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UCLAUCLA
Nanoscale Measurement System Nanoscale Measurement System Non-confidential summary of UCLA technology available for
licensing, Case reference: LA2004-660
March 18, 2005March 18, 2005Ken PolaskoKen Polasko
Business Development OfficerBusiness Development Officer
Office of Intellectual Property AdministrationOffice of Intellectual Property Administration
www.research.ucla.edu/oipa
(310) 794-8087(310) 794-8087
Nanoscale Measurement System
Markets Force and displacement characterization tools for the nanotechnology market.
Background Construction of hybrid bio-nanosystems relies on measuring and optimizing forces and displacements at the molecular level. The measurement of the forces and displacements involved when attaching biological material to inorganic material or micro electro mechanical systems (MEMS) is becoming an increasing import design capability.
Problem Conventional force transducers (e.g. load sensors) have been the choice for the measurement of forces however these sensors do not have the required sensitivity. Conventional force microscopy relies on cantilever torsional modes for measuring forces along the surface plane, implying in poor visualization and sensitivity. Optical tweezers have been the choice for the measurement of forces produced by single molecules however this techniques has limited force range (pN).
Solution Prototype has been fabricated that can detect forces of ~ 0.2 nN and a corresponding displacement of ~ 40 nm. The prototype incorporates a novel illumination system that permits excellent visualization of biological material. The system design permits flexible handling of liquids. This system fills the gap between existing tools for measuring forces associated with biological elements and purely atomic measurement systems.
Nanoscale Measurement System
Technological StatusTechnological Status
Research Development Commercialization
Discovery TechnicalFeasibility
Integration Prototype Production
Nanoscale Measurement System
Nanoscale Measurement System
Inventors and CollaboratorsInventors and Collaborators Professor Carlo Montemagno, Department of
Bioengineering & Biomedical Engineering Professor Jacob Schmidt, Department of
Bioengineering & Biomedical Engineering Professor Toshikazu Hamasaki, Department of
Bioengineering & Biomedical Engineering Dr. Sergio Freire, Department of Bioengineering &
Biomedical Engineering
Intellectual PropertyIntellectual Property Provisional patent filed
Nanoscale Measurement System
