USA, April 11-13, 2008.