XTC Neurology

ǀĂĐƵĂƚĞ ƚŚĞ ĂŶĐĞ &ůŽŽƌ ^ŝŶĐĞ ƚŚĞ ƵƐĞ ŽĨ DD ďĞĐĂŵĞ ŝůůĞŐĂů ŝŶ ƚŚĞ h^ ŝŶ ϭϵϴϱ ƐĞǀĞƌĂů ʹ ŽŌĞŶ ŐŽǀĞƌŶŵĞŶƚ ĮŶĂŶĐĞĚͲ ƐƚƵĚŝĞƐ ŚĂǀĞ ďĞĞŶ ĐŽŶĚƵĐƚĞĚ ƚŽ ƉƌŽǀĞ ŝƚƐ ŶĞŐĂƟǀĞ ĞīĞĐƚƐ ŽŶ ƚŚĞ ďƌĂŝŶ /Ŷ ϭϵϵϴ ŶĞƵƌŽůŽŐŝƐƚ 'ĞŽƌŐĞ ZŝĐĂƵƌƚĞ ǁĂƐ ƚŚĞ ĮƌƐƚ ƚŽ ƉƵďůŝƐŚ Ă ƐƚƵĚǇ ŽŶ DD ZŝĐĂƵƌƚĞ ĐůĂŝŵĞĚ ƚŚĂƚ ĐƐƚĂƐǇ ĐĂƵƐĞƐ ďƌĂŝŶ ĚĂŵĂŐĞ ŝŶ ŚƵŵĂŶƐ ƐƵŐŐĞƐƟŶŐ ƚŚĂƚ ŝƚƐ ƵƐĞƌƐ ĐŽƵůĚ ůŽƐĞ ƵƉ ƚŽ ϴϱй ŽĨ ƚŚĞ ďƌĂŝŶƐ ƐĞƌŽƚŽŶŝŶ ĨƵŶĐƟŽŶ hƐŝŶŐ ƚŚĞƐĞ ƌĞƐƵůƚƐ ƚŚĞ h^ ďĞŐĂŶ ŝƚƐ ƌĂŝŶ ŽŶ ĐƐƚĂƐǇ ĐĂŵƉĂŝŐŶ Ǉ ƐƉƌĞĂĚŝŶŐ ƉŽƐƚ ĐĂƌĚƐ ƐŚŽǁŝŶŐ Ă ďƌĂŝŶ ƐĐĂŶ ŽĨ ƚŚĞ DD ďƌĂŝŶ ǁŚŝĐŚ ĂƉƉĞĂƌĞĚ ƚŽ ďĞ ĨƵůů ŽĨ ŚŽůĞƐ ĐƐƚĂƐǇ ƉĂŶŝĐ ĂƌŽƐĞ /Ŷ Ă ĨŽůůŽǁͲƵƉ ƐƚƵĚǇ ZŝĐĂƵƌƚĞ ĂĚĚĞĚ ƚŚĂƚ ƵƐŝŶŐ ƚŚĞ ƉĂƌƚǇ ĚƌƵŐ ʹ ĞǀĞŶ ŽŶĐĞͲ ĐŽƵůĚ ĐĂƵƐĞ WĂƌŬŝŶƐŽŶƐ ĚŝƐĞĂƐĞ But all claims proved to be unfounded. The WĂƌŬŝŶƐŽŶƐ ƐƚƵĚǇ ƉƵďůŝƐŚĞĚ ďǇ ^ĐŝĞŶĐĞ was retracted when researchers discovered ƚŚĂƚ ǀŝĂůƐ ŽĨ DD ŚĂĚ ďĞĞŶ ĂĐĐŝĚĞŶƚĂůůǇ ƐǁŝƚĐŚĞĚ ŽƵƚ ĨŽƌ ŵĞƚŚĂŵƉŚĞƚĂŵŝŶĞ ĂůƐŽ ŬŶŽǁŶ ĂƐ ƌǇƐƚĂů DĞƚŚ DDƐ ůĞƐƐ ĨŽƌŐŝǀ ŝŶŐ ŶĞƉŚĞǁ /Ŷ ϮϬϬϮ ƚŚĞ ƌŝƟƐŚ ŵĂŐĂǌŝŶĞ EĞǁ ^ĐŝĞŶƟƐƚ ĂůƐŽ ƐƚĂƌƚĞĚ ƋƵĞƐƟŽŶŝŶŐ Zŝ ĐĂƵƌƚĞƐ ďŽĚǇ ŽĨ ǁŽƌŬ >ĞĂĚŝŶŐ ŝŶĚĞƉĞŶĚ ent researchers were asked to look at the ĞǀŝĚĞŶĐĞ ĂŶĚ ĂŶƐǁĞƌ ŽŶĞ ƋƵĞƐƟŽŶ ŽĞƐ DD ĚĂŵĂŐĞ ďƌĂŝŶ ĐĞůůƐ EĞǁ ^ĐŝĞŶƟƐƚƐ ĐŽŶĐůƵƐŝŽŶ ǁĂƐ ƚŚĞ ũƵƌǇ ŝƐ ƐƟůů ŽƵƚ EŽ ƌĂŝŶ ĂŵĂŐĞ Ɛ ŽĨ &ĞďƌƵĂƌǇ ϮϬϭϭ ƚŚĞ ũƵƌǇ ƐĞĞŵƐ ƚŽ ŚĂǀĞ ƌĞĂĐŚĞĚ Ă ǀĞƌĚŝĐƚ ,ĂƌǀĂƌĚ hŶŝǀĞƌƐŝƚǇƐ :ŽŚŶ ,ĂůƉĞƌŶ ƌĞĐĞŶƚůǇ ƉƵďůŝƐŚĞĚ Ă ƐƚƵĚǇ ŝŶ ƚŚĞ ŵĞĚŝĐĂů ũŽƵƌŶĂů ĚĚŝĐƟŽŶ ƚŚĂƚ ĞǆĂŵŝŶĞĚ ƚŚĞ ĞīĞĐƚƐ ŽĨ ĐƐƚĂƐǇ ŽŶ ĐŽŐŶŝƟǀĞ ĂďŝůŝƚǇ ,ŝƐ ĐŽŶĐůƵƐŝŽŶ ŚĞĂǀǇ ƌĞĐƌĞĂƟŽŶĂů ĐƐƚĂƐǇ ƵƐĞ ĚŽĞƐ ŶŽƚ ĐĂƵƐĞ ĐŽŐŶŝƟǀĞ ĚĂŵĂŐĞ Halpern and his colleagues compared ϱϮ ůŽŶŐͲƚĞƌŵ ĐƐƚĂƐǇ ƵƐĞƌƐ ĂŐĞĚ ϭϴ ƚŽ ϰϱ ǁŝƚŚ ϱϵ ŶŽŶͲƵƐĞƌƐ Ăůů ŽĨ ǁŚŽŵ ǁĞƌĞ ĚƌƵŐͲ ƚĞƐƚĞĚ ƉƌŝŽƌ ƚŽ ƚŚĞŝƌ ƉĂƌƟĐŝƉĂƟŽŶ ŝŶ ƚŚĞ ƐƚƵĚǇ ƚŽ ĞŶƐƵƌĞ ĂĐĐƵƌĂƚĞ ƌĞƐƵůƚƐ hŶůŝŬĞ ƉƌĞ ǀŝŽƵƐ ƌĞƐĞĂƌĐŚ ŽŶůǇ ƌĂǀĞƌƐ ǁĞƌĞ ƚĞƐƚĞĚ ƚŽ ŵĂŬĞ ƐƵƌĞ ƚŚĂƚ ŽƚŚĞƌ ƐŝĚĞ ĞīĞĐƚƐ ŽĨ ŚĂǀŝŶŐ Ă ƉĂƌƚǇ ůŝĨĞƐƚǇůĞ ʹĨŽƌ ĞǆĂŵƉůĞ ƌĞƉĞĂƚĞĚ ƐůĞĞƉ ĂŶĚ ŇƵŝĚ ĚĞƉƌŝǀĂƟŽŶͲ ǁŽƵůĚ ŶŽƚ ŝŶŇƵĞŶĐĞ ƚŚĞ ŽƵƚĐŽŵĞƐ dŚĞ ĞǆƉĞƌŝŵĞŶƚ ĂůƐŽ ĐŽƌƌĞĐƚ ĞĚ ĨŽƌ ƚŚĞ ƉŽƐƐŝďŝůŝƚǇ ƚŚĂƚ ĂŶǇ ĐŽŐŶŝƟǀĞ ŝŵ ƉĂŝƌŵĞŶƚ ƐŚŽǁŶ ďǇ ĐƐƚĂƐǇ ƵƐĞƌƐ ŵŝŐŚƚ ŚĂǀĞ ďĞĞŶ ŝŶ ƉůĂĐĞ ďĞĨŽƌĞ ƚŚĞǇ ƐƚĂƌƚĞĚ ƵƐŝŶŐ ƚŚĞ drug. EŽƚ ĞǀĞƌǇŽŶĞ ǁĂƐ ĐŽŶǀŝŶĐĞĚ ZĞ ĐĞŶƚůǇ ƚŚĞ h< EĂƟŽŶĂů ,ĞĂůƚŚ ^ĞƌǀŝĐĞ ;E,^ Ϳ ƉƵďůŝƐŚĞĚ ĂŶ ĂƌƟĐůĞ ŝŶ ƌĞƐƉŽŶƐĞ ƚŽ ,ĂůƉ ĞƌŶƐ ƐƚƵĚǇ ĐůĂŝŵŝŶŐ ƚŚĂƚ ǁŝƚŚŽƵƚ ĨƵƌƚŚĞƌ ƌĞƐĞĂƌĐŚ ŝƚ ŝƐ ŶŽƚ ƉŽƐƐŝďůĞ ƚŽ ƐĂǇ ƚŚĂƚ ƚŚĞƌĞ ŝƐ ŶŽ ĞǀŝĚĞŶĐĞ ƚŚĂƚ ĞĐƐƚĂƐǇ ĐĂƵƐĞƐ ďƌĂŝŶ ĚĂŵĂŐĞŶ ŝŶĐŽƌƌĞĐƚ ĂƐƐĞƌƟŽŶ ĂĐĐŽƌĚŝŶŐ ƚŽ ,ĂůƉĞƌŶ tŚĂƚ ŝƐ ĐƌŝƟĐĂů ƚŽ ƵŶĚĞƌƐƚĂŶĚ ŚĞƌĞ ŝƐ ƚŚĂƚ ǁĞ ĚŽŶƚ ŚĂǀĞ ƚŚĞƐĞ ƐŽƌƚƐ ŽĨ ĚĞďĂƚĞƐ Neurology So MDMA can be helpful in trauma therapy, but what about its long term neurological effects? Does it really turn your brain into Swiss cheese, as is often claimed by worried parents? Or cause Parkinson’s disease? Recent evidence suggests the opposite. ϭϲ

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XTC Neurology