Welcome

Education, Science and Medical

Relationships

October 21, 2013

Meeting Topics

• Introductions• Itinerary for the Day• CWRU School of Medicine Background and Vision• Science Without Borders Program • Goals for CAPES MOU and education discussion• Discussion and Q&A

Overview of CWRU School of Medicine

Christopher D. Masotti, CPA, MBA

Vice Dean for Finance and Administration

School of Medicine Quick Facts

Full-Time FacultyMD StudentsPhD StudentsMaster StudentsEmployeesRevenue as % of CWRU Total

2,400850360350

1,96046%

Sources of Funds

74%

11%

5%

11%

FY11

68%

14%

6%

12%

FY14

65%

18%

5%

11%

FY19 (anticipated)

Total Revenue: $464MTuition Revenue: $52M

Total Revenue: $460MTuition Revenue: $65M

Total Revenue: $515MTuition Revenue: $95M

FY13 Sources of Research Funding

Federal

State/local govt, foundations, industry

9%

91%

School of Medicine Affiliations•University Hospitals Case Medical Center Primary affiliate; full-time faculty; clinical FTE employed University Hospitals Medical Group, research SOM

•MetroHealth Medical Center Major affiliate; full-time faculty employed by MetroHealth

•Cleveland Clinic Foundation—Cleveland Clinic Lerner College of Medicine Full-time faculty employed by Cleveland Clinic Foundation

•Louis Stokes Veterans Affairs Medical Center Full-time faculty employed by Veterans Affairs Medical Center

• Ranked in U.S. News & World Report Honor Roll

• 1 of only 5 cities with more than one hospital on the Honor Roll

• A top healthcare destination

• Only three universities in the country with multiple affiliated hospitals in the top rankings

• Case Western Reserve University• Harvard University• University of California—Los Angeles

Cleveland as Healthcare Destination

Overarching Goals of SOM1. Leadership in medical and graduate

education2. Innovative and strategic research

environment3. Meaningful community engagement and

partnerships4. Enhanced institutional climate

http://casemed.case.edu/ora/strategicplan.cfm

From Discoveries to Cures

Medical Education

Overview

Clint W. Snyder, PhDInterim Vice Dean for Education and

Academic Affairs

Attracting and training the best students

We enroll some of the nation’s top studentsMedical College Admission Test (MCAT)Ranked 12th in the country in MCATS in 2012; ranked 8th in 2011

And they become even better while they’re hereNational Medical Licensing ExaminationU.S. Avg: 221Case Western Reserve: 231

School of Medicine Education• Primary educational program is at CWRU

School of Medicine (WR2 Curriculum)– 165 students per year

• CWRU Cleveland Clinic Lerner College has a separate track (CCLCM)– 32 students per year

Western Reserve2 (WR2) Curriculum

Research and Scholarship MD Thesis

1st Year 2nd Year 3rd Year 4th Year

Basic Sciencesand

Early Clinical Training

Core Clerkships

Basic Science Integration

Electives and Board Study

USMLE Step 1

Acting Internships

Transition to Residency

Advanced Electives

USMLE Step 2(CK/CS)

Research and Scholarship MD Thesis

Foundations of Medicine and Health

Advanced Clinical Experiences and Residency Preparation

CCLCM Curriculum Overview Years 1-5

Match Day 2013Of our school’s 191 matches, 20 percent matched to top-ten hospitals as ranked by U.S. News & World Report

• Cleveland Clinic• Duke• Johns Hopkins• Massachusetts General• UCLA

39 will stay in Cleveland: • University Hospitals Case

Medical Center• Cleveland Clinic• MetroHealth Medical Center

Medical Education Opportunities

Clinical Electives: •Sydney Medical School (Australia)•Nanjing U Hospital Internal Medicine (China)•Zhejiang U (China)•FEDEPO Santa Domingo (Dominican Republic)•Pop-Wu Medical Clinic (Guatemala)•New OB/GYN residency (Guyana) •Internal medicine Al-Gandhi Hospital; Hyderabad (India)•Saitama Medical U at Saitama Medical Center (Japan)•U of Tokyo (Japan)•Maseno U School of Medicine (Kenya)•Instituto Nacional de Enfermedades Respiratorias (Mexico)•Lamay (Peru)•Jagellonian U (Poland)•U of Puerto Rico (Puerto Rico)•Baragwanath Hospital; Johannesburg (South Africa)•Khon Khaen U (Thailand)•St. Mary’s Hospital (Uganda)

Bioethics•The Netherlands•Costa Rica•France•Spain•India

Fogarty-Global Health mentored experience (red stars) in Papua New Guinea/Dominican Republic/Uganda/Brazil

Inside the New Medical Education Building

• Expanded medical education programs

• New joint programs• Expanded Community

Health initiatives• Separate identities and

curricula, but will share sim center, anatomy lab, food service, etc.

Medical Education BuildingCurriculum Goals

• Future approaches to medical education• Practical sharing between CCLCM and the University

Program• Encouraging inter-professional education• Multiple educational resources• Pathways: Urban Health, World Medicine, Medical

Humanities, Business of Medicine

Campaign: Impact the Care and Health of the Community• $25 million to establish the

Weatherhead Institute for Family Medicine and Community Health

• Vision: to promote health and

integrate care for the whole person and community through research, education, leadership and advocacy.

Vision Topic – World Medicine

The World is ShrinkingDiseases arise abroad and sweep the U.S.

AIDSDrug resistant TBSARS

Conversely, our scourges are exportedMetabolic syndromeSome cancers

Vision Topic – World Medicine

– Approaches to health care differ abroad– Strategies for delivering care in under-

resourced countries might inform urban and rural health here

– Developed countries public health and health care may inform new models for the U.S.

– Our students may benefit from wealth of clinical experience abroad

Graduate Education

Overview

Paul MacDonald, PhDAssociate Dean for Graduate Education

SOM Graduate Education Office

Paul MacDonaldMartin SnyderRobert PetersenMonica MontanoGeorge Dubyak

Diana Ramirez-BergeronJoseph WilliamsDeborah NoureddineMalana BeyDan Korgan

Seeds of DiscoveryThe Ph.D. White Lab Coat Ceremony

76 students entering 11 different programs57 % female, 43 % male11 different countries (33 %)36 % from Ohio, 11 % from CWRU

Guiding Principles for Graduate Educationpreparing students for success as future leaders in the rapidly

changing biomedical research environment of the 21st century.

• Interdisciplinary and collaborative

• Concept-driven and self-directed study

• Professionalism and life-long learning

• Faculty and students as colleagues

Biochemistry Tracks: RNA Biology Structural Biology & BiophysicsBioethicsBiomedical EngineeringCell BiologyEpidemiology and BiostatisticsGenetics Tracks: Developmental BiologyMolecular Biology and MicrobiologyMolecular MedicineMolecular Virology

Neurosciences Tracks: Developmental BiologyNutritionPathology Tracks: Cancer Biology

Exp. PathologyImmunology Mol. Cell. Basis of Disease

Pharmacology Tracks: Cancer Therapeutics,

Molecular Pharmacology, Membrane Structural Biology,Translational Therapeutics

Physiology and BiophysicsSystems Biology & Bioinformatics

Ph.D. Graduate Programs at CWRU

1. Biomedical Sciences Training Program – BSTP

2. Medical Scientist Training Program – MSTP

Dual-degree – M.D./Ph.D.

3. Direct Admission to programs

SOM Ph.D. Entry Routes

Students enter together, then earn a PhD in one program

First semester: cell & molecularbiology

Lab rotations with prospective advisors

PhD: Biomedical Sciences Training Program

Over 200 faculty advisors

Smaller labs with individual attention

PhD: Biomedical Sciences Training Program

CWRU MSTP

NIH funded Medical Scientist Training Program, 19562 years medical school + 4 years PhD + 2 years clerkshipsAccept about a dozen students/year

90 current students and 194 graduatesAMCAS Application opens in June

Time to Degree (TTD) and Publications

Average TTD (years)

Average number of publications/program

Number of publications/grad

Average primary publications/program

Primary publications/grad

5.7

103.1

3.8

47.9

1.7

5.5

109.4

3.1

54.7

1.5

2002-2007 2008-2013

DiversificationEducational Programs

Expanded Programs• Masters of Science in

Anesthesiology• Masters of Science in

Medical Physiology• Masters in Biostatistics

Upcoming Programs• Physician Assistant (2016)• Masters in Informatics• Masters of Science in

Medical Education

Research Overview and

Strategy

Christopher D. Masotti, CPA, MBA

Vice Dean for Finance and Administration

Translating Research from Discoveries to Cures• School and its affiliated hospitals

attract $569 million in research funds annually

• No. 17 in the nation in NIH research grants awarded to medical schools

• No. 1 in Ohio—more in NIH grants to CWRU SOM than any other medical school in Ohio

Research Abroad - Institutions

•Imperial College (UK)•Institute Pasteur (France & Madagascar)•Medical Microbiology & Parasitology, University Hospital (Germany)•Max Planck Institute •Walter and Eliza Hall Institute, U Queensland, (Australia)•James Cook U, ICGEB (Delhi, India)•Washington U (St. Louis)•Notre Dame U (South Bend)•Zhabei Health District (Shanghai)

From Discoveries to Cures

Research Areas

MalariaFilariasisVector EcologyHIVTBSchistosomiasisLymphatic FilariasisRift Valley FeverOnchocerciasisDengue FeverGeneticsBioethicsCommunity Assessment

Collaboration . . .is the order of the day

• Research centers and cores – CTSC, Cancer, AIDS, Proteomics, Imaging,

Regenerative Medicine

• Institute for Computational Biology– Case Western Reserve University– University Hospitals Case Medical Center– Cleveland Clinic Foundation

CWRU to receive nearly $2 million from state to lead the Ohio Clinical Trials Collaborative

Statewide clinical-trials platform• Patients: quicker access to innovative treatments• Ohio: gain edge in attracting clinical studies

Collaboration among:• Case Western Reserve University (lead)• Ohio State University • University of Cincinnati

Economic Engine for Ohio

TranslationMarketingDrug Discovery Activities

Consulting with over 50 faculty investigators

5 programs fundedCAHH

25 programs fundedHTS

6 programs fundedCTSC

4 research incentive awardsTTO

Totaling over $4M in new

investments

Gary Landreth

Kevin Cooper

Mark Chance

Hyoung-Gon Lee

Clark DistelhorstJerry SilverSusann Brady-KalnayDavid Katz

Push Program30+ programs

marketed at regular bi-annual meetings

Commercialization

Key Focus Areas Driving Key Clinical Programs

SOM Investment Blueprint

• Invest in areas of interdisciplinary strength: Cancer, Infection/Inflammation, Imaging/Structural Biology, Visual Sciences, Cardiovascular

• Invest in emerging areas: Informatics, Translational Neuroscience, Population and Community Health, Genome Sciences

• Invest in high risk/high return areas: Therapeutics, Commercialization, Metabolic Sciences

Professor Jorge Almeida GuimarãesPresident of CAPES

Science Without Borders Program

Goals for CAPES MOU and

Education Discussion