Welcome toArizona State University

World Vista MeetingWorld Vista MeetingJanuary, 2009January, 2009

ASU• 67,082 Students

• 53,298 Undergraduates• 13,784 Graduate Students

• Over 12,000 Employees• About 3,000 Faculty Members• 4 Campuses in the Phoenix area (Tempe,

West, Downtown, Polytechnic)

Department of Biomedical Informatics

Arizona Biomedical Collaborative 1

Brickyard on Mill Ave

Department ofBasic Medical

Sciences

Phoenix Biomedical Campus Tempe

Ira A. Fulton School of Engineering

Department of

Biomedical Informatics

Department ofComputer Sci.

& Eng.

InterdisciplinaryInformatics

Progs.

Arizona Board of Regents

College of Medicine-Phoenixin partnership with Arizona

State University

Arizona State University

EngineeringDepartment

s

EngineeringDepartment

s

EngineeringDepartment

s

EngineeringDepartments

School of Nursing& Health Innovation

Engineering

Departments

Engineering

Departments

OtherSchools

University ofArizona

School of Computing& Informatics

BioinformaticsClinical

InformaticsPublic Health Informatics

BMI Research FociImaging

Informatics

CAVITARY MASSFinding: massMass ID: 1Margins: spiculatedLength: 2.3cmWidth: 1.2cmCavitary: YCalcified: NSpatial relationships: Abuts pleural surface; invades aorta

Capture data once, use it many times

Cognition and Decision Making

Data Mining/Predictive Modeling

NLP/AI/Structured Knowledge Representation

Embedded Systems

Collaboration Technologies & Methods

FacultyRobert A. Greenes, M.D., Ph.D.Ira A. Fulton ChairMember, Inst of Med, Nat Acad Sci(from Harvard University)

Vimla Patel, Ph.D., D.Sc.Vice ChairMember, Nat Acad Soc Sci (Canada)(from Columbia University and joint with UA)

William G. Johnson, Ph.D. Director, Center for Health Information and Research(from ASU)

Edward H. Shortliffe, M.D., Ph.D.ProfessorMember, Inst of Med, Nat Acad Sci(from Columbia University)

Trevor Cohen, M.D., Ph.D. Assistant Professor(from Columbia University)

Valentin Dinu, Ph.D.Assistant Professor(from Yale University)

Kanav Kahol, Ph.D.Assistant Professor(from ASU and joint with Banner Health)

Douglas Fridsma, M.D., Ph.D. Associate Professor(from Univ. of Pittsburgh and joint with Mayo)

Diana Petitti, M.D., M.P.H. Professor (from Kaiser Southern California)

Jianming Liang, Ph.D. (arriving)Associate Professor (from Siemens Corp.)

Graciela Gonzalez, Ph.D.Assistant Professor(from ASU, pending, now Asst Res. Prof)

Clinical and Research FacultyHoward Silverman, M.D., M.S.The University of Arizona College of Medicine – Phoenix(joint with ASU)

10 Collaborating faculty in SCI11 Affiliate Faculty from various other disciplines at ASU12 Adjunct Faculty from diverse organizations around valley

Craig Parker, M.D., M.S. Associate Research Professor(from Intermountain Healthcare in Utah)

Wade Bannister, Ph.D. Assistant Research Professor(from ASU)

Jose Piovanetti-Perez, M.D. Associate Research Professor(from Universidad Central del Caribe, P.R.)

Affiliate and Adjunct Faculty

BMI Partners & Collaborators

Life Sciences

Nursing Law &Bioethics

Psychology

Computer Science

& Engineering

BioengineeringPublic Health& Business

Mathematics& Biostatistics

Growth of the Department• 5 year target

– Establish expertise in all 4 key foci• Initially through high profile recruits

– Core faculty ~ 24 FTE (30-35 people)– Clinical & research faculty ~ 10-15 FTE– Total w/ affiliates 60-70

Current year targets• Senior faculty leader for bioinformatics

& personalized medicine• Midlevel-senior faculty for data mining

& predictive modeling• Junior-midlevel natural language

processing & clinical knowledge representation

Education and Training Programs

2007– 13 students admitted into the first MS BMI class

• From diverse disciplines– Medicine, Computer Science, BioEngineering, Psychology, Nursing,

Biology, and Mathematics– Medical school informatics curriculum co-taught with physicians and basic

medical scientists2008

– 7 students admitted into the first PhD BMI class – 7 students admitted into the second MS BMI class in Fall 2008

2009– Proposal for BS degree program approved by Curriculum and Academic

Programs Committee (CAPC), awaiting Academic Senate approval

Research foci• Major emphasis on statewide, regional and

community initiatives– HRAA – Health Research Alliance Arizona

• the Arizona statewide CTSA initiative (proposal stage)– HIE – Health Information Exchange

• Working with Arizona Health Care Cost Containment System (AHCCCS) – state Medicaid agency

• Aso with Arizona Health-e Connection (AzHeC) – consortium for EHR, ERx, HIE interoperability

– Morningside Initiative• Consortium to develop clinical decision support repository,

methods, and organizational framework for sharing– CHIR – Center for Health Information and Research

• Health services research unit with statewide claims database – Arizona HealthQuery

Health Research Alliance Arizona• Unique approach to CTSA – statewide consortium

– Proposal in preparation• BMI coordination role

– Initial work via TRIF funding• Have begun work on

portal– Customization– Discovery tools– Content management– Collaboration tools– Portlets for access– Social networking/Web 2.0 features

Research activities

The Morningside Initiative • A consortium of

DOD, VA, Kaiser, Partners, Henry Ford Hospital, Intermountain Health, ASU in coordinating role

• For knowledge sharing for clinical decision support (CDS)

• Initial focus on diabetes

• Startup support from TATRC

• Goal of scaling up as national-level public-private initiative

Enterprise Knowledge

Base

Alerts Order setsGuidelines Reminders

Shared Knowledge

Base

Enterprise Knowledge

Base

Enterprise Knowledge

Base

…

Collaborative Knowledge Management

Interoperable health records and CDS– Interagency Service Agreement with AHCCCS (state

Medicaid agency)– for joint activities in EMR and health information exchange

(HIE) development– application of CDS

- Gateways

RLS

DHS ImagingHealth Plans AHCCCSLabs

Provider EMRs Hospitals Pharms/PBMs

Clinics

The InternetHIE Data

RHIOs/HIEs

RLS - Record Locator Service (record

matching)

State-wide HIE, CDR, & CDS Infrastructure

• Collaboration with Arizona’s state Medicaid agency (AHCCCS), Arizona Health-e Connection, and other institutions

• Funding through two Medicaid Transformation Grants

• Working to build consensus and define architectures for methods of delivering better quality and more efficient healthcare – to Arizona’s Medicaid beneficiaries – but in a manner that can be expanded state-wide

Center for Health Information and Research*

•Community Health Information Systems•Health Care Effectiveness•Health Care Disparities•Surveillance Systems•Environmental Effects on Health •Patient Safety•Health Care Workforce•Economic Evaluations of Health Care

* CHIR and director, William Johnson, received 2008 President’s Gold Medal for Social Embeddedness

Arizona HealthQuery – a unique statewide database of 9 million patients

Simulation and training• Study of surgical errors

and fatigue– Best paper award, Amer.

Coll. of Surg. annual meeting

• Use of Wii as warmup for surgery– Best paper award, MMVR,

news coverage channel 5, BBC, Wall St J blog

Other research• Knowledge-guided genome data analyses

– Guiding GWAS studies, with TGen– Selection of therapeutic targets, with Tgen

• Next-generation sequencing, TGen, collaboration with BMI– Algorithm and pipeline optimization development

• Personalized biomarkers– Partnership for Personalized Medicine, with BMI

• Alzheimer disease early detection based on haptic memory changes, with Mayo

• Clinical trials infrastructure modeling framework, with Mayo and CTSA

Successes• Over $9M in funding in our first year• 2 graduate degrees and unique med school curriculum

launched, and unique undergraduate curriculum proposed

• Stellar faculty recruited from Columbia, Yale, Harvard, Pittsburgh, Utah, Kaiser, and elsewhere

• Developed collaborations with UA, TGen, several ASU Depts/Schools, Mayo, Banner, BNI, VA, MIHS, AHCCCS

• Awards and recognition received by faculty– Patel - SCI 2008 Service Faculty of the Year– Johnson – 2008 ASU President’s Gold Medal– Greenes – 2008 ACMI Morris F. Collen award– Kanav et al - press coverage for surgical simulation studies and

MMVR best paper award– Shortliffe - named President & CEO of American Medical

Informatics Association

Progress report• See:

http://bmi.asu.edu/ downloads/IMIA Yearbook08_preprint.pdf