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Vertebrate Embryonic Patterning 7 Left-Right Axis Polarity

Vertebrate Embryonic Patterning 7

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Vertebrate Embryonic Patterning 7. Left-Right Axis Polarity. Chick. Mouse. Asymmetric Gene Expression Establishes Left-Right Axis. Shh Induces Nodal. nodal expression. Asymmetric Expression at the Node. Shh. Act RIIa. Asymmetric Expression in Lateral Plate Mesoderm. caronte. nodal. - PowerPoint PPT Presentation

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Page 1: Vertebrate Embryonic Patterning 7

Vertebrate Embryonic Patterning 7

Left-Right Axis Polarity

Page 2: Vertebrate Embryonic Patterning 7

Asymmetric Gene Expression Establishes Left-Right AxisChick

Mouse

Page 3: Vertebrate Embryonic Patterning 7

Shh Induces Nodal

nodal expression

Page 4: Vertebrate Embryonic Patterning 7

Asymmetric Expression at the Node Shh Act RIIa

Page 5: Vertebrate Embryonic Patterning 7

Asymmetric Expression in Lateral Plate Mesoderm

caronte nodal pitx-2

lateral plate mesoderm

heart tubeA&C ventral views, B dorsal view

Page 6: Vertebrate Embryonic Patterning 7

Nodal Expression in Lateral Plate of Mouse Embryo

nodal

situs inversus viscerum (iv)

mutant

Page 7: Vertebrate Embryonic Patterning 7

Asymmetries in Vertebrate Organogenesis