break through2020 VIRTUAL SUMMIT

MON, SEPT 28 & TUE, SEPT 29 • 11am - 1pm

SCHEDULEDAY 1 MONDAY, SEPT 2811:00-11:05 Welcome from Joni Johnson, SD Biotech Executive Director

11:05-12:00 SBA Keynote“Growing Opportunities through SBIR/America’s Seed Fund”Brittany Sickler, Senior Innovation Policy Advisor, Office of Innovation and Technology, Office of Investment and Innovation, U.S. Small Business Administration

Keynote“SBIR Grants – A Case Study”Sue Lancaster, SD Biotech Board President and Vice President of Corporate Development for South Dakota Innovation Partners

12:00-12:15 Biotransformation Update

12:15-1:15 BIOSCIENCE PANEL“Bioscience Post COVID-19: Opportunities & Challenges in Feeding, Fueling and Healing Industry Sectors” Eddie Sullivan, Ph.D.. SAB Biotherapeutics Joe Jump, Senior Scientist, Novozymes Alan Berry, Ph.D., Senior Director of Microbial Development, Novozymes MODERATOR: Steve Lewis, VP Technology & Innovation, POET

DAY 2 TUESDAY, SEPT 2911:00-11:05 Welcome from Sue Lancaster, SD Biotech Board President

11:05-12:00 NASA Keynote “Supplier Fraud and the Loss of Two Taurus XL Rockets. NASA Lessons Learned.”Wade A. Krieger, Special Agent, NASA Office of the Inspector General (OIG)

12:00-12:15 USD Discovery District Update12:15-1:15 Meet South Dakota Manufacturers Specializing in the Life Sciences. MANUFACTURING PANEL Kyle Bender, Director of Manufacturing Technology Falcon Plastics Gary Larson, President, Electronic Systems Inc. (ESI) Ryan Carlson, Manager, Quality & Regulatory Affairs, Spartronics Dani Mason, Marketing and Sales Director, B9Creations MODERATOR: Mark Brown, Ph.D., President, USD Discovery District

ABOUT OUR SPEAKERSDAY 1 • MONDAY, SEPT 28SBA KeynoteBrittany Sickler Senior Innovation Policy Advisor, Office of Innovation and Technology, Office of Investment and Innovation, U.S. Small Business Administration

“Growing Opportunities through SBIR/America’s Seed Fund”

Brittany Sickler serves as Senior Innovation Policy Advisor for the SBA’s Office of Investment and Innovation. Her primary duties support the advancement of the Small Business Innovation Research/Small Business Technology Transfer (SBIR/ STTR) programs, which enable small businesses to explore their technological potential and profit from its commercialization. She oversees initiatives to increase understanding of SBIR/STTR opportunities with SBA offices and partner networks across the country, as well as manages the agency’s Federal and State Technology (FAST) Partnership Program. Brittany spent almost four years in SBA’s North Dakota District Office as an Economic Development Specialist, building and strengthening connections throughout the state, particularly with regional startup networks and rural communities. She also served as Special Advisor in SBA’s Office of Entrepreneurial Development, advancing strategic initiatives and coordinating SBA’s first Virtual Conference.

Prior to SBA, Brittany served in Guatemala as a Peace Corps Volunteer and Volunteer Leader in the Sustainable Community Tourism program, a combination of economic development and environmental conservation. She was a Masters International Fellow, completing a Master’s in International Community Economic Development from Southern New Hampshire University. She also holds degrees in Business Administration and Spanish from Indiana Wesleyan University. Her career in economic development started in Southern Florida with microlender ACCION USA, providing small business loans to individuals who could not access traditional credit.

“SBIR Grants – A Case Study”Sue LancasterSD Biotech Board President and Vice President of Corporate Development for South Dakota Innovation Partners

Biotransformation Update.

Bioscience Post COVID-19: Opportunities & Challenges in Feeding, Fueling and Healing Industry Sectors.

BIOSCIENCE PANELEddie Sullivan, Ph.D. - SAB Biotherapeutics - www.sabbiotherapeutics.comA natural match for the complexity of human disease.Modern medicine struggles to keep pace with the emergence, mutation, and diversity of disease. The body’s natural defense system produces polyclonal antibodies against invaders such as viruses, allergens, bacteria, toxins, and other pathogens.

SAB Biotherapeutics has developed a first-of-its-kind therapeutic engine—unleashing the power of the body’s native biological defense system to produce immunotherapies that truly match and overpower the complexity, diversit, and evolution of human disease.This new class of immunotherapies opens the door to new medicines that are safer, more effective and longer lasting than current antibody therapies.

Joe Jump - Senior Scientist, Novozymes - www.novozymes.comAlan Berry, Ph.D. - Senior Director of Microbial Development, Novozymes - www.novozymes.comNovozymes is the world leader in bioinnovation. We work with our partners to innovate new solutions and rethink industries around the world. Our industrial enzymes, microorganisms, biopolymers and other proteins allow our customers to achieve more efficient use of raw materials, reduce energy consumption, replace traditional chemicals with more sustainable alternatives and offer higher-quality products. We rethink everyday products every day.

MODERATOR: Steve Lewis VP Technology & Innovation, POET – poet.comPOET is a proud leader in the sustainable energy industry. For over thirty years we've been turning one big idea after another into biofuel and renewable alternative product solutions.

SCHEDULEDAY 1 MONDAY, SEPT 2811:00-11:05 Welcome from Joni Johnson, SD Biotech Executive Director

11:05-12:00 SBA Keynote“Growing Opportunities through SBIR/America’s Seed Fund”Brittany Sickler, Senior Innovation Policy Advisor, Office of Innovation and Technology, Office of Investment and Innovation, U.S. Small Business Administration

Keynote“SBIR Grants – A Case Study”Sue Lancaster, SD Biotech Board President and Vice President of Corporate Development for South Dakota Innovation Partners

12:00-12:15 Biotransformation Update

12:15-1:15 BIOSCIENCE PANEL“Bioscience Post COVID-19: Opportunities & Challenges in Feeding, Fueling and Healing Industry Sectors” Eddie Sullivan, Ph.D.. SAB Biotherapeutics Joe Jump, Senior Scientist, Novozymes Alan Berry, Ph.D., Senior Director of Microbial Development, Novozymes MODERATOR: Steve Lewis, VP Technology & Innovation, POET

DAY 2 TUESDAY, SEPT 2911:00-11:05 Welcome from Sue Lancaster, SD Biotech Board President

11:05-12:00 NASA Keynote “Supplier Fraud and the Loss of Two Taurus XL Rockets. NASA Lessons Learned.”Wade A. Krieger, Special Agent, NASA Office of the Inspector General (OIG)

12:00-12:15 USD Discovery District Update12:15-1:15 Meet South Dakota Manufacturers Specializing in the Life Sciences. MANUFACTURING PANEL Kyle Bender, Director of Manufacturing Technology Falcon Plastics Gary Larson, President, Electronic Systems Inc. (ESI) Ryan Carlson, Manager, Quality & Regulatory Affairs, Spartronics Dani Mason, Marketing and Sales Director, B9Creations MODERATOR: Mark Brown, Ph.D., President, USD Discovery District

ABOUT OUR SPEAKERSDAY 2 • TUESDAY, SEPT 29NASA KeynoteWade A. KriegerSpecial Agent, NASA Office of the Inspector General (OIG)

“Supplier Fraud and the Loss of Two Taurus XL Rockets. NASA Lessons Learned.”

Special Agent (SA) Krieger is a career criminal investigator with 30 years of experience serving two federal law enforcement agencies. For the past 20 years, SA Krieger has worked for NASA OIG at Kennedy Space Center, FL, and has handled numerous successful white-collar criminal and civil investigations to include product substitution, theft of trade secrets, grant fraud, lease fraud, conflicts of interest, conspiracy, embezzlement, theft and various other procurement-related cases. He has been a regular guest instructor at the Federal Law Enforcement Training Center’s Product Substitution course since 2008 and is a 2019 graduate of the FBI National Academy, Class 276.

SA Krieger began his law enforcement career as a Special Agent with the Air Force Office of Special Investigations (AFOSI) in 1989 after graduating from Memphis State University and receiving a US Air Force commission via Air Force ROTC. While on active duty, SA Krieger served tours in Arkansas, Guam, Panama, and Florida. He commanded the Panama Jack Task Force, a unique tri-service, counter-smuggling unit based in the Republic of Panama from 1993 to 1995 and commanded AFOSI Detachment 419, Tyndall AFB, FL, from 1995 to 1998. While serving the Air Force, SA Krieger conducted and supervised cases involving narcotics distribution, smuggling, illegal weapons, counterfeit currency, counterintelligence matters, rape, aggravated assault, armed robbery, child abduction / abuse and homicide and has coordinated successful prosecutions with state, federal, military and foreign prosecutors in numerous locations. In 1999, SA Krieger transitioned from active duty and became a reserve AFOSI Officer. He is an Air Command and Staff College graduate and retired from the Air Force Reserves in 2010 as a Lieutenant Colonel.

Meet South Dakota Manufacturers Specializing in the Life Sciences.MANUFACTURING PANELKyle Bender, Director of Manufacturing Technology, Falcon Plastics – www.falconplastics.comFounded in 1975 by Don and Carol Bender, Falcon Plastics has been molding customer ideas into a wide variety of products used every day, by people all over the world. From medical and pharmaceutical products to common household items, Falcon Plastics has the capacity to see your project through from design concept to a finished product that is ready for market. Falcon has the vision and capacity to engineer, manufacture, assemble and distribute your product in the leanest, most effective way.

Gary Larson, President, Electronic Systems Inc. (ESI) – www.electronicsi.comElectronic Systems, Inc. (ESI) provides a full range of electronics manufacturing services to leading original equipment manufacturers (OEMs). For over 35 years, our customers have trusted us to help them improve their product quality and costs. We currently serve companies in the industrial, commercial, medical, energy and HVAC industries. Our legacy of Legendary Service is based on a simple, 5-point formula: Serve the customer first, Focus on long-term relationships, Lean manufacturing expertise, A culture of empowered associates, Financial strength.

Ryan Carlson, Manager, Quality & Regulatory Affairs, Spartronics – www.sparton.comFor over a century, Spartronics has been an industry leader in designing, developing, and manufacturing some of the world’s most complex electronics and electromechanical devices. Spartronic’s Watertown, SD, location serves medical and high-end industrial customers in regulated and complex environments with their electromechanical needs. We can be your partner along the entire value chain from early prototyping and design evaluation through supply chain management and aftermarket services.

Dani Mason, Marketing and Sales Director, B9Creations - www.b9c.comB9Creations was built on the belief that 3D printing technology could serve businesses better and more profitably. By taking feedback from our customers and combining it with our patented technology, we bring you 3D printing solutions designed to exceed expectations.

MODERATOR: Mark Brown, Ph.D., President, USD Discovery District - www.usddiscovery.comThe USD Discovery Disctrict will provide an environment where university research can be conducted and commercialized and a resource to help grow companies in South Dakota. The District will help connect universities with innovation-driven businesses that are in the entrepreneurial stages or expanding. Tenants are expected to establish relationships with university faculty and students or engage in activities related to research in Regental institutions.

THANK YOU TO OUR SPONSORSpresenting sponsor presenting sponsorBIO – www.bio.org PhRMA – www.phrma.org

gold sponsor gold sponsorFisher Scientific – www.fishersci.com SAB Biotherapeutics — www.sabbiotherapeutics.com

gold sponsor silver sponsorSD EPSCoR – sdepscor.org Fredrikson & Byron – www.fredlaw.com

additional sponsorsSD Manufacturering & Technology Solutions – www.sdmanufacturing.com

BIO is the world's largest trade association representing biotechnology companies, academic institutions, state biotechnology centers and related organizations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative health care, agricultural, industrial and environmental biotechnology products. The key areas of focus for BIO are: health care, emerging companies, intellectual property, industrial & environmental, food & agriculture, public policy and international policy.

The Pharmaceutical Research and Manufacturers of America (PhRMA) represents the country’s leading innovative biopharmaceutical research companies, which are devoted to discovering and developing medicines that enable patients to live longer, healthier and more productive lives. Since 2000, PhRMA member companies have invested more than $900 billion in the search for new treatments and cures, including an estimated $79.6 billion in 2018 alone.

Fisher Scientific offers customers convenient access to a complete portfolio of laboratory equipment, chemicals, supplies and services used in scientific research, health care, safety and education markets. A global network of direct sales professionals, industry-specific catalogs, e-commerce capabilities and supply-chain management services enables Fisher Scientific to offer a broad mix of products manufactured by Thermo Fisher Scientific and third parties.

Fredrikson & Byron was founded in Minneapolis in 1948. Since then, we’ve grown into an international firm of over 280 attorneys in over 35 practice and industry areas, serving clients from seven offices worldwide. We serve a broad variety of publicly and privately held businesses, financial institutions, municipalities, professional corporations, limited liability companies, nonprofits, trade associations, partnerships and individuals. Clients include new ventures, small and medium-sized companies, family businesses, and national and international companies traded on world stock exchanges.

SD MTS is a business transformation services company, offering a host of services designed specifically for South Dakota manufacturers.

In 1980, the National Science Foundation (NSF) established the Experimental Program to Stimulate Competitive Research (EPSCoR). The EPSCoR program is designed to assist states to establish a self-sustaining academic research enterprise with the competitive capability that will contribute to the states’ economic viability and development. SD EPSCoR’s mission is to strengthen research and education in science, technology, engineering and mathematics (STEM) across South Dakota to increase science literacy and drive science-based economic development. SD EPSCoR helps build South Dakota’s research infrastructure and increases its capacity to successfully compete for federal funding.

SAB Biotherapeutics Inc. (SAB) is a biopharmaceutical company on the leading edge of innovation, developing natural technologies that have the potential to transform the treatment and prevention of diseases from cancer to Ebola and diabetes to influenza. SAB’s first-of-its-kind therapeutic production platform holds the promise of treatment of rare conditions, long-term diseases and global pandemic threats.