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U.S. Trends in Births & Infant Deaths U.S. Department of Health and Human Services Centers for Disease Control and Prevention National Center for Health Statistics National Vital Statistics System

U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

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Page 1: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

U.S. Trends in Births& Infant Deaths

U.S. Department of Health and Human ServicesCenters for Disease Control and Prevention

National Center for Health StatisticsNational Vital Statistics System

Page 2: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Authors / Acknowledgements

Joyce A. Martin, M.P.H.Kenneth D. Kochanek, M.A.Paul D. Sutton, Ph.D.Donna L. Hoyert, Ph.D.Stephanie Ventura, M.A.Charles J. Rothwell, M.S.

Presented to the Secretary’s Advisory Committee on Infant Mortality, 7/13/04

Page 3: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

NATIONAL VITAL STATISTICS SYSTEM

Live birthsFetal deaths

(>20 weeks)Infant deaths(to age 1)

Certificate of Live birth

Certificate of Death

Report of Fetal Death

Page 4: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Model State Vital Statistics Act and Regulations - Definitions

Live birth - “…breaths or shows any evidence of life such as beating of the heart…heartbeats are to be distinguished from transient cardiac contractions; respirations…from fleeting efforts…”

Fetal Death - “… death prior to [delivery]…is not an induced termination of pregnancy… does not breathe or show any other evidence of life…”

Infant Death - death of a live born infant within one year of life.

Page 5: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Distribution of live births by race and Hispanic origin: U.S., 2002

(N = 4,021,726)

Non-Hisp White57%

Non-HispBlack14%

Hispanic22%

American Indian1.5%

Asian/Pacific Islander5%

Page 6: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

1st trimester prenatal care by race and Hispanic origin: U.S., 1990-2002

50

60

70

80

90

100

1990 1995 2000

Perc

ent

SOURCE: National Vital Statistics System, NCHS, CDC.

HispanicNon-Hispanic black

Non-Hispanic white

2002

All races

American Indian

0

Page 7: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Preterm and low birthweight rates: U.S., 1981-2002

5

10

15

1981 1985 1990 1995 2000 2002

Perc

ent

NOTE: Preterm is less than 37 completed weeks of gestation. Low birthweight is less than 2,500 grams.SOURCE: National Vital Statistics System NCHS CDC

Low birthweight (<2,500 grams)

Preterm (<37 weeks)

0

Page 8: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Preterm birth rates by race:U.S., 2002

0

5

10

15

20

Black Am Ind Hispanic White API

Perc

ent

SOURCE: National Vital Statistics System, NCHS, CDC.

13.1

10.411.011.6

17.7

Non-Hispanic Non-Hispanic

Very pretermModerately preterm

U.S.

Page 9: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Low birthweight rates by race:U.S., 2002

0

5

10

15

Black API Am Ind White Hispanic

Perc

ent

SOURCE: National Vital Statistics System, NCHS, CDC.

7.87.2

6.56.9

13.4

Non-Hispanic Non-Hispanic

Very low birthweightModerately low birthweight

U.S.

Page 10: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Twin and triplet birth rates: United States, 1980-2002

10

15

20

25

30

35

1980 1985 1990 1995 2000 2002

Ra

te p

er

1,0

00

liv

e b

irth

s

NOTE: Twin birth rate is the number of live born infants in twin deliveries per 1,000 live births.SOURCE: National Vital Statistics System, NCHS, CDC.

0

50

100

150

200

250

1980 1985 1990 1995 2000 2002

Rate

per

100,0

00 liv

e b

irth

s

NOTE: Triplet+ birth rate is the total number of live born infants in triplet+ deliveries per 1,000 live births. Triplet+ includes births in greater than twin deliveries.SOURCE: National Vital Statistics System, NCHS, CDC.

Twin Triplet

Page 11: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Preterm and low birthweight ratesby plurality: U.S., 2002

0102030405060708090

100

Singletons Twins Triplet/+ Singletons Twins Triplet/+

Perc

ent

SOURCE: National Vital Statistics System, NCHS, CDC.

Low birthweightVery preterm / very low birthweight

Preterm

10.1

94.7

55.4

6.1

92.7

58.2

Page 12: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Infertility TherapiesIncreased risk

of multiple births

Increased riskof preterm/lbw

singleton births ?

Assisted Reproductive Technologies =1% of all 2001 births

Page 13: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Percent low birthweight for all birthsand for singletons only: U.S., 1980-2002

4

6

8

10

1980 1985 1990 1995 2000 2002

Perc

ent

NOTE: Low birthweight is less than 2,500 grams.SOURCE: National Vital Statistics System, NCHS, CDC.

All births/pluralities

Singletons

0

Page 14: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Preterm birth rates for singletons: U.S. 1990 and 2002

0

2

4

6

8

10

12

1990 2002 1990 2002 1990 2002

Perc

ent

1.69 1.57

8.878.01

VeryPreterm

Moderatelypreterm

9.7010.44

Preterm

Page 15: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Rates of induction of labor bylength of gestation: U.S., 1990-2002

0

2

4

6

8

10

12

14

16

18

20

1990 1995 2000 2002

Perc

ent

NOTES: Oklahoma did not report induction in 1990.SOURCE: National Vital Statistics System, NCHS, CDC.

Moderately preterm (32-36 weeks)

Very preterm (<32 weeks)

Page 16: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Rates of cesarean delivery by lengthof gestation: United States, 1990-2002

0

10

20

30

40

50

60

1990 1995 2000 2002

Perc

ent

SOURCE: National Vital Statistics System, NCHS, CDC.

Very preterm (<32 weeks)

Moderately preterm (32-36 weeks)

Page 17: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Early and late fetal mortality rates: U.S. 1990-2001

0

2

4

6

1990 1995 2000 2001

Rat

e pe

r 1,0

00 li

ve b

irths

+ fe

tal d

eath

s

Late fetal

Early fetal

Source: National Vital Statistics System, NCHS, CDC.

Early fetal mortality rate = fetal deaths with stated or presumed gestationalages of <28 weeks per 1,000 live births plus fetal deaths. Late fetal mortalityrate = deaths with stated or presumed gestational ages of 28 weeks or moreper 1,000 live births plus fetal deaths.

Page 18: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Infant mortality rate: United States, 1940-2001

0

20

40

60

1940 1950 1960 1970 1980 1990 2001

Dea

ths

unde

r 1 y

ear p

er 1

,000

live

birt

hs

SOURCE: National Vital Statistics System, NCHS, CDC.

Page 19: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Neonatal, post neonatal and infant mortality rates by race and Hispanic origin: U.S., 2001

0

5

10

15

Black Am Ind White Hispanic API

Per 1

,000

live

birt

hs

SOURCE: National Vital Statistics System, NCHS, CDC.

9.7

5.74.75.4

13.5

(Non-Hispanic) (Non-Hispanic)

Neonatal

Post neonatal

Page 20: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Distribution of 5 leading causesof infant death: U.S., 2001

(N = 27,523)

CongenitalAnom20%

Preterm/LBW16% SIDS

8%

Resp distress 4%

All other causes47%

Maternal Compl 5%

SOURCE: National Vital Statistics System, NCHS, CDC.

Page 21: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Distribution of 4 Leading causes ofinfant death by race of mother: U.S., 2001

PT/LBW14%Con

Anom24%

SOURCE: National Vital Statistics System, NCHS, CDC.

Con Anom12%

SIDS 8%SIDS 9%

White 18,087 Black 8,084

Comp 6%

All other causes50%

PT/LBW22%

Comp 6%

All other causes51%

Page 22: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Percent of all infants born LBW* and neonatal mortality rates among LBW infants : U.S., 1990, 1995, 2001

0

15

30

45

60

75

1990 1995 2001

Per

1,0

00

0

5

10

1990 1995 2001

Perc

en

t

Neonatal mortalityat <2,500 grams

Percent of infants<2,500 grams

*LBW=<2,500 gramsSource: National Vital Statistics System, CDC, NCHS.

Page 23: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Infant mortality rate: United States, 1990-2002

5

6

7

8

9

10

1990 1992 1994 1996 1998 2000 2002*

Dea

ths

unde

r 1 y

ear p

er 1

,000

live

birt

hs

0

* Preliminary data.

SOURCE: National Vital Statistics System, NCHS, CDC.

+3%

Page 24: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Preliminary infant mortalityrates by race, 2001-2002

Non-Hispanic white:5.7 to 5.9* per 1,000

Black:14.0 to 14.3 per 1,000

*Statistically significant at .05

Page 25: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Infant deaths and infant, neonatal, and postneonatal mortality rates: United States, preliminary 2002, and final 2001

[Rates per 1,000 live births]

Infant mortality rate

Infantdeaths

Neonatal (Under 28 days) Postneonatal (28 days –11 months)Year Total Total

Under 7 days

7-27 days

2002 1 28,042 7.0 4.7 3.7 0.9* 2.3

2001 27,568 6.8 4.5 3.6 0.9 2.31 Partially edited data processed through January 2004.*2001 =0.908, 2002 = 0.931

NOTE: Bold underlined numbers indicate a statistically significant difference with the previous year.SOURCE: National Vital Statistics System, NCHS, CDC.

Page 26: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Early and late neonatal and postneonatal mortality rates: U.S., 1990-2002

0

1

2

3

4

5

6

1990 1995 2000 2002

Rat

e pe

r 1,0

00 li

ve b

irths

Note: Rates for 2002 are based on partially edited data processed as of January, 2004.

Postneonatal

Late neonatal

Early neonatal mortality rate = deaths to infant < 7 days per 1,000 live births. Late neonatal mortality rate = deaths to infants 7-27 days. Postneonatal mortality rate = deaths to infants 28 days - 1 year per 1,000 live births.

Source: National Vital Statistics System, NCHS, CDC.

Early neonatal

Page 27: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

[Rates per 100,000 live births]

2 Preliminary data for 2002 processed through July 10, 2003.

SOURCE: National Vital Statistics System, NCHS, CDC.

1 World Health Organization. International Statistical Classification of Diseases and Related Health Problems, Tenth Revision. Geneva: World Health Organization. 1992.

37.242.9Newborn affected by maternal complications of pregnancy

55.550.6Sudden infant death syndrome

109.5114.4Disorders relating to short gestation and low birthweight, not elsewhere classified

136.9140.7Congenital malformations, deformations and chromosomal abnormalities

20012002 2Cause of death 1

Infant mortality rates by leading causes: United States, preliminary 2002, and final 2001

Page 28: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Perinatal, late fetal, and early neonatal mortality rates, 1990-2002

0

2

4

6

8

10

1990 1995 2000 2002

Rat

e pe

r 1,0

00 li

ve b

irths

Note: Rates for 2002 are based on partially edited data processed as of January, 2004.

Late fetal

Early neonatal

Perinatal mortality

Early neonatal mortality rate = deaths to infants <7 days per 1,000 live births.Late fetal mortality rate = fetal deaths with stated or presumed gestational ages of 28 weeks or more per 1,000 live births plus late fetal deaths.

Perinatal mortality rate = late fetal deaths plus infant deaths <7 days per 1,000 live births plus late fetal deaths.

Source: National Vital Statistics System, NCHS, CDC.

Page 29: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

SupplementalAnalyses

Page 30: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Stay tuned….

Data from the Linked Birth/Infant Death Data Set will allow us to more fully explain this troubling change in infant mortality for 2002

Report scheduled for release late summer 2004

Page 31: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

Re-engineered vital statistics systems

More immediate, more thorough analysis

More timely, higher quality data Data released within months of event Births/infant deaths automatically linked – data

available simultaneously

New, improved items Pregnancy risk factors - Infertility therapies,

hypertension Infections Method of delivery Pregnancy status at death

Page 32: U.S. Trends in Births & Infant Deaths...Singletons Twins Triplet/+ Singletons Twins Triplet/+ Percent SOURCE: National Vital Statistics System, NCHS, CDC. Low birthweight Very preterm

www.cdc.gov/nchs/nvss.htm