UNITED STATES OF AMERICA BEFORE THE FEDERAL TRADE …€¦ · 3. Respondents have advertised, offered for sale, sold, and administered at least 10 different intravenous cocktails

UNITED STATES OF AMERICA BEFORE THE FEDERAL TRADE COMMISSION

COMMISSIONERS Joseph J Simons Chairman Maureen K Ohlhausen Noah Joshua Phillips Rohit Chopra Rebecca Kelly Slaughter ________________________________________________ In the Matter of A amp O ENTERPRISES INC a corporation dba iV BARS INCORPORATED and iV BARS and DOCKET NO C- AARON K ROBERTS aka Aaron Keith individually and as owner and operating manager of A amp O ENTERPRISES INC ________________________________________________

COMPLAINT

The Federal Trade Commission having reason to believe that A amp O Enterprises Inc a

corporation and Aaron K Roberts individually and as owner and operating manager of A amp O Enterprises Inc (collectively ldquoRespondentsrdquo) have violated provisions of the Federal Trade Commission Act and it appearing to the Commission that this proceeding is in the public interest alleges 1 Respondent A amp O Enterprises Inc (ldquoiV Barsrdquo) also doing business as iV Bars Incorporated

and iV Bars is a Wyoming corporation with its principal office or place of business at 4101 Centurion Way Addison Texas 75001

2 Respondent Aaron K Roberts also known as Aaron Keith is the owner and operating

manager of iV Bars Individually or in concert with others he controlled or had the authority to control or participated in the acts and practices of iV Bars including the acts and practices alleged in this Complaint His principal office or place of business is the same as that of iV Bars

3 Respondents have advertised offered for sale sold and administered at least 10 different

intravenous cocktails (ldquoiV Cocktailsrdquo) to consumers including the Myers Cocktail and Immune Booster Respondentsrsquo iV Cocktails or ldquobagsrdquo contain mixtures of water vitamins minerals and amino acids infused directly into the bloodstream through an intravenous drip typically through a vein in the arm These iV Cocktails cost $10000 or more per session Respondents refer to these treatments among other things as ldquoIntravenous Micro-Nutrient

Therapyrdquo ldquoIntravenous Vitamin Therapyrdquo ldquoHydration Therapyrdquo or simply ldquoiV Therapyrdquo Respondents claimed that their iV Cocktails could be used to treat consumers suffering from serious diseases including cancer congestive heart failure multiple sclerosis diabetes fibromyalgia and neurodegenerative disorders Respondents further claimed that their iV Cocktails produced fast lasting results and in many instances were more effective and better tolerated than conventional medical therapies Respondents also touted their iV Cocktails as hangover cures and a way to replenish fluids and essential vitamins and minerals In addition Respondents offered several intramuscular treatments that directly inject mixtures into human muscle Respondentsrsquo iV Cocktails and intramuscular treatments are ldquodrugsrdquo within the meaning of Sections 12 and 15 of the Federal Trade Commission Act

4 Respondentsrsquo first and primary iV Bars location is housed in a NextGen Wellness Center an

upscale gym and clinic that independently offers chiropractic care pain management therapy physical therapy medical massages and counseling New iV Bars customers create an online account and complete a short health assessment questionnaire when making their first appointment Respondents have an arrangement with a doctor who does a quick online review of all health assessment questionnaires that customers submit to iV Bars Respondents pay the doctor a flat fee of $250 per month for this service Shortly before the customer arrives an iV Bars employee takes about five minutes to mix ingredients obtained from a local compounding pharmacy into the customerrsquos requested iV Cocktail Once at iV Bars the customer is asked to sign a release form that discloses risks and releases Respondents from liability Thereafter an iV Bars nurse seats the customer in one of five oversized reclining chairs and administers the iV Cocktail to them over a 25-45 minute period Respondents also maintain a ldquofull service mobile vehiclerdquo that allows them to ldquocome right to your door to deliver the treatment of your needsrdquo

5 The acts or practices of Respondents alleged in this Complaint have been in or affecting

commerce as ldquocommercerdquo is defined in Section 4 of the Federal Trade Commission Act

iV Bars Efficacy Claims 6 Beginning at least as early as August 2015 Respondents have disseminated or caused to be

disseminated advertisements for their iV Cocktails including through company Facebook Twitter and Instagram accounts and company websites including the ivbarscom website (imaged on January 27 2017) attached as Exhibit A (ldquoiV Bars Websiterdquo or ldquoWebsiterdquo) As described below the iV Bars Website contained the following statements and depictions among others

A On the top section of the Website homepage Respondents prominently offered ldquoMEDICAL iV TREATMENTSrdquo for among other things ldquoCANCERrdquo They also stated ldquoIf you are new to the concept of Intravenous vitamin Therapy you might be wondering why yoursquore suddenly hearing so much about it Why [it is] being relied upon by patients suffering from a very serious illness [It] represents an exciting new paradigm in integrative and functional medicine allowing us to both prevent and help treat a wide variety of conditions safely and effectivelyrdquo

(Exhibit A-1)

B The middle section of the Website homepage titled ldquoThe Science Behind iV Barsrdquo stated ldquoVitamins minerals and amino acids enter your bloodstream directly and immediately to help the body to begin healing itselfrdquo and claimed that iV Bars treatments were ldquoDeveloped by a team of leading medical doctors naturopathic doctors biochemists nutritionists and exercise physiologistsrdquo

(Exhibit A-1)

C The bottom section of the Website homepage titled ldquoOur Success Storiesrdquo contained brief endorsements of iV Bars by two sports figures and an international model and a link titled ldquoREAD MORE STORIESrdquo

(Exhibit A-1) Clicking the ldquoREAD MORE STORIESrdquo link took consumers to pages titled ldquoSUCCESS STORIESrdquo that described ldquocase studies about different disorders and the effects that iV therapy has had on these conditionsrdquo

(Exhibit A-3) These case study success stories included the following purported results

Case 3 Multiple Sclerosis A 65 year-old male with progressive multiple sclerosis presents to the clinic wheel chair bound The patient has tried medications physical therapy and speech therapy However there have been little noticeable benefits with regards to his leg strength and neurological function The patient received an intravenous infusion of glutathione After the first infusion he reported increased strength in his legs His physical therapist and caretaker also reported noticing an improvement in his leg strength and ability to walk Case4 Diabetic peripheral neuropathyRestless leg syndrome A 65 year-old male presents to the clinic with a ten plus year history of rheumatoid arthritis diabetes high blood pressure neuropathy and restless leg syndrome The patient was started on intravenous vitamin C and glutathione therapy After the fourth treatment the patientrsquos restless symptoms and joint pain was [sic] completely resolved Although the symptoms have returned they were not of the same intensity More Success Stories

Fibromyalgia Case 3 A 48-year-old woman presented with a six-year history of fairly constant myalgias and arthraigias with pain in the neck back and hip She was diagnosed by a rheumatologist as possibly having polymyalgia rheumatic [or] fibromyalgia The patient was given [a Myers Cocktail] At the end of the injection she got off the table and with a look of amazement announced her muscle aches and joint pains were gone for the first time in six years The author has given the Myersrsquo to approximately 30 patients with fibromyalgia half have experienced significant improvement in a few cases after the first injection but more often after three or four treatments Cardiovascular Disease Case 5 A 79-year-old man was seen at home in end-stage heart failure after having suffered four myocardial infarctions A peripheral angiogram revealed complete occlusion of both femoralpopliteal arteries with no detectable blood flow to the distal extremities [T]he cardiologist advised the patient that his heart would not last more than another month He was treated with weekly [intramuscular] injections After eight weeks the IM injections were replaced by weekly IV injections [of Myers Cocktail] The patient lived for eight years and died at age 87 from multiple organ failure Of the handful of other patients with angina or heart failure who received IV or IM injections all showed significant improvement

(Exhibit A-3 to 6)

D The Website homepage also contained tabs across the top that linked to other pages within the Website including a tab titled ldquoMEDICALrdquo On the Medical page under the heading ldquoWhy Driprdquo Respondents proclaimed ldquoIV drips bypass the gut delivering essential nutrients and fluids directly into the bloodstream This allows us to detoxify nourish and rehydrate our cells from the inside out for dramatic long-lasting and often instant resultsrdquo Under the Medical page subheadings ldquoBenefitsrdquo and ldquoConditionsrdquo Respondents listed numerous diseases and conditions including ldquoCancerrdquo ldquoCongestive heart failurerdquo ldquoDiabetesrdquo ldquoFibromyalgiardquo and ldquoNeurodegenerative disordersrdquo and claimed that Respondentsrsquo iV treatments produce ldquoFast lasting resultsrdquo

(Exhibit A-7)

E The iV Bars Website homepage also contained a tab titled ldquoMOBILErdquo that linked consumers to a page that described Respondentsrsquo ldquofull service mobile vehiclerdquo and proclaimed ldquoWe Are Mobile We Come To Yourdquo The Mobile page contained the same disease claims as the Medical page listing among the conditions that can be treated ldquoCancerrdquo ldquoCongestive heart failurerdquo ldquoDiabetesrdquo ldquoFibromyalgiardquo and ldquoNeurodegenerative disordersrdquo (Exhibit A-10)

F The iV Bars Website homepage also contained a tab titled ldquoSCIENCErdquo that linked consumers to multiple pages the first of which was titled ldquoTHE SCIENCE BEHIND iV Barsrdquo It stated ldquo[F]ew people realize that when you swallow a vitamin pill or a multi-vitamin the bodyrsquos natural absorption process can render up to 85 of that vitamin useless When you receive an ldquoiVrdquo the nutrients enter your bloodstream directly and immediately to help the body to begin healing itselfrdquo

(Exhibit A-11)

G The second page of the Science section began with the question ldquoARE YOU GETTING THE NUTRIENTS YOU NEEDrdquo and stated

Overwhelming scientific evidence confirms that vitamin deficiencies are associated with disease processes and the overall condition of onersquos health Vitamin mineral and antioxidant deficiencies has [sic] been shown to suppress immune function and contribute to chronic degenerative processes such as arthritis cancer Alzheimerrsquos cardiovascular disease and diabetes This body

of research has been reaffirmed by the journal of the American Medical Association (June 19 2002-Vol 287 No-23)

(Exhibit A-12)

iV Bars Establishment Claims

H In addition to the ldquoThe Science Behind iV Barsrdquo section of the iV Bars Website homepage (discussed in Part 5B above) the Website homepage contained a link titled ldquoABOUT iV BARS THE COMPANYrdquo that linked consumers to a page titled ldquoTHE COMPANY BEHIND THE BAGrdquo That page contained depictions of men and women dressed in white lab coats looking at test tubes and through microscopes It declared ldquoInspired by the early works of Dr Myers Aaron Keith founded iV Bars in 2015 He assembled a world class team of physicians biochemists and physiologists to create the formulas of iV Barsrdquo Thereafter under the subtitle ldquoiV Bars Research Labsrdquo Respondents claimed to have an ldquoapplied Biology and Chemistry Grouprdquo at a purported ldquoiV Bars Labsrdquo comprised of ldquoexperienced biologists chemists pharmacists medical and naturopathic doctors and exercise physiologistsrdquo to among other things ldquotest and approve inject-able formulations that are used in intravenous subcutaneous and intramuscular administrationrdquo

(Exhibit A-2)

I The Website Science pages also included a group of pages that began with a depiction of a DNA double helix and the title ldquoSCIENTIFIC EVIDENCErdquo These pages then described the ldquoFACTSrdquo about the Myers Cocktail including ldquopublished clinical researchrdquo and claimed that the Myers Cocktail ldquohas been found to be effectiverdquo against a variety of diseases and conditions including ldquofibromyalgiardquo and ldquocardiovascular diseaserdquo

(Exhibit A-14)

J The Scientific Evidence pages continued claiming

The author took over the care of [Dr] Myersrsquo patients using a modified version of his iV regimen in order to approximate the doses reported to be safe and effective for the treatment of cardiovascular disease [T]he modified Myersrsquo cocktail was helpful for a wide range of clinical conditions often producing dramatic results Conditions that frequently responded included fibromyalgia A small number of patients with congestive heart failure [and] angina were also treated with the Myersrsquo and most showed marked improvement This paper presents a rationale for the use of IV nutrient therapy reviews the relevant published clinical research describes personal clinical experiences

using the Myersrsquo and discusses potential side effects and precautions

(Exhibit A-14)

K The Scientific Evidence pages thereafter described purported clinical experiences of patients given a Myers Cocktail including case studies of patients with Fibromyalgia and Cardiovascular Disease (that used the same text as contained in the ldquoSuccess Storiesrdquo section of the Website discussed in Part 5C above) The Scientific Evidence pages ldquoConclusionrdquo section stated ldquoThe Myersrsquo has been found by the author and hundreds of other practitioners to be a safe and effective treatment for a wide range of clinical conditions In many instances this treatment is more effective and better tolerated than conventional medical therapiesrdquo (Exhibit A-17)

iV Bars Disclaimers

L At the bottom of almost all of the iV Bars Website pages Respondents included the

following statement in grayed-out difficult to read type ldquoFDA DISCLAIMER THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION THESE PRODUCTS ARE NOT INTENDED TO DIAGNOSE TREAT CURE OR PREVENT ANY DISEASErdquo

(See eg Exhibit A-1)

M A number of the iV Bars Website pages also contained the following statement

Disclaimer You should consult your physician before taking vitamins minerals nutritional supplements or herbal products Our vitamins and nutritional supplement products on this site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages may vary depending on personal requirements and availability Statements made here have not been evaluated by FDA

(Exhibit A-20 to 32)

iV Bars Safety Claims

N The iV Bars homepage stated ldquoIntravenous Vitamin Therapy [can be used] to both prevent and help treat a wide variety of conditions safely and effectivelyrdquo The Website homepage did not contain a disclaimer or disclosure related to this unqualified safety claim (Exhibit A-1)

O The Websitersquos Medical page and its Mobile page prominently claimed that Respondentsrsquo iV treatments are ldquoSafe for all agesrdquo and that they cause ldquoNo side effects or down timerdquo The websitersquos Medical page and its Mobile page did not contain disclaimers or disclosures related to these unqualified safety claims (Exhibit A-7 amp 10)

P Buried in the Websitersquos multiple Science pages was a disclosure that

Small risks are associated with the intravenous injection process which may include bruising around the injection site and are similar to the risks of having your blood drawn for lab tests Side Effects of treatment can include bruising around the site of the needle stick Some patients may have a tendency to vascular fragility and can suffer a phenomenon known as ldquoinfiltrationrdquo in which the walls of the vein rupture and the iV fluid leaks into the surrounding tissue causing local burning

(Exhibit A-11)

Q The Science pages also contained a lengthy discussion of ldquoSide Effects and

Precautionsrdquo for the Myers Cocktail that revealed a number of safety concerns including the following statements

Too rapid administration of magnesium can cause hypo-tension which can lead to light-headedness or even syncope [temporary loss of consciousness] The shift of potassium from the serum to the intracellular space can trigger hypokalemia [low level of potassium in the blood serum] The author has seen two patients develop severe muscle cramps several hours after receiving a Myersrsquo both patients had been taking medications known to deplete potassium Hypokalemia also increases the risk of digoxin-induced cardiac arrhythmias [One

patient] developed an arrhythmia which required short-term treatment in the intensive care unit

For elderly or frail individuals it may be advisable to start with lower doses[] [H]ypercalcemia can cause cardiac arrhythmias For that reason the author has tended to leave calcium out of the Myersrsquo when treating patients with cardiac disease Anaphylactic reactions to IV thiamine have been reported on rare occasions Only three such reactions have been identified in the US literature since 1946 However in the world literature a total of nine deaths attributed to thiamine administration were reported between 1965 and 1985

(Exhibit A-16 amp 17)

R The Science pagesrsquo ultimate ldquoConclusionrdquo stated ldquoThe Myersrsquo has been found by the author and hundreds of other practitioners to be a safe and effective treatment for a wide range of clinical conditionsrdquo (Exhibit A-17)

7 After arriving at iV Bars but before being given an iV treatment consumers are required to sign a two-page ldquoConsent and Authorization for Intravenous Therapy Proceduresrdquo form releasing Respondents from liability (ldquoRelease Formrdquo) An example of the Release Form is attached as Exhibit B This Release Form disclosed that there are ldquorisksrdquo and ldquopotentially dangerous side effectsrdquo involved with Respondentsrsquo iV treatments and contained the following statements among others

Risks I understand there is risk of mild diarrhea upset stomach nausea a feeling of pain and a warm sensation at the site of the injection a feeling or a sense of being swollen over the entire body headache and joint pain

Uncommon side effects are much more serious than the common side effects of Vitamin injections and such side effects should be reported to a physician to be evaluated for seriousness Uncommon and dangerous side effects include

bull Headache bull Nausea bull Diarrhea bull Bloating bull Constipation bull Indigestion or heartburn bull Abnormal bleeding bull Gastrointestinal hyperactivity bull Chest pain bull Flushed face bull Chills bull Fever bull upset stomach bull Kidney stones bull Fingernail weakening bull Hair loss bull Rapid heartbeat heart palpitations bull Restlessness bull Muscle cramps and weakness bull Dizziness I understand the possibility of having an allergic reaction to any of the ingredients found within the Vitamin injection is quite plausible If I experience any of these following signs of allergic reactions I should immediately consult my primary health care Physician and discontinue further use of the product Signs of allergic reactions include but [sic] not limited to bull Itching of skin bull Hives bull Rashes bull Wheezing bull Difficulty breathing bull Swelling of mouth or throat When medications are taken in conjunction with the Vitamin Injection drug interactions could occur These interactions can either increase your risk of bleeding or block the absorption of the Vitamins into the body

(Exhibit B-1 amp 2)

Falsity and Lack of Substantiation

8 Although Respondentsrsquo Website was replete with depictions of men and women dressed in

white lab coats looking through microscopes and Respondents claimed to operate an ldquoiV Bars Research Labrdquo with experienced biologists chemists pharmacists medical doctors naturopathic doctors and exercise physiologists no such iV Bars Research Lab exists In addition neither Respondents nor any third party commissioned by Respondents conducted clinical research tests or studies of the safety or efficacy of Respondentsrsquo iV Cocktails

9 There has been only one randomized and controlled human clinical trial of an iV Cocktail

advertised by Respondents That pilot study was of the Myers Cocktail given to patients with fibromyalgia Although the study found a strong placebo effect it found no statistically significant differences between subjects given the Myers Cocktail and those given a placebo in any outcome measure at 8 and 16 weeks (See Intravenous Micronutrient Therapy (Myersrsquo Cocktail) for Fibromyalgia A Placebo-Controlled Pilot Study Journal of Alternative and Complementary Medicine (March 2009))

10 The purported substantiation relied on by Respondents for their disease treatment claims consists of anecdotal stories of iV therapy patients and studies and articles regarding individual active ingredients given to animals or humans in significantly different doses formulations routes of administration or regimens than those advertised by Respondents

11 The safety risks and potential complications from Respondentsrsquo iV treatments include infection hypersensitivity and other allergic reactions drug interactions infiltration of iV fluid into the soft tissue outside the vain hematoma air embolism causing air to enter the vain blood clots phlebitis and cellulitis Potential side effects include diarrhea upset stomach nausea bloating constipation headache and joint pain In addition elderly consumers may be more susceptible to some of these risks and side effects Respondentsrsquo own Website and Release Forms acknowledge many of these risks and side effects

Count I False or Unsubstantiated Safety and Efficacy Claims

12 In connection with the advertising promotion offering for sale or sale of iV Cocktails

Respondents have represented directly or indirectly expressly or by implication that their iV Cocktails

A are an effective treatment for cancer B are an effective treatment for angina cardiovascular disease congestive heart failure

and myocardial infarction C are an effective treatment for multiple sclerosis D are an effective treatment for diabetes E are an effective treatment for fibromyalgia F are an effective treatment for neurodegenerative disorders G produce fast lasting results H are safe for all ages and I cause no side effects

13 The representations set forth in Paragraph 12 are false or misleading or were not

substantiated at the time the representations were made

Count II False Establishment Claims

Respondents have represented directly or indirectly expressly or by implication that Respondentsrsquo iV Cocktails are clinically or scientifically proven to

A treat cancer

B treat angina cardiovascular disease congestive heart failure and myocardial

infarction

C treat multiple sclerosis

D treat diabetes

E treat fibromyalgia

F treat neurodegenerative disorders and

G produce fast lasting results 15 In fact Respondentsrsquo iV Cocktails are not clinically or scientifically proven to

A treat cancer

infarction

D treat diabetes

G produce fast lasting results 16 Therefore the representations set forth in Paragraph 14 are false or misleading

Violations of Sections 5 and 12 17 The acts and practices of Respondents as alleged in this complaint constitute unfair or

deceptive acts or practices and the making of false advertisements in or affecting commerce in violation of Sections 5(a) and 12 of the Federal Trade Commission Act THEREFORE the Federal Trade Commission this _______ day of _______ 2018 has

issued this Complaint against Respondents By the Commission Donald S Clark Secretary SEAL

EXHIBIT A - 1

fshyz w fshyz 5 a_ a_ lt

An-tL ETIC MEDICAL HANGO VER AG E amp B EAUlY MOBIL E SCIENCE CONTACT - f middotM

tvl EDICA L iV lR EATMENl S SPOR TS RECOV ERY

ANXI ETY ATTACKS

NEUR OPATHY HYDRATI ON

W EDDING DISASTERS

FLU COLO RECOVERY

CA NCER

MIGRA INES

BELL S PALSY

HANGOVERS

AND MOR E

Yrtamins minenls and amino acids entw

your bloodstrean directty and immediately to help the body to bl-gin healing itseff

LEARN MORE ABOUT nE LAB

VISIT VITAMINDRIP

Since using N Bars I find I dont get down and out with the cold and flu_bull

Kellen Wi nslow Jr NFL Player

TAKING VITAMINS ORALLY IT SIMPLY DOES NOT WORK

BE EFFECTIVe ONLY 15 O F THE ACTNE NUTRIEN TS

CONSUMED ORALLY FIND THE IR WAY INTO

YOUR BLOODSTREAM

Our N Therapy delivers replenish ing fluids vitamins

mnel als amp amino acids into the bloodstream with 100

absorption where they are immed iately available for your

cells to use Res ulting in quicker recovery time and

improved over all performance

100 TRUE VITAMIN RETENTION

Developed by ii team of leading medical

doctors lilturopiithic doctors biochemists nutritiONsts and eercise- phys io logists

Our Success Stories

I am absolutely hooked on N Bars 1 am able to

keep up with my busy lifestyle_ bull

Kamila Orotle f Internation al Model

I READ MORE STORIES I

If you are new to the concept of Intravenous vitamin

Therapy yoo might be wondering why you re suddenly

hearTig so much about it Why is iibeing relied upon

by profes sional athletes to CEO s and most

importantly by patients suffering from a very seriou s

illness Intravenous Alamo T herapy represents an

exciting new paradig m in integrative and functional

medicine alkwoing us to both prevent and help treat a

wide variety of conditions safely and effectively im _m ___ _ ABOUT N BARS THE COMPANY

iV Bars profiting is ii technique employed

by o- medical staff to ~st In identifying

ii person s specific nutrient requirftllents

iVCTBARS DNA VitamiddotPanel

Your L i fe Just Better

pains have gone down dramabcaRy

Zenon Kono pka NHL player

EXHIBIT A - 2

An-tL ETIC MEDICAL HANGOVER AGE amp BEAUlY MOBIL E SCIENCE CONTACT - f middotM

~~~~i ~~~i~i~~ ~~i middot middot middot 100 UL TIMUM LEVELS ~--

THE CO ltPANY BEHIND THE BAG

INSPIR ATION

Inspired by the ear1y works of Dr Miers Aaron Keith fOIJlded wears in 2015 He assembled a wor1d class team of physicians biochemists and physiologists to create the formulas

and developed the unique marketing concept of N Bars In 2015 on June 1st W Bars was sold fOf the very first time in its home market Texas This was not only the launch of a

completely new product in fact it was the birth of a totally neN product category

V Bars Research Labs

Commitmbull nt

I bull L i ~ - -middot-

The applied Biology and Chemistry Group at iV Bars Labs is comprised of experienced bicgtk9Sts chemists pharmacists medical and naturopathic doctors and exercise

physiologists with two major responsibi lities

Provide subject matter expertise in the fields of chemistry molecular blology blotechnofogy rRCrobiology to help sotve problems foc on-going research

Develop proof-of -concept novel nutraceutical technologies to test and approve inject -able forrnJlatioos that are used in intravenous subcutaneous and intramuscu lar administration

EXHIBIT A - 3

1-z w 2 1-z 0 0 0 lt(

~ 0 0 ID

I CTOARS ATHLETIC MEDICAL HANGOVER AGE amp BEAUTY MOBILE SCIENCE v CONTACT v

A majority of ill patients have significant underlying nutritional deficiencies Food intolerances allergies and

sensiti vities can lead to gastro intestina l absorption problems Add itionally oral supplementation can be incomplete

or minimally absorbed The use of intravenous (N therapy has the abil ity to work instantaneously The followi ng are

case studies about different disorders and the effects that N therapy has had on these conditions

Case 1 M scle spasms

A 62 year-old female suffered from unexp lained leg cramps and muscle spasms for a period of more than two

years Blood work diagnost ic and imaging tests had been unremarkable Oral magnesium therapy and othe r

electro lyte therapy replacement provided little benefit The patient decided to proceed wi th a modified Myers

intravenous N) push After the first N push the patient was free of leg cramps and muscle spasms for a period of

approx imately t-vo months There were no adverse reactions or side effects reported

Case 2 middot Migraine headaches

A 58 year-o ld female suffers from daily frequent migraine headaches whi ch appeared to be triggered by

envi ronmenta l exposure to chemicals food and stress The headaches were occurring one to two times per week

Medications and other conservative measures have provided very little relief The patient started receiving

intravenous pushes with magnesium and other forms of b-vitam ins At the end of her initia l push the patient fe lt her

headache improving The patient received two more N pushes of the same formula over the next two weeks The

migra ine headaches are now occurring once every two w eeks compared to once or twice every week and w e

expect as her defic iency status improves they should become more infrequent

The benefits of N magnesium as a treatment for migraine headaches has been demonstrated in clinical trials In

one study pat ients with acute attack of migraine headache and low serum level of ionized magnesium were tested Of the 40 patients enrolled 35 patients had a reduction in pain of 50 or more 15 minutes after the infusion This

included nine patients who had comp lete relief ln 21 of these 35 pat ients the same degree of improvem ent or

complete relief lasted for 24 hours or more wi th a positive response

Case 3 Multiple Sclerosis

A 65 year -old male with progress ive multip le sclerosis presents to the clinic wheel chair bound The patient has tried

medications physical therap y and speech therap y However there have been little noticeable benefits with regards

to his leg strength end neurologicel function The petient reported no prob lems 11fth bowel or bledder control The

pat ient received an intravenous infusion of glutath ione After the first infusion he reported increased strengt h in his

legs His physical therapist and caretaker also reported noticing an improvement in his leg strength and ability to w alk After the second glutathione infusion the pat ient reported tha t the feeling in his hands has returned The

patient s increase in leg strength and hand sensa tion has continued wi thout any reported decline There w ere also

no reported adverse reactions

Case4 Diabetic peripheral neuropathy Restless leg syndrome

A 65 year-old male presents to the clin ic with a ten plus year history of rheumato id arthritis diabetes high blood

pressure neuropathy and restless leg syndrome The patient is taking blood pressure and anti -hypertensi ve

med ications His blood sugar and blood pressure is well mainta ined wi th his current medicat ion regimen However he continu es to have joint pain and leg pain The leg pain is worst at night and occas ionally wakes him up The

patient was started on intravenous vi tamin C and glutath ione therap y After the fourth treatment the patient s

restless symptoms and joint pain was completel y resolved The patient took a two-month break from therapy and

some of his leg symptoms returned Although the symptoms have returned they were not of the same intensity He

was re-started on vitamin C and glutathione therapy His symp toms started to improve after the first IV He is

currently on a maintenance protocol

Glutathione GSH) has a crucial role in cellular signaling and antioxidant defenses Glutathione is responsible for

the detoxification of reactive oxygen and nitrogen species and electroph iles produced by xenobiotics Adequate

levels of GSH are essent ial for the opt imal functioning of the immu ne system brain function regulation of energ y

production and mitochondrial su rvival A dep letion of GSH can lead to damage by oxidati ve stress increased levels

of pro- inflammatory mediators dysfunctions of intracel lular s ignaling netviorks decreased cell proliferation and DNA

synthesis

Gluta thione has been used to reduce toxicity of chemotherapeutic agents It has also been shown to improve pain

free walking distance in patients with periphera l obstructive arterial d isease reduce lipoperox idat ive damage in

early sept ic shock reverse some adverse effects of d iabetes (periphera l neuropathy ) improve anemia of patients

wi th chron ic renal failure and boost the immune system

Glutath ione has been well studied over the years The res even a YouTube video by Dr Oz discussing the

importance of glutathione and the role it plays in the treatment of d iabetes cancer aut ism and arthritis

Article By Dr Sana Eang ND

More Success Stories

Asthma

M=iitH

EXHIBIT A - 4

Case 1 A five-year-old boy presented with a two-year history of asthma During the previous 12 months he had

suffe red 20 asthma attacks severe enough to require a vis it to the hospital emergenc y department His symptoms

appeared to be exacerbat ed by several foods and skin tests had been pos itive for 23 of 26 inhalants tested His

initial treatment consisted of identification and avoidance of allergenic foods as w ell as daily oral supplementat ion

with pyridoxine (50 mg) vitam in C (1000 mg) calcium (200 mg) magnesium (100 mg) and pantothenic acid (100

mg) in two divided doses with meals On this regimen he experienced marked improvement and had no asthma

attacks requiring medical care until nearly 11 months after his initial visitAt that time the child now six years old

presented for an emergency visit with mild but pers istent wheezing and difficulty breathing He was given a slow IV

infusion containing 6 ml vitamin C 14 ml magnesium and 05 ml each of calcium 812 86 85 and 8 complex

The symptoms resolved within two minutes and did not recurOver the ensuing eight years and three months he

received a total of 63 IV treatments for acute exacerbat ions of asthma In most instances a sing le injection resu lted in marked improvement or complete relief within two minutes and the acute symptoms did not recur Occasiona lly

a second injection was needed after a period of 12 hours to two days and during one episode three treatments

were required over a four-day period As the patient grew the nutrient doses were graduall y increased by age 10

he was receiving 10 ml vitamin C 3 ml magnes ium 15 ml calcium and 1 ml each of 812 86 85 and 8

complex The treatment w as unsuccessful only once on that occasion the patient presented with generalized

urticaria angioedema and unusually severe asthma after the inadvertent ingestion of an artificial food coloring

(FDampC red 40 ) and other potential allergens Three separate injections given over a 60-m inute period produced

transient improvement each time However the symptoms returned and he was taken to the emergency room and

hospitalized Despite that single treatment failure the patient and his parents reported that IV nutrient therapy

worked faster produced a more sustained improvement and caused considerably fewer side effects than the

conventiona l therapies he had received previous ly in the emergency roomThe author has treated approx imate ly a

dozen asthmatics (main ly adu lts) wit h the Myers for acute asthma attacks in most instances marked improvement

or comp lete relief occurred within minutes A few patients received maintenance injections once weekly or every

other week during difficu lt times and reported the treatments kept their asthma under better controlIntravenous magnes ium is now well documented as an effective treatment for acute asthma In one study 38 patients wi th an

acute exacerbation of moderate-to-se vere asthma that had failed to respond to conventional beta- agonist therapy

were randomly assigned to receive in double-b lind fash ion IV infus ions of either magnes ium sulfate (12 g over a

20-minute period) or placebo (saline) 13 Peak expiratory flow rate improved to a sign ificantly greater extent in the

magnes ium group (225 to 297 Um in) than the placebo group (208 to 216 Umin) In addition the hospitalization rate

was significantly lower in the magnesium group than in the placebo group (37 vs 79 p lt 001) No patient had

a significant drop in blood pressure or change in heart rate after receiving magnesiumIn a second double-b lind

study 149 patients with acute asthma who were being treated with inhaled beta-agonists and IV steroids were

randomly assigned to receive an IV infusion of magnesium sulfate (2 g over 20 minutes) or saline placebo

beginning 30 minutes after presentation 14 Among patients with severe asthma (defined as forced expiratory

volume in 1 second [FEV1J less than 25 percent of predicted value) compared with placebo magnes ium

significantly reduced the hospital izat ion rate (333 vs 786 p lt 001) and significantly improved FEV1

However magnesium treatment was of no benefit to patients with moderate asthma (defined as baseline FEV1

between 25 and 75 percent of predicted value)ln two placebo-controlled studies of asthmat ic chi ldren iV

magnes ium sulfate significantly improved pulmonary function and significantly reduced hospitalization rates during

acute exacerbation s that had failed to respond to conventional therapy 1516 A dose of 40 mg per kg body weight

(maximum dose 2 g) given over a 20-m inute period appeared to be more effective than 25 mg per kg Higher doses

of N magnesium sulfate (10-20 g over 1 hour followed by 04 g per hour for 24 hours ) have been used successfull y

in the treatment of life-threatening status asthmatics In a few stud ies N magnes ium failed to improve pulmonary

function or to reduc e the need for hospitalization 17 18 How ever a metaana lysis of seven randomized trials

concluded that N magnesium reduc ed the need for hospitalization by 90 percent among patients with severe

asthma although the treatment was not beneficia l for patients with moderate asthma Calcium is the only other

component of the Myers that has been stud ied as a treatment for acute exacerbation s of asthma In an early

report a series of N infusions of ca lcium chloride rel ieved asthma symptoms in three consecutive patients with

relief occurring almost immediately after some injections20 Intravenous and IM administration of an unspecified

calcium salt temporaril y inhibited severe anaphy lactic reactions in two other patientsNutrients other than

magnes ium and calcium may have contributed to the beneficial effect obse rved in asthma patients Oral vitamins

C22 and 8623 24 and IM vitamin 81225 have each been used with some success against asthma although none of these nutrients has been tested as a treatment for acute attacks Intramuscu lar administrat ion of niacinamide has

been show n to reduce the severity of exper imenta lly induced asthma in guinea pigs 26 and pantothenic acid

appears to have an anti-allerg y effect in humans 27On one occasion a patients asthma attack was treated with N

magnes ium alone Although the symptoms reso lved rapidly they returned within 10-15 minutes The remaining

constituents of the Myers (without additional magnes ium) were then administered and the symptoms disappeared

almost immediate ly and did not return Thus it seems the Myers is more effective than magnesium alone in the

treatment of asthma attacks

Migraine

Case 2 A 44-year-old female suffered from frequent migraines which appeared to be triggered in many instances

by exposure to environmenta l chem icals or occasionally to ingestion of foods to which she was allergic Allergy

desens itization therapy had provided litt le benefit Over a six-year period the patient was given N therap y on

approximately 70 occasions for migraines Nearly all of these injections resu lted in considerable improvemen t or

complete relief with in several minutes although a few treatments were ineffective Through tria l and error it was

determ ined her most effective regimen was 16 ml vitam in C 5 ml magnes ium 4 ml calcium 2 ml 86 and 1 ml

each of 812 85 and 8 complex The 4-ml dose of calcium was found to provide better relief than lower calcium

dosesO ver the years a half dozen other patients have presented one or more li mes with an acute migraine In

almost every instance the Myers produced a gratifying response within a few minutesThe beneficial effect of N

magnes ium as a treatment for migraine has been demonst rated in recent clinical trials In one study 40 patients

with an acute migraine received 1 g magnes ium sulfate over a five -minute per iod28 Fifteen minutes after the

infusion 35 patients (875) reported at least a SO-percent reduct ion of pain and nine patients (225)

experienced complete relief In 21 of 35 patients who benefited the improvement pers isted for 24 hours or more Patients with an initially low serum ionized magnesium concentration (less than 054 mMolL) were significan tly

more l ikely to experience long- lasting improvement than were patients wi th initially higher serum ionized magnesium

levels In a single-blind trial that included 30 patients with an acute migraine N administrat ion of magnes ium sulfate

(1 g over 15 minutes) completely and permanent ly relieved pain in 13 of 15 patients (866) whereas no patients in

the placebo group became pain free (p lt 0001 for difference between groups )29 In additio n magnesium treatment

resulted in rapid disappearance of nausea vomiting and photophob ia in all 14 patients who had experienced those

symptomsA single 1-g dose of magnesium sulfate has also been reported to abort an episode of cluster headaches

in seven of 22 patients (32) and a se ries of three to five injection s provided sustained relief in an additional two patients (9) It is not clear whether the Myers is more effective than magnesium alone for migraines however

one patient did experience noticeable benefit from N calciu m

Fatigue

Many patients with unexplained fatigue have responded to the Myers wit h results lasting only a few days or as long lI~ ~P vPrllll mnnth~ PlllfiPnt~ whn hlnPfifpfI riftPn rPt11mirl lllf lhPir nwn tii~rrPtirin fnr lllnrithPr trPlllfmp nf whPn thP

EXHIBIT A - 5

effect had worn off One patient with fatigue associated with chronic hepatitis B experienced marked and

progressive improvement in energy levels with weekly or twice-month ly injectionsApproximately 10 patients with

chronic fatigue synd rome (CFS) received a minimum of four treatments (usually once w eekly for four weeks ) with

more than half showing clear improvement One patient experienced dramatic benefit after the first injection

whereas in other cases three or four injections were given before improvement was evident A few patients became

progressively healthier wi th continued injections and were eventua lly able to stop treatment Several others did not

overcom e their illness but periodic injections helped them function better There is some research support for the

use of parenteral magnesium in patients with fatigue One study found magnesium deficiency demonstrated by an N magnesium-load test in 47 percent of 93 patients with unexplained chronic fatigue including 50 with CFS In a

second study the mean erythrocyte magnesium concentration was significant ly lower in 20 patients with CFS than

in healthy controls One arm of the second study 32 patients with CFS were randomly assigned to receive in

double-b lind fashion 1 g magnesium sulfate IM or placebo once w eekly for six weeks Twelv e (80) of 15 patients

given magnesium reported improvement (eg more energy a better emotional state and less pain) and fatigue

was eliminated complete ly in seven cases In contrast only three (18) of 17 placebo-treated patients improved

(p=00015 for difference betyenteen groups) and in no case was the fatigue completely eliminated According to one

report at least half of CFS patients with magnesium deficiency benefited from oral magnesium supplementation

however some patients needed IM injections Other investigators using the IV magnes ium-load test found no

evidence of magnesium deficiency in patients with CFS and observed no improvement in symptoms following a

single infusion of magnesium sulfate (6 gin one hour)Vitamin 812 given IM has been reported to be helpful for

patients with unexplained fatigue 35 as w ell as those with CFS While the results obta ined with the Myers may be

attributab le in part to vitamin 812 many patients who responded to IV therapy obtained little or no benefit from IM

vitamin 812 alone

Fibromyalgia

Case 3 A 48-year-old woman presented with a six-year history of fair1y constant myalgias and arthra lgias with

pain in the neck back and hip and tightness in the left arm Six months previously she was found to have an

elevated sed imentation rate (50 mmhr) She was diagnosed by a rheumatologist as possibly having polymyalgia

rheumatic although the diagnosis of fibromyalgia was also cons idered Her history was also significant for

migra ines about eight times per year and chronic nasal congestion Physical examination revea led extremely st iff

muscles with decreased range of motion in many areas of her bodyThe patient was given a therapeutic trial

consist ing of 6 ml vitamin C 4 ml magnesium 25 ml calcium and 1 ml each of 8 12 86 85 and B complex At

the end of the inject ion she got off the table and with a look of amazemen t announced her muscle aches and joint pains w ere gone for the first time in six years This treatment was repeated after a week (at which time her

symptoms had not returned) follow ed by every other we ek for several months then once monthly for three years

Her initial regimen also included the identification and avoidance of allergen ic foods and treatment with low-dose

des iccated thyroid (eventually stab ilized at 60 mg per day) She discovered that eating refined sugar caused

myalgias and arthra lgias and that thyroid hormone improved her energy level mood and overall well being During

the three years of monthly maintenance injections she reported symptoms would begin to recur if she went much

longer than a month between treatments However they were never as severe as they w ere before she began

receiving N therapy The author has given the Myers to approximate ly 30 patients with fibromyalgia half have

experienced significant improvement in a few cases after the first injection but more often afte r three or four

treatmen tsThe beneficia l effect of parenteral nutrient therapy has been confirmed by one study published only as an abstract Eighty-six patients with chron ic muscular complaints including myofascial pain relapsing soft tissue

injuries and fibromyalgia rece ived 1M or N injections of magnesium either alone or in combination with calcium B

vitamins and vitamin C37 Improvement occurred in 74 percent of the patients of those 64 percent required four or

fewer injections for optimal results A minority of patients required long-term oral or parenteral magnesium to

maintain improv ement The positive response to parenteral magnesium is consistent w ith the observation that

nearly half of patients with fibromyalgia have intracellu lar magnesium deficiency despite having normal serum levels of the mineral38

Depression

Case 4 A 46-year-old man presented with a history of depression and anxiety since childhood He had been in

psychoanalysis for the past eight years A therapeutic trial with N nutrients was considered because the patient

reported that consumption of alcohol (known to deplete magnesium) aggravated his symptoms and because he

was taking a magnesium-depleting thiazide diuretic for hypertension He was initially given 1 ml each of

magnes ium 812 86 85 and B complex which resulted in a 70-80 percent reduction in his symptoms for one week A second injection produced a similar response that lasted two weeks Th rough trial and error it was

determined the most effect ive treatment was 5 ml magnes ium 3 ml B complex and 1 ml each of 8 12 86 and 85 The addition of calcium to the injection appea red to block some of the benefit Both oral and IM administration of

the same nutrien ts wer e tried but found to be ineffective Weekly injections provided almost complete relief from

symptoms and allowed him to discont inue psychotherapy The patient noted that rapidly administered injections

provided longer-lasting relief than did slower injectio ns The infusion rate was therefore carefully and progressi vely

increased without causing any adverse side effects or changes in blood pressure or heart rate The patient reported

that when the treatment was given over a one-minute period the effect would last approx imately two weeks

whereas a slower injection (such as five minutes) would last only a week Approx imately four years after initial

treatment he was able to reduce the frequency of injections to once month ly or lessMany other patients with

depress ion andor anxiety have shown a positive respon se to the Myers However this treatment should not be

considered first-line therapy for major depressionIt seems to be helpful only for certain subsets of depressed

individuals such as those who also suffer from fibromyalgia migraines excessive stress or alcohol-induced

exacerbations Shealy et al have observed an antidepressa nt effect of IV magnesium in some patients with chronic

pain 39

Cardiovascular Disease

Case 5 A 79-year-old man was seen at home in end-stage heart failure after having suffered four myocardial

infarctions During the previous 12 months spent mostly in the hospital he had become progressively worse his

ejection fraction had fallen to 19 percent and his body weight had declined from 171 pounds to a severely cachectic

113 pounds He was confined to bed and required supplementa l oxygen much of the time He also had severe

peripheral occ lusive arte rial disease which had resu lted in the development of gangrene of six toes A peripheral

angiogra m revealed complete occlusion of both femoralpopliteal arte ries with no detectable blood flow to the distal

ext remit ies Two independent vascular surgeons had recommended bilateral abovethe- knee amputat ions to

prevent developmen t of septice mia However the cardiologist advised the patient that his heart would not last more

than another month so the patient declined the amputations He was treated with weekly IM injections of

magnes ium sulfate (1 g) for eight weeks and prescribed oral supplementation Nith vitamins C and E B complex

folic acid and zinc The magnesium inject ions appeared to reduce the pain in his gangrenous toes considerably

with the benefit lasting about five days each time Six weeks after the first injection his eject ion fraction had

increased from 19 percent to 36 percent and he no longer requiredsuppemental oxygen After eight w eeks the IM

injections were replaced by week ly IV injections consisting of 5 ml magnesium 1 ml each of 812 86 85 and B

complex and a low-dose (02 ml ) trace mineral preparation (MTE-5 containing zinc copper chromium selenium

EXHIBIT A - 6

and manganese) After a tota l of 18 months his weight had increased from 113 to 147 pounds wh ich was

remarkable as cardiac cachexia is generally considered to be irreversible In addition the gangrenous areas on his

toes had sloughed and been replaced almost entirely by healthy tissue Intravenous therapy was continued and

eventually reduced to every other week The patient lived for eight years and died at age 87 from multiple organ failureOf the handful of other patients wi th angina or heart failure who received IV or IM injections of magnesium

(with or without B vitamins) all showed significant improvement The results with angina are consistent with those

reported by others using parenteral magnes ium therapy 40-42

Upper Respiratory T-act Infections

Case 6 A 40-year-old male presented with a cold and a one-day history of fatigue nasal congest ion and

rhinorrhea He was given an N infusion of 16 ml vitamin C 3 ml magnes ium 15 ml calcium and 1 ml each of

812 86 85 and B complex By the end of the 10-minute treatment he was symptom free The cold symptoms did

return the next day but were only 10 percent as severe as before the inject ionOne-quarter to one-third of patients

who received the Myers for an acute respiratory infection experienced marked improvement either immediately or

by the next morning Approximately half of patients given this treatment reported that it shortened the duration of

their illness Patients who benefited tended to have a similar response if treated for a subsequent infection whereas

non-responders tended to remain non-responders

Case 7 A 32-year-old female had a long history of chronic sinusitis Avoidance of allergen ic foods and oral

supplementat ion with vit amin C and other nutrients had provided on ly minimal benefit She w as given an N infusion

of 20 ml vitam in C 4 ml magnesium 2 ml calcium and 1 ml each of 812 B6 85 and B complex this protocol

was repeated the next day At the time these injections w ere given she had been experiencing persistent sinus

problems for a year Her symptoms resolved rapidly after the injections and she remained relatively symptom free for more than six months The same treatment given at a later date was also helpfu l although the benefit was not

as pronounced as the first timeOne other patient with chronic sinusitis had a sim ilar response to back-to-back injections while a few others show ed no improvement

Seasonal A ergic Rhinitis

Case 8 A 38-year-old man had a long history of seasonal allergic rhinitis occurring each spring and lasting about

a month Symptoms included nasal congestion itchy eyes and fatigueDuring a symptomatic period an fl infusion

of 12 ml vitam in C 3 ml magnesium and 1 ml each of 8 12 B6 85 and B complex provided rapid relief This

treatment was repeated as needed during the hay fever season (once weekly or less) and successfull y contro lled

his symptoms In subsequent years he began the N s shortly before and repeated them periodically during the hay

fever season this approach prevented the development of symptoms

Narcotic Withdrawal

Case 9 A 35-year-old man addicted to morphine came to the office in the early stages of withd rawal with

diaphoresis and extreme agitation He was given an N infusion of 16 ml vitamin C 5 ml magnesium 25 ml

calc ium and 1 ml each of 8 12 86 85 and 8 comp lex In his agitated state he was unable to sit st ill on the exam

table so we walked up and down the hall with a butterfly needle in his arm Halfway through the inject ion he was able to sit still and by the end of the injection his withdr awal symptoms were al leviated The symptoms returned 36

hours later he therefore came for another treatment which aga in relieved the symptoms within minutes He returned the next day still symptom free for a third injection which carried him uneventfully through the remainder

of the withdrawal period

Chronic Urticaria

Case 10 A 71-year-old w oman had chron ic urticaria wit h hives present somewhere on her body nearly every day

for 10 years An allergy-eliminat ion diet and oral supplementat ion with vitamin C and other nutrients provided little or

no relief She was given an iV infusion of 12ml vitamin C 3 ml magnesium 15 ml calcium and 1 ml each of

812 86 85 and B complex The same treatment was repeated the following day After these injections the hives

resolved rapidly and did not recur for more than a year When the les ions did recur the IV treatment was repeated

but was ineffect ive

Athletic Performance

Case 11 An 18-year-old 235-pound high school wrestler developed a flu-like illness four days before a major

tournament Two days before the three-day tournament when it appeared he might have to miss the event he was

given an N injection of 16 ml vitamin C 5 ml magnesium 25 ml calcium and 1 ml each of 812 86 85 and B

complex The next morning he remarked that he had more energy than he had ever had in his life This energy

boost persisted for the duration of the tournament at which he took second place a better performance than at any

other time in his careerIn this era in whic h many athletes are using performance-enhancing drugs it is not the authors intent ion to encourage athletes to seek another ~boost with iV nutrients However this case does

demonstrate that nutritional factors can play an important role in athletic performance

Hyperthyroidism

Two patients wi th hyperthyroidism were treated with the Myers once or 1-vice weekly for several weeks In one

case the treatment controlled the symptoms of hyperthyroidism although the re was no reduction in thyroidshy

hormone levels The injections were discont inued afte r medical therapy had restored the hormone levels to normal

In the other case symptoms improved markedly after the first injection and thyro id-function tests measured tv-to

weeks later returned to normalThe potential value of N nutrient therapy for patients with hyperthyroid ism is

supported by several studies Serum and erythrocyte magnesium levels have been found to be low in patients with Graves disease43 In addit ion daity IM injections of magnesium chloride (20 ml of a 14-percent solut ion) for 3-7

weeks reduced the size of the thyroid gland and improved the clin ical condit ion of three patients with

hyperthyroidism 44 Intravenous vitamin 86 (50 mg per day) was reported to relieve muscle weakness in three

patients with hyperthyroidi sm45 and animal studies indicate vitami n 812 can counteract some of the adverse effects of experimentally induced hyperthyroidism

EXHIBIT A - 7

ATHLETIC HANGOVER AG EampBEAUTY MOBIL E SCIENCE CONCT - f middotmiddotM

Why Drip The maority of us are ITT a constant state of toxicity malnutrition and dehyd rabon - and we don t even know It We re exposed to envirorrnerital toxins oo a daily basis Diets heavy

in nutrient-sparse foods rob us of vital vitamins and damaged digestive systems prevent us from property absorbing the nutrients we do eat Busy lifestyles stress and illness

further deple te our suppty setting us up fOf chronic cooditions and disease And w e never truly drink enough fluids which is why dehydraboo is the 1 cause of ag ing and fatigue and

a leading cause of disea se

Even the healthiest bodies are only able to absorb about 50 of the vitarnns and hydration taken orally through foltXl drink and supplements But IV drips bypass the gut delivering

essenbal nutnents and fluids di rectly mto the bloodstream for qutck and easy 100 absorption at high doses that woukI never be tolerated Ofally This alows us to detoxify nounsh

and rehyd rate ou r eels from the inside out fOf dramatic long -lasttog and often nstant results

Benefits

100 absorption High doses not tolerated oralty

Safe amp painless Fast lasting results

No side effects or down time No preservattves or additives

Safe for all ages Most take only 30-45 min

Medically-SUpeViSed facility Allowed by all major athelle

associations

Adrenal fatigue Cancer Asthma

COkls amp nu Celiac disease

Gluten sensrbv1ty Chronic fatigue syndrome

Chronic pain Congestive heart failure

Dehydraoon

Depression amp anxiety

Conditions

Diabetes Effects of Aging

lnfertlhty amp pregnancy Flhromyalgia

Gast rointestinal cond1b0ns General wellness

Hangove rs Heavy metal toxicity High blood pressure

Immune health

Aids m Weight Loss

lnJUfleS Low energy

POOfmemory Migraine amp tens ion headaches Neurodegenerative disorders

Nutnent deficiencies Post surgical healing

Preventative care Skin conditions

Stress

Revitalize hair amp nails

RECHARGE REPAIR

EXHIBIT A - 8

A n-tL ETIC MEDICAL bull AGE amp BEAUlY MOBILE SC IEN C E CONTACT - f middotM

Minor Urgent Care services for minor illnesses

such as

Sorenoats Urinary Tract Infections

Yeast Infections Kidney Stones

Sinus Infections Erectie Oysfirc tions

For severe ~tnesses please consult y~ primaty

phy sician or call 911 for emergencies

Hangovers are caused by 4 different iss ues

Inflammation from Acetaldehyde

Toxicity

Hmgo ver Symptoms

Dehydration Glutamme

Rebound Acute Akohol

Withdraw

Hangover symptoms are well known and include headache weakness and general discomfort that can occirfrom

excessrve alcohol intake and dehydration

Al iVBars we can provide you with IV hydration wtwch can irxlude fluids and vrtamms wtuch may help in your

hangover rec ovefj

Hango ver Pre vent ion

Alcohol causes dehydration because it inhibits a hormone called anti---Oiuretic homlone (ADH ) This hormone has a

constant level ri the body and keeps you from urinaung out an of the water in your body When you drink alcohol the level of thts hormone becomes low and you urinate more vVhile lhis happens you are also losing salt One

alcoholic drink can result in up to a pint of unne production This elect becomes less as you dnnk more _ But If you

dnn k 15 drinks In a night you can end up well over two liters dehydrated

Dehydratioo causes nausea headache and dizziness just by itself lnflanvnatlOll makes this everi worse It is like

a double w harrrny_ As a person gets older the effects are mor e significant as it takes kgtngef for the body to

rehydrate and get rid of the inflammation

What can you do abou t a hango ver

1_ Everi though dehydration is ooty one component of a hangover uy to drinllt 8 oz of water after eNery two or ltYee

drinks Also uy to eat some bar food Most bar food is salty_ You need to replenish the salt you lose as the

electrolytes are important

2 Also uy to dnnk at least somewhat responsibly If you are in for a long weekend of party ing uy to pace y01JSelf

Schedule fOf a fl Bars package with vitamins and anooxidants hen you drink alcohol you use up yrur stores of

vitamins and antioxidants which help process the alcohol and inflarrmatioo out ofyOlK body

3 Drink high-end clear akohol High quality vodka gin and clear 1equila have kIWer levels of llllpllrittes Thes e

impuribes lead to more acetaldehyde and simlar substances These are what cause inflammation wl-ch is the key

component of a hangover

4_ Eat a decent meal before you go out Meat contains many arrunoactds and 8 vitamins which are necessary for

processing alcohol Food also delays the absorption of alcohol So hit one of the many great Daftas feeding spots

before a night out on the town

All the IV fluids in the wol1d wil not sotve a Level A Rager hangover without other medjcations and supplemental

treatments

Our facility is staffed with EMTs Physician Assistants and Registered Nurses to make sure you are professlOllally eNaluated and treated

W e do not take insu rance We are able to provide you with a bill lhat you may file with you insixance company

Wbull stro ng ly encourage you to pre-book your appointment as treatment slo t s cJn be limited on th e week e nds

Use our convenient onl iM boot 09 system to res erve yo u r spot today

EXHIBIT A - 9

A n-tL ETIC MEDICAL HANGOVER MOBILE SCIENC E CONTACT - f middotM

essenbal nutnents and fluids d irectly mto the bloodstream for qutck and easy 100 absorption at high doses that woukI never be tolerated Ofally This alows us to detoxify nounsh

Mood Support Aches amp Pains Diet amp Detox Immune Support

Mood Support is a functional IV Aches and Pains provides Diet and Detox provides Immune Support es a funct10nal lnjecbon that replemsh1ng fluids vItamms replemshmg fluids Vitamins V lnJect10n proVKling

pmv1des replemsh1ng fluids minerals and ammo acids at a minerals amp ammo acids to burn replemshmg fluids v1tamIns Vlli1111111gt 111i11e1i1IS iIIKl i11111110 te11uli1J level 1edoci11y sulJtJom lJtxly fi11 lleloxify your m111e1i1b mKl t11111io lit ttb lo

acids to boost the bodys natural inflammation while increasing body to net rt of unhealthy toxins combat cold and flu symptoms serotomn levels and hep circulation amp boost energy_ and get you back to lfe promote total calmness

Effective In relieving aches Boost metabolism amp energy Cold and flu symptoms Ideal for when your feelmg under amp pains associated with back detoxify your Vital organs seasonal allergies reduce stress anXJOus or exhausted to amp muscles headaches teeth eliminate excess body fat ox1datJve stress protect against

relax muscles chill rest restOfe menstrual cramps rheumatic reduce hunger cravmgs fit mto free radicals boost immune improve mood and much more amp much more those Jeans amp much more system amp much more

RECHARGE REPAIR

EXHIBIT A - 10

An-tL ETIC MEDICAL HANGOV ER AGE amp BEAUlY SCIENCE CONTACT - f middotM

We Are Mobile We Come To You N Bars has a full serv ice mobile vehicle that allows us to deliver our RN Of EMT to you whether for personal needs a special rught out Of arryttng you desire Our licensed medical

stalfwill come right to yOUf doof lo deliver the treatment of your needs AI1y and all parncipants requesting WCocktails must pre-registerwrth OU sister-stte _ wwwVJtanwldnpca

priolt lo your special night eventdeg pefSonal occasion Al cocktails are available for ou- mobile service with an addibooal $150 travel fee Travel fee may be waived if 3 or more

cocktails are pure hased fCN the event

Benefits

100deg4 absorpt10n High doses not tolerated orally

Safe amp painless l=ast lastmg results

No side effectsdeg down time No preservatJves or additives

Medically-supecvised facillty Allowed by all major athletic

assoctat1ons

Cokb amp flu

Celiac disease Gluten sensitivity

Chronic fabgue syndrome Chrome pain

Congestive heart failure Dehydralfon

Depress10n amp anxiety

Conditions

lnfertlhty amp pregnancy l=ibromyilgii

Gastroinleslinal conditlons General wellness

Hangovers Heavy metal toxicity High blood pressure

Immune health Aids m W01ght Loss

lnJunes Low energy

Poor memory Migminc amp tcfl 1on headachegt

Neurodegenerative disorders Nutrient deficiencies Post surgical healing

Stress Revitalize hair amp nails

EXHIBIT A - 11

ATHLETIC MEDICAL HANG OVER AG EampBEAUTY MOBILE CONCT - f middotmiddotM

THE SCIENCE BEH IND iV Bars

KNOWLEDGE

DID OU NOW iV Bars IS MUCH lORE EFFECT E THAN TA NG TA~ INS ORALL

Taking vitamin supplements is certainly beneficial Howeva few people realize that when you sw allow a vnamm piU Of a multi-vitamin the bodys natural absorptJOfl process CiYI

render upto 85 of that vitarrin useless_ In other words when you ingest vitarrins by mouth only 15 of lhe active nutrients may eventually find their wry into your bloodsream

When you receive an bullw-the nutrients enter yOUI bloodstream dleclly and immediately to help the body 10 begin hea~ng itself_ You get much higher concentrations of nutrients

delivered directly to you r body s cells through intravenous therapy thus allowing your body to better abs orb and utilize these nutrients

INTRAVENOUS (i THERAPY

Intravenous iV) Therapy ot Intravenous Micronutrient Therapy (Ml1T) rs a treatment

method which uses nutrients such as vitamins Of mtnerals and administers these

directly into the bloodstre am typically through a vein in the am1 more specificaly the

crook of the arm There are several advantages of giving the body nutrieflts by the intrashy

venous method First by iniecting substances directly into the bloodstr eam you

eliminate any alteration in the nutnents wtvch may occur from the actions of digestive enzymes Second the amount of nutneots in the blood can reach much higher more

therapeutic levels faster than ts possible bf absorbing nutnents through the Gastroshy

lntestinal system Tivs may be particul arly Wfl)Ortant if a patient is suffemg from a GI

system dtsorder where absorptlOrl of nutnents is l)aired In some cases the Nuse of

micro-ootlients perrnts much higher levels than are possible even with a healthy GI

system

HAT CAN T BE USED FOR

The vitamins and rrinerals used in NMT are co-factors in biochemical reactions in every

cell in our bodies As a result NMT can be used as an adjunct in any cond ition where

lovr levels of nutrients or other nutritional deficiencies are suspected Immune Support

Anti Aging Athletic Performance Alefgies Depression Hormone Balance Migraines

Ch ronic Fatigue Inflammatory GI conditions Fibrorrryalgia and many others all respond

to iMT for many patienls

S T SAFE

The stbslances used in iVMT are vitamins and minerals which are categorized as

Essentia l Nutrients middot - those things our bodies must have in order 10 be healthy or even

s urvive but are incapable of making from other raN materials Traditionall Essential

Nutrients were obtained from the food we eat In modem times however the poor

quality of our over -proce~~ed foocb means that ~t of 1r1-are ~eve rely de ficient in

these Essential Nutnerits Deficiencies of these nutnents in fact are assoc iated with

most chronic ilnesses Providing the body with Essential Nutrients it badly needs is

generallf healthy for most people Sma ll risks are associated with the intrav enous

injecnon process wtwh may include bruising around he iljection site and are similar to

the risks of having yOUf blood drawn for lab lests Side Elects of treatment can include

bruising around the site of the needle stick Some patients may have a tendency to

v ascuar fragility and can suffer a phenomenon known as infiltration in which the walls

of the vein rupture and the N fluid leaks into the surrounding tissue causing local

burning This wilt dissipate within a short period of time bu the N site wil need 10 be

moved 10 anomer vem Some pauents may have sma ll Of hard -tofind veins In rare

instances if you have smal veins Of are especialy prone to vascular fragility you may

not be a candidate for iVMT In some instances a period of high dose oral nutrients can

build up your nutritional state and help strengthen you r VetnS to the point you can use

the iVMT therapy

middot1 Bars PROFILING PROCESS

Although 999 of human DNA is the same in every person enough of the DNA is

unique to distinguis h one person from anoher Male or female short or tal thin or

muscular low or high activity level world class athlete or weekend warrior peopk are

al unique and so are their nUIJlent requirements Developed by a team of leading

medical doctors naturopathic doctors btochemists nutritionists and exercise

physiologis ts N Bars profi ling is a technique employed t1f our medica l practitioners 10

Msit in identifying a per5ons specific nutrient requifement5 iV Ba~ profib arc

encrypted sets of nurrtgters that reflect a persons cooent state of hea lth wh tch are used

as the person s nutrient ldentrlierThe process begins with he selection of a therapy

follovred by a senes of medical health and lifestyle questions The data from these

questions will automatJca lly be run through the iVBars propnetary software program

which wil produce your profile

Bars PROFILE

Your profile includes a health report whic h reflects your current state of health and a

recommended N formtAa wtich addresses you r specific nutrient requi rements You may

also choose to be contacted bf one of our medical practitioners to review your report or

book an appointment to visit a N Bars clinic near you

EXHIBIT A - 12

ATHLETIC MEDICAL HANGOV ER AG E amp BEAUTY MOBILE CONCT - f middotmiddotM

ARE YOU GETTING THE NUTRIENTS YOU NEED

WHY IS IUTRIElJT STATUS SO IMPORTANT

Overwhelmtng scientific evidence confi rms that vitamin deficiencies are associated with

disease processes and the overaU coodltlon of ones health Vitamin rrwtefal and

antioxidant deficiencies has been shown to suppress irrvnuoe function and contnbute to

ch rome degener ative processes such as arthritis cancer Alzheimer s ca rdiovascular

disease and diabetes This body of research has been reaf 1rmed by the ournal of the

Amencan Medic al Association (June 19 2002 -Vol 287 No23)

But I eat a balanced diet exercise and take a multivitamin

Nutrient defic iencies are common

University research shows that 90 of people are def1c1ent and 50 of those people are already taking

a mulhv1tamm

F THIS DESCRIBES ALL OR PART OF OUR LIFESTYLE READ ON Many people lead healthy ffestyles yet some individuals still have deficiencies But Why

ABSORPTION

Although you may eat a balanced diet if you do not absorb vitamins minerals antioxidants andor other essential micronutrients property you can hav e deficiencies

LIFEST LE

Ex cessive physical activity pres cription drugs smok ing alcohol and sedentary habits all impact micronutrient demands

CHROI IC ILLNESS

Health conditions such as arthritis cancer ca rdiovascular disease diabetes fatigue and multiple sclerosis to name a few ca n be affected directly or 1ncfirectly by ITWromrtnent

deficiencies

O ur n-ronutnent requirements at age 30 are qurte different from our req111rements at age 40 50 and beyond Absorption difficulties especially of vitamin 812 quite corrmonly occur

as we age

BIOCHE CAL NDIVIDUALIT Because each of us IS metabolically and blochefllcally Ulllque the m1tronutrien1 requirements for one person may be quite differenl than the requr-ements of another

EXHIBIT A - 13

Nutrition is at the core of integrative health and iV Bars Micronutrient Testing is the most advanced diagnostic tool ava lable

Micronutrienl testing measures how micronutrients are actually functiorwig wittvn your white blood cells These tests allow nutritional assessmen t for a broad variety of clinical

conditions general wellness and the prevention of chronic diseases including iYttuitis cancer card iovas cular risk diabetes vanous immunological disorders and metabolic

disorders

Micronutrient Testing gives a functiona l cellula r analysi s of nutnent deficiencies and provides a 4-6 month windcM of nutritional history FOf those people liv ing in Dallas or Addison

or testing might be able to provide infOfmatlon to best optnize your vitamin supplementation

TEST COMPONEN TS

1ITAIIINS

VI TAMIN A VITAMIN 81 VITAMIN 82 VITAMIN B3 VITAMIN 86 VITAMIN 812 VITAMIN C VI TAMIN D VITAMIN K BIO TIN FOLATE PANTOTHENA TE

INERALS

CALCIUM MAGN ESIUM Z INC COPP ER MANGANESE

At NOACIDS

AS~GINE GLUTAMlNE SERINE

FATTY ACIDS

OLEICACID

~ETABOLTES

CHOLINE INOSITO L CARNITINE

ANTIOXIDANTS

GLUTATHIONE SELENIUM VITAMIN E ALPHA UPOIC ACID COENZYME 010 CYSTEINE

CARBOHYDRATE METABOLIS

CHROMIUM FRUCTOSE SENSITMTY GLUCOSE -INSULIN METABOLISM

Talk to a bullV Barsreg doctor today aoout Micronutnent Testing

to determine your nutritiona stat 1s

BOOK APPOINTMENT NOW

EXHIBIT A - 14

ATHL ETIC MEDICAL HANG OVER AG EampBEAUTY MOBILE CONCT - f middotmiddotM

lntraveno11s lI 1trient Therapy bull The Mvers Cocktail

By Alin R Gaby MD

SCIENTIFIC EVIDENCE

Building oo lhe work of the late John Myers MD the author has used an 111travenous vitamin-and -mineral formula fof the treatment of a wide range of clinical conditions The modified

Myers cocktail which consists of magnesJUm calcium B vitamns and vita nwl C has beefl found to be elective against acute asthma attacks migraines fatigue (including

ch ronic fatigue syndrome) fibromyalgia acute muscle spasm upper resptrat ory tract infections chroruc sinusitis seasonal allergic rhinitis cardiovascular disease and other

disorders_ Tots papef presents a rationale for reviews the relevant pubished clncal research describes the authors c linical expenences and discusses potenbal side effects and

precautions (Ahemabve Medical Review 20027(5)389-403)

Introduction

John Myers MD a physician from Balt imo-e Maryland pioneered the use of intravenous (iV) vitamins and mine rals as part of the ov era ll treatmeflt of various medical problems The

author never met Dr _ Myers despne living n Baltimofe but had hear d of his work and had occasionally used N nutrients to treat fatigue or acute infections After Dr_ Myers died m

1984 a number of his patients sought nutnert irljeCtJonS from the author Some of them had been receiving infections monttvy weekly or tw ice weekly for many years - 25 years or

more in a few cases _ C hronic problems such as fatigue depresslOll chest pain or palpitations were well controlled by these treatments hoYrever the problems would recur if the

patients went too long without an i~lionlt was not clear exac tty what the Myers cocktai r consisted of as the information provided by patients was incomplete and no published or

written mateoal on the treatmerlt was available It appeared that Myers used a 10ml synnge and administered by slow N push a combination of magnesium chloride caJcium

gluconate thiamine vitamin 86 vitamin B12 calcium pantothenate vitamn B complex vitamin C and dilute hydrochloric acid The exact doses ofindFVidual components were

unknown but Myers apparently used a two-percent solution of magnesMTI chlonde rather than the more widely available preparations containing 20--percent magneslUOI chloride deg 50--percent magnesUll sulfate The author took over the care of Myers patients using a modified version of his N regimeri Most notably the magnesium dose was increased by

appmx1111atety 10fold by using 20percent magnes 1Um chloride 1n order to approx imate the doses reported to be safe and efectrve for the treatment of cardiovascular disease 1 2 ln

addition the hydrochlonc acid was efiminaled and the vitamin C was increased particularfy fOf problems related to allergy or infeclloo Folic acid was not included as It tends to form

a precipitate when mxed with other nutnents Thts treatment was suggested for other patients and it soon became apparent that the modified Myers cockta il (here after referred to as

bullthe Myers ) was helpful for a wide range of clinical condillons often producing dramabc results Over an 11-year perlOd approximately 15000 ~lions were admirnstered 1n an

outpatient settwig to an estimated 800-1000 different patients Conditions that frequently responded included asthma attacks acute migraines fatigue (IOCluding chrorw fatigue

syndrome) fibromyalgia acute muscle spasm upper respiratory tract infections chrome sinusitis and seasonal allergic rhrwtts A small number of patients with congestive heart

failure angina chronic urticaria hyperthyrCldism dysmenorrhea or other conCJtioos were also treated with the Myers and rrost showed marked improvement Many relatively healthy patients chose to receive periodic tjections because it enhanced their overal well beig for periods of a week to several rTIOfllhs D uring the past 16 years these clinical results have been presented at more than 20 medica l conferences to several thousand physicians Today many doctors (probably more than 1000 in the United States ) use the

Myers_ Some have made fmher modifications accOfding to their own preferences In queryWlg audiences from the lectern and from informal discussions with colleagues at

conferences the author has yet to encounter a practitionet- whose experience with this treatment has differed significantly from his ownDespite the many positive anecdotal reports

there is only a small amount of published research supporting the use of this treatment There is one uncontroied trial in which the My ers was beneficial in the treatment of

musculoskeletal pain syndromes including fibromyalgia_ Intravenous magnesium alone has been reported mainly in open trials to be elfective agamst angina acute rTigraines

clus1er headaches depresslOll and chrOfllC pain _ In recent y ears double-blind trials have shown IV magnesium can rapidly abort acute asthma attacks There are also several

published case reports in which IV calcium provided rapid relief from asthma or anaphylactic reactions This paper presents a rationale for the use of IV nutrient therapy reviews the

relevan t pubished clinical research describes personal clinical experiences using the Myers and discusses potential side effects and prec autions

Theoretical Basis For 1V Therapy

Intravenous administration of nutrients can achieve serum concentr ations not obtainable with oral deg even intramuscular (IM) administration For example as the oral dose of

vitamin C is increased progressively the serum concentration ot ascorbatetends to approach an upper limit as a result of both saturation of gastrointestinal absorption and a sharp

increase in renal clearance of the vitamin 3 When the daily intake of vitamin C is increased 12-fold from 200 mgday to 2 500 mgday the plasma concentr ation increases by only 25

percent from 1 2 to 15 mgdl The highest serum vrtarr111 C level reported after oral admmistrallon of pharmacological doses o f the vitartlfl is 93 mgdL In contrast N admir-stratlOll of 50gdJy ofvrtamm C resuted in a mean peak ptasma level of 80 mgdl4 S1rrilarty ora l supplementation wrth magnesium results in tittle or no change 1n serum

magnesium concentrations whereas IV admirnstrabon can double or tn~ the serum levels 5 6 at least for a short perlOd of tuneVanous nutnents have been shown to exert

pharmacological effects which are Wl man cases dependent Ofl the concentration of the nutrient FOfexample an antiviral effect of vitamin Chas been demoostrated at a

concentration of 10-15 mgdl 4 a level adeYable with IV but not oral therapy Al a concentranon of 88 mgdl 1n vitro vitalTWI C destroyed 72 percent of the hrstamine present in the

mediUTI7 Lower concentrations were not tested but it is possible the serum levels of vitamin C attainable by giving several g rams in an IV push would produce an antnistaITVOe

effect in vFVo_ Such an effect would have implications for the treatment of various allergic condioonsMagnesun ions promote relaxation of both vascular8 and bronchial9 smooth

muscle- elfects that might be useful in the acute treatmentofvasospasbC angna and bronct-ial asthma respectivety_ It is likety these and other nutrients exert additional as yet

unidentified pharmacological effects when present in high concentrationsIn addition to having direct pharmacological effects IV rnruient thefapy may be more effective than oral or

IM treatment for correcting intraceDutar nutrient deficits Some nutrients are present at much higher concentrations in the cells than in the serum For example the average

magnesium concentration in myocard ial eels is 1D tlmes higher than the extracellular concentration Toes ratio is malrtta ined in healthy cells by an active-transport system that

cOfltinually ptn1p5 magnesium ions into cells against the concentration gradient In certain disease states the capacity of membrane pumps to maintain normal concentration

gradients may be compromised In one study the mean myocanfia magnesium concentra t ion was 65--percent loYer 1n patients with cardiomyopathy than in healthy controls 10

implying 3 reduction in the intracellubr to extmcellubr r31io to ~s th3n 1 to 1 s m39nesium pbys 3 key role in mitochondrill energy Pfoduction intracellullf magnesium deficiency

may exacerbate heart failure and lead to a VICIOUS cycle of further intracellular magoeslUfTl loss and more severe heart failureIntravenous admI01Strat1011 of magnesium by producing

a marked though transient wicrease in the serum concentration provides a window of opporturnty for aiing cells to take up magnesrum against a smaller concentration gradient

Nutrients taken up by cells after an N infus iofl may eventually leak out again but perhaps some healing takes place before they do If eels are repeatedly flooded with nutnents the

improvement may be cumulative It has been the authors observation that some patients who receive a series of N injections become progressFVety healthier In these patients the

interval between treatments can be gradually increased and eventually the injections are no longer necessaryOther patients require regular injecnons for an indefinite period of time

in order to control their medical probtems This dependence on N inections could cooceivably result from any of the following (1) a genetica lly determined imj)arment in the capacity

to mainta in norma l intracellular nutrient concentrations 11 (2) an inborn error of metaoolism that can be controlled onty by maintaining a higher than normal concentr ation of a

particular nutrient or (3) a renal leak of a nutrient 12 In some cases continued Ntheravt may be necessary because a disease state is too advanced to be reversible

The odiied eAyers Cockta1

See Table 1 for the nutrients that make up the modified Myers cockt ail Dexpanthenol is the commercially available injectable form of pantothenic acid (vitamin 85) One mtmliter of B

complex 100 contains 100 mg each of thiamine and niacinamide and 2 mg each of riboftavin dexpanthenol and pyridoxine

Nut11ents 1n the Myltgtrs Cocl1ail

Magnesium chloride hexahydra te 20 (magnesiool)

Calcium gluconate 10 (calcium)

Hydroxocobalarrnn 1 000 rocgml (8 12)

Pyridoxine hydrochloride 100mgmL (86 )

Oe xpanthenol 250 mgml (85)8 c~x 100 (B complex)

Alamin C 222 mgml (C)

Al l ingredients are drawn into one syringe and 8-20 ml of sterile water (oc cas lOM ly more) is added to reduce the hypertonicity of the solution After gently mixing by turning the

syringe a few times the solution is administered sloYly usually over a period of 5-15 minutes (depending on the doses of minerals used and on individual tolerance) through a 25G

butterftlt needle Occasionally smaller or larger doses than those fisted in Table 1 have been used Low doses are often given to elderty or frail patients and to those with

tr)potension Doses for children are loYer than those listed and are reduced roughly 10 proportion to body weight The mos1convnonly used regimen has been 4 ml magnesium 2

ml calc1Um 1 ml each of 812 86 85 and B c~x 6 ml vitamin C and 8 nt sterile water The following is a review of cooditlons successfuly treated with the Myers The

numbers of patients treated and proportion that responded are for the most part estimates

EXHIBIT A - 15

Asthma

Case 1- A five-year-old boy presented with a two-y ear tvstory of asthma OIXlng the previous 12 months he had sufered 20 asthma attacks sever e enough to reqLNre a visrt to the hosprtal emergency department His symptoms appea red to be exacerbated by several foods and s krl tests had been posruve for 23 of 26 inhalants tested His initial trea tment

consisted of identification and avoidance of allergenic foods as welt as daily oral supplementation with Plridoxine (50 mg ) vitamin C (1000 mg) c akium (200 mg ) magnesium (100

mg) and pantothenic acid (100 mg) i1 lwo divided doses with meals On this regimen he experienced marked 1mpnwernem a OO had oo asthma attacks requimg medic al care until

nearty 11 months after his initial visitAt that time the child now-six years old presented for an emergency visK with rrild but persistent wheezing and difficulty breathing _ He was

given a slow IV infusion containing 6 ml vitamin C 1-4 ml magnesium and 05 ml each of calcium B12 B6 85 and 8 comple x_ The sylll)(oms resolved within two 1T11nutes and

did not recurover the ensung eight ye ars and three months he received a total of 63 IVtreatments for acute exacerbations of asthma _ In most instances a single injection resulted

in mar1lted improvement or complete relie f with in iwo minutes and the acute symptoms did not recur_ Occasionalty a second injection was needed after a period of 12 hours to two

days and during one episode three tre atments were requ-ed over a four-day period As the patient grew the nutrient doses were gradualty 1ntreased by age 10 he was receiving

10 ml vitarrin C 3 ml magnesium 15 ml c alcium and 1 ml each of B12 86 B5 and B complex The treatment was unsuccessful only once on that occ asion the patient

presented with generalized llticalia angioedema and unusu alty severe asthma after the inadvertent ingeslloo of an artificial food colofing (FDampC red t40) and other poten tial

allergens Three separate inections giv en ovef a 60-minute period produced transient improvement each time However the symptoms returned and he was taken to the

emergency room and hospitalized Despit e that single treatment failure the patient and his parents reported that IV nutrient therapy wOfced faster produced a more sustained

mprovement and caused considerably fewer side effects than the conventtonal therapies he had received previously in the emergency room The author has treated approx-nately a

dozen asthmatics (mainty adults) with the Myers for acute asthma attacks in most instances marked improvement or c~te relief occurred within ninutes A few patients

received ma1ntenance tnjecllons once weekty or every other week dumg difficult times and reported the treatments kept ther asttvna under better control Intravenous magneslUITI is

rVYW well documented as 311 effective treatment for acut e asthma Jn one studv 38 patients with an acute exacerballoo of modera te-to-severe asthma that had failed to respond to

conventional beta - agonist therapy were randomly assigned to receive in double -blind fashion IV infusions of either magnesrum sulfate (12 g over a 20-mmute period ) Of placebo

(saline 13 Peak expiratory flow rate improved to a significantty greater extent 11 the magnesium group (225 to 2fJ7 U min) than the placebo group (208 to 216 Umin) In addition the

hospitaUation rate was significa ntly lower in the magnesun group than in the placebo group (37 vs 79 p lt 001 ) No patient had a significant drop 11 blood pressuredeg change

in heart rate after receiv ing magnesiumIn a second double-blind study 149 patients wrth acut e asthma who were beflg treated with inhaled beta-agonists and IV steroids wer e

randomly assigned to recetVe an IV infusion of magnesium s ulfate (2 g ovef 20 minutes ) or saline placebo beginning 30 minutes after pres entabon 14 Among patients with severe

asthma (defined as forced expiratory volume in 1 second (FEV1J less than 25 percent of predicted value) compared with placebo magnesium significantly reduced the

hospitalization rate (33 3 vs 786 p lt 001) and significantly improved FEV1 However magnesium treatment was ofno benefit to patients with moderate asthma (defined as

baseline FEV1 between 25 and 75 percent of predicted vakJe) In two placebo-controlled studies of asthmatic children IV magnesium sulfat e sigrvficantly improved pulmonary

function and sign ificantty reduced hospitalization rates dunng acute exacerbations that had failed to respond to conventional therapy 15 16A dose of 40 mg per kg body weight

(maxlfTIUm dose 2 g) grven over a 20-minute penod appeared to be more effective than 25 mg per kg Higher closes of IV magnes1Um sulfate (10--20 g aver 1 hour followed by 04 g

per houf for 24 hours) have been used successfuly In the treatment of ~e-threatening status asthmatic us 6 In a few studies IV magnesitm failed to improve Plbnonary funclloo or to

reduce the need for hospitalization 17 18 However a meta-anatysrs of sev en randomized trials concbied that IV magneslUrTl reduced the need for hospllalizatJon by 90 percent

among patients with severe asthma although the treatment was not beneficial for patients with mcxierate asthma 19Cakium rs the onty other component of the Myers that has been

studied as a treatment for acute exacerbations of asthma In an earty report a series of IV infusions of c alciun chloride relieved asthma sy mptoms in three onsecutive patients with

re lief occurmg almost immediately after some lfljections 20 Intravenous and IM admir1Stration of an unspecified cakrum salt temporarity i-thibited severe anaphylactic reactions in

two other patients2 -5 ml 1--3 ml 1 ml 1 ml 1 ml 1 ml 4-20 ml21Nutrients other than magnesium and calcium may have contributed to the beneficial effect observed in asthma

patients Oral vrtamins C22 and B623 24 and IM vitamin B1225 have each been used with some success against asthma although none of these nutrients has been tested as a

treatment for acute attacks lntrarrusc ular administration of niacinamide has been shown to reduce the severity of experimentalty induced asthma in guinea pigs 26 and pantothenic

acid appe ars to have an anti-allergy effect in humans270n one occasion a patient s asthma attack was treated with IV magnesium alone Although the symptoms resolved rapidly

they returned within 1015 rrwlutes The remaining constituents of the Myefs (wlthout additional magnesium ) were then administered and the symptoms disappeared almost

immediat ety and did not reLm T hus it seems he Myers is more effective than magnesium alone in the treatment of asthma attacks

~graine

Case 12 A 44--year--okl female suffered from frequent migra ines which appeared to be triggered in many instances t7 exposure to environmental chernlcals or occasiooalty to

ingestion of foods to which she was allergic A llergy desensitization therapy had provided little benefit Ovef a six -year period the patient was given IV therapy on approximately 70

occaslOlls for migrames Neal1y al of these lll Jecllons resulted 1n considerable mprovement or complete reief within several minutes although a few treatments we re ineffective

Through trial and error It was detetmned her most effectrve regimen was 16 ml vitallWl C 5 rrt magnesium 4 ml calcium 2 ml B6 and 1 ml each of B12 B5 and B complex The

4--ml close of calcium w as found to provide better relief than tcer calclUITldoses Over the years a half dozen other patients have presented one or more times with an acute

migraine In almost every instance the Myers produced a gratifying response within a few minutes The beneficial elfect of IV magnes ium as a treatment for rrwgraine has been

demonstr ated 111 recent clinical trials In one study 40 patients wnh an acute migra ine received 1 g magnes11in sulfate over a five -mnute period28 Fifteen minutes after the infuslOfl

35 panents (87 5) reported at least a 50--percent reducbon of pain and nine patients (225 ) experienced complete relie f In 21 of 35 patient s who benefiled the improvement

persisted for 24 hours or more Patients with an initia lty low se rum iomzed magnesium coocentration (less than 054 ~ ) were sig nificantly more likely to experience long-tasting

improvement than were patients with initially higher serum ionized magnesi um levels In a single-blind trial that included 30 patients with an acute migraine JV administration of magnesium sulfate ( 1 g over 15 minutes) completely and permanently relieved pain in 13 of 15 patients (866) whereas no patients in the placebo group became pain free (p lt

0001 fOf d ifference between groups)29 In addition magnesium treatment resulted in rapid disappearance of nausea vOOlltrlg and photophobia in all 14 patients who had

experienced thos e symptomsA single 1-g dose of magnesium sutt ate has also been reported to abort an episode of cluster headaches in seven of 22 patients (32) and a series of

th ree to five llfeClions provided sustained relief in an additional two patients (9)301 is not clear whether the Myers is more effective than magnesium alone for migralleS how-ever one pauent did expeneoce noticeable benefit from IV calcium

Fatigue

Many patients with ooexplaIned fatigue have responded to the Myers with results lasting onty a few days or as long as several months Patients who benefited often returned at their own discretion for another treatment when the effect had worn off One patient with fatigue associated w ith chronic hepatitis B expenenced marked and progressrve improvement in

energy levels with weekty or twice -monthly injections Approximately 10 patients with chronic fatigue synd rome (CFS) received a minimum of four treatments (usualty once weekty

for f01Xweeks) with more than half showing clear improvement One patient experienced dramatic benefit after the first inection whereas 1n other cases three or four il)ections were

grven before IITllfOVement was evident A few patients became prog ressrvety healthier with continued inJecllons and were eventually able to stop treatment Severa l others did not

overcome thetr ~lness but periodic WlJeCIIOns helped them function better There rs some research support for the use of parenteral magnesiu m in patients with fatigue One study

found magnesium deficiency demonstrated by an IV magnesium-load test in 47 percent of93 patients with iuexplained chronic fatigue including 50 with CFS 31 In a second study

the mean eryttvocyte magnesium concentration was significantly lower ii 20 patients with CFS than 1n healthy controls32As one arm of the second study 32 patients with CFS

were rMdoovy assigned to receive in double-blind fashion 1 g magnesium sufate IM or placebo onceweekty for six weeks Twetve (80) of 15 patients given magnesium

reported improvement (eg more energy a better emotional stale and less pam) and fatigue was e~minated completely in seven cases In contrast ooJgt three ( 18) of 17 placebo-shy

treated patients improved (p=00015 for difference between groups ) and in no case was the fatigue complet~ elirTlnated AccOfding to one report at least half of CFS patients with

magnesium deficiency benefited from oral magnesium supplementation however some patients needed IM injections33 Other investigators using the IV magnesium-load test

found no evidence of magnesium deficiency in patients with C FS and observed no improvement in symptoms followlng a single infusion of magnesium sulfate (6 gin one

hour) 34Vltamin 812 given IM has been reported to be helpful for patients with ooexplained fatigue 35 as wel as those with CFS 36 While the results obta ined with the Myers may

be attributable in part to vitamin 812 many patients who responded to IV therapy obtained little or no benefit from IM vitamin 812 alone

Fibrom yalgia

Case3 A 48-year -old woman presented w ith a six -year history of fairly constant myalgias and arthralgias with pam in the neck bac k and hip and tightness m the left arm Six

months previousty she was found to have 311 elevated sedimentation rate (50 rrvnlhr) She was diagnosed by a rheumatologist as possibly having polymyalgia rheumallc although

the diagllOSIS of fibromyalgia was also considered Her history was also significant for migraines about eight Imes per year and ctvonic nas al congesllon Phys ic al examinallon

revealed extremety sIff muscles with decreased range of mollon 1n ITlclflf areas of her body The pabent was given a therapeutic tnal consisting of6 ml vrtamm C 4 ml magnesium

2 5 ml calclUfTl and 1 ml each of 812 86 B5 and 8 corrl)lex At the end of the injection she got of the taNe and with a kgtok of amazement announced her muscle aches and join t

pains were gone for the first time in six years This treatment was repeated after a week (at which time her symptoms had not rellnled) followed by every other week flaquo sever al

months then once monthly for three ye ars Her 1nrual regimen also included the idenbfication and avoidance of allergenic foods and treatment with low-dose des c cated thyroid

(eventualty stabilized at 60 mg per day) She discovered that eating refined sugar caused myalgias and arthralgias and that thyrcd hormone improved her energy level mood and

overal well being Dtrilg the three years of montiv maintenance injections she reported symptoms would begin to recur if she went much longer than a month between treatments

However they were never as severe as they were before she began recefVing IV therapyThe author has given the Myers to approximately 30 patients with fibromyalgia half have

expenenced significant improvement in a few cases after the first injection but more often after three or four treatmentsThe beneficial effect of parenteral nutrient therapy- has been

confirmed by one study punished onty as an abstract E ighty-six patients with chronic muscWr complaints including myofascial pain relapsing soft tissue injuries and fibromyalgia

received IM or IV injections of magnesium either alone or in combination with calci um B vitamins and vitamin C37 Improvement occurred in 74 percent of the patients of those 64 percent required four or fewer injections for optimal results A minority of patients requ1red long-term oral or parentera l magnesium to ma1ntain improvement The positive response to

parentera l magnesium is coosrsterit with the observation that nearty half of patien1s with fibromyalgia have intracellular magnesium deficiency despite having normal serum levcls of

the mineral 38

Depression

Case 4 A 46--year--okl man presented with a hJStcxy ofdepressKlO and anxiety since childhood He had been in psychoanalysis for the past eight years A therapeullc trial with IV

nutrients was COflsidered because the patient reported that consumption of akohol (known to deplete magnesium ) aggravated his symptoms and because he was tak1n9 a

magnes1urTHieplet1ng ttuazide diuretic for hypertenslOfl He was lflilla lty grven 1 ml each of magnesMTI 812 B6 85 and 8 complex which resulted in a 70--80 percent reduction in

his sy1)toms for one week A second injection produced a simiar response that lasted two weeks Through trial and enOf it was determined the most effective treatment was 5 ml

magnesium 3 ml 8 complex and 1 ml each of B12 86 and B5 The addition of c alcium to the injection appeared to block some of the benefit Both Ofal and IM adnvnistration of the

same nutrients were tried but found to be nflfective Weekty injections provided almost complete relief from symptoms and allowed him to discontinue psychotherapy The patient

noted that rapidly administered injections provided longer-last ing relief than did slower iiiections The Wlfusion rate was thereflaquoe carefully and progressivety increased without

c ausing any advers e side elects or changes in blood press uredeg heart rate The patient reported that when the treatment was given over a one- m nut e period the effect would last

approximately two weeks whereas a slower injecooo (such as five rmnutes) would lastonty a w eek Approx-nately four years after initial treatment he was able to reduce the

frequency of injections to once monthlylaquo less Many other patients with depressm andfor anxiety have shown a positive response to the Myers However this treatment should

not be considered firs t-Hne therapy for major depressionIt seems to be helpful onty for certain subsets of depressed individuals such as those who also suffef from fibromyalgia

migraines excessive stress or alcohol-induced exacerbations Shealy et al have observed an antidepressant effect of IV magnesium in some paJents with chronic pam 39

Case 5 A 79-year -old man was seen at home in end -stage heart failure aftef having suffered four myocardial infarctions During the prevKgtUS 12 months spent mostly m the

hospital he had become progressively worse his eietllon fraction had fallen to 19 percent and his body weight had declined from 171 pounds toa severely cachecbc 113 pounds

He was conmed to bed and required supplemental oxygen much of the llme He also had severe peripheral occlusive arterial disease which had resulted m the developmen t of

EXHIBIT A - 16

gangrene of SIX toes _ A peripheral angiogram revealed c~le occlusion of both femora lpopliteal arteries wilh no deleltlable blood flow 10 the disla l extremities _ Two ildependent

vascuar surgeons had reconvnended bilateral abovethe - knee amputations to prevent development of septicemia _ However the cardiologist advised the patient that his heart would

not las more than anocher month so the patient declined the amputations _He was treated with weekly IM injections of magnesium sulfate ( 1 g) fOf eight weeks and prescribed oral

supplementation with vitamins C and E B complex folic acid and zinc The magnesium ineclions appeared to reduce the pain in his gangrenous toes considerably with the benefit

lasting about five days each time Six weeks after the first injection his ejection fraction had incre ased from 19 percent to 36 percent and he no longer requiredsupplemental oxygen

After eight weeks the IM injections were replaced by weekly IV injections consisting of 5 ml magnesium 1 ml each of B12 86 B5 and B complex and a low-dose (0-2 ml ) trace

mineral preparation (MTE-5 contain in~r zinc copper chromtUm selenium and manganese ) After a total of 18 months his weight had increased from 113 to 147 pounds which was

remarkable as cardiac cachexia is geoeraly considered to be irreversible In addition the gangrenous areas on his toes had sloughed and been replac ed almost entirely by healthy

tissue Intravenous therapy was conunued and eventually reduced to every other w eek The patlent lived fO( etght years and died at age 87 from multiple organ failure Of the handful

of other patients with angina or heart faillKe who received IV or IM lflte(bons of magnesium (With or without B vitamins ) all showed s igmficant improvement The results with angina

are cons ts tent with those reponed by others using parenteral magnesium theraPi 40-42

Upper Respiratory Tact Infections

Case 6 A 40-y ear -okI male presented wrth a cokI and a one-day history of fatigue nasa l congestion and rtnorrhea He was given an IV 1r1fus1011 of 16 ml vitamin C 3 ml magnesium 15 ml calcium and 1 ml each of B12 B6 B5 and B complex By the end of the 10-rmnutetreatment he was symptom free The cokI symptoms (kj return the next day

but were ooly 10 percent as severe as before the lljection One-quarter to one -tmd of patients who received the Myers for an acute respcratOfY infection experienced marked

improvement either irrmediatefy or by the next morning Approxmatety half of patients given lhis trealment reported that it shortened the duration of the- illness _ Patients who

benefited tended to have a smilar response If treated fOf a subsequent irlfelttion whereas non-responders tended to remain non-responders

Cas e 7 A 32-year--old female had a long history of chronic sinusitis Avoidanc e of allergenic foods and oral supplementation with vitamin C and other nutrients had provided only

minimal benefit She was grven an rv infus1011 of 20 ml vitamin C 4 ml magneslllfll 2 ml calcium and 1 ml each of B12 B6 B5 and B complex this protocol was repeated the

next day At the time these infectlOOS were given she had been experiencing persistent sinus problems for a year Her symptoms resolved rapicly after the injections and she

remained relatJVety symptom free for fTlO(e than six months The same treatment given at a later date was also helpfu although the benefit was not as prOOOUflCed as the first

bmeOne other patient with ch rome s111usltls had a s1m1lar response to back -to-back irecllons while a few others shoYled no improvement

Seasonal Allergic Rhinitis

Case 8 A 38-year-old man had a long history of seasonal allergic rh1mtis occumng each spnng and lasting about a month Symptoms included nasal congestion itchy foes and

faigueOumg a symptomatic period an IV infusion of 12 ml vilamn C 3 ml magnesiun and 1 ml eac h of B12 B6 B5 and B complex provided rapid relief _ Thts treatment was repeated as needed during the hay fever seasoo (once weeklydeg less ) and successfully controlled his symptoms In subsequent years he began the IVs shortly befOfe and

repealed them periodica lly during the hay fever season thrs approach prevented the development of symptoms

Narcotic Wilhdraval

Case 9_ A 35-year--old man addicted to morphine came to the olice in the early stages of withdrawal with diaphoresis and extreme agitation_ He was given an IV infusion of 16 ml

vitarrwn C 5 ml magnesium 2_5 ml calcrum and 1 ml each of B12 B6 85 and B complex _ In his agitated state he was tnable to sit still on the exam table sowe walked up and

down the hall with a butterfly needle in his arm Halfway through the injection he was able to srt still and by the end of the inection his withdrawal symptoms were alleviated The symptoms returned 36 hours later he therefore came for another treatmeflt which again relieved the symptoms within minutes He returned the next day still symptom free for a

third iniection which carried him uneventfully through the remainder of the withdrawal period

Chronic Urtica ia

Case 10 middot A 71-year--old woman had chrorvc urticana with hives present somewhere on her body nearly every day for 10 years An a llerQY-elimnation diet and oral supp4emenlation

wrth vrtamio C and other nutnents provided lrttle or no relief She was grven an IV mfus1011 of 12ml vitamin C 3 ml magnesRKn 15 ml calcium and 1 ml each of B12 B6 B5 and B

complex The same treatment was repeated the folowing day After these inte(tJons the hrves resolved rapidly and did not recur for more than a year When the lesions did recur the

IV treatment was repeated but was ineffectNe

Case 11 An 18-year-Old 235-f)(U7d high school wrestler developed a flu-like ilness four days before a rrJafO( tournament Two days before the ltw-ee-day tournament when it

appeared he rfllJhl have lo RVSs the event he was given an IV bulllion of 16 ml vitarffll C 5 ml magnesium 2-5 ml cakMTI and 1 ml each of B12 B6 B5 and B complex The

next morning he remarked that he had more energf than he had eve- had K1 his life Thts energy boost persisted for the duration of he tournament at which he took second ptace a

better pertOflllallCe than at afff other time in his career_ In th is era in which many athletes are using performance-enhancing drugs it is not the authors intention to encourage

athletes 10 seek arlOlher boos r with IV nutrients _ Havever this case does demonstrate that nutritiooal factors can pampay an important role in physical activities

Hyperth ro1dism

Two patients with hyperthyroidism were treated with the Myers oncedeg tw ice weekty for several weeks_ In one case the treatmen t controled the symptoms of hyperthyroidism

although there was no reduction in thyroid- hormone levels The injections were discontinued after medical theraPf had restored the hormone levels to normal In the other case

sympfnms improvPfl rMrkPlfly illPrthP flffil injPrfinn 1nr11hyrnict-f11nrtinn IPSIS mPISllfM twnw~s lltPr r~tlrMltf In normit TM pnPnti11 VIIIIP nf IV ntnOOllt thPrnPJ for fllliPrlts

with hyperthyroidism is supported by severa l studies Serum and erythrocyte magnesium levels have been found to be low in patients with Graves disease _ 43 l n addition daily IM

injections of magnesium chloride (20 ml of a 14-percent solution ) for 3--7 weeks reduced the size of the thyroid gland and ~oved the clinical condition of three patients with hyperthy roidism44 Intravenous vitamin B6 (50 mg per day ) was reported to relieve muscle weakness JO three patients with hyperthyroidism 45 and animal studies indicate vitamin

B12 can counteract some of the adverse elects of experimentally induced hyperthyrodism4647

Other Conditions

The roodrfied Myers cocktai seems to provide rapid relief for patients wrth acute muscle spasm resulting from sleepwlg in the wroog posrtion or from overuse ti also has been

observed to relieve tension headaches in many cases One pallenl (a 70-year-old female) with chrOflic torticollis expenenced moderate pain relief wrth periodic treatments Of th ree

patients with acute dysmenonhea treated with the Myers two experienced almost instant pain relief _ One patient with chrCXW obstructive pulmonary disease intermittently received

weekly IV injections and reported the treatments itlxoved his strength and breathing

Choice of Ingredients and Admir1stralion

At the time of th is writing cyanocobalamin is a widely available form of inectable vitamin B 12 whereas hydroxocobalamin can be obtained only ttvoogh a compounding pharmacist

Wh ile bofh forms of the vitamin are effective hydroxocobalamin IS preferred because it produces more prolonged increases in serun vitamin B 12 levels-48It has been the author s

impression (and that of other clinicians ) that some patients who respond to IM vnamin B12 injections do no1 experience the same benefit when vitamin B12 is given as part of the

Myers _ ll is poss ible that vitamin C or another component of the Myers destroys some of the vitamin B12 49 or that IV vitamin B12 is lost more rapidly in he urine than lM vitamin

B12 Therefore for some patients receiving IV nutrleflt theraPi lhe vitamn B12 is given IM in a separate syringeInjectable magnes1Um can be obtained either as magnesium chloride

hexahydrate (20 solution ) commonly caned magnesium chloride or magneslUITI sulfate hep(ahydrate (50 sohlllon ) comnonly called magnesium sulfate Although most clinical

research has been done with magnesium sulfate some experts prefer magnesium chloride for rv use because of its greater retention in the body 50 The author has used magnesium

chlonde almost exclusrvely for IV theraPf while reserving the more concentrated magnes ium sulfate for IM administration For those using magnesium sulfate It should be noted that

1 g (2 ml of a SO-percent solution ) is eqU1Valent to 0 8g (4 ml of a 20-percent solution ) of magnesium chloride (each contains 4 mfYlol ofmagneslUfll) ln addit1011 If 50--perceni

magnes1Um sulfate is gNen N instead of 20-percen t magnes ium chloride II should be diluted appropnatety with stenle water Injectable vitamin C is currently avaitable tn

concentrations of 222 and 500 mg per ml The author typica tty uses the lcver concentration for IV therapy tt the higher concentration is used it should be diluted appropriately with

sterile water Occasionalty trace milerals were included as part of a nutrient 111fusion_ The usual dose was O 2-05 ml of MTE -5 which contains (per ml ) zinc 1 mg copper O 4 mg

chromum 4 mcg selernum 20 mcg and manganese o_ 1 mg The preparabonwas diluted six -fold and admirustered over a period of 1-2 ITIIJlUles 1n a separate syringe at the end of

the Myers push_ Two adverse reacllons have been noted with 10 mg of zinc given by slow IV push consequently w hen givJOQ trace minera ls by IV push very small doses are

used Trace rTWlefals should not be mixed in the same synnge with the components of the Myers as doing so often causes formation of a precipitate

Side Effects and Preca ions

The Myers often produces a sensation of heat partxularly with large doses or rapid administration nvs effect appears to be due primarily to the magnesium although rapid

inte(tions of calcium have been reported to produce a similar effect22 The sensation typically begins in the chest and migrates to the vaginal area in women and to the rectal area in

men For most patieflls the heat does not cause excessive discomfort indeed some pabents enjoy ii However if the infusion is given too rapidly the warmth can be overbearing

Some women experience a sensation of sexual pleasure in association wrth the vaginal warmth on rare occasions an orgasm may occurdunng an IV infus1011_ Other patients have

remarked the visual acuity and color perception become sharper immediately after an injecllon as if someone had turned the lights on In some cases this effect lasts as long as

ooe or two days Too rapid administration of magnes ium can cause hypo-tension wh ich can lead to light -headedness or even syncope Patients receiving a Myers should be

advised to report the ooset of excessive heat (which can be a harbinger of hypo tension ) or ligh -headedness If either of these symptoms occurs the infusion should be stopped

temporanry ancl not resumed until the symptoms have resorved (usually aner 10-30 secoods) atients with loW blltXgtd pressure encl to tolerate less magnesium than 00 patients with

normal blood pressure or hypertens1011 In a small proporbon of patients even a lcv-dose regimen given very slowly causes persistent hypo-tens1011 in those cases the treatment is

usuaRy discontinued and may or may not be attempted at a later dateAlthough too raptd adrrinstration can have adverse consequences some patients appear to expenence more

pronounced benefits from rapid 1nfusJOnS than from slcJvier ones presumably because of higher peak serum concentrations of nutrients While both the nsks and benefits should be

taken into account in delermining an lflfusion rate when in doubt one should err on the side of safety Ntlen administering the Myers to a patient fO( the first time it is best to give 05-

1_0 ml and then wait 30 secondsdeg so before proceeding with the rest of the infusion Doing so may help one dislinguish between a vasovagal reaction and a hypertensive response

to the injected compounds _ Patients w ho experience a vasovagal reaction at the beginning of an infusion can usually tolerate the remainder of the treatment after the reaction has

worn of _For elderly or frail individuals it may be advisable to start with lower doses than those listed in Table 1 or to consider IM administration of magnesium and B vitamins as an

alternative to N therapy However many elderly patients have tolerated and benefited from IV therapy Patients who are deficient in both magnesium and potassium may have an

influx of potassium into the ceVs after receiving IV magnesium 51 Th is occurs because magnesium activates the membrane pump that promotes the intracellular uptake of

potasstum The shift of potassium from the serum to the intracellular space can trigger hypokalem la The author has seen two patients develop severe rruscle c ramps several hours

after receiving a Myers both patients had been taking medications known to deplete potassium Hypokalemla also inc reases the nsk of digoxin-lOduced cardiac arrhythmias As a

first -year resident unaware of this potential problem the author administered IV magnesium in the hospital to an elderly WOlllan who was taking digoxin and a potassium---Oepleting

diuretic She quickly developed an arrhythraa which reqlllfed short -term treatment in the intensrve care unitPatients considered 10 be at nsk of potasslllm deficiency lllClude those

laking potasslUOl-deplet rng diuretics beta-agonists or glucocorticoids those wrth diarrhea or vomiting and those who are generally malnourished If a patient is hypokalemic the hypokalemia should be corrected before N magnes ium theraPi is considered However a normal serum potassium concentration is not a guarantee against mtracellular potassium

deplebon FOf patients considered to be at risk of potassium deficiency administration of 10-20 mEq of potassium orally Just prior to the infuslOO and agawl 4-6 hours later is

recOOYTiended After this practice was instituted no further problems With magnesium-induced muscle cramps were encountered The addition of even small amounts of potassium to

an IV push is strongly discouraged because of the theoretical risk of triggering an arrtiythmia during the first pass when the bolus reaches the cardiac conducung

EXHIBIT A - 17

systemIntravenous calc ium is contraindicated in patients taking digoxin_ In addition hypercalcemia can caus e carltiac arrhythmias_ For that reason the author has tended to leave

calcium out of the Myerswhen treating patients with cardiac disease although there is no strong evidence it is dangerous fOf such patients_ Anaphylactic reactions to IV thiamine

have been reported on rare occasions Only three such reactions have been identified in the U_S literature since 1946 However in thewol1d literature a total of nine deaths

attributed to thiamine administration w ere reported between 1965 and 1985 52 These reactions have occurred after oral IY IM or subcutaneous administration and are believed to

be due tn part to a nonspecific re lease of histamine Anaphylactic reactions hav e been seen most often after multiple administrations of thiamine In the United Kingdom between

1970 and 1988 ther e wer e approximat e~ four reports ofanaphylactoid reactions for every million ampules of IV B vitamins sold and one report for every 5 milion IM ampules

sold 531t Is possible the risk of anaphylaxis from the Myers is even loYerthan the loY nsk associated with the use of IV thiamine Many pauents who receive parenteral thianWle are

alcoholics and alcoholtsm frequently causes magnesium deficiency Anmal studies suggest thlamtne supplementation in the presence of magnesrum deficiency increases the seventy of the magnesMJm deficiency 54 Adef1eiency ofmagnes1Um can lead to spontaneous release of histamine 55 and has been reported to n rease the incidence of

expervnentatly induced anaphylaxis in artmals56 The presence of magnesium lf1 the Myers rright therefore reduce the risk of a-1 anaphylactic reaction to thiarnne Moreover as

the Myers has been used successfully to treat asthma an urticana it IS ~kely the formula as a whole provides prophylaxis against anaphylaxis Nevertheless practltloners who

adrruntSter IV nutrients should be prepared to deal with the rare anaphylactic reactionA small number of patients (appro ximately one percent) felt out of sorts for up toa day after

receiving an injection and in two cases this reaction las ted one and two weeks espective~ _ It is not clea r whether these reactions were due to the preservatives in some of the

injectable preparations (e_g_ benzyl alcohol methylparabeos Of others ) Of to the nutrients themselves In most cases lrdJding a few patients with asttma) preservative containing

products were used because the use of multi-dose vials reduced the cost of treatment to the patient_ However for some individuals with known chemical sensitivities or other

signrficant allergy-related problems peservative- free preparations were usedAlthough the Myers is extremefy hypertonic n rarely seemed to cause problems related to its

hypertonicity Two Of three patiems developed phlebitis al the injection site for those patients later treatments were diluted with sterile water to a total of 60 ml Some patients

expenenced a burning sensation at the injection site during the infusion this was often cmec ted by re-positioning the needle or by further diluting the nutrients When administered

wfth caution and respect the Myers middot has been genera~ well tolerated and no senous adverse reac tions have been encount ered with approximately 15000 treatments

Cosl Considerations

In 1995 the authors last year In pnvate practice the cost of the matenals for a Myers was approximately S5 00 The use of preservative-free nutnents at least doubled the cost of

matenals Nurstog trne and adminstrat ive factors represented the maorrty of the cost of IV nutrient therapy In 1995 the author s fee for a Myers w as S3800 Other doctors have

charged as little as $15 00 or as much as S10000 or roore Since 1995 the cost of most of the in)eCtable preparalloos has n reased by 50-100 percentInsurance companies do nol

generally pay for thrs treatment However in a few instances showing them that IV nutrient therapy had greatly reduced the overal cost of the patients health cve persuaded them

to pay

Conclusion

The Myers has been found by the author and hundreds of other practilloners to be a safe and elective treatmer1t fOf a wide range of clinical conditions _ In many ins1ances this

treatment is roore effective and better tolerated than conventional medical therapies_ Although most of the evidence is anecdota l some published research has demonstrated the

efficacy of the Myers or some of its components Widespread appropriate use of this treatment would ~kely reduce the overall cost of healthcare wh ile greatly improving the health

of many individuals_ Additional research is urgently needed to confirm the elfectrveness of this treatment and to determine opbmal doses of the various nutrients _ Although doubleshy

blind trials would be difficult to perfOfm because of the obvious sensations induced by IV nutrient infusions tnals comparing the Myers with established therapies would be

mformative_ Practitioners using this treatment are encouraged to report their findings

References

1 Malkiel-Shapiro B Further observations on parenteral magnesium sulfat e therapy in coronary heart disease a c~lllCal appraisal S Afr Med J 195832 1211-1215 2 Browne SE

Intravenous magnesium sulphate in arterial disease Practruoner 1969202 middot562 -564 3 Blanchard J Tozer TN Rowland M_ Pharmacok inetlC perspectives on megadoses of ascorbic

acid Am J Clin Nutr 1997661165-1171 4 Harakeh S Janwalla RJ Pauling L Suppress10r1 of human mmunodeficieocy VinIS replication by ascorbat e in chronical~ and acutely

infected ceHs Proc Natl Acad Sci US A 199087-7245-7249 5 Okayama H Aikawa T Okayama M et al Bronchodilat 1ng effect of lfltravenous magnesium sulfate in brondual

asthma JAMA 19872571076-1078 6 Sydcv M Crozier TA Ziemann S et al High-dose intraverious magnes ium sulf ate lfl the management of fife-threatening status asthmallcus

lntensrv e Car e Med 199319middot467-4717_ Uchida K Mitsti M Kawakishi s_ vklnooxygenation of N-acetylhistarnne mediated by L-ascorbate Biochlm Biophys Acta 19899913TT-

3798 lsen LT French JH Magnesaim natures physiologic calcium blocker Am Heart J 1984108188-193 9- Brumer EH Delabrorse AM Haddad ZH Effect of parenteral

magnesium on pulmooary hiiction plasma cAMP and histamine in bronchial asthma J Asthma 1985223-1 1 10 FrustaciA Caldarulo M Schiavoni G et al t1yocardial magnesium

content histology and antiarrhythmic response to magnesium infusion_ Lancet 19872middot1019 _ 11_ Henrotte JG_ The variabdity of human red blood eel magnesium level according to

HLA groups_ TSsueAntigens 198015-419-430 _12_ Booth BE Johanson A Hypomagnesemia due to renal tubul ar defect in reabsorption of magnesium _ J Pediatr 197485350-

35413 SkobekllrEM Spivey WH McNamara RM Greenspan L Intravenous magnesium sufate for the treatment of acute asthma In the emergency department JAMA

19892621210-1213_ 14 Bloch H Silverman R Mancherje N et at Intravenous magnes ium sulfate as an adjunct in the treatment of acute asthma_ Chest 1995 1071576-1581_ 15

Ciarallo L Brousseau D Reinert S Higherdose intravenous magnesium therapy for children with moderate to severe acute asthma Arch Pediatr Adolesc Med 2000 154979-98316

Ciaratlo L Sauer AH Shannon MN Intravenous magnesium therapy for moderate to severe pediatric asthma results of a randolTized placebo-controlled trial J Pediatr

1996129 809-81417 Tiffany BR Berilt WA Todd IK oVhne SR Magnesium bolus or infusion fems to improve expiratory flow in acute asttvna exacerbations Chest 1993 104831-

83418 Green SM Rothrock SG Intravenous magnesium for acute asthma failure to decrease emergency treatment duration or need fOf hospitalization_ Ann Emerg Med

199221260-26519 Rowe BH Bretzlalf JA Bourdon C et al Intravenous magnesium s ulfate treatment for ac ute asthma 111 the emergency department_ a systematic review of the

literature Ann Emerg Med 200036 181- 190 20 Pottenger FM A discuss1on of the etiology of asthma in its relationship to the vanous sys tems composing the putmonay

neurocellular mechantSm wtth the physiological basis for the employment of cak1Um In Its treatmentAm J Med Sci 1924167 203--24921 Undritz E The therapy of anaphylacoc

conclitJons with large amooots of calcium J Allergy 19378625 22 Anah CO Jarillte LN Baig HA H igh dose ascorbic acid 111 Nigenan asthmatics Trop Geogr Med 198032 middot132-

137 23 Reynolds RD Natta Cl Depressed plasma pyndoxal phosphate concentratJoos in adult asttvnatics Am J Clin Nutr 198541-684-688 24 CoLipp PJ Golclzier S 3rd ~ss

N et at Pyndoxine treatment of childhood bronct-al asthma_ Am Allergy 19753593--97 25 Crocket JA Cyanocobalamin n asthma ActaAllergologica 19571n61 -268-26 Belltier E Ayc zolk owsk a J Szyc H Maslinskl c_ The inhibitory effect of rncotinamide on asthma-like sy~oms and eosMlOphilia ITT guinea pigs anaphylactic mast cell degrarulatioo lf1

mice and histamine release from ratisolated peritoneal mast cel ls by COfllX)Und 48-80 Int Arch Allergy Appl lnvmnt 197447737-748 27 Tuft L Gregory J Gregory DC_ The effect

of calcium pantothenate on induced whealing and on seasonal rhinitis_ Ann Allergy 195816639-65528_ MauskopA Altura BT Cracco RO Altura BM_ Intravenous magnesium

sulphate relieves migraine attacks m patients with loY serum ionized magnesium levels a pilot study Clin Sci 199589633-63629 _ Demirkaya S Vural O Dora B Topcuog hJ MA

Elfteacy of intravenous magnesium sulfate Ill the treatment of acute migrame attacks Headache 2001 41171-177_30 Mauskop A Altura BT Cracco RO Altura BM Intravenous

magnesium sulfate relieves cluster headaches in patients with k7ltN serum ionized magnesium levels _ Headache 199535597-60031 Manuel y Keenoy B Moorkens G Vertommen

J et aL Magnesium status and parameters of lhe oxidant -antioxidant balance in patients with chltonic fatigue effects of supplementation wtth magnesium J Am Coll

Nutr2000 19 374-382 32 Cox IM Campbell MJ Dowson D Red blood cell magnesium and chltonic fatigue syndrome _ Lancet 1991 337 757-76033 Howard JM Davies S

Hunrvsen A_ Magnesium and chrOOIC fatigue syndrome Lancet 1992340 426 34 Clague JE Ed-Nards RH Jackson MJ Intravenous magnesilKll loading in chron ic fatigue

syndrome Lancet 1992340 124- 125 35 EDis FR Nasser S A pilot study of vitamin 812 in the treatment oflredness Br J Nutr 197330 middot277 -283 36 Lapp CW Cheney PR The rationale for using lqHose cobalamtn (vnamin 812) CFIDS Clvonicle Physicians Forum 1993 (Fal)19-20 37 Reed JC Magnesium therapy in musculoskeletal pain syndromes

~ retrospective review of clime al results_ Magnes Trace Elem 19909330 38 Moorkens G Manuel y Keenoy B Vertommen J et al Magnes ium deficn n a sample of the Belgian

populauon presenting wnh chronic fatigue Magnes Res 199710-329 -337_39 Shealy CN Cady RK Veehof D et al Magnesium deficiency in depresslOJI and ctv-onic pam Magnes

Trace Elem 19909 33340 Malkiel -Shapiro B Bersohn I Temer PE Parenteral magnesium sulphate therapy in coronary heart disease A prehrranary report on ns cfinical and

laboratory aspects Med Proc 19562455-46241 Browne SE_ Magnesium sulphate In arterial disease_ Praclrtioner 19842281165-1166 42 Cohen L Kitzes R Magnesium sulfate in

the treatment of variant angina _ Magnesium 1984 346-49 43_ Disashi T twaoka T Inoue J et aL Magnesium metaboism in hyperthyroidism_ Endocr J 199643397 -402 44 Negu ib

MA_ Ellect of magnesium on the thyroid Lancet 19631140545 Roserba um EE Portrs S Sosk1n S_ The reief of muscular we akness by pyridoxine hyci-ochlonde_ J Lab Clln Med

194127_763-770 46_ Sure B Easterling L The protective action ofvitalTlrl B12 against the toxicity of di-thyroxine_ J Nutr 195042-221-22547_ watts AB Ross OB Whitehair CK

Mac Vicar R Response of castrated male and female hyperthyroid rats to v itamin 812_ Proc Soc Ex p Biol Med 195177624-62648_ Glass GB Skeggs HR Lee DH et al

Applicability ofhydroxocobalamin as a long-acting vit atTlll 812 Nature 1961 189middot138-14049_ Herbert V Vrtamin B12 Am J Cin Nutt 198134971-97250_ Durlach J Bara M

Theophanides T A him on pharmacological and toX1Cological differences between magnes ium chloride and magnesium sulphate or of scalops and men Magnes Res 1996921 7 -

219 51 Dyckner T Wester PO Ventric ular extrasystoles and intracellular electrotytes before and after potassium and magnesium ntusions in patienls on diuretic treatment Am

Heart J 19799712-1852 Stephen JM Grant R Yeh CS Anaphylaxis from administration ofinttaveoous thiamine Am J Emerg Med 19921061-63 53 Cook CC Thomson AD 8-

complex vitamins in the prophylaxis and treatment ofWemicke -Korsakoff syndrome Br J Hosp Med 199757 461-46554 ltokawa Y Tanaka C Kimura M Effec t of thiamine on

serotonin levels m magnesiumdeficient arvmals Metabolism 197221375-379 55 Caddell JL Magnesrum depnvation ITT sooden unexpected infant death Lancet 19722258-262 56

Ashkeoazy Y Moshonov S Ftscher G et at Magnes1um-Oeficient diet aggravates anaphylactJc shock and promotes cardiac myolysis in guinea pigs Magnes Trace Elem

19909-283-288

EXHIBIT A - 18

An-tL ETIC MEDICAL HANGOVER AGE amp BEAUlY MOBIL E SCIENCE

~ 4 101 Cen turion Way ( 8Uy M1lcrnlDbull 41 01 Ce-otulion WayAddisoo TI(

Lmdbergh Or

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8owlmor Dallas G Red Roof Inn ampSurtes0

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At the N Bars we are ready to help you get on the nght lrack for better health

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nutrieflt therapy If you have arr questions or concerns our helpful and caring staff is

available to address all your needs

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EXHIBIT A - 19

8865 Davis Blvd ( Trat

TeK-ArtStone locO

8865 Davis Blvd Soothl1k~ TX 76092

1Glenln ~

WateretEs

QILOV Minis1nes

1865Davis8oulvard

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At the N Bars we are ready to help you get on the nght track for better health

Convernentty located in the heart of Souttiake Texas we are easily access1ble to most Name bull

PHONE (855) 273 -9950

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ADDRESS 8865 Davis Blvd

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HOURS Frida y - Monday (10 am - 2 pm)

Schedule Your Consultation Today There arc two cn y wry to get tarted

1) Cal us at (855) 273-9950 today to speak with our N spec ia~sts They wilt arraoge a

consultation for you with a IV C onsultant who wiB supervise and direct your intrav enous

nutrient therapy If you have any questions or coocems our helpful and caring staff is

available to address aB yoor needs

o 2) Fin in the form on his page and w e will contact you promptly Rest assured hat yotr

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ENHANCE IMMUNITY amp ENERGIZE

HOW IT IIVORKS

iV Bars Ongnal is a functloflal IV lnectioo providwlg replenishing fluids vrtarruns and

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TREAH1ENT

Hectx 2417 llfestyle - such as stress depression headaches a w eakened irrmune

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nutlitJon chOlces

Disc lilmer You should consult you physician befOfe taking vitamns mnefals nutritional supplements Of herbal products Our vitamins and nutritional supplement products on this

site are not intended to diagnose treat cure Of preven t artf disease Final product ingredients and dosages may-vary depending on personal requirements and availablilty

Statements made here have not been evaluated by FDA

EXHIBIT A - 21

An-tL ETIC MEDICAL HANGOV ER AGE amp BEAUlY MOBIL E SCIENCE CONTACT - f middotM

HO1 v IT IIIORKS

N Bars The Performance is a functional IV lnte(tJon providing replenishng fluids

vitarrins mineras and arrvnoacKis befoce during and after all extreme activities

TREATMENT

Extreme Sports - R1n1ing Cycling Swimmlog Soccer Footba ll Hockey Motorsports

Surfing Sky OIVng Snow Boarding Cl imbing Tenrns Boxmg MMA Flying Adventure

and much more

Discl1 i mer You should consult your physician before taking vitamins minerals nutritional suppements Of herbal prOOucts_ Our vitamins and nutntional supplement products on this

site are not intended to diagnose treat cure or prevent artt disease _ Final product ingredients and dosages may vary depending on personal requirements and avaitablilty

Statements made here hav e not been evaluat ed by FDA

EXHIBIT A - 22

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iVoraARS AlHL ETIC MEDICAL HANGOVER AGE amp BEAUTY MOBILE SCIENCE CONTACT _ e~we

HOW TlVORKS

iV Bars Re-Hydrate is a ftntional rv Injection providing replenishing fluids vitamins

minera ls to restoce hydration

TREATMENT

Ex ercise Fatigue General Exhaustion Hangover Skin Complexion Seasonal Illness

Jet -Lag and much more

Di sc liim er You should cons ult yrur physician befor e taking v itamins rrwier als nutritional supplements or herbal products OlK vitarTWS and nutritional supplement products on this

site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages may vary depending on persooal requirements and availablilty

Statements made here have not been evaluated by FDA_

EXHIBIT A - 23

iVoraARS AlHL ETIC MEDICAL HANGOV ER AGE amp BEAUTY MOBILE SCIENCE CONTACT _ e~we

RE JJVEJ HOW T IIIJQRKS

r- Bars Re--wenate ts a funcbonal IV Injection providing rep4ernshing fluids vitarrms

minerals and ammo acids to restore youthful radiance

TREATMENT

Reduce fine roes and wnnkles suppress foonallon of acne and blemishes produce

collagen to enhance elasticity clearer skin and much rnJre

Di scl aimer - You should consult yOIX physician befoce taking v 1tamms rTlrlelals nutritional supplements or herbal products Our vitallllflS and nutritional supplement products on this site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages rTliJy vary depending on persooal requirements and availablilty

Statements made hefe have not been evaluated by FDA

EXHIBIT A - 24

HOW T IIIJQRKS

r- Bars Diet and Detox is a functional JV Injection provdng replenishing fluids vitamins

minerals and ammo acids to bum stubborn body fat detoxify your body to rid It of unhealthy toxins and boos t energy

TREAT1ENT

Boost metabolism and energy detoxify yCXJr vital organs eliminate excess body fat

reduce hunger cravings fit imo those jeans and much more

Disclaimer You should consult you physician before taking vitallVfls minerals nutritional supplements or herba l products OlK vitamins and nutritional supplement products on this

site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages may vary depending on persooal requirements and avaiabl ilty

EXHIBIT A - 25

HOW T IIIJQRKS

r- Bars tnvrune Booster is a functJooal IV l~tion providing repleotsh1ng fluids

vitamins nwJerals and amino acids to combat cold and flu symptoms and get you back

to life

TREAT1ENT

Cold and flu symptoms seasonal allergies reduce oxidative stress protect agDlSt free

radicals boost invwne system and much more

Disclaimer You should consult you physician before taking vitallVfls minerals nutritional supplements Of herba l products OlK vitamins and nutritional supplement products on this

site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages may vary depending on persooal requirements and avaiablilty

EXHIBIT A - 26

(- X i Secur e I htt ps tvbars com trea1ments11btdo

WatingforO wpcom

HOW T IIIJQRKS

r- Bars Libido Enhancer is a functional IV l nJeCIIOll providing replenishing fluids

vitamins nwJerals and amino acids to relax blood ves sels and increase blood flow

TREATMENT

Increased sex dnve stamina energy youthful vrtality boost Testosterone in a natural

way and ITUh more

Di sc laim er You should consult you phys ician befOfe taklnl) vitamns rllrlefals nutritional supplements Of herbal products Our vitamns and nutritional supplement products on this

site are not 1ntended to diagnose treat cure or prevent any disease Fina l product iogreffleflts and dosages may vary depenltfing on personal requirements and availablilty_

EXHIBIT A - 27

HOW T IIIJQRKS

r- Bars Pain Blaster is a funcbonal IV Injection providing rep4ernshing fluids vitarrms

minerals and ammo acids at a cellular level reducng inflanuiabon while ncreasing

circulation

TREAT1ENT

Effective in relieving aches and pains associated with back and rnJScles headaches

teeth menstrual cramps rheJmatic and much more

EXHIBIT A - 28

Cl ~fltXlll bull rVBars

HOW T IIIJQRKS

r- Bars The Focus is a funcbooal IV lnjecbon providing replenish1n9 fluids vrtamins

minerals and ammo acids to wnprove bram perlormance

TREATMENT

Cognrtrve enhancement- focus qlllt ker ltwl kiog problem solving memory attention

sharpness deteITTWalion and much more

Disclaimer You should consult you physician befOfe taking vitalfflls minerals nutritional supplements Of herba l products OlK vitamins and nutritional supplement products on this

site are not intended to diagnose treat cure o prevent any disease Final product ingredien ts and dosages may vary depending on persooal requirements and avaiablilty

EXHIBIT A - 29

CJ NirvaM - NBar

HOW T IIIJQRKS

r- Bars Nirvana is a funcbonal IV lnteetion providing replenrshing fluids vitamins

minerals and ammo acids to boos t the bodys natural serotonin levels and help promote

calmness

TREAT1ENT

Ideal for when - under stress anxious or exhausted to relax muscles chill res

res10re improve mood and much more

-Disclaimer You should consult you physician before taking vitallVfls minerals nutritional supplemenlS or herba l products OlK vitamins and nutritional supplement produclS on this

StatemenlS made here have not been evaluated by FDA

EXHIBIT A - 30

HOW T IIIJQRKS

r- Bars Pure Energy is a functional IM lnecbon providing vllamtns and active

ingredients to keep you energized for days

TREATMENT

Wxkng or playing long hours exercising big race or c~lltlon studying or use to

regulate sleep mood appetite and much more

site are not intended to diagnose treat cure or prevent any disease Final product ingredients and dosages may vary depending on persooal requiremen ts and avaiabl ilty

EXHIBIT A - 31

HOW T IIIJQRKS

r- Bars Anb-Oxid12e is a functional IM lnectJon providing pure L~Gkrtathlone to prevent

damage to lrT1pOrtant cellular components in your body_

TREATMENT

Protect agamt free radicals reduce oxidatlVe stress boost rmITllrle system detoxify

reduce cellular inflanvnation and much more

EXHIBIT A - 32

HOW T IIIJQRKS

r- Bars Myers Cockta il is an Intro Venous V1tamlll lnfus10n wtvch will enhance your

lTVTllXle System Release Fatigue help with Allergies reduce synl)loms of

Fibromyalgia and Asthma

TREAT1ENT

AIi alternative treatment for a broad range of coodiooos includ ing asthma fibromyalgia

chronic fatigue syndrome and even some of those hangover cases

Disclaimer You should consult you phys ician before taking vitallVfls minerals nutritional supplements or herba l products OlK vitamins and nutritional supplement products on this

EXHIBIT A - 33

PRIVAC POLICY

The Effective Date of this Privacy Policy is June 1 2015

surv vARr AND GENERA~ CONTACT INFORI 1ATION

Tots Pnvacy Policy describes how N BARSreg handles mformaboo we learn about you from OU web site The infoonatJon we collect depends on what you do when yoo visit Oll site

If you have questions about this policy orW1Sh to contact us our postal address ts as follows N BARSreg DaRas Texas

COLLECTION AND USE OF INFOR ATION

For each visitor to our web srte w e collect and store the folowing information about your compute r hardvvare and softw are your IP address your browser software your operating

sy stem and the Internet address of the web site from wlwh you inked ltffectly to our srte We collec t and store this llformation on an individual basi s and in aggr egate or conbined

form We also collect both user -specrfic and aggregate information on what pages visitOfS access or visit Thrs information allows us to deliver any mformatioo you request from us

such as product information or tralflng materials _ 11e also use the iofoonation to measure the number of visitors to our site to undffstand which service providers our visitors use 10

improve the content of our web pages and to customize the content and layout of our pages All of this is done with the intention of making our site more useful 10 visitorsOur web

site uses session cookies to record s ess ion information such as wh1eh w eb pages a user has visited and to track user activity on the sile We do not collect any personal data

through the use of cookies and all cookies expire when yoo leave our site Our w eb site does not use persistent cookiesWe do noi collect personally identifying information about

you including your ema il address telephone number or postal address when you visit our site unless you choose to provide such information to us If at any time you do provide us

with such information we will collect ll A reas in which we may collect thts type of information include but are not ~mlled to requests for information regarding OU products and

serv1ees and web site account registration We wil use personally ldenllfying information Ill connection with the purpose forwh1eh you provided rt (eg to contact you with a response

to a request for information ) Addrttonal WWgtfS in which we may use ttus nformabon are as follows If you provide us wrth your email address yoo may receive penodlC promobona l

emails from us with information regardirg special ofers or new products or serv1ees You may also receive informabonal emails from us related to any user accounts you have set

up with us as well as admirvstratrve not1Ces regarding the operabon of the web srtelfyoo supply us with your postal address online you may receive penodic ma ilings from us with

nformallon on new prodocts and serv1tes lfyoo provide us with your telephone number you may receive telephone cootact from us with information regarding new products and servicesWe do not rent or sell email addresses post al addresses or telephone contact information to third parties or otherwise share any personally identifying Wlformanon we

colJect with arrr third parties except that N BARSreg reserves the nght to share personalty identifying 1r1formatJOn with an agent contr actor or partner working on behalf of N BARSreg

to serve our custOOlefS to transfer personalty identify ing Wlformation to a third party in coojuoclioo with the sale or simila r transfer of the company or a business unit and to disclose

personaty identifying nformation to a third party in cooneclioo with legal proceedings and invesligallOOS of crimes or othef wroogdang If N BARsl does share personaty identifying

information with an agent working on behalf of N BARSreg we wil employ commercially apprnpriate procedures to help ensure that the disclosed informatJOn is used only for

authorized purposes by authorized persons and that safeguards are in place to help maintain the security integrity and privacy of the informalion Finally we may keep any

information you voluntarily provide such as survey information andor site registrations both in aggregate and personally identifiable ways

THIRD PARTY SITES

From tme tonme this web site may ~nk you to other sites on the lntemei (Linked Sites ) The Linked Sites are not under N BARSYs control and N BARSreg does nae control the

colJectioo or use of any information 1nCluding personally identifying information that occ urs during your v isit to the linked Sites Further N BARSreg makes no representatlOllS about

the pnvacy policies or practJces of the Linked Sites

OPT OUT PROCEDURES

If you do not wish to receive promobonal emads from us please let us know by using the opt--OUt response device that can be found at the bottom of every email we deliver or by

calling 1V BARSreg at the telephone number indicated in the email (ple ase include sufficient informatlOO to allow us to Identify you IJl our records) Please allow a reasonable time for us

to process your requestNote that although you can opt not to receive promooooal emails N BARSreg retains the nght to send registered use rs of Its web sites lflformatJonal email

messages about the users account or admirnstrative nooces regar ding the site as pemvtted under Texas State law

INFORMATION ACCESS

Upon request we provide site visitors with access to their own personaly Identifying contact information (e g name address phone number) that we mantain about them You can

access this informatJon by sending yoo r request to N BARSreg Dallas Texas To help us process your request please provide sufficient information to allow us to identify you to our

records If you have a user accoum with us we ask that you provide your user name and password in your request We reserve the nght to ask for information verifying your Identity

prior to disclosing any mformation to you Should we ask for venfication the information you provide to verify your Identify will be used only for that purpose and aI copies of thts

nformallon 1n oor possesslOO w ill be destroyed when the process ts cor1)1ete We also offer vtsrtors the opportunity to have nacc1Xaties corrected 1n a8 1nformauon we maintain

about them You can have yOUf 1nformat1011 correc ted by sending your request tomiddot N BARSreg Anentioo middot Customer Service Dallas Texas To helpus process your request please

provide su1f1erent informatlOO to allow us to Identify you in our records

SECURT

We have appropriate securrty measures in place n our phys1eal facilities to protect against the loss rrasuse or alteatJOn of information that we have collected from you al oor site

and we employ secuntv features ~ rally accepted in the industry to protect the securitv of transactions made on our site Corrrnecial transaclioos are protected via Secure

Sockets Layer (SSL ) technology

CHANGES TO THIS POLIC

From time to time we may use c ustomer information for new unanticipated uses not previously disclosed in our privacy ootice If our information pracbces change materially at

some time in the future we will post the policy changes to our web site lfwe have collected personaRy identifying contact information from you we will notify you aboul the changes

prior to making use of your information in new wrys and w il provide you with a reasonable opportunity to opt out of the new procedures before they are implemented We win also

honor opt out requests made following implementation of the new procedures as discussed abov e If you believe that this srte is nae following its stated 1nformation policy yoo may

EXHIBIT A - 34

Terms amp Conditions

Pn1aci

By using this web site andor creating a user account you C011sent to N Bars collection and use of personal 1nformation as discussed in N Bars Privacy Policy which IS hereby

incorporated into these Legal Terms_ A copy of the Privacy Policy can be accessed at https Jrrvbars comprivacy -policy

Use of the V Bars Neb Site

N Bars created and maintains this web site as a service to the public This web site is designed to provide a general oveiview about N Bars and its products and services Please

take a momem to carefully review the folloYing terms and cooditions of use (Terms ) You may access and use this web site at yotK own risk stJqect to all applicable law-s

regulations and the following Terms N Bars reserves the right to update or modify these Terms at any time wnhout prior notice Al materials posted on the NBars website are

currem as of the date posted N Bars expressly disclaims any duty to updat e such information

umted Scope

N Bars controls and operates ttus web srte from rts offices in Texas Due to varying legal and regulatory requrements among different countnes the N Bars proclucts and services

referenced In this web site may not available or amounted lfl y~ country These references do not mply that N Bars mtends to announce such prodocts or services rl your

country

Cop right anlt TrademarK Notices

The entire content included ri this web site includnQ but not limited to text design graphics aff audio or video clips interfaces or code and the selecoon and arrangements thereof

(the Cootent ) are sutiect to the copyright and other intellectual property lights of N Bars and IS copynghted as a collective work under United States amp C artadiari law and appicable

international copyright laws and treaties _ Except as may be expressly stated rl these Terms the Content may oot be reproduced downloaded distributed modified reused

displayed reposted to other w eb sites without firsl obtairwlg N Bars express wnnen permissionAII oflhe names and logos used on this web site for N Bars products and services

and for other prOOucts and services as may be applicable are protected by Uniled States Canadian and foreign trademar1t laws __ A~ folowing a name or logo on our web site

indicales that lhe name or logo is an registered trademark_ All trademarks are the property of their respective owners Except as may be expressly stated in these Terms you may

not reprOOuce display Of otherwise use any N Bars trademark Without first obtaining N Bars s express written perrrissioo

Not a Substitute to Medical Advice

The infOfmation provided on this web site is not intended nor recorrvnended as a substitute fOf professiooal medical advic e Of the instruction on the appropriate use of N Bars s

products or services Pat ients should consult their physician or qual ified health care provider regarding any medical condition or treatment

Discla1rie1 of deg1arbullanties L ~ta on o1 Liab ty THIS WEB SITE AND All CONTENT fAATERIAlS INFORfAATION PRODUCTS AND SERvlCES ARE PROVIDED ON AN AS IS AND middotAs AVAILABLE BAS IS WITHOUT

WARRANTIES OF ANY KIND N Bars AND ITS AFFILIATES DISCLAIM All WARRAN TIES IHETHER EXPRESS IMPLIED OR STATUTORY INCLUDING BUT NOT

LIMITED TO IMPLIED WARRANTIES OF MERCHANT -AB1UTY FITNESS FOR A PAR TICULAR PURPOSE AND NON -INFRINGEMENT N Bars DOES NOT WARRANT OR

MAKE ANY REPRESENTATIONS REGARDING THE USE VALIDITY ACCURACY CURRENCY RELIABILITY OF OR THE RESULTS OF THE USE OF OR OTHERWISE

RESPECTING THIS WEB SITE OR ANY INFORMATION PUBLISHED ON THIS WEB SITE YOU EXPRESSLY UNDERSTAND ANO AGREE THAT UNDER NO

CIRCUMSTANCES Will N Bars ITS AFFILIATES OR ANY OF THEIR RESPECTIVE DIRECTORS OFFICERS EMPLOYEES OR AGENTS BE LIABLE FOR ANY DIRECT

INDIRECT INC IDENTAL CONSEQUENTIAL SPECIAL PUNITIVE OR EXEMPLARY LOSSES OR DAMAGES ARISING OUT OF OR IN CON NECTION WITH THE USE OF

OR INABILITY TO USE THIS WEB SITE OR RELIANCE ON ANY INFORMATION POSTED THROUGH THIS WEB SITE INCLUDING BUT NOT LIMITED TO DAMAGES FOR

LOSS OF REVENUES OR PROF ITS GOODWILL USE DATA OR OTH ER INTANGIBLE LOSS ES SOME JURISDICTIONS DO NOT ALLOW THE EXCLUSION OF

CERTAIN WARRANTI ES OR TH E LIMITATION OF OR EXCL USION OF LIABILITY ACCORDINGLY SOME OF THE ABOVE LIMITATIONS fAAY NOT APPLY TO YOU

Gobull ernng Law and Juisd iction

The use of this web site and any related claim are governed by the laws of the Dallas Texas without regard to its choice oflaw provisions By using this web site you consem to

personal Jurisdictioo in the federal and provincial courts of Dallas Texas This Agreement constitutes the entire agreement between you and N Bars with respec1 to your access to

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