Upload
novasuryati
View
219
Download
0
Tags:
Embed Size (px)
DESCRIPTION
Welcome Lecture
Citation preview
WELCOME LECTURE
dr. Rizki Rahmadian
“ mimpi adalah kunci untuk kita menaklukan dunia, berlarilah tanpa lelah sampai engkau
meraihnya”
nidji
Limb Salvage Surgery for Extremity Bone Sarcoma
Amputation
Introduction
• Concept of limb salvage surgery 25 years
• 1970s adriamicyn & MTX
• Ralp Marcove, Kenneth Francis & Hugh Watts limb salvage surgery technique
Introduction
Today 90-95 % patient with extremity sarcoma who are treated at major centers specializing in
musculoskeletal oncology can undergo limb-sparing surgery procedures
Introduction
This dramatic alteration :
1. Improved understanding of tumor biology;
2. Effective induction chemotherapy;
3. Technical advances in surgical techniques;
4. Better characterization of the biomechanics of the human
skeleton;
5. Advanced material engineering and manufacturing
techniques;
6. The development of a reliable, stable modular prosthesis
for reconstruction of the hip, shoulder, and knee.
Early Management & Referral
• A successful limb salvage depends on :– A well - coordinated and timely series the
first physician to see the patient
– History and general examination
– The basic work-up should include high quality plain radiographs for bone lesions.
Early Management & Referral
Biopsy is not a part of the initial management of these lesions and is usually the last step in the
work-up.
The biopsy should be performed by the surgeon who will be doing the definitive
surgery.
Work-up
• Multidisciplinary team : – Orthopedic oncologist– Medical oncologist– Radiation oncologists– Musculoskeletal radiologist– Pathologist– Clinical psychologist– Social worker
CLINICO PATHOLOGICAL CONFRENCE
Staging
• The basic staging work : – High quality plain radiographs– Magnetic resonance imaging
study of the entire tumor and nearby anatomic structures
– Computed tomography scan of the chest
– Whole body technetium bone scan– Biopsy of the tumor
Work-up
The biopsy site must be carefully planned and located along so-called
“limb—salvage lines”
Biopsy
Drain Placement
Staging
Patient Education
The patient and the patient’s family should be given the opportunity to
participate in the decision
Indication
• Every patient with a malignant tumor of the extremity should be considered for limb salvage.
• The patient’s prognosis has a limited impact on the decision to perform limb salvage surgery.
• In selected cases, limb salvage can be combined with metastasectomy.
Indication
• Minimum morbidity and rapid return to function.
• Patients can enjoy relief from pain, improved quality of life, and intact body image that limb salvage can offer, even if they may not survive long-term.
Barriers
Barriers to limb salvage include – Poorly placed biopsy incisions, – Major vascular involvement, – Incasement of a major motor nerve,– Pathological fracture of the involved bone,
and others.
These adverse factors should not be viewed as absolute contraindications.
STAGES OF LIMB-SPARING SURGERY
Limb-sparing procedure can be divided into five stages :
• Neoadjuvant chemtherapy• Tumor resection must spare significant
structures.• Stable, painless skeletal reconstruction• The surrounding and supporting soft tissue• Adjuvant chemotherapy
Huvos Tumor Necrosis Grading System
Surgical Resections and Reconstructions
• The cornerstone of a limb salvage procedure is a complete resection of the tumor with an adequate margin.
• Margins can be defined as intralesional, marginal, wide, and radical
Surgical Resections and Reconstructions
• After completion of the tumor resection, the surgeon must reconstruct the resulting surgical defect.
• The excised segment of bone must be replaced– Large internal prosthesis, – Segment of allograft bone, – Composite of an allograft and a prosthesis– Other methods.
Resection Arthrodesis
Resection Arthrodesis
Osteoarticular Allograft
Endoprosthesis
Endoprosthesis
Expandeble endoprosthesis
Case
• Survival : 5 yaers survival rate 40 -70 %, local recurrence : 5 -10 %
• Immidiatete and Delayed Morbidity : increase revision
• Function : better than amputation
• Psycosocial Benefits : gooad early psycosocial adjustment
Thank you