Upload
chamika-huruggamuwa
View
218
Download
0
Embed Size (px)
Citation preview
7/29/2019 Wound Healing-ms 1
1/20
WOUND HEALINGMS-1
7/29/2019 Wound Healing-ms 1
2/20
Regeneration
Repair
Restitution
7/29/2019 Wound Healing-ms 1
3/20
Cells Labile
StablePermanent
7/29/2019 Wound Healing-ms 1
4/20
Granulation Tissue
7/29/2019 Wound Healing-ms 1
5/20
Angioneogenesis/Neovascularization
Migration and proliferation of fibroblasts
Deposition of ECM
Remodelling
7/29/2019 Wound Healing-ms 1
6/20
Components of the ECM
7/29/2019 Wound Healing-ms 1
7/20
As BM and Interstitial matrix
Collagen,Elastin
Fibronectin,Laminin Proteoglycan,hyaluronan
7/29/2019 Wound Healing-ms 1
8/20
Molecular events in cell growth
7/29/2019 Wound Healing-ms 1
9/20
Intercellular signalling-
auto/para/endocrine
Cell surface receptors
Signal transduction system
Cell transcription
7/29/2019 Wound Healing-ms 1
10/20
Growth Factors
7/29/2019 Wound Healing-ms 1
11/20
TGF EGF PDGF
7/29/2019 Wound Healing-ms 1
12/20
Cyclins and Chalones
7/29/2019 Wound Healing-ms 1
13/20
Contact inhibition
7/29/2019 Wound Healing-ms 1
14/20
Reduction in material
Reduced GF
Increased inhibitors
7/29/2019 Wound Healing-ms 1
15/20
HEALING BY -
First intention
Second intention
7/29/2019 Wound Healing-ms 1
16/20
Wound contraction vs contracture
7/29/2019 Wound Healing-ms 1
17/20
Factors affecting wound healing
Favourably
Adversely
7/29/2019 Wound Healing-ms 1
18/20
Complications of healing in
Skin Intestine Brain
Urinary tract Liver Bone
Myocardium Lung Kidney
7/29/2019 Wound Healing-ms 1
19/20
Wound strength
Wound failure
7/29/2019 Wound Healing-ms 1
20/20
FRACTURE HEALING-
Process
Factors affecting
Complications