Human Immunology Volume 15, Number 1, January 1986

Contents

HIROO MAEDA, RANKO HIRATA, ALLAN THOMPSON, and RYOZABURO MUKAI

Molecular Characterization of Three HLA Class lI Molecules on DR4 and DRw9 Halplotypes" Serological and Structural Relationships at the Polypeptide Level

JOHN KARLOF and NANCY MENDELL An Evaluation of Typing Procedures for Quantitative Data: Results of a Monte Carlo Study

.JEFFREY A. LEDBE'ITER and EDWARD A. CLARK Surface Phenotype and Function of Tonsillar Germinal Center and Mantle Zone B Cell Subsets

P. PARHAM, P. ANTONELLI, L. A. HERZENBERG, T.J. KIPPS, A. FULLER, and F. E. WARD

Further Studies on the Epitopes of HLA-B7 Defined by Murine Monoclonal Antibodies

DAVID D. ECKELS (CHAIRMAN) and ADRIANNA ZEEVI (CO-CHAIRMAN) ASHI Workshop Summary Repor t of the Science and Education Subcommittee: Structural and Functional Relationships of Human Class II M H C Molecules

DVORA KATZ, DANIEL SUEZ, CHAIM BRAUTBAR, TIRZA COHEN, ZVI BENTWICH, and EDNA MOZES

Genetic Control of HLA-Linked Immune Responsiveness to ( H , G ) - A - L

GLENN F. PIERCE, STEPHEN H. POLMAR, BERNICE Z. SCHACTER, CHARLOTTE BROVALL, DAVID L. HORNICK, and RICARDO U. SORENSEN

Natural Cytotoxicity in Immunodeficiency Diseases: Preservation of Natural Killer Activity and the In Vivo Appearance of Radioresistant Killing

NOBUO OKUMURA, FUMIE AOSAI, KATSUYUKI YUI, KEIZO YAMASHITA, KOJI YABU, MASAMlTSU KANAI, and AKIHIKO YANO

Cellular FITC-Linked Immunospecific Assay (CelI-FLISA) For Detect ion of Monoclonal Antibodies Against Cell-Surface Antigens

MARIA PIA PISTILLO, ULRICH H)~MMERLING, BO DUPONT, and GIOVAN BATTISTA FERRARA

In Vitro Production of a Human HLA Alloantibody of Restricted Specificity (DQw2) Via Epstein-Barr Virus Transformation

DAVID ZOSCHKE and MIRIAM SEGALL Dw Subtypes of DR4 in Rheumatoid Arthritis: Evidence for a Preferential Association with Dw4

16

3O

44

68

75

85

97

109

118

Human Immunology Volume 15, Number 2, February 1986

Contents

JAN J. BLANKERT, LEENDERT A. van ES, HEINZ W. KUNZ, DONALD V. CRAMER, and LEENDERT C. PAUL

Genetics of the Antibody Response to an Endothelial Transplantation Antigen in the Rat

TAKAO NEGORO and NOBUYUKI TANIGAKI Serological and Functional Analysis of the Epitope Clusters and Leu3/T4 Antigen

PETERJ. KNUDSEN and JACK L. STROMINGER A Monoclonal Antibody That Recognizes the ce Chain of HLA-DR Antigens

YAEL GOTHELF, NATHAN SHARON, and EPHRAIM GAZIT A Subset of Human Cord Blood Mononuclear Cells Is Similar to Langerhans Cells of the Skin: A Study with Peanut Agglutinin and Monoclonal Antibodies

Y. MITSUISHI, A. FALKENRODT, A. URLACHER, M. M. TONGIO, and S. MAYER

New Human MHC Class I Antigens Segregating with HLA-A Antigens Detected on Some Lymphocyte Subpopulations

ROBERT W. KARR, SUSAN H. HSU, and WILMA B. BIAS Cells Homozygous for Two HLA-DR7-Associated HLA-D Specificities Express Highly Similar DR Molecules but Different DQ Molecules

VINCENT R. BONAGURA, CHRISTINE ROHOWSKY-KOCHAN, ELAINE REED, AVERIL MA, JOAN McDOWELL, DONALD W. KING, and NICOLE SUCIU-FOCA

Brief Definitive Report: Perturbation of the Immune Network in Herpes Gestationis

PIERGIORGIO NATALI, ALDO BIGOTTI, RENATO CAVALIERI, M, RITA NICOTRA, RAFFAELE TECCE, DANTE MANFREDI, YU-XIEN CHEN, LEE M. NADLER, and SOLDANO FERRONE

Gene Products of the HLA-D Region in Normal and Malignant Tissues of Nonlymphoid Origin

DAVID D. ECKELS, ARMEAD H. JOHNSON, ROBERT J. HARTZMAN, and DEBBIE DACEK

Clonal Analysis of HLA-DPwl (SB1) Associated Allodeterminants: Recognition of Novel Epitopes and Evidence for Quantitative Variation in Class II Antigen Expression

125

137

150

164

175

198

211

220

234

Human Immunology Volume 15, Number 3, March 1986

Contents

MARLEEN JANSON, JANICE McFARLAND, and RICHARD H. ASTER Quantitative Determination of Platelet Surface Alloantigens Using a Monoclonal Probe

M. R. J. KOHONEN-CORISH and S. W. SERJEANTSON HLA-DR/3 Gene DNA Polymorphisms Revealed by Tag I Correlate with HLA-DR Specificities

JEAN MICHON, GHISLAINE STERKERS, ALAIN HAZIOT, ANNE C. FREIDEL, LUCETTE GEBUHRER, HERVI~ BETUEL, ELISABETH GOMARD, YVETTE HENIN, VIRGINIA LEPAGE, DOMINIQUE J. CHARRON, and JEAN-PAUL LEVY

Despite a Lack of Monospecific Anti-DRwl3 Sera, a Corresponding Class II Determinant Can Be Defined by a DRw13 Restricted Anti-Influenza Virus T Cell Clone

YOSHIKI MATSUI, DONALD E. STAUNTON, HOWARD M. SHAPIRO, and EDMOND J. YUNIS

Comparison of MHC Antigen Expression on PHA- and MLC-Induced T Cell Lines with That on T and B Lymphoblastoid Cell Lives by Cell Cycle Dependency

FRI~DERIC TRIEBEL, SABINE De ROQUEFEUIL, CATHERINE BLANC, DOMINIQUE J. CHARRON, and PATRICE DEBRE

Expression of MHC Class II and Tac Antigens on IL2-Activated Human T Cell Clones That Can Stimulate in MLR, AMLR, PLT and Can Present Antigen

STEVEN K. H. FOUNG, BEHNAZ TAIDI, DOLLY NESS, and F. CARL GRUMET A Monoclonal Antibody Against HLA-Al l and A24

TOBIN M. SCHNEIDER, JERZY W. KUPIEC-WEGLINSKI, EDWARD TOWPIK, TERRY B. STROM, and NICHOLAS L. TILNEY

Studies on Mechanisms of Acute Rejection of Vascularized Organ Allografts

J. BERTRAMS, W. LUBOLDT, K. DANNEHL, and M. P. BAUR Homogeneity of HLA-DQ,DR Phenotypes in Lymphocyte Subsets of Normal Individuals

M. SEGALL, H. NOREEN, L. SCHLUENDER, and F. H. BACH DNA Restriction Fragment Length Polymorphisms Characteristic for Dw Subtypes of DR2

251

263

272

285

302

316

320

330

336

Human Immunology Volume 15, Number 4, April 1986

Contents

Foreword

FRANS H. J. CLAAS, JAN M. van REE, WIM M. A. VERHOEVEN, JAN J. van der POEL, WILLEM VERDUYN, DAVID de WIED, and JON J. van ROOD

The Interaction Between 3'-Type Endorphins and HLA Class I Antigens

MICHAEL EDIDIN Major Histocompatibility Complex Haplotypes and the Cell Physiology of Peptide Hormones

CHESTER A. ALPER, ZUHEIR L. AWDEH, and EDMONDJ. YUNIS Complotypes, Extended Haplotypes, Male Segregation Distortion, and Disease Markers

KAREN ARTZT Genetic Analysis of the T/t Complex

CHARLES AUFFRAY and JIRI NOVOTNY Speculations on Sequence Homologies Between the Fibronectin Cell- Attachment Site, Major Histocompatibility Antigens, and a Putative AIDS Virus Polypeptide

EDWARD A. BOYSE HLA and the Chemical Senses

JAN KLEIN, DAGMAR KLEIN, and FELIPE FIGUEROA Should the Neuraminidase-1 Locus Be Considered as Part of the Major Histocompatibility Complex?

PERRIN C. WHITE, JANET WERKMEISTER, MARIA I. NEW, and BO DUPONT Steroid 21-Hydroxylase Deficiency and the Major Histocompatibility Complex

JOHN J. MONACO and HUGH O. McDEVITT The LMP Antigens: A Stable MHC-Controlled Multisubunit Protein Complex

345

347

357

366

374

381

391

396

404

416