Molecular Pharmaceuticsincluding an emphasis onPharmacoengineering

pharmacy.unc.edu/moph/phd-programDivision of Molecular Pharmaceutics

Admissions

Admission is competitive. Over the last five years, GRE scores for those accepted average in the eighty-fifth and eighty-eighth percentiles for the verbal and quantitative sections, respectively.

Teaching and research assistantships provide an annual stipend of $27,500 plus in-state tuition and health-insurance coverage.

Qualified applicants will also receive the Molecular Pharmaceutics Scholar Fellowship, which provides a $3,000 supplement to the first-year stipend and may be extended to the second year.

Admissions information at go.unc.edu/pharmdoc

Contact

Philip Smith, PhD Division Director of Graduate Studies pcs@email.unc.edu 919-962-0095

Facilities

• MOPH faculty and students work in 22,000 square feet of lab space, most of it newly constructed or renovated since 2008.

• Genetic Medicine Building: Completed in 2008 and shared with the UNC School of Medicine, the GMB contains 75,000 square feet of the School’s lab space.

• Image Research Building: Scheduled to open in 2014 across the street from the GMB, the IRB will add an additional 75,000 square feet of lab space to the UNC Eshelman School of Pharmacy, bring-ing the total to approximately 225,000 square feet.

• Carolina offers outstanding shared instruments and state-of-the-art core facilities.

Director, Biomedical Research Imaging Center

Dixie Lee Boney Soo Distinguished Professor of Neurological Medicine

Non-invasive multi-modality imaging for guiding and monitoring therapeutic interventions.

pharmacy.unc.edu/ weililin

Weili Lin

John A. McNeill Distinguished Professor

Vice Dean

Nanoparticles and other novel drug delivery technologies to treat or prevent cancer and infectious diseases

pharmacy.unc.edu/ russellmumper

Russell Mumper

Associate Professor

Division Director of Graduate

Admission and Graduate Studies

Division Vice Chair

Pharmacokinetics and drug metabolism, primarily glucuronidation. Study of quantitative proteomic LC-MS methods of proteins involved in drug disposition

pharmacy.unc.edu/ philipsmith

Philip SmithAssistant Professor

Infectious diseases; drug delivery to and imaging of metastatic tumors

pharmacy.unc.edu/ samlai

Sam Lai

Assistant Professor of Radiation Oncology

Development and application of nanoparticle therapeutics in cancer treatment; develop-ment of 3D in vitro tumor models of cancer metastasis that reflects organ specificity

nccancerhospital.org/members/andrew-wang

Andrew Wang

Fred Eshelman Distinguished Professor

Molecular medicine, specifically gene delivery and therapy for various genetic and acquired diseases

pharmacy.unc.edu/ xiaoxiao

Xiao Xiao

Pharmacoengineering

In collaboration with the UNC-NCSU Joint Depart-ment of Biomedical Engineering, MOPH offers the PhD program in pharmaceutical sciences with an em-phasis on pharmacoengineering, which integrates en-gineering methods with pharmaceutical sciences.

pharmacy.unc.edu/pharmacoengineering

Center for Nanotechnology in Drug Delivery

MOPH is home to the Center for Nanotechnology in Drug Delivery directed by Mescal S. Ferguson Distin-guished Professor Alexander “Sasha” Kabanov, PhD. The center focuses on improving human health by safely and effectively translating new drug and imag-

ing discoveries into clinical trials using nanotechnol-ogy. The center creates and develops cutting-edge, nanotechnology-based drug- and imaging-delivery systems; facilitates drug discovery and identification of drug leads; and formulates and characterizes the identified preclinical and clinical leads for testing.

pharmacy.unc.edu/cndd

Molecular Pharmaceutics at Carolina

Molecular pharmaceutics deals with delivering and maintaining the desired amount of a thera-peutic agent at a target site for a specific period of time. This discipline is crucial to turning new molecular entities into safe and effective drugs.

Our Faculty Sets Us ApartThe MOPH faculty includes developers of a number of novel, patented drug-delivery systems; NIH study section members; entrepreneurs; editorial board members; and authors of hundreds of scholarly works. Our faculty is highly collaborative and entrepreneurial, having applied for eighteen patents based on their research and establishing seven new pharmaceutical and biotech companies in recent years.

The faculty comprises eleven tenure-track faculty and ten research faculty. Our tenure-track faculty members have averaged more than $800,000 each in annual research funding over the last four years.

Fred Eshelman Distinguished Professor

Division Chair

Solving problems in nuclear imaging and therapy and in the development of novel formulations and drug delivery systems

pharmacy.unc.edu/ michaeljay

Michael Jay

Debreczeny Distinguished Professor

Professor and Chair, UNC/NCSU Joint Department of Biomedical Engineering

Director, Curriculum of Applied Science and Engineering

Signaling in single cells, microfabricated systems for cellular analysis

chem.unc.edu/ people/faculty/ allbritton

Nancy Allbritton

Associate Professor

Living cells as drug delivery vehicles for treatment of neurodegenerative disorders

pharmacy.unc.edu/ elenabatrakova

Elena Batrakova

Professor, UNC/NCSU Joint Department of Biomedical Engineering

Associate Director for Education, UNC Biomedical Research Imaging Center

Developing new technologies for imaging blood flow, microvasculature and molecular markers using ultrasound and microbubble contrast agents

pharmacy.unc.edu/ pauldayton

Paul Dayton

Director, Frank Hawkins Kenan Institute of Private Enterprise

Chancellor’s Eminent Professor of Chemistry, UNC

William R. Kenan, Jr. Distinguished Professor of Chemical Engineering, NCSU

New medicines and vaccines; nanomedi-cine; medical devices; entrepreneurship

pharmacy.unc.edu/ josephdesimone

Joseph DeSimone

Assistant Professor

Integrating biomaterials design, biomolecular engineering and micro/nanofabrication toward on-demand drug delivery focused on cancer, diabetes, and regenerative medicine

www.bme.unc.edu/labs/gulab

Zhen Gu

Fred Eshelman Distinguished Professor

Development of non-viral vectors for gene (including oligonucleotides) therapy; recep-tor mediated drug and vaccine targeting using self-assembled nanoparticles

pharmacy.unc.edu/ leafhuang

Leaf Huang

Boshamer Distinguished Professor

Regulation of signal transduction and cell growth by integrin-mediated cell adhesion, therapeutic drug design and delivery

pharmacy.unc.edu/ rudyjuliano

Rudy Juliano

Mescal S. Ferguson Distinguished Professor

Director, Center for Nanotechnology in Drug Delivery

Enabling technologies using polymers, magnets, small drugs and biotherapeutics to treat cancer, brain and other diseases

pharmacy.unc.edu/ alexanderkabanov

Alexander Kabanov

Associate Professor

Application of radioactivity and radioactive drugs to solve clinical research problems

pharmacy.unc.edu/ richardkowalsky

Richard Kowalsky

Assistant Professor

Harnessing the power of stem cells and molecular imaging to develop and translate innovative cancer therapies

pharmacy.unc.edu/ shawnhingtgen

Shawn Hingtgen