Grade 12 University Biology

Cellular Respiration: GlycolysisSUMMARIZED OVERVIEW

Key Types of Reactions:

Substrate level phosphorylation: ____________________________________________________________

____________________________________________________________

Oxidative decarboxylation: ___________________________________________________________________

___________________________________________________________________

Oxidative phosphorylation: ___________________________________________________________________

___________________________________________________________________

WHAT IS CELLULAR RESPIRATION?Cellular respiration is a biochemical pathway used to produce ATP from GlucoseWrite the general formula for cellular respiration?

Notice that ATP is not a direct product of this process. ATP will be made indirectly via coupled reactions and by using some released energy to create a proton gradient in the mitochondria to power ATP synthase.

GLYCOLYSIS

Glycolysis is the first phase of the process of cellular respiration. Once glucose enters a cell, the process of

glycolysis begins immediately in the ____________________________ where enzymes are waiting.

Grade 12 University Biology

GLYCOLYSIS I – the Investment phaseWhy is glycolysis I called the investment phase?

_____________________________________________________________________________________________

_____________________________________________________________________________________________

In glycolysis (I) glucose is activated by the addition of phosphate groups from ATP in an enzyme mediate process

called ________________________________________________________

GLYCOLYSIS II – the Pay-off phaseWhy is glycolysis II called the pay-off phase?

_____________________________________________________________________________________________

_____________________________________________________________________________________________

By the end of glycolysis II, glucose has been broken down from _____ carbons to a ____ carbon compound called

_________________________ (also known as ______________________________ ).

*see glycolysis diagram for details of the process, names of intermediates, and types of reactions at each step

THE END RESULT .

In order to keep track of how glucose is modified and rearranged during glycolysis we number each carbon

Summing up glycolysis

Net gain:

What has happened to Glucose?

Grade 12 University Biology

Write the overall reaction for glycolysis:

• In the cytosol, for each glucose molecule consumed, only 2 ATP were produced

• This means that ________ more ATP are made in the mitochondria! Wowza!

Draw a labelled diagram of the mitochondria in the space below

Pyruvate Oxidation:

Grade 12 University Biology

The Krebs Cycle:

Grade 12 University Biology

Grade 12 University Biology

The Krebs Cycle:

Grade 12 University Biology